Coverage and Validity of the Swedish Registry of Cardiopulmonary Resuscitation Regarding In-hospital Cardiac Arrest

The study will have an observational retrospective cross-sectional design. Patient records and hospital administrative systems at 10 hospitals in Sweden will be searched using ICD-codes to find all patients treated for an in-hospital cardiac arrest (IHCA) during the time period of 20180101 to 20191231. All found patients will be cross-checked against reported patients in the Swedish Registry of Cardiopulmonary Resuscitation (SRCR). Any differences in patient characteristics or regarding situation factors between reported and non-reported patients will be evaluated. Non-reported patients will be retrospectively reported to the registry. An incidence of IHCA will be calculated using the number of patients treated for IHCA divided by number of hospital admissions during the specific time period. Selected variables will be evaluated regarding compliance to report and regarding concordance with patient records. All missing data will be described and evaluated. Local reporting procedures at each hospital will be described and evaluated regarding compliance to report and regarding missing data.

Study Overview

• Status: Completed
• Conditions: In-hospital Cardiac Arrest

• Study Type: Observational
• Enrollment (Actual): 1109

Contacts and Locations

Study Locations

• Sweden
  • Gothenburg, Sweden
    • Registercentrum Västra Götaland

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 4 weeks and older (Child, Adult, Older Adult)
• Accepts Healthy Volunteers: No

• Sampling Method: Probability Sample

Study Population

An in-hospital cardiac arrest is defined as an arrest that occurs in a hospitalized patient who had a pulse at the time of admission. A hospital is defined as a facility with twenty-four hours a day care including an intensive care unit and an emergency team. Treatment of a cardiac arrest involves initiation of CPR or defibrillation. Data of patients treated for in-hospital cardiac arrest will be collected from 10 hospitals of varying size during 20180101 to 20191231 in Sweden. Data of reported patients treated for in-hospital cardiac arrest during the same time period at each hospital will be extracted from the SRCR .

Description

Inclusion Criteria:

• All patients after the neonatal period that have been treated for an in-hospital cardiac arrest.

Exclusion Criteria:

• Patients with an in-hospital cardiac arrest that is not treated (do not attempt resuscitation) or patients in the neonatal period.

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
Non-reported patients treated for in-hospital cardiac arrest
Reported patients treated for in-hospital cardiac arrest

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Proportion of reported patients treated for in-hospital cardiac arrest	To evaluate the proportion of patients treated for in-hospital cardiac arrest that are reported to the SRCR	During hospital stay (retrospective observation january 1 2018 to december 31 2019)

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Incidence of in-hospital cardiac arrest	To calculate an incidence of number of patients treated for in-hospital cardiac arrest based on number of hospital admissions during a specific time period.	During hospital stay (retrospective observation january 1 2018 to december 31 2019)
Patient characteristics	To evaluate possible differences in patient characteristics or situation factors between reported and non-reported patients treated for in-hospital cardiac arrest.	During hospital stay (retrospective observation january 1 2018 to december 31 2019)

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Reporting procedures at hospitals	To describe reporting procedures at each hospital in relation to coverage of patients treated for in-hospital cardiac arrest.	At study start (interview with CPR coordinators)

Collaborators and Investigators

• Sponsor: Dalarna University
• Collaborators: Dalarna County Council, Sweden
• Investigators: Principal Investigator: Anneli Strömsöe, PhD, Dalarna University

Study record dates

Study Major Dates

• Study Start (Actual): March 10, 2022
• Primary Completion (Actual): June 12, 2023
• Study Completion (Actual): September 6, 2023

Study Registration Dates

• First Submitted: December 8, 2021
• First Submitted That Met QC Criteria: December 22, 2021
• First Posted (Actual): January 11, 2022

Study Record Updates

• Last Update Posted (Actual): September 7, 2023
• Last Update Submitted That Met QC Criteria: September 6, 2023
• Last Verified: September 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Heart Diseases; Cardiovascular Diseases; Heart Arrest
• Other Study ID Numbers: 2021-04102

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No