Observation Versus Post-surgery Radiotherapy After Complete Exeresis in Soft Tissues Members Sarcoma

Inclusion Criteria:

• Soft tissue sarcoma members histologically confirmed
• Tumor primitive complete excision with margins greater than or equal to 10 mm in the soft tissue in all directions during the initial surgery.

A sub-centimeter margin is authorized under an anatomic barrier (fascia, fascia, inter-osseous membrane, periosteum), if surgery is R0 a margin sub-centimeter depth is allowed for superficial tumors if the underlying fascia RESECTED is not invaded.

• Primitive tumors without breaking initial tumor and without tumor residue in the systematic recovery in case of incomplete initial excision margins or doubtful
• WHO less than or equal to 2
• Age greater than or equal to 18 years
• Review extension negative (normal chest CT)
• Information and monitoring possible
• Patient affiliated to social security

Exclusion Criteria:

• Previously treated local sarcoma relapse
• Visceral or lymph node metastases
• pre-operative treatment (chemotherapy or radiotherapy)
• PNET, alveolar rhabdomyosarcoma, Darrier-Ferrand sarcoma
• excision margins of less than 10 mm in one direction or doubtful or unspecified, except under an anatomic barrier (fascia, fascia, inter-osseous membrane, periosteum), if surgery is R0 and tumors if the superficial fascia underlying RESECTED is not invaded.
• Break-tumor during the initial surgery, or residual tumor at second surgery
• Chemotherapy
• Delay between surgery R0 margins greater than or equal to 1 cm (initial surgery or recovery) and the start of radiotherapy exceeding 8 weeks
• History of radiation on the Member
• History of cancer (except carcinoma in situ of the cervix and basal cell skin cancer or in complete remission for over 5 years)
• Pregnant Women
• Patients under guardianship or curatorship