The Effect of Dexmedetomidine on Kidney Function in EVAR
The Effect of Dexmedetomidine on the Incidence of Acute Kidney Injury in EVAR
Patrocinadores |
Patrocinador principal: University of Thessaly |
||||||||
---|---|---|---|---|---|---|---|---|---|
Fuente | University of Thessaly | ||||||||
Resumen breve | This study will investigate the effect of dexmedetomidine on the incidence of postoperative acute kidney injury in patients undergoing EVAR under general anesthesia |
||||||||
Descripción detallada | This study will compare the incidence of AKI after elective EVAR conducted under general anesthesia with and without administration of dexmedetomidine. The AKI will be evaluated through measuring NGAL and c-cystatin. |
||||||||
Estado general | Not yet recruiting | ||||||||
Fecha de inicio | March 30, 2021 | ||||||||
Fecha de Terminación | February 1, 2024 | ||||||||
Fecha de finalización primaria | November 30, 2023 | ||||||||
Fase | N/A | ||||||||
Tipo de estudio | Interventional | ||||||||
Resultado primario |
|
||||||||
Resultado secundario |
|
||||||||
Inscripción | 200 | ||||||||
Condición | |||||||||
Intervención |
Tipo de intervención: Drug Nombre de intervención: Dexmedetomidine Descripción: Administration of dexmedetomidine intraoperatively Etiqueta de grupo de brazo: DEXMEDETOMIDINE AND AKI |
||||||||
Elegibilidad |
Criterios:
Inclusion Criteria: - elective EVAR under general anesthesia - adult patients 18- 85 years old - American society of anesthesiologists (ASA) physical status I - IV Exclusion Criteria: - refusal to participate or sign the informed consent form - GFR < 50ml/mim - Bradyarrhythmia <50/min - Hemodynamic instability - Known allergy to Dexmedetomidine - Severe hepatic insufficiency Género: All Edad mínima: 18 Years Edad máxima: 85 Years Voluntarios Saludables: No |
||||||||
Oficial general |
|
||||||||
Contacto general |
Apellido: Eleni Arnaoutoglou, MD, PhD Teléfono: +306974301352 Email: [email protected] |
||||||||
Ubicación |
|
||||||||
Ubicacion Paises |
Greece |
||||||||
Fecha de verificación |
February 2021 |
||||||||
Fiesta responsable |
Tipo: Principal Investigator Afiliación del investigador: University of Thessaly Nombre completo del investigador: Elena Arnaoutoglou Título del investigador: Professor of anesthesiology |
||||||||
Palabras clave | |||||||||
Tiene acceso ampliado | No | ||||||||
Condición Examinar | |||||||||
Número de brazos | 2 | ||||||||
Grupo de brazo |
Etiqueta: DEXMEDETOMIDINE AND AKI Tipo: Active Comparator Descripción: The patients of the group undergoing EVAR under general anesthesia will receive dexmedetomidine intraoperatively. Etiqueta: CONTROL AND AKI Tipo: No Intervention Descripción: The patients of the group undergoing EVAR under general anesthesia will not receive dexmedetomidine intraoperatively. |
||||||||
Acrónimo | DEVAR | ||||||||
Datos del paciente | No | ||||||||
Información de diseño del estudio |
Asignación: Randomized Modelo de intervención: Parallel Assignment Propósito primario: Prevention Enmascaramiento: Triple (Participant, Investigator, Outcomes Assessor) |