The Effect of Curcumin Supplementation on Recovery From Exercise-induced Muscle Damage

The Effect of Curcumin Supplementation on Recovery From Exercise-induced Muscle Damage

Sponsors

Lead Sponsor: St Mary's University College

Source St Mary's University College
Brief Summary

Recent evidence suggests that curcumin supplementation may reduce muscle inflammation, oxidative markers, and muscle damage. The most favourable dosage to elicit these ergogenic effects are yet to be established; both 750mg & 1500mg has been shown to be effective. Curcumin supplementation has been ingested in numerous different ways however, no previous research to date has used curcumin in a hydrolysed (drinkable) format. The aim of this study is to investigate whether hydrolysed curcumin can reduce indices of muscle damage and improve recovery, whilst also examining a potential dose-response effect.

Overall Status Not yet recruiting
Start Date 2022-05-01
Completion Date 2023-09-30
Primary Completion Date 2022-09-30
Phase N/A
Study Type Interventional
Primary Outcome
Measure Time Frame
Blood markers Baseline
Blood markers immediately post muscle damage intervention
Blood markers 24 hours post
Blood markers 48 hours post
Blood markers 72 hours post
Ford and Fort Baseline
Ford and Fort Immediately post muscle damage intervention
Ford and Fort 24 hours post
Ford and Fort 48 hours post
Ford and Fort 72 hours post
Soreness Baseline
Soreness Immediately post muscle damage intervention
Soreness 24 hours post
Soreness 48 hours post
Soreness 72 hours post
Soreness Baseline
Soreness Immediately post muscle damage intervention
Soreness 24 hours post
Soreness 48 hours post
Soreness 72 hours post
Soreness Baseline
Soreness Immediately post muscle damage intervention
Soreness 24 hours post
Soreness 48 hours post
Soreness 72 hours post
Muscle Structure Baseline
Muscle Structure Immediately post muscle damage intervention
Muscle Structure 24 hours post
Muscle Structure 48 hours post
Muscle Structure 72 hours post
Muscle Function Baseline
Muscle Function Immediately post muscle damage intervention
Muscle Function 24 hours post
Muscle Function 48 hours post
Muscle Function 72 hours post
Muscle Function Baseline
Muscle Function Immediately post muscle damage intervention
Muscle Function 24 hours post
Muscle Function 48 hours post
Muscle Function 72 hours post
Enrollment 36
Condition
Intervention

Intervention Type: Dietary Supplement

Intervention Name: Curcumin

Description: Curcumin Supplementation

Eligibility

Criteria:

Inclusion Criteria: Inclusion criteria are as follows: - between the age of 18-35 - non-smoker - no previous history of cardiovascular, respiratory, or neurological problems - not taking anticoagulant medication - injury-free in the 3 months prior to scheduled participation in the study Exclusion Criteria: Exclusion criteria include: - hypertension (<140/80) - any blood diseases or clotting issues, - injury, or previous injury in <3 months

Gender:

All

Minimum Age:

18 Years

Maximum Age:

35 Years

Healthy Volunteers:

Accepts Healthy Volunteers

Overall Official
Overall Contact Contact information is only displayed when the study is recruiting subjects.
Verification Date

2022-04-01

Responsible Party

Type: Sponsor

Has Expanded Access No
Number Of Arms 3
Arm Group

Label: Curcumin Single

Type: Experimental

Description: The Single dose group will consume 1 placebo sachet and one curcumin sachet per day. Curcumin supplementation will be from YourZooki, the supplement in question is commercially offered to the public in a tangerine flavour. The sachets will be in 750mg hydrolysed format. The placebo is a sachet containing the same ingredients mentioned above minus the curcumin. The sachets will be in 750mg hydrolysed format. Supplementation will be administered and commence 48-hours prior to the first testing day and will be consumed twice a day (8am & 8pm).

Label: Curcumin Double

Type: Experimental

Description: The double dose group will consume two sachets per day of curcumin. Curcumin supplementation will be from YourZooki, the supplement in question is commercially offered to the public in a tangerine flavour. The sachets will be in 750mg hydrolysed format. Supplementation will be administered and commence 48-hours prior to the first testing day and will be consumed twice a day (8am & 8pm).

Label: Placebo

Type: No Intervention

Description: Placebo sachets containing the same ingredients mentioned above minus the curcumin. The sachets will be in 750mg hydrolysed format. Participants will consume two sachets per day. Supplementation will be administered and commence 48-hours prior to the first testing day and will be consumed twice a day (8am & 8pm).

Patient Data No
Study Design Info

Allocation: Randomized

Intervention Model: Parallel Assignment

Primary Purpose: Basic Science

Masking: Double (Participant, Investigator)

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact [email protected]. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Exercise Induced Muscle Damage

Clinical Trials on Curcumin