Association of Protein Intake With Sarcopenia Among Institutionalized Elderly

This study has purpose to investigated the association of protein intake with sarcopenia in the institutionalized elderly at south tangerang

Study Overview

• Status: Completed
• Conditions: Sarcopenia; Protein Deficiency

Detailed Description

Data were collected using interview with subjects or with care giver to know the basic characteristic of subjects. Anthropometric measurements were done body weight in kilograms was measured using SECA scale. Body height in meters was predicted by knee height measurement using knee height caliper. Body mass index (BMI) was calculated as weight per height square. Fat free mass was examined using bioelectrical impedance analyzer Tanita type SC-330. Independency was assessed using Barthel index. Protein intake was measured using 2x24 hour food recall and analyzed using a computer program Nutrisurvey 2007, data were compare to Recommended Dietary Allowances established for Indonesian 2018. Handgrip muscle strength was examined using Jamar handgrip dynamometer. Physical performance was measured using Short Physical Performance Battery test. Sarcopenia was diagnosed using Asian Working Group on Sarcopenia.

All data collected were analyzed using Statistical Package for the Social Science (SPSS) version 20 for windows. Nominal data were described using frequency, n (%). Normality of data was tested using Kolmogorov-Smirnov test with normal distribution (p>0.05) described using mean and SD while not normal distribution (p<0.05) described using median and range minimum-maximum. The investigators used Independent T-test analysis to investigate the association.

• Study Type: Observational
• Enrollment (Actual): 100

Contacts and Locations

Study Locations

• Indonesia
  • DKI Jakarta
    • Jakarta Pusat, DKI Jakarta, Indonesia, 10430
      • Fiastuti Witjaksono

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 58 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Subjects were recruited using proportional random sampling method

Description

Inclusion Criteria:

1. Inclusion criteria were being male or female
2. aged more than 60 years old
3. signed inform consent form and literate with help from companion

Exclusion Criteria:

1. subjects with history of cancer
2. history of upper and lower extremities weakness
3. history of chronic heart failure disease
4. chronic obstructive pulmonary disease

Study Plan

How is the study designed?

Design Details

• Observational Models: Other
• Time Perspectives: Cross-Sectional

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Protein intake of the subject	to assessed protein intake of the subject using 2x24 hour food recall and analyzed using a computer program Nutrisurvey 2007, data were compare to Recommended Dietary Allowances established for Indonesian 2018	After signing the consent
Distribution of sarcopenia subject in the institutionalized elderly	to investigate the distribution of sarcopenia subject using Asian Working Group Of Sarcopenia for diagnostic (fat Free Mass, handgrip strength,physical performance) Sarcopenia categorized low muscle mass (fat free mass) and either low muscular strength or low physical performance	After signing the consent
Characteristic of fat free mass subject	to examine fat free mas of the subject using bioelectrical impedance analyzer Tanita type SC-330 and classified by Asian gender and aged Male : Normal 53,30±4,79 kg Female : Normal 37,96±3,41 kg	After signing the consent
Characteristic of handgrip strength subject	to assessed handgrip strength of the subject using Jamar handgrip dynamometer, assessment criteria based on the Asian Working Group on Sarcopenia Male : Normal > 26 kg Female : > 18 kg	After signing the consent
Characteristic of physical performance subject	to examine physical performance (lower extremity strength) using Short Physical Performance Battery test. Classified using Asian Working Group on Sarcopenia Good physical performance score ≥9	After signing the consent
Association of protein intake with sarcopenia	to investigate the association of protein intake with sarcopenia. After protein intake and sarcopenia analysis were completed. The investigators used Independent T-test to analyzed the association protein intake between sarcopenia subject compare to non-sarcopenia subject	immediately after the procedure

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Nutritional status of the subjects	to investigate nutritional status using anthropometric measurements were done body weight in kilograms was measured using SECA scale. Body height in meters was predicted by knee height measurement using knee height caliper. Body mass index (BMI) was calculated as weight per height square (kg/m2). Nutritional status categorized using WHO Asia Pacific body mass index. Categorized: < 18,5 kg/m2 : underweight 18,5-22,9 kg/m2: normal 23-24,9 kg/m2: overweight >25 kg/m2: obese 1 ≥30 kg/m2 : obese 2	After signing the consent
Barthel index of the subject	to know independency of the subject using barthel index scoring Scoring: Independent : 20 Mild Dependency : 12-19 Moderate Dependency : 9-11 Severe Dependency : 5-8 Total : 0-4 Independent, n (%) Mild Dependency, n (%) Moderate Dependency, n (%) Severe Dependency, n (%)	After signing the consent

Collaborators and Investigators

• Sponsor: Indonesia University
• Investigators: Principal Investigator: Fiastuti Witjaksono, Department of Nutrition, Faculty of Medicine of Universitas Indonesia

Study record dates

Study Major Dates

• Study Start (Actual): May 20, 2019
• Primary Completion (Actual): May 30, 2019
• Study Completion (Actual): May 30, 2019

Study Registration Dates

• First Submitted: December 14, 2020
• First Submitted That Met QC Criteria: December 21, 2020
• First Posted (Actual): December 28, 2020

Study Record Updates

• Last Update Posted (Actual): December 28, 2020
• Last Update Submitted That Met QC Criteria: December 21, 2020
• Last Verified: December 1, 2020

More Information

Terms related to this study

• Keywords: Sarcopenia; Protein Intake; Institutionalized elderly
• Additional Relevant MeSH Terms: Nervous System Diseases; Neurologic Manifestations; Nutrition Disorders; Neuromuscular Manifestations; Pathological Conditions, Anatomical; Deficiency Diseases; Malnutrition; Muscular Atrophy; Atrophy; Sarcopenia; Protein Deficiency
• Other Study ID Numbers: 19-04-0421

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No