- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01845571
Retinal Detachment - Demographic and Clinical Survey
Long-term Anatomic and Funcional Succes After Surgery in Eyes With Retinal Detachment
Background:
Rhegmatogenous retinal detachment is an ophthalmic emergency that, without surgical repair, often leads to blindness. The incidence is about 1/10000/year. The leading causes are myopia and aging which cause retinal tears often resulting in retinal detachment. Patients commonly experience photopsia, floaters, and peripheral visual field loss.
Two different general surgical treatment options exist for retinal detachment; scleral buckling or vitrectomy. However, the precise indications for each approach have not been well established. Correct classification of the retinal detachment is important. The first step is to decide whether an intra- or extra-ocular surgical approach is more appropriate. Simple rhegmatogenous retinal detachments are usually treated extraocularly with scleral buckling surgery, whereas more complicated cases require intraocular primary pars plana vitrectomy and one or more of gas, silicone oil, laser therapy, or cryotherapy.
Study objectives:
The purpose of this study is to evaluate different surgical techniques for the treatment of retinal detachment. Data relating to retinal status before treatment, surgical treatment, post-operative anatomy and visual acuity, post-operative OCT, and intra- and post-operative complications will be collected.
Vitreous cytokines will also be analyzed to monitor intravitreal inflammation as a result of retinal detachment.
Study Overview
Status
Conditions
Study Type
Enrollment (Anticipated)
Contacts and Locations
Study Locations
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Vienna, Austria, 1090
- Recruiting
- Insitute of Ophthalmology and Optometry, Medical University of Vienna
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Contact:
- Stefan Sacu, Prof
- Phone Number: 40400 - 7970
- Email: stefan.sacu@meduniwien.ac.at
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
Patients who received surgery due to retinal detachment between January 2008 and Decemebr 2012.
Surgery was performed by either Ass.Prof.PD.Dr. Stefan Sacu or Prof.Dr. Michael Georgopoulos
Exclusion Criteria:
If patients had prior vitrectomy or scleral buckel. If patients had no adequate follow-up.
Study Plan
How is the study designed?
Design Details
- Observational Models: Case-Only
- Time Perspectives: Other
Cohorts and Interventions
Group / Cohort |
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Retinal detachment group
400 patients patients, who received surgery due to retinal detachment exclusion: if patients had prior vitrectomy or scleral buckel if patients have no adequate follow-up
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Vision
Time Frame: 2 years
|
2 years
|
Aqueous cytokine Levels
Time Frame: baseline
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baseline
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Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
OCT
Time Frame: baseline
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baseline
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Surgical Data
Time Frame: 2 years
|
2 years
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Stefan Sacu, Prof, Medical University of Vienna
Study record dates
Study Major Dates
Study Start
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 13.12.2011
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
product manufactured in and exported from the U.S.
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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