- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04175652
Effects of Laughter Yoga on Hemodialysis Patients' Plasma-Beta Endorphin Levels, Pain Levels and Sleep Quality
November 21, 2019 updated by: Zülfünaz ÖZER, Istanbul Sabahattin Zaim University
Effects of Laughter Yoga on Hemodialysis Patients' Plasma-Beta Endorphin Levels, Pain Levels and Sleep Quality: A Randomized Controlled Trial
This study aimed to assess the effectiveness of laughter yoga on HD patients' plasma beta endorphin levels, pain levels and sleep quality.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
While there are studies conducted with laughter yoga on different patient groups in Turkey, no studies have been found on hemodialysis patients specifically.
For this reason, it was thought that studies are needed which will prove the effect of laughter yoga practices on the plasma beta-endorphin levels, pain levels and sleep quality of hemodialysis patients.
Study Type
Interventional
Enrollment (Actual)
68
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
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Küçükçekmece
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Istanbul, Küçükçekmece, Turkey, 34303
- Istanbul Sabahattin Zaim University, Faculty of Health Sciences
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-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 80 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- receiving treatment in a dialysis center
- must be between 18 and 80 years old and willing to participate in the study
- receiving HD treatment at least twice a week for a month or longer
- having a pain level and above
- level of 5 above according to the Pittsburgh Sleep Quality Index.
Exclusion Criteria:
- not taking any medicine for sleeping disorder
- not having any visual, hearing or communication impairments
- not having any mental disorders
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Supportive Care
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Laughter yoga group, group doing laughter yoga
The duration of the laughter yoga was 30 minutes and a total of 16 sessions were performed on a twice-weekly basis.
|
The laughter yoga practice was initiated through clapping and warm-up exercises: hands were clapped keeping hands in parallel with each other and ensuring that the fingertips touched each other.
To increase the energy level of the group, a rhythmic beat was added to the clapping in the form of 1-2, 1-2-3.
While this was being sung a rhythm was tapped out on the floor by moving the feet up and down.
Eye contact was constantly maintained with the participants.
In the second phase, deep breathing exercises were performed.
Participants were encouraged to inhale from the diaphragm.
Individuals were asked to put their hands on their belly and inhale through the nose and then slowly exhale through the mouth.
After the deep breathing exercise, the participants were encouraged to laugh through playing children's games in the third phase.
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No Intervention: No laughter yoga group, group not doing laughter yoga
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Beta-endorphin Level
Time Frame: 8 week
|
Blood samples were taken from all individuals who participated in the study, through their AVF fistulas by using 3.5 mL gel-based tubes and following antiseptic rules.
Blood samples which were fully coagulated were centrifuged at 1500xg for 10 minutes and serums were obtained.
The serum samples were separated into portions and kept at -80 °C until the analysis.
|
8 week
|
Visual Analog Scale
Time Frame: 8 week
|
The patients were asked to mark their level of pain during relaxation or activities on a 10 cm vertical or horizontal line.
In addition, there were forms which were numbered from 1-10 or from 1-100.
The number 0 is found at the beginning of the line, and the number 10 is located at the end of the line.
A value of 0 shows that there is no pain, and the value 10 expresses unendurable pain.
GAS is a common scale in the assessment of pain level.
A patient is asked to mark the perceived pain on this line, and the marked point is measured in cm
|
8 week
|
Pittsburgh Sleep Quality Index
Time Frame: 8 week
|
The PSQI is a valid and consistent survey comprising of 19 questions to assess quality and amount of sleep and the existence of a sleep disorder and its level in the previous month.
The scale was adapted into the Turkish language by Agargün et al. (1996).
The scale consists of seven components that assess patients subjective sleep quality, sleep delay, use of sleeping medication and disfunction in daily activities.
Each item scores in the range 0-3 points and the total score of the seven components gives the total PSQI score.
The total score has a value between 0-21 and a high total score demonstrates a poor quality of sleep.
A total PSQI score which is ≤5 indicates "good sleep", and a score which is >5 indicates "poor sleep"
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8 week
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Investigators
- Principal Investigator: Zülfünaz Ozer, Dr, Istanbul Sabahattin Zaim University
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Heo EH, Kim S, Park HJ, Kil SY. The effects of a simulated laughter programme on mood, cortisol levels, and health-related quality of life among haemodialysis patients. Complement Ther Clin Pract. 2016 Nov;25:1-7. doi: 10.1016/j.ctcp.2016.07.001. Epub 2016 Jul 27.
- Yim J. Therapeutic Benefits of Laughter in Mental Health: A Theoretical Review. Tohoku J Exp Med. 2016 Jul;239(3):243-9. doi: 10.1620/tjem.239.243.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
November 15, 2017
Primary Completion (Actual)
June 15, 2018
Study Completion (Actual)
October 31, 2018
Study Registration Dates
First Submitted
November 21, 2019
First Submitted That Met QC Criteria
November 21, 2019
First Posted (Actual)
November 25, 2019
Study Record Updates
Last Update Posted (Actual)
November 25, 2019
Last Update Submitted That Met QC Criteria
November 21, 2019
Last Verified
November 1, 2019
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- 2017-314
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
No
IPD Plan Description
after the article is published
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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