- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03325140
Platelet Transfusions in Critically Ill Patient (RE-CCIP)
Platelet Transfusion Efficacy in Critically Ill Patients
Between 10 and 15% of critically ill patients require platelet transfusion within their intensive care unit (ICU).
Platelets (PLT) are given to prevent bleeding in thrombocytopenic patients or to treat bleeding as part of massive transfusion or in bleeding thrombocytopenic patients.
International and local guidelines (American Association of Blood Banks-AABB) are mainly based on experts' opinion. The efficacy of PLT transfusion in the ICU setting remains poorly studied and unknown and the administration of PLT may be associated with adverse effects including an increased risk of hospital acquired infection. Finally, the short PLT shelve-life may be responsible for inventory issues. Altogether, this makes very important to improve the evidence that support PLT transfusion in ICU patients.
This is a multicentre prospective observational study that aims to first determine PLT transfusion efficacy and to identify the parameters associated with transfusion efficacy and to analyse the compliance with international (and local) guidelines of PLT transfusion in ICU patients.
Study Overview
Status
Conditions
Study Type
Enrollment (Anticipated)
Contacts and Locations
Study Locations
-
-
-
Angers, France, 49100
- Recruiting
- CHU d'Angers
-
Contact:
- Pierre ASFAR, Pr
- Email: pierre.asfar@chu-angers.fr
-
Brest, France, 29609
- Recruiting
- CHRU de Brest
-
Contact:
- Aubron Cécile
- Email: cecile.aubron@chu-brest.fr
-
Sub-Investigator:
- Olivier Huet, Pr
-
Morlaix, France, 29 672
- Recruiting
- CH des Pays de Morlaix
-
Contact:
- Pierre-Yves EGRETEAU
- Phone Number: 02 98 62 61 60
- Email: pyegreteau@ch-morlaix.fr
-
Nantes, France, 44093
- Recruiting
- Chu De Nantes
-
Contact:
- LE MEUR Anthony
- Email: anthony.lemeur@chu-nantes.fr
-
Rennes, France, 35033
- Recruiting
- CHU de Rennes
-
Contact:
- SEGUIN Philippe
- Email: philippe.seguin@chu-brest.fr
-
Sub-Investigator:
- TADIE Jean-Marc
-
Tours, France, 37044
- Recruiting
- CHU de Tours
-
Contact:
- EHRMANN Stephan
- Email: stephan.ehrmann@chu-tours.fr
-
Vannes, France, 56 017
- Recruiting
- Chba Site de Vannes
-
Contact:
- Julien HUNTZINGER
- Phone Number: 06-33-58-02-04
- Email: julienhuntzinger@hotmail.com
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- Patients admitted to intensive care and receiving at least one platelet transfusion in intensive care unit
Exclusion Criteria:
- Age less than 18
Study Plan
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
platelet transfusion efficacy
Time Frame: between 18 hours and 28 days after transfusion
|
corrected count platelet increment
|
between 18 hours and 28 days after transfusion
|
Collaborators and Investigators
Sponsor
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- RE-CCIP (29BRC17.0157)
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
IPD Plan Description
IPD Sharing Time Frame
IPD Sharing Access Criteria
IPD Sharing Supporting Information Type
- STUDY_PROTOCOL
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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