Introduction of a Massive Transfusion Protocol - Evaluation Over Three Years

Massive Transfusion Protocol With Coagulation Algorithm

Sponsors

Lead sponsor: University of Zurich

Source University of Zurich
Brief Summary

In 2008 at the University Hospital Zurich (USZ) a massive transfusion protocol was introduced. Based on laboratory diagnostics and point of care (POC) devices including ROTEM.

Goal of this retrospective study is to evaluate the influence of this algorithm on coagulation, use of blood products, coagulation factors and ROTEM evolution.

Detailed Description

In 2008 at the USZ a massive transfusion protocol was introduced. Based on laboratory diagnostics and POC (point of care) devices including ROTEM.

Goal of this retrospective study is to evaluate the influence of this algorithm on coagulation, use of blood products, coagulation factors and ROTEM evolution over three years (2008-2010)

Overall Status Completed
Start Date January 2010
Completion Date December 2012
Primary Completion Date December 2012
Study Type Observational
Primary Outcome
Measure Time Frame
Coagulation in ROTEM 3 years
Secondary Outcome
Measure Time Frame
Transfusion needs 3 years
Enrollment 243
Condition
Intervention

Intervention type: Device

Intervention name: Rotational thromboelastometry

Description: In bleeding patients point of care measurements are performed, in this case Rotational Thromboelastometry (ROTEM) to guide the use of blood products and coagulation factors.

Eligibility

Sampling method: Non-Probability Sample

Criteria:

Inclusion Criteria:

- Massive transfusion

Exclusion Criteria:

- non

Gender: All

Minimum age: 18 Years

Maximum age: N/A

Healthy volunteers: No

Verification Date

January 2015

Responsible Party

Responsible party type: Principal Investigator

Investigator affiliation: University of Zurich

Investigator full name: Oliver Theusinger

Investigator title: PD Dr med

Has Expanded Access No
Condition Browse
Study Design Info

Time perspective: Retrospective

Source: ClinicalTrials.gov