Effects of Transcranial Oscillatory Direct Current Stimulation on the Functions of Cerebral Cortex in Healthy Subjects

February 22, 2024 updated by: Yuan Xing, The First Hospital of Hebei Medical University
To investigate the effect of transcranial oscillatory direct current stimulation on functions of cerebral cortex (cortical excitability and frequency of eeg) in healthy subjects

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

15

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

  • Name: Nan Zhang, PhD, MD
  • Phone Number: +8618633888974
  • Email: jlx88cn@163.com

Study Locations

  • China
    • Hebei
      • Shijiazhuang, Hebei, China, 050031
        • Recruiting
        • The First Hospital of Hebei Medical University
        • Contact:
        • Contact:
        • Principal Investigator:
          • Yuan Xing, PhD, MD
        • Sub-Investigator:
          • Nan Zhang, PhD, MD
        • Sub-Investigator:
          • Shujuan Tian, PhD, MD
        • Sub-Investigator:
          • Xian Tan

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Healthy male
  • Age ranges from 20 to 30 years old
  • No history of neurological or psychiatric diseases, no history of chronic illness
  • No positive results were found in the examination of the nervous system
  • All right-handed according to Edinburgh Handedness Inventory
  • The subjects voluntarily participated in this study and signed an informed consent form

Exclusion Criteria:

  • Individuals with severe illnesses
  • Previous history of brain surgery or epilepsy
  • Individuals who experience changes in physical condition during the experiment
  • Individuals with metal implants, such as pacemakers, DBS therapists, stents, etc
  • Alcoholics

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: healthy subjects
healthy male subjects aged 20-30 years
Device: toDCS 2mA 1Hz
The subgroup treated by transcranial oscillatory direct current stimulation of 2mA and 1Hz.
Device: toDCS 2mA 10Hz
The subgroup treated by transcranial oscillatory direct current stimulation of 2mA and 10Hz.
Device: tDCS 1mA
The subgroup treated by transcranial direct current stimulation of 1mA.
Device: sham
The subgroup treated by sham stimulation.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
MEP
Time Frame: before treatment and 20, 30, 40, 50, 60 minutes after treatment
Motor evoked potentials of the right abductor pollicis brevis were collected
before treatment and 20, 30, 40, 50, 60 minutes after treatment
Power Spectral Density of EEG
Time Frame: before treatment and right after treatment
The rest state EEG of the subjects was collected
before treatment and right after treatment

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

The First Hospital of Hebei Medical University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 1, 2023

Primary Completion (Actual)

November 30, 2023

Study Completion (Estimated)

March 15, 2024

Study Registration Dates

First Submitted

September 21, 2023

First Submitted That Met QC Criteria

October 7, 2023

First Posted (Actual)

October 10, 2023

Study Record Updates

Last Update Posted (Actual)

February 23, 2024

Last Update Submitted That Met QC Criteria

February 22, 2024

Last Verified

February 1, 2024

More Information

Terms related to this study

Other Study ID Numbers

  • FirstHebei

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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