- ICH GCP
- US Clinical Trials Registry
- Klinisk forsøg NCT03396458
Hepatitis B Prevalence in the Turkish Population Living in Middle Limburg (HBVTR)
Prevalence and Risk Factors of Hepatitis B Viral Infection in the Turkish Population Living in Belgium
Studieoversigt
Status
Betingelser
Intervention / Behandling
Detaljeret beskrivelse
HBV infection is an important public health problem in the Turkish population, i.e. one of the largest migrant populations in Europe. With the introduction of cost-effective antiviral treatments in the past decade, there is a need to identify HBV infected patients who may benefit from treatment. This study will assess the HBV prevalence in the Turkish population living in Belgium. Additionally, the investigators will determine the risk factors of HBV infection and the uptake of screening, vaccination and antiviral treatment in this hard-to-reach Turkish population.
A cross-sectional, epidemiological trial will be conducted in the region Middle Limburg Belgium, where the Turkish adult population (subjects born in Turkey or subjects of which one of the parents is born in Turkey), 18 years of age and older, will be screened for HBsAg, anti-HBs and anti-HBc. Educational meetings concerning viral hepatitis B will be organized and there will be three ways to be screened for HBV: (1) immediately after the educational meetings, (2) at the Outpatient Hepatology Department of Ziekenhuis Oost-Limburg (ZOL) and (3) at home visits. Subsequently, participants will be asked to fill in a questionnaire regarding sociodemographic factors, migration history, risk factors for HBV infection (e.g. sharing toothbrushes, HBV infected family member) and HBV vaccination status. One year after data collection, HBsAg positive patients will be assessed whether they are under follow-up at the general practitioner or hepatologist. The investigators will also gather information regarding the uptake of vaccination in non-immunized subjects.
This study will provide information about the HBV prevalence and distribution of the stages of liver disease in the Turkish population in Belgium. By determining the risk factors for HBV infection, subgroups with an increased prevalence of HBV infection can be identified. This study will also give information on how to organize the healthcare system for screening in hard-to-reach migrant groups and to develop care paths.
Undersøgelsestype
Tilmelding (Forventet)
Kontakter og lokationer
Studiekontakt
- Navn: Geert Robaeys, M.D., Ph.D.
- Telefonnummer: +3289326505
- E-mail: geert.robaeys@zol.be
Undersøgelse Kontakt Backup
- Navn: Özgür Koc, M.D.
- Telefonnummer: +3289321519
- E-mail: ozgur.koc@zol.be
Studiesteder
-
-
Limburg
-
Genk, Limburg, Belgien, 3600
- Rekruttering
- Ziekenhuis Oost-Limburg
-
Kontakt:
- Geert Robaeys, M.D., Ph.D.
- Telefonnummer: +3289326505
- E-mail: geert.robaeys@zol.be
-
Kontakt:
- Özgür Koc, M.D.
- Telefonnummer: +3289321519
- E-mail: ozgur.koc@zol.be
-
-
Deltagelseskriterier
Berettigelseskriterier
Aldre berettiget til at studere
Tager imod sunde frivillige
Køn, der er berettiget til at studere
Prøveudtagningsmetode
Studiebefolkning
Beskrivelse
Inclusion Criteria:
- Turkish origin, defined as one of the parents born in Turkey
- Having a signed informed consent form
Exclusion Criteria:
/
Studieplan
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
Kohorter og interventioner
Gruppe / kohorte |
Intervention / Behandling |
---|---|
Hepatitis B group
Hepatitis B serology and questionnaire
|
A serum specimen will be taken and assessed for hepatitis B serology (HBsAg, anti-HBs and anti-HBc).
Participants will be asked to fill in a questionnaire regarding sociodemographic factors, migration history, risk factors for HBV infection (e.g.
sharing toothbrushes, HBV infected family member) and HBV vaccination status.
|
Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
---|---|---|
Seroprevalence of current HBV infection in the Turkish population
Tidsramme: 1 day
|
Serum HBsAg
|
1 day
|
Sekundære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
---|---|---|
Seroprevalence of protective antibodies against HBV infection in the Turkish population
Tidsramme: 1 day
|
Serum anti-HBs
|
1 day
|
Assess risk factors for past or current HBV infecion in the Turkish population
Tidsramme: 1 day
|
Combine results from (1) serum anti-HBc with (2) questionnaire regarding sociodemographic factors, migration, risk factors for HBV infection and HBV vaccination status
|
1 day
|
Samarbejdspartnere og efterforskere
Sponsor
Publikationer og nyttige links
Datoer for undersøgelser
Studer store datoer
Studiestart (Faktiske)
Primær færdiggørelse (Forventet)
Studieafslutning (Forventet)
Datoer for studieregistrering
Først indsendt
Først indsendt, der opfyldte QC-kriterier
Først opslået (Faktiske)
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
Sidst verificeret
Mere information
Begreber relateret til denne undersøgelse
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- HBVTR-1.0
Plan for individuelle deltagerdata (IPD)
Planlægger du at dele individuelle deltagerdata (IPD)?
Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter
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