- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06094582
Knowledges and Use of Cannabidiol in Older Adults (CBD-65)
April 29, 2024 updated by: University Hospital, Toulouse
Knowledges and Use of Cannabidiol in Older Adults Aged 65 Years and Over in France
The use of non-medical cannabidiol (CBD) has been growing recently in France and in the world, in young but also older adults.
Few data are available on the use of cannabidiol in older adults.
A better knowledge of the use of cannabidiol in older adults, and of their own knowledges of the molecule, is necessary to guide and follow the CBD uptake in this population and avoid potential adverse events.
Study Overview
Detailed Description
Cannabidiol may be used by patients because it may have beneficial pharmacological effects (including anxiolytic, analgesic, anti-inflammatories or antioxidant effects).
Older adults aged 65 years and over, are more frequently at risk of multimorbidity and loss of autonomy, and may present with several symptoms like pain, anxiety, sleep disturbances, that may potentially respond to CBD.
The molecule is often marketed as devoid of adverse effects.
Nevertheless, with ageing, reduction in liver and kidney function, may have an impact on the metabolism and elimination of CBD and increase the risk of side-effect.
As well, the risk of interaction with drugs frequently prescribed in older adults such as CYP3A4 inhibitors (verapamil, ketoconazole …), CYP3A4 inducers (phenytoin, carbamazepine, …) or CY92C19 inhibitors or inducers (fluoxetine …), may increase the risk of side effects.
Our hypothesis is that the use of CBD has increased last years in older adults, but that they are insufficiently informed about this molecule.
There is a need to assess the prevalence of CBD use in older adults in France, to assess the knowledges of CBD users about this substance, and to better characterize CBD users.
Study Type
Observational
Enrollment (Estimated)
140
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Sandrine SOURDET, MD
- Phone Number: +33 05 61 77 79 29
- Email: sourdet.s@chu-toulouse.fr
Study Locations
-
-
-
Toulouse, France, 31059
- Recruiting
- University Hospital Toulouse
-
Contact:
- Sandrine SOURDET, MD
- Phone Number: +33 05 71 77 70 74
- Email: sourdet.s@chu-toulouse.fr
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Older Adult
Accepts Healthy Volunteers
Yes
Sampling Method
Non-Probability Sample
Study Population
older adults
Description
Inclusion Criteria:
- admitted to the frailty clinic, in Toulouse University Hospital during the recruitment period.
Exclusion Criteria:
- major cognitive disorder with Mini Mental State Examination <20
- being under legal supervision or guardianship.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Prevalence of CBD use (having consumed CBD at least once)
Time Frame: 1 day
|
The patient will complete a questionnaire about CBD use
|
1 day
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Sandrine SOURDET, MD, University Hospital, Toulouse
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
October 26, 2023
Primary Completion (Estimated)
May 1, 2024
Study Completion (Estimated)
May 1, 2024
Study Registration Dates
First Submitted
October 16, 2023
First Submitted That Met QC Criteria
October 16, 2023
First Posted (Actual)
October 23, 2023
Study Record Updates
Last Update Posted (Estimated)
April 30, 2024
Last Update Submitted That Met QC Criteria
April 29, 2024
Last Verified
April 1, 2024
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- RC31/23/0494
- 2023-A02080-45 (Other Identifier: ID-RCB)
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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