Interest of Catalepsy in the Hypnotic Trance (CATALHYPNOANI)

Effects of Catalepsy on the Parasympathetic Tone Assessed by ANI (Analgesia/Nociception Index) and on Absorption, Dissociation and Perception of Time During the Hypnotic Trance.

Catalepsy seems to facilitate hypnotic induction and deepen hypnotic trance, although no work confirms the usefulness of this technique which is in common use in hypnosis. Furthermore, it has been shown that the hypnotic trance state is accompanied by an increase in parasympathetic tone, the non-invasive measurement of which is easy by the ANI monitor (Analgesia Nociception Index).

The research hypothesis is that, by adding a body dissociation, catalepsy could facilitate and intensify the hypnotic trance, the intensity of which can be monitored and is proportional to the parasympathetic tone.

Study Overview

• Status: Completed
• Conditions: Hypnosis
• Intervention / Treatment: Procedure: Hypnosis session; Other: Catalepsy

Detailed Description

After randomization, subjects will either benefit from the normal hypnotic trance, or from the hypnotic trance associated with catalepsy of the hand.

T0 = installation in a sitting position and collection of an accompanying theme T1 = induction of the hypnotic trance (closing eyes) with restitution of the theme to the patient and suggestion of comfort over a period of 5 to 10 min T2 = validation of comfort by a pre-established signal T3 = return to consciousness (opening eyes) T4 = end of questionnaire about absorption, dissociation and time perception

• Study Type: Interventional
• Enrollment (Actual): 90
• Phase: Not Applicable

Contacts and Locations

Study Locations

• France
  • Rennes, France
    • Institut Emergences

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 75 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Healthy Volunteers
• Consent for participation
• Affiliation to the social security system

Exclusion Criteria:

• Arrhythmia (atrial fibrillation, pacemaker, defibrillator)
• Autonomic nervous system disorder (paraplegia, epilepsy, etc.)
• Pregnant or breastfeeding woman
• Patients under protection of the adults (guardianship, curators or safeguard of justice)
• Communication difficulties

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: hypnotic trance; Hypnosis session of comfort for 20 minutes	Procedure: Hypnosis session; Comfort hypnosis: accompaniment of a pleasant memory.
Experimental: hypnotic trance + catalepsy; Catalepsy + Hypnosis session of comfort for 20 minutes	Procedure: Hypnosis session; Comfort hypnosis: accompaniment of a pleasant memory.; Other: Catalepsy; Catalepsy of the hand.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Parasympathetic tone	Analgesia Nociception Index (ANI)	30 minutes

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Absorption	Numeric scale from 0 to 10 (0=not at all, 10=completely)	30 minutes
Dissociation	Numeric scale from 0 to 10 (0=completely in the reality, 10=completely disconnected from reality)	30 minutes
Time perception (minute)	Difference between the time of hypnosis session estimated by the patient and the actual time of hypnosis session (from closing to opening the eyes).	30 minutes
Variation of Heart Rate (beat per minute)	Heart rate measured by a pulse oximeter	30 minutes
Variation of Respiratory Rate (breath per minute)	Respiratory rate assessed by the investigator	30 minutes

Collaborators and Investigators

• Sponsor: CMC Ambroise Paré

Study record dates

Study Major Dates

• Study Start (Actual): May 26, 2022
• Primary Completion (Actual): May 28, 2022
• Study Completion (Actual): May 28, 2022

Study Registration Dates

• First Submitted: March 23, 2022
• First Submitted That Met QC Criteria: March 23, 2022
• First Posted (Actual): April 1, 2022

Study Record Updates

• Last Update Posted (Actual): June 24, 2022
• Last Update Submitted That Met QC Criteria: June 23, 2022
• Last Verified: June 1, 2022

More Information

Terms related to this study

• Keywords: Hypnosis; Absorption; Dissociation; Catalepsy; Parasympathetic tone; Perception of time
• Additional Relevant MeSH Terms: Nervous System Diseases; Neurologic Manifestations; Dyskinesias; Catalepsy
• Other Study ID Numbers: 2020/03

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No