NEAT - Prevention and Treatment of Overweight and Obesity. (InphactUm)

May 10, 2016 updated by: Tommy Olsson, Umeå University

Non-exercise Activity Thermogenesis (NEAT) - Prevention and Treatment of Overweight and Obesity

This study will investigate the effect on Non-exercise Activity Thermogenesis (NEAT) when implementing active workstation at offices compared to conventional office work. The primary hypothesis is that this implementation will lead to a significant increase in time spent walking per day.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

NEAT consists of the energy expenditure of the physical activities that are non sporting-like and that we perform in our everyday life, such as walking, cleaning, shoveling snow etc. Which occupation we have play a big role in how much we are able to active our NEAT during our days and those who have more active jobs can expend up to 1500kcal more per day than those with sedentary jobs.

This study aims to try and increase NEAT at offices where sedentary time often is high. Participants will be randomized to either an intervention group or to a control group. Participants in the control group will continue to work at their regular desk, but will receive an individual health talk in the beginning of the study where diet and physical activity recommendations will be discussed.Participants in the intervention group will receive the same individual health talk and a treadmill desk, which they will use for 12 months at self-selected speed. They will be recommended to walk on the treadmill for at least 1 hour per day.

Study Type

Interventional

Enrollment (Actual)

80

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Sweden
      • Umeå, Sweden
        • Umea University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

40 years to 67 years (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Office workers with mainly sedentary tasks
  • BMI 25-40

Exclusion Criteria:

  • Severe depression and/or anxiety
  • Exhaustion disorder
  • Diabetes Mellitus
  • Severe cardiovascular disease
  • Severe kidney disease
  • Musculoskeletal disorders that prohibit walking on a treadmill
  • Contraindications for physical activity
  • Thyroidea illness
  • Pregnancy

For fMRI-study, additional exclusion criteria are:

  • Implanted metal- or electrical devices
  • Pregnancy
  • Extraneous metal pieces in the body

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Treadmill workstation
Will receive a health talk with recommendations about diet and physical activity habits and will also receive a treadmill workstation at regular office site for 12 months.
Behavioral: Treadmill workstation
The intervention group will receive a treadmill workstation for 12 months. They will use this at self-selected speed and will be recommended to use this for at least 1 hour per day. Participants in the control group will continue with conventional office work at their regular desk. Participants in the intervention group will receive four boosting e-mails during the study period, in which they will be encouraged to use the treadmill.
Behavioral: Health talk
Participants in both groups will receive a health talk with recommendations about diet and physical activity habits.
Experimental: Control group
Will receive a health talk with recommendations about diet and physical activity habits. Will continue to work with conventional office work at their regular desk.
Behavioral: Health talk
Participants in both groups will receive a health talk with recommendations about diet and physical activity habits.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change from baseline in physical activity and sedentariness at 12 months
Time Frame: Baseline, 12 months
Measured with an accelerometer (ActiGraph) and an inclinometer (ActivPAL).
Baseline, 12 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change from baseline in metabolism at 12 months
Time Frame: Baseline, 12 months
Metabolism: 2h glucose tolerance test. lipids, Hb1Ac
Baseline, 12 months
Change from baseline in anthropometrics at 12 months
Time Frame: Baseline, 12 months
Length, height, weight, waist circumference, hip circumference, sagittal height, pulse, blood pressure.
Baseline, 12 months
Change from baseline in body composition at 12 months
Time Frame: Baseline, 12 months
Measured with Dual X-Ray Absorptiometry (DXA)
Baseline, 12 months
Change from baseline in musculoskeletal pain at 12 months
Time Frame: Baseline, 12 months
Measured with the Chronic Pain Grade Questionnaire
Baseline, 12 months
Change from baseline in stress at 12 months
Time Frame: Baseline, 12 months
Measured by assessing cortisol levels in the saliva at 4 time points during one day. Also measured with the stress- and energy scale.
Baseline, 12 months
Change from baseline in depression/anxiety at 12 months
Time Frame: Baseline, 12 months
Measured with the Hospital Anxiety and Depression Scale.
Baseline, 12 months
Change from baseline in Quality of Life at 12 months
Time Frame: Baseline, 12 months
Measured with 2 questions from the SF-36.
Baseline, 12 months
Change from baseline in cognitive Function and functional brain response at 12 months
Time Frame: Baseline, 12 months
Measured with a cognitive test battery and functional MRI (fMRI). Levels of Brain-Derived Neurotrophic Factor (BDNF) is measured in the plasma.
Baseline, 12 months
Qualitative interview study
Time Frame: 12 months
Participants will be interviewed about experiences from being part of the study and about attitudes and factors that influences them to be physically active.
12 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Umeå University

Investigators

  • Principal Investigator: Tommy Olsson, Professor, Umea University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

February 1, 2014

Primary Completion (Actual)

December 1, 2015

Study Completion (Actual)

December 1, 2015

Study Registration Dates

First Submitted

November 2, 2013

First Submitted That Met QC Criteria

November 22, 2013

First Posted (Estimate)

November 28, 2013

Study Record Updates

Last Update Posted (Estimate)

May 12, 2016

Last Update Submitted That Met QC Criteria

May 10, 2016

Last Verified

May 1, 2016

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2013-338-31

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Obesity

Clinical Trials on Treadmill workstation

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Morocco

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

3
Subscribe