- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03850262
Traumatic Posterolateral Corner Of The Knee
Role of MRI in Traumatic Posterolateral Corner Of The Knee
The posterolateral corner (PLC) is known as the "dark side of the knee" due to its complex and variable anatomy.Its stability is provided by capsular and non-capsular structures that function as static and dynamic stabilizers.
The structures of the PLC are primarily responsible for resisting varus angulation and external tibial rotation. They also act as secondary stabilizers, in conjunction with the cruciate ligaments, to prevent anterior and posterior translation during the early phase of flexion (0°-30°) PLC injures are relatively uncommon, occurring in approximately 16% of all knee injuries. They are rarely seen in isolation, as the majority is associated with concomitant cruciate ligament tears, as well as meniscal tears and injuries to the medial ligamentous structure.
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
The mechanism of injuries is commonly result of a posterolaterally directed blow to the anteromedial aspect of the proximal tibia with the knee in full extension, other less common mechanisms include posterior rotatory dislocation (dashboard injury), anterior rotatory dislocation, and hyperextension injury with external rotation.
Early diagnosis of injuries to the posterolateral aspect of the knee is critical because surgical repair in the acute period is easier, and is associated with a more favorable outcome for patients. Also, failure to address instability of the PLC structures increases forces at anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) graft sites and may lead to failure of the cruciate reconstruction ,significant osteoarthritis and chronic knee instability Since introduction of MRI to musculoskeletal imaging in the early 1980s, it has proven to be an excellent technique for evaluating patients with knee problems. Its main advantages of MRI are its non-invasive nature and its high accuracy and negative predictive value in evaluating the menisci and ACL. Also it is useful in the detection and diagnosis of various traumatic, non traumatic knee abnormalities and diagnosis of occult or unsuspected bone lesions. It can help in the selection of those patients who need therapeutic arthroscopy.
Assessment of PLC injures is usually made clinically , including several physical examination maneuvers by orthopedic physician ; such as posterolateral drawer test, dial test, reverse pivot shift test, external rotation recurvatum test and varus stress test.
Despite these several tests, in 72% of cases they are not identified in his initial presentation, which demonstrates the difficulty of clinical diagnosis.
Thus, it is important to use additional tests for the diagnosis of posterolateral corner injury. The medical literature demonstrates that MRI has an accuracy of up to 95% for identifying major injury PLC structures, namely, lesions of the lateral collateral ligament (LCL), popliteus muscle tendon (PMT) and poplitealfibular ligament (PFL).
For better visualization of the PLC structures, an oblique coronal T2 cut should be performed. It provides an accurate and detailed evaluation of the posterolateral corner structures of the knee.
As PLC injures may be difficult to be assessed clinically because of associated and coexisting injuries at the knee, so MRI can provide vital information regarding the status of the posterolateral corner, thus enabling good surgical planning and more effective treatment.
Study Type
Enrollment (Anticipated)
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- Patients have positive tests of posterolateral corner instability by clinical examination.
- Patients who suspected by Plain X-ray to have posterolateral corner injury.
Exclusion Criteria:
- Patients whom previously underwent arthroscopy or surgically intervention to knee joint.
- Patients with history of fracture repaired by metal plates or screws.
- Patients have phobia of indoor places.
- Patients with contraindication to MRI like intra-cerebral aneurysmal clips, cardiac pacemaker, and metallic foreign body at region of examination
Study Plan
How is the study designed?
Design Details
- Observational Models: Case-Only
- Time Perspectives: Prospective
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
patients with posterolateral corner trauma of the knee
|
The study will be done on 1.5T MR unit (Siemens) and 1.5T MR unit (Philips) at Assuit University Hospital, or 1.5T MR unit (G.E.) at Eman General Hospital.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Accuracy of MRI in diagnosis of forty patients with posterolateral corner trauma of the knee.
Time Frame: one year
|
MRI at Radiological department will be done to evaluate injuries of PLC posterolateral corner of the knee in correlation with clinical or operative findings (either open or arthroscopic) as gold standard.
|
one year
|
Collaborators and Investigators
Sponsor
Publications and helpful links
General Publications
- Fornalski S, McGarry MH, Csintalan RP, Fithian DC, Lee TQ. Biomechanical and anatomical assessment after knee hyperextension injury. Am J Sports Med. 2008 Jan;36(1):80-4. doi: 10.1177/0363546507308189. Epub 2007 Oct 11.
- Baker CL Jr, Norwood LA, Hughston JC. Acute posterolateral rotatory instability of the knee. J Bone Joint Surg Am. 1983 Jun;65(5):614-8.
Study record dates
Study Major Dates
Study Start (Anticipated)
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Other Study ID Numbers
- Traumatic knee
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Traumatic Posterolateral Corner Of The Knee
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Peking University Third HospitalUnknownArthroscopy | the Posterolateral Structure of the Knee Joint | Anatomical ReconstructionChina
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Arthrex, Inc.RecruitingDegenerative and Traumatic Pathology of the Knee | Degenerative and Traumatic Pathology of the Shoulder and Elbow | Degenerative and Traumatic Pathology of the Foot and Ankle | Degenerative and Traumatic Pathology of the Hand and Wrist | Degenerative and Traumatic Pathology of the HipUnited States, United Kingdom, Canada, Puerto Rico, South Africa
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