The Effect of Dexmedetomidine on Kidney Function in EVAR
The Effect of Dexmedetomidine on the Incidence of Acute Kidney Injury in EVAR
| Patrocinadores |
Patrocinador principal: University of Thessaly |
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| Fuente | University of Thessaly | ||||||||
| Resumen breve | This study will investigate the effect of dexmedetomidine on the incidence of postoperative acute kidney injury in patients undergoing EVAR under general anesthesia |
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| Descripción detallada | This study will compare the incidence of AKI after elective EVAR conducted under general anesthesia with and without administration of dexmedetomidine. The AKI will be evaluated through measuring NGAL and c-cystatin. |
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| Estado general | Not yet recruiting | ||||||||
| Fecha de inicio | March 30, 2021 | ||||||||
| Fecha de Terminación | February 1, 2024 | ||||||||
| Fecha de finalización primaria | November 30, 2023 | ||||||||
| Fase | N/A | ||||||||
| Tipo de estudio | Interventional | ||||||||
| Resultado primario |
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| Resultado secundario |
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| Inscripción | 200 | ||||||||
| Condición | |||||||||
| Intervención |
Tipo de intervención: Drug Nombre de intervención: Dexmedetomidine Descripción: Administration of dexmedetomidine intraoperatively Etiqueta de grupo de brazo: DEXMEDETOMIDINE AND AKI |
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| Elegibilidad |
Criterios:
Inclusion Criteria: - elective EVAR under general anesthesia - adult patients 18- 85 years old - American society of anesthesiologists (ASA) physical status I - IV Exclusion Criteria: - refusal to participate or sign the informed consent form - GFR < 50ml/mim - Bradyarrhythmia <50/min - Hemodynamic instability - Known allergy to Dexmedetomidine - Severe hepatic insufficiency Género: All Edad mínima: 18 Years Edad máxima: 85 Years Voluntarios Saludables: No |
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| Oficial general |
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| Contacto general |
Apellido: Eleni Arnaoutoglou, MD, PhD Teléfono: +306974301352 Email: [email protected] |
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| Ubicación |
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| Ubicacion Paises |
Greece |
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| Fecha de verificación |
February 2021 |
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| Fiesta responsable |
Tipo: Principal Investigator Afiliación del investigador: University of Thessaly Nombre completo del investigador: Elena Arnaoutoglou Título del investigador: Professor of anesthesiology |
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| Palabras clave | |||||||||
| Tiene acceso ampliado | No | ||||||||
| Condición Examinar | |||||||||
| Número de brazos | 2 | ||||||||
| Grupo de brazo |
Etiqueta: DEXMEDETOMIDINE AND AKI Tipo: Active Comparator Descripción: The patients of the group undergoing EVAR under general anesthesia will receive dexmedetomidine intraoperatively. Etiqueta: CONTROL AND AKI Tipo: No Intervention Descripción: The patients of the group undergoing EVAR under general anesthesia will not receive dexmedetomidine intraoperatively. |
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| Acrónimo | DEVAR | ||||||||
| Datos del paciente | No | ||||||||
| Información de diseño del estudio |
Asignación: Randomized Modelo de intervención: Parallel Assignment Propósito primario: Prevention Enmascaramiento: Triple (Participant, Investigator, Outcomes Assessor) |
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