CLINICAL OUTCOME OF ENDOTRACHEAL INTUBATION IN NON-TRAUMA PATIENTS

CLINICAL OUTCOME OF ENDOTRACHEAL INTUBATION IN NON-TRAUMA PATIENTS IN THE EMERGENCY DEPARTMENT OF ALEXANDRIA MAIN UNIVERSITY HOSPITAL

The study will involve all adult patients visiting the Alexandria University main hospitals' Emergency department for reasons other than trauma that will require assisted ventilation via endotracheal intubation. Those pre-intubated or intubated post CPR will not be included. The main aim is to evaluate the clinical outcome (complications) of emergency endotracheal intubation and to correlate the incidence and nature of complications associated with tracheal intubations to demographic data and patient characteristics.

Study Overview

• Status: Completed
• Conditions: To Evaluate the Clinical Outcome (Complications) of Emergency Endotracheal Intubation in Non-traumatic Patients
• Intervention / Treatment: Device: Macintosh Laryngoscope Vs Video Laryngoscope

• Study Type: Observational
• Enrollment (Actual): 100

Contacts and Locations

Study Locations

• Egypt
  • Alexandria, Egypt
    • Alexandria University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Patients who meet the required criteria and consent to the study.

Description

Inclusion Criteria:

• Adult patients of both sex with a life threatening impairment of the cardiovascular, respiratory or neurological system requiring emergency endotracheal intubation in the emergency department of Alexandria Main University Hospital.

Exclusion Criteria:

• • Patients who are less than 18 years of age.

  • Patients intubated out of the hospital.
  • Trauma patients.
  • Patients intubated for cardiac arrest.
  • Failed intubation in the field

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Gender Based; Male patients will be compared to female patients with regards to incidence of complications	Device: Macintosh Laryngoscope Vs Video Laryngoscope; Evaluate incidence of first trial success and complications
Age Based; Various age groups will be evaluated to determine vulnerable age groups	Device: Macintosh Laryngoscope Vs Video Laryngoscope; Evaluate incidence of first trial success and complications

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Major Adverse Events	Severe hypoxemia, Cardiac arrest, Cardiovascular collapse, Death	24 hours

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Moderate Complications	Cardiac arrhythmia, Esophageal intubation, Aspiration, Dental injury, Difficulty intubation, Agitation	24 hours

Collaborators and Investigators

• Sponsor: Alexandria University

Study record dates

Study Major Dates

• Study Start (Actual): July 1, 2022
• Primary Completion (Actual): December 30, 2022
• Study Completion (Actual): December 30, 2022

Study Registration Dates

• First Submitted: March 21, 2023
• First Submitted That Met QC Criteria: March 21, 2023
• First Posted (Actual): April 3, 2023

Study Record Updates

• Last Update Posted (Actual): April 3, 2023
• Last Update Submitted That Met QC Criteria: March 21, 2023
• Last Verified: March 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pathologic Processes; Disease Attributes; Emergencies
• Other Study ID Numbers: AlexandriaU-LutherM

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No