- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04043702
Combination of Topiramate and Empagliflozin is Considered a Good Option for the Treatment of Obesity
Combination of Topiramate(Conviban) and Empagliflozin(Jardiance) is Considered a Good Option for the Treatment of Obesity
The aim was to show if a combination of topiramate and empagliflozin have the greatest weight decreasing effect in comparison to each drug alone and to group with no treatment( control group).
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Study Overview
Detailed Description
The aim was to show if a combination of topiramate and empagliflozin have the greatest weight decreasing effect in comparison to each drug alone and to group with no treatment( control group).
Materials and methods 200 obese patients 4 groups. had been monitored in a private clinic, each group 50 patients number, with 35 females and 15 males who were already on treatment.
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
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Cairo, Egypt, 11759
- Mahmoud Younis
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- stable weight in the previous 6 months.
- a sedentary lifestyle.
- no history of diabetes mellitus.
- taking medication that affects appetite, or weight within the past 6 months
Exclusion Criteria:
- severe anemia
- hypothyroidism and hyperthyroidism
- Diabetes mellitus
- moderate to severe liver or kidney disease
- body mass index less than 30
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
on topiramate
"topiramate", "conviban®" group vs no treatment ( control group).
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Intervention Other Names have not been specified
Other Names:
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on empagliflozine
"empagliflozine", "jardiance®" vs no treatment ( control group).
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Intervention Other Names have not been specified
Other Names:
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on topiramate plus empagliflozine
all patients' vs no treatment ( control group).
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Intervention Other Names have not been specified
Other Names:
|
no treatment
all patients' vs no treatment ( control group).
|
Intervention Other Names have not been specified
Other Names:
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
change in weight
Time Frame: 6 months
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weight measurement
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6 months
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Collaborators and Investigators
Investigators
- Principal Investigator: mahmoud younis, M.S, egyptian ministry of health
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 12345678
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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