Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization

Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization: A Comprehensive Study

Molar incisor hypomineralization (MIH) can lead to many clinical conditions and affect oral health-related quality of life (OHRQoL).

Study Overview

• Status: Completed
• Conditions: Dental Caries; Pediatric ALL; Molar Incisor Hypomineralization; Dental Plaque; Child, Only; Oral Health; Dental Diseases
• Intervention / Treatment: Other: survey application

Detailed Description

Molar incisor hypomineralization (MIH) can lead to many clinical conditions and affect oral health-related quality of life (OHRQoL). The aim of this study was to determine the prevalence, etiology and impacts of MIH on oral health status and OHRQoL.

Six hundred and fifty-five parents and their children aged 9 years were included in the study. After parents completed the questionnaire about the etiology of MIH, children's OHRQoL was measured by the Child Perceptions Questionnaire (CPQ8-10). Children were evaluated for presence and severity of MIH, dental caries experience and oral hygiene status. Qualitative data were analyzed with the Pearson chi-square and Fisher's exact tests. For the quantitative data, if the normal distribution was not satisfied, Kruskal Wallis/Mann-Whitney U tests were used. Also, Binominal logistic regression analysis was performed and p<0.05 was statistical significant.

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• Study Type: Observational
• Enrollment (Actual): 655

Contacts and Locations

Study Locations

• Turkey
  • Rize, Turkey
    • Sema AYDINOGLU

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 9 years to 9 years (Child)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

9-year-old children who were enrolled in the primary schools in the city of Rize, Turkey.

Description

Inclusion Criteria:

• Being 9-year-old,
• Mentally and physically capable of completing the questionnaire,
• Presence of fully erupted 4 permanent molars and 8 permanent incisors.

Exclusion Criteria:

• Children were receiving orthodontic treatment during the examination,
• Children had enamel hypoplasia or developmental defects,
• Children had amelogenesis imperfecta or dental fluorosis.

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
To determine the prevalence and etiology of MIH.	A questionnaire was applied to the parents about the etiological factors and the prevalence of MIH was determined by oral examination.	up to four months
To evaluate the impacts of MIH on oral health status.	Oral health was evaluated by recording dmft (decayed, missing and filled teeth) and plaque index values.	up to six months
To evaluate the impacts of MIH on OHRQoL.	The impact of MIH on quality of life (OHRQoL) was measured with the Child Perception Questionnaire (CPQ8-10).	up to six months

Collaborators and Investigators

• Sponsor: Recep Tayyip Erdogan University Training and Research Hospital

Study record dates

Study Major Dates

• Study Start (Actual): February 1, 2020
• Primary Completion (Actual): April 30, 2020
• Study Completion (Actual): June 15, 2020

Study Registration Dates

• First Submitted: January 19, 2023
• First Submitted That Met QC Criteria: March 9, 2023
• First Posted (Actual): March 22, 2023

Study Record Updates

• Last Update Posted (Actual): March 22, 2023
• Last Update Submitted That Met QC Criteria: March 9, 2023
• Last Verified: March 1, 2023

More Information

Terms related to this study

• Keywords: oral health; MIH; Molar Incisor Hypomineralization; OHRQoL; Oral health related lif quality; Child Perceptions Questionnaire; CPQ
• Additional Relevant MeSH Terms: Congenital Abnormalities; Tooth Demineralization; Tooth Diseases; Stomatognathic System Abnormalities; Tooth Abnormalities; Dental Deposits; Dental Caries; Dental Enamel Hypoplasia; Dental Plaque; Stomatognathic Diseases
• Other Study ID Numbers: 140

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No