- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05989178
Prospective Recurrent Pregnancy Loss Registry
Prospective Recurrent Pregnancy Loss (ProRPL) Registry
Study Overview
Detailed Description
The Recurrent Pregnancy Loss Program at the BC Women's Centre for Reproductive Health is the only tertiary care centre of its kind in British Columbia, and has provided specialized and comprehensive care to RPL patients for the past 15 years. Using a team-based collaborative model, the program provides point-of-care investigations, surgical treatment, clinical management, education, and grief counselling.
All RPL patients are asked to complete the intake questionnaire prior to their initial visit at the clinic. If the patient provides their consent to take part in research, their data will be copied from the clinical database to the research database. The questionnaire includes information regarding patient demographics, obstetric history, gynecological history, personal and medical history, family history and partner information. Additionally, data will also be collected from patient charts, follow-up questionnaires sent once a year for the next 5 years following the patient's initial visit, and medical records from fertility clinics and general practitioners when available.
The online data registry is housed in the Research Electronic Data Capture (REDCap) platform located at BC Children's Hospital (BCCH).
As an optional component of this study, patients invited to join the registry will also be presented with the option to register with the BCCH BioBank to store their tissue samples collected in the RPL clinic for clinical & diagnostic purposes.
Study Type
Enrollment (Estimated)
Contacts and Locations
Study Contact
- Name: Mohamed A. Bedaiwy, MD, PhD
- Phone Number: 4310 604-875-2000
- Email: mohamed.bedaiwy@cw.bc.ca
Study Locations
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British Columbia
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Vancouver, British Columbia, Canada, V6H 3N1
- Recruiting
- BC Women's Hospital & Health Centre
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Contact:
- Mohamed A. Bedaiwy, MD, PhD
- Phone Number: 4310 604-875-2000
- Email: mohamed.bedaiwy@cw.bc.ca
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-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
Inclusion Criteria:
• All new and re-referred patients at the BC Women's Recurrent Pregnancy Loss Clinic with recurrent pregnancy loss, defined as ≥2 miscarriages or ≥1 miscarriage beyond 10 weeks gestation; therapeutic abortions, ectopic pregnancies, and molar pregnancies are excluded from the miscarriage count.
Exclusion Criteria:
• Patients at BC Women's Recurrent Pregnancy Loss Clinic seen for reasons other than recurrent pregnancy loss.
Study Plan
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Live Birth
Time Frame: 5 years
|
Percent of patients with a live birth within 5 years after initial visit at the clinic.
|
5 years
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Mohamed A. Bedaiwy, MD, PhD, BC Women's Hospital & Health Centre
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- H21-01887
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Recurrent Pregnancy Loss
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University Hospital, ToulouseCompleted
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Wake Forest University Health SciencesWithdrawnRecurrent Pregnancy Loss Without Current Pregnancy
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Bagcilar Training and Research HospitalCompletedRecurrent Pregnancy Loss Without Current PregnancyTurkey
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Caroline Nørgaard-PedersenDepartment of Clinical Immunology, Odense University Hospital, DK; Department...RecruitingRecurrent Pregnancy Loss, Not PregnantDenmark
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Mỹ Đức HospitalNot yet recruitingVaginal Microbiome | Recurrent Pregnancy Loss, Not Pregnant
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Nora Therapeutics, Inc.UnknownRecurrent Miscarriage | Recurrent Pregnancy LossUnited Kingdom
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Soroka University Medical CenterUnknownRecurrent Miscarriage | Recurrent Pregnancy Loss(RPL)Israel
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Peking University Third HospitalCompletedRecurrent Early Pregnancy LossChina
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Ain Shams UniversityCompletedRecurrent Pregnancy LossEgypt
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Institute of Biophysics and Cell Engineering of...Belarusian Medical Academy of Post-Graduate EducationNot yet recruiting
Clinical Trials on Data Registry
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Sunnybrook Health Sciences CentreNot yet recruitingPregnancy Related | Fetal Growth Retardation | Preeclampsia | Cervix; Pregnancy | Placental Insufficiency
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