Acute Cycling on Executive Control (ACE)

The Effects of Acute Cycling on Executive Control

This study will examine whether 10-minute bouts of cycling at various intensities will impact executive functioning (i.e., cognitive ability) as assessed by the antisaccade (AS) task through a total of five visits. An antisaccade is a rapid eye movement away from a visual target. The ability to suppress making an eye movement towards a visual target gauges inhibitory control (i.e., a domain of executive functioning). In the initial visit, participants' exercise capacity will be assessed through a maximal effort cycling test. Intensities for the cycling bouts (i.e., high, moderate, low) in subsequent sessions will be based upon this maximal effort cycling test. In visits 2 through 5, participants will complete an AS task, followed by a 10-minute bout of cycling, and then complete the AS task again. The order of cycling intensities will be randomized between participants. Differences in the AS task (i.e., reaction time and accuracy) will be compared between and within cycling conditions.

Study Overview

• Status: Unknown
• Conditions: Physical Activity
• Intervention / Treatment: Behavioral: Sitting; Behavioral: Light-Intensity Cycling; Behavioral: Moderate-Intensity Cycling; Behavioral: High-Intensity Cycling

• Study Type: Interventional
• Enrollment (Anticipated): 20
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Harry Prapavessis, Ph.D; Phone Number: 80173 5196612111; Email: hprapave@uwo.ca
• Study Contact Backup: Name: Kirsten B Dillon, B.Sc; Phone Number: 6043566359; Email: kdillon9@uwo.ca

Study Locations

• Canada
  • Ontario
    • London, Ontario, Canada, N6A3K7
      • Western University
      • Contact: Harry Prapavessis, Ph.D

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 64 years (ADULT)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Able to read, write and understand English
• Full time student enrolled at Western University
• Able to perform a ten-minute exercise task at a light intensity without health implications
• Have email or phone number for contacting purposes

Exclusion Criteria:

• Do not have a medical condition that prevents you from exercise (e.g. heart attack in the past year, heart disease, irregular heartbeat, etc.)
• Do not have history of eye injury or neurological impairment
• Do not have an orthopaedic limitation
• Are not pregnant

Study Plan

How is the study designed?

Design Details

• Primary Purpose: BASIC_SCIENCE
• Allocation: RANDOMIZED
• Interventional Model: CROSSOVER
• Masking: NONE

Number of Arms

4

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
EXPERIMENTAL: Sitting; The participant will be asked to sit for 10 min (not increasing their heart rate) then do the anti-saccade task	Behavioral: Sitting; 10 min bouts
EXPERIMENTAL: Low-Intensity Cycling; Participant will be asked to cycle for 10 min (<40% VO2R) and then perform the anti-saccade task	Behavioral: Light-Intensity Cycling; 10min bout
EXPERIMENTAL: Moderate-Intensity Cycling; The participant will be asked to do 10 min of cycling (40-59% VO2R) followed but the anti-saccade task	Behavioral: Moderate-Intensity Cycling; 10 min bout
EXPERIMENTAL: High-Intensity Cycling; The participant will be asked to do 10 min of cycling (60%-84% VO2R) followed but the anti-saccade task	Behavioral: High-Intensity Cycling; 10 min bout

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Reaction Time	Time in milliseconds to target	30 minutes
Accuracy	Directional errors	30 minutes

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Heart Rate	Heart rate measured in beats per minute with a Polar Heart Rate Monitor as a manipulation check	10 minutes

Collaborators and Investigators

• Sponsor: Western University, Canada

Study record dates

Study Major Dates

• Study Start (ANTICIPATED): July 1, 2018
• Primary Completion (ANTICIPATED): December 31, 2018
• Study Completion (ANTICIPATED): July 31, 2019

Study Registration Dates

• First Submitted: April 9, 2018
• First Submitted That Met QC Criteria: April 9, 2018
• First Posted (ACTUAL): April 17, 2018

Study Record Updates

• Last Update Posted (ACTUAL): June 21, 2018
• Last Update Submitted That Met QC Criteria: June 19, 2018
• Last Verified: June 1, 2018

More Information

Terms related to this study

• Keywords: Physical Activity; Executive function; Anti-saccade
• Other Study ID Numbers: PA and Executive Functioning

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No