Retinal Detachment - Demographic and Clinical Survey

Long-term Anatomic and Funcional Succes After Surgery in Eyes With Retinal Detachment

Sponsors

Lead Sponsor: Medical University of Vienna

Source Medical University of Vienna
Brief Summary

Background:

Rhegmatogenous retinal detachment is an ophthalmic emergency that, without surgical repair, often leads to blindness. The incidence is about 1/10000/year. The leading causes are myopia and aging which cause retinal tears often resulting in retinal detachment. Patients commonly experience photopsia, floaters, and peripheral visual field loss.

Two different general surgical treatment options exist for retinal detachment; scleral buckling or vitrectomy. However, the precise indications for each approach have not been well established. Correct classification of the retinal detachment is important. The first step is to decide whether an intra- or extra-ocular surgical approach is more appropriate. Simple rhegmatogenous retinal detachments are usually treated extraocularly with scleral buckling surgery, whereas more complicated cases require intraocular primary pars plana vitrectomy and one or more of gas, silicone oil, laser therapy, or cryotherapy.

Study objectives:

The purpose of this study is to evaluate different surgical techniques for the treatment of retinal detachment. Data relating to retinal status before treatment, surgical treatment, post-operative anatomy and visual acuity, post-operative OCT, and intra- and post-operative complications will be collected.

Vitreous cytokines will also be analyzed to monitor intravitreal inflammation as a result of retinal detachment.

Overall Status Recruiting
Start Date October 2011
Completion Date December 2020
Primary Completion Date December 2020
Study Type Observational
Primary Outcome
Measure Time Frame
Vision 2 years
Aqueous cytokine Levels baseline
Secondary Outcome
Measure Time Frame
OCT baseline
Surgical Data 2 years
Enrollment 400
Condition
Eligibility

Sampling Method: Non-Probability Sample

Criteria:

Inclusion Criteria:

Patients who received surgery due to retinal detachment between January 2008 and Decemebr 2012.

Surgery was performed by either Ass.Prof.PD.Dr. Stefan Sacu or Prof.Dr. Michael Georgopoulos

Exclusion Criteria:

If patients had prior vitrectomy or scleral buckel. If patients had no adequate follow-up.

Gender: All

Minimum Age: 18 Years

Maximum Age: N/A

Healthy Volunteers: No

Overall Official
Last Name Role Affiliation
Stefan Sacu, Prof Principal Investigator Medical University of Vienna
Location
Facility: Status: Contact: Insitute of Ophthalmology and Optometry, Medical University of Vienna Stefan Sacu, Prof 40400 - 7970 [email protected]
Location Countries

Austria

Verification Date

June 2020

Responsible Party

Type: Principal Investigator

Investigator Affiliation: Medical University of Vienna

Investigator Full Name: Stefan Sacu

Investigator Title: Ass.Prof.PD.Dr.

Has Expanded Access No
Condition Browse
Arm Group

Label: Retinal detachment group

Description: 400 patients patients, who received surgery due to retinal detachment exclusion: if patients had prior vitrectomy or scleral buckel if patients have no adequate follow-up

Study Design Info

Observational Model: Case-Only

Time Perspective: Other

Source: ClinicalTrials.gov