- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06331351
Effect of Jing Si Herbal Tea Liquid Packets on Chronic Pharyngolaryngitis
Effect of Jing Si Herbal Tea Liquid Packets on Chronic Pharyngolaryngitis: A Randomized, Double-blinded Clinical Trial
Chronic pharyngolaryngitis is common and often make people suffer in many aspects. The etiology is numerous, for example, airway hypersensitivity, gastroesophageal acid regurgitation, sicca syndrome, anxiety, etc.
The investigators aimed to investigate the effect of Jing Si herbal tea liquid packets on chronic pharyngolaryngitis by a design of randomized, double-blind clinical trial in this study. The subjects who were bed-ridden, without self-care ability, receiving hemodialysis, no idea about the details of this study, poor compliance for this study, alcohol and/or drugs additives, pregnancy and breast-feeding women were excluded from this study.
A questionnaire for health and habits was performed at the start of the study, and a questionnaire for Reflux Symptom Index (RSI) was performed at the start and the end of the study. Finally, Student's t-test was used to test the difference between the Jing Si herbal tea group and the control group. And, multivariate linear regression was used to test the violation of clinical factors on the treatment outcome of Jing Si herbal tea liquid packets on chronic pharyngolaryngitis.
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Chronic pharyngolaryngitis is common and often make people suffer in many aspects. The etiology is numerous, for example, airway hypersensitivity, gastroesophageal acid regurgitation, sicca syndrome, anxiety, etc.
The investigators aimed to investigate the effect of Jing Si herbal tea liquid packets on chronic pharyngolaryngitis by a design of randomized, double-blind clinical trial in this study. One hundred and twenty adults of both sex with a range of age between of 20-70 years old were included. All participants were divided randomly into two groups. Jing Si herbal tea group received 1 pack of Jing Si herbal tea liquid packet twice a day for 1 month (30 days), and the control group received 1 pack of control liquid packet twice a day for 1 month (30 days). The subjects who were bed-ridden, without self-care ability, receiving hemodialysis, no idea about the details of this study, poor compliance for this study, alcohol and/or drugs additives, pregnancy and breast-feeding women were excluded from this study.
A questionnaire for health and habits was performed at the start of the study, and a questionnaire for Reflux Symptom Index (RSI) was performed at the start and the end of the study. Finally, Student's t-test was used to test the difference between the Jing Si herbal tea group and the control group. And, multivariate linear regression was used to test the violation of clinical factors on the treatment outcome of Jing Si herbal tea liquid packets on chronic pharyngolaryngitis.
Study Type
Enrollment (Estimated)
Phase
- Not Applicable
Contacts and Locations
Study Contact
- Name: Juen-Haur Hwang, MD, PhD
- Phone Number: 5239 +886-5-2648000
- Email: g120796@tzuchi.com.tw
Study Locations
-
-
-
Chiayi City, Taiwan, 66247
- Recruiting
- Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
-
Contact:
- Juen-Haur Hwang, MD, PhD
- Phone Number: 5239 +886-5-2648000
- Email: g120796@tzuchi.com.tw
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Description
Inclusion Criteria:
- Adult men and women aged 20 to 70 years old.
- Patients with chronic pharyngitis
Exclusion Criteria:
- Patients who are bedridden or unable to take care of themselves.
- Dialysis patients.
- Patients who cannot understand the details of this study or cannot cooperate with the examination.
- History of alcohol or drug abuse.
- Pregnant and lactating women
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Other
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Double
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Placebo Comparator: control group
placebo: 2 times a day, 1 sachet each time.
|
2 times a day, 1 sachet each time.
Other Names:
|
Experimental: Jing Si herbal tea liquid packets group
Jing Si herbal tea liquid packets: 2 times a day, 1 sachet each time.
|
2 times a day, 1 sachet each time.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Health questionnaire
Time Frame: Before the test begins and after intervention completed (at 1 month)
|
the recording items are as follows: age, gender, height, weight, waist circumference, disease history, smoking or not (quantification), drinking or not (quantification), and eating betel nut or not (quantification) , sleeping status, whether to drink coffee (quantification)
|
Before the test begins and after intervention completed (at 1 month)
|
Reflux Symptom Index (RSI)
Time Frame: Before the test begins and after intervention completed (at 1 month)
|
The Reflux Symptom Index (RSI) is in common use as a semi-quantitative tool to assess symptoms associated with laryngopharyngeal reflux (LPR). RSI is a scoring tool that consists of nine items used to assess various symptoms associated with LPR. Each item has a scale ranging from zero (no complaints) to five (severe complaints), with a maximum of 45 indicating the most severe symptoms. |
Before the test begins and after intervention completed (at 1 month)
|
Collaborators and Investigators
Sponsor
Investigators
- Study Chair: Juen-Haur Hwang, MD, PhD, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- A11203001
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Chronic Pharyngitis
-
Vastra Gotaland RegionGöteborg University; James Cook University, Queensland, AustraliaCompletedTonsillitis | Pharyngitis | Sore Throat | Streptococcus Pharyngitis | Pharyngitis BacterialSweden
-
Andrew SteerNational Health and Medical Research Council, Australia; Queen Fabiola Children... and other collaboratorsCompletedBacterial Infections | Gram-Positive Bacterial Infections | Strep Throat | Streptococcus Pharyngitis | Streptococcus Pyogenes Pharyngitis | Streptococcus Pyogenes Infection | Group A Streptococcus: B Hemolytic Pharyngitis | Group A Streptococcal InfectionAustralia
-
Hillel Yaffe Medical CenterUnknownChronic Tonsillitis
-
Luminex CorporationCompletedPharyngitis BacterialUnited States
-
Hamilton Health Sciences CorporationRecruiting
-
University of Wisconsin, MadisonNational Institute of Allergy and Infectious Diseases (NIAID)Recruiting
-
Dentaid SLMethodexRecruiting
-
Northwell HealthIcahn School of Medicine at Mount Sinai; Agency for Healthcare Research and...CompletedPneumonia | Strep PharyngitisUnited States
-
Oman Medical Speciality BoardCompleted
-
Megainpharm GmbHTerminated
Clinical Trials on control group
-
Tasly Pharmaceutical Group Co., LtdCompleted
-
M.D. Anderson Cancer CenterNational Cancer Institute (NCI); National Institutes of Health (NIH)Completed
-
Henan Cancer HospitalRecruitingChemotherapy | Immune Checkpoint Inhibitor | Locally Advanced Gastric CarcinomaChina
-
International University of La RiojaRecruiting
-
The University of Hong Konghong Kong Cancer FundCompletedBreast Cancer | Yoga Therapy | Shoulder Joint Motion | Scar Contracture
-
Romanian Society of Anesthesia and Intensive CareUniversity of Medicine and Pharmacy "Victor Babes" Timisoara; Timişoara County...Completed
-
University of MaltaNot yet recruiting
-
University of PernambucoUnknown
-
Yonsei UniversityUnknownAdvanced Gastric Cancer | Neoadjuvant Chemotherapy | Palliative ChemotherapyKorea, Republic of
-
Physicians Committee for Responsible MedicineMetropolitan Police Department of Washington, D.C.SuspendedDiabetes Mellitus, Type 2 | Overweight | Blood PressureUnited States