德国中风登记处 - 血管内治疗 (GSR-ET)
2022年12月28日 更新者：Universitätsklinikum Hamburg-Eppendorf
德国中风注册 (GSR) 血管内治疗是一项学术性、独立、前瞻性、多中心、观察性注册研究。
接受血管内卒中治疗的连续患者将被纳入德国卒中中心。
患者接受定期护理，数据将作为临床常规的一部分进行收集。
收集基线临床和程序信息以及住院期间的临床随访信息，直至中风发作 90 天。
收集的数据包括人口统计学、入院时美国国立卫生研究院卒中量表 (NIHSS)、治疗前 ASPECTS、介入治疗的时间和成功信息、手术并发症、颅内出血和功能结果。
研究概览
研究类型
观察性的
注册 (预期的)
10000
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习联系方式
- 姓名：Maximilian Schell
- 电话号码：+49 (0)1522/2834807
- 邮箱：m.schell@uke.de
研究联系人备份
- 姓名：Götz Thomalla, Prof. Dr. med.
- 电话号码：+49 (0)40/7410-0
- 邮箱：thomalla@uke.de
学习地点
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-
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Hamburg、德国、20251
- 招聘中
- University Medical Center Hamburg-Eppendorf (UKE)
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接触：
- Maximilian Schell
- 电话号码：+49 (0)1522/2834807
- 邮箱：m.schell@uke.de
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接触：
- Götz Thomalla, Prof. Dr. med.
- 电话号码：+49 (0)40/7410-0
- 邮箱：thomalla@uke.de
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首席研究员：
- Christian Gerloff, Prof. Dr. med.
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参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
18年 及以上 (成人、年长者)
接受健康志愿者
不
有资格学习的性别
全部
取样方法
概率样本
研究人群
所有临床诊断为急性缺血性卒中的急性卒中患者，符合 IVT 且在卒中发作后 4.5 小时内开始 IVT，年龄 >18 岁
描述
纳入标准：
- 急性缺血性脑卒中的临床诊断
- 有资格接受静脉溶栓 (IVT) 和中风发作后 4.5 小时内开始的 IVT
- 颈总动脉、大脑中动脉（M1 或 M2）或基底动脉持续闭塞的确诊诊断与症状一致
- 年龄 >18 岁
- 正在进行伦理审批
排除标准：无
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 观测模型：队列
- 时间观点：预期
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
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中风病人
联合或不联合血管内治疗的急性脑卒中患者
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第 90 天电话评估主要结果 (mRs d90)
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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第 90 天的改良等级量表 (mRS)
大体时间：90天
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该量表是中风患者日常活动中的残疾或依赖程度的常用衡量标准； 刻度范围0-6； 0 - 没有症状。 1 - 无重大残疾。 能够进行所有日常活动，尽管有一些症状。 2 - 轻微残疾。 能够独立处理自己的事务，但无法进行之前的所有活动。 3 - 中度残疾。 需要一些帮助，但能够独立行走。 4 - 中度严重残疾。 在没有帮助的情况下无法满足自己的身体需求，并且无法独立行走。 5 - 严重残疾。 需要持续的护理和照顾，卧床不起，大小便失禁。 6 - 死了。 出版物：van Swieten J、Koudstaal P、Visser M、Schouten H 等。 （1988）。 “中风患者残疾评估的观察者间协议”。 中风。 19 (5): 604-607。 内政部：10.1161/01.str.19.5.604。 PMID 3363593。 |
90天
|
合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
合作者
调查人员
- 首席研究员：Martin Dichgans, Prof. Dr. med.、LMU, Munich, Germany
- 首席研究员：Christian Gerloff, Prof. Dr. med.、UKE, Hamburg, Germany
出版物和有用的链接
负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。
一般刊物
- Kellert L, Wollenweber FA, Thomalla G, Nolte CH, Fiehler J, Ringleb PA, Dorn F. Thrombolysis management in thrombectomy patients: Real-life data from German stroke centres. Eur Stroke J. 2017 Dec;2(4):356-360. doi: 10.1177/2396987317727229. Epub 2017 Aug 17.
- Alegiani AC, Dorn F, Herzberg M, Wollenweber FA, Kellert L, Siebert E, Nolte CH, von Rennenberg R, Hattingen E, Petzold GC, Bode FJ, Pfeilschifter W, Schafer JH, Wagner M, Rother J, Eckert B, Kraft P, Pham M, Boeckh-Behrens T, Wunderlich S, Bernkopf K, Reich A, Wiesmann M, Mpotsaris A, Psychogios M, Liman J, Maier I, Berrouschot J, Bormann A, Limmroth V, Spreer J, Petersen M, Krause L, Lowens S, Kraemer C, Zweynert S, Lange KS, Thonke S, Kastrup A, Papanagiotou P, Alber B, Braun M, Fiehler J, Gerloff C, Dichgans M, Thomalla G. Systematic evaluation of stroke thrombectomy in clinical practice: The German Stroke Registry Endovascular Treatment. Int J Stroke. 2019 Jun;14(4):372-380. doi: 10.1177/1747493018806199. Epub 2018 Oct 22. Erratum In: Int J Stroke. 2018 Dec 17;:1747493018816194. Eur J Prev Cardiol. 2020 Nov;27(17):NP16.
- Wollenweber FA, Tiedt S, Alegiani A, Alber B, Bangard C, Berrouschot J, Bode FJ, Boeckh-Behrens T, Bohner G, Bormann A, Braun M, Dorn F, Eckert B, Flottmann F, Hamann GF, Henn KH, Herzberg M, Kastrup A, Kellert L, Kraemer C, Krause L, Lehm M, Liman J, Lowens S, Mpotsaris A, Papanagiotou P, Petersen M, Petzold GC, Pfeilschifter W, Psychogios MN, Reich A, von Rennenberg R, Rother J, Schafer JH, Siebert E, Siedow A, Solymosi L, Thonke S, Wagner M, Wunderlich S, Zweynert S, Nolte CH, Gerloff C, Thomalla G, Dichgans M, Fiehler J. Functional Outcome Following Stroke Thrombectomy in Clinical Practice. Stroke. 2019 Sep;50(9):2500-2506. doi: 10.1161/STROKEAHA.119.026005. Epub 2019 Jul 24.
- Tiedt S, Herzberg M, Kupper C, Feil K, Kellert L, Dorn F, Liebig T, Alegiani A, Dichgans M, Wollenweber FA; GSR Investigators. Stroke Etiology Modifies the Effect of Endovascular Treatment in Acute Stroke. Stroke. 2020 Mar;51(3):1014-1016. doi: 10.1161/STROKEAHA.119.028383. Epub 2019 Dec 18.
- Meyer L, Alexandrou M, Flottmann F, Deb-Chatterji M, Abdullayev N, Maus V, Politi M, Bernkopf K, Roth C, Kastrup A, Hanning U, Brekenfeld C, Thomalla G, Gerloff C, Mpotsaris A, Papanagiotou P, Fiehler J, Leischner H; German Stroke Registry-Endovascular Treatment (GSR-ET) dagger. Endovascular Treatment of Very Elderly Patients Aged >/=90 With Acute Ischemic Stroke. J Am Heart Assoc. 2020 Mar 3;9(5):e014447. doi: 10.1161/JAHA.119.014447. Epub 2020 Feb 24.
- Meyer L, Broocks G, Bechstein M, Flottmann F, Leischner H, Brekenfeld C, Schon G, Deb-Chatterji M, Alegiani A, Thomalla G, Fiehler J, Kniep H, Hanning U; German Stroke Registry - Endovascular Treatment (GSR - ET). Early clinical surrogates for outcome prediction after stroke thrombectomy in daily clinical practice. J Neurol Neurosurg Psychiatry. 2020 Oct;91(10):1055-1059. doi: 10.1136/jnnp-2020-323742.
- Deb-Chatterji M, Pinnschmidt H, Flottmann F, Leischner H, Broocks G, Alegiani A, Brekenfeld C, Fiehler J, Gerloff C, Thomalla G; GSR-ET Investigators. Predictors of independent outcome of thrombectomy in stroke patients with large baseline infarcts in clinical practice: a multicenter analysis. J Neurointerv Surg. 2020 Nov;12(11):1064-1068. doi: 10.1136/neurintsurg-2019-015641. Epub 2020 Feb 27.
- Tiedt S, Bode FJ, Uphaus T, Alegiani A, Groschel K, Petzold GC; GSR-ET investigators. Impact of the COVID-19-pandemic on thrombectomy services in Germany. Neurol Res Pract. 2020 Nov 23;2:44. doi: 10.1186/s42466-020-00090-0. eCollection 2020.
- Flottmann F, Brekenfeld C, Broocks G, Leischner H, McDonough R, Faizy TD, Deb-Chatterji M, Alegiani A, Thomalla G, Mpotsaris A, Nolte CH, Fiehler J, Maros ME; GSR investigators*. Good Clinical Outcome Decreases With Number of Retrieval Attempts in Stroke Thrombectomy: Beyond the First-Pass Effect. Stroke. 2021 Jan;52(2):482-490. doi: 10.1161/STROKEAHA.120.029830. Epub 2021 Jan 20. Erratum In: Stroke. 2021 Apr;52(4):e116.
- Feil K, Herzberg M, Dorn F, Tiedt S, Kupper C, Thunstedt DC, Hinske LC, Muhlbauer K, Goss S, Liebig T, Dieterich M, Bayer A, Kellert L; GSR Investigators. General Anesthesia versus Conscious Sedation in Mechanical Thrombectomy. J Stroke. 2021 Jan;23(1):103-112. doi: 10.5853/jos.2020.02404. Epub 2021 Jan 31.
- Feil K, Kupper C, Tiedt S, Dimitriadis K, Herzberg M, Dorn F, Liebig T, Dieterich M, Kellert L; GSR Investigators. Safety and efficacy of mechanical thrombectomy in infective endocarditis: A matched case-control analysis from the German Stroke Registry-Endovascular Treatment. Eur J Neurol. 2021 Mar;28(3):861-867. doi: 10.1111/ene.14686. Epub 2021 Jan 6.
- Flottmann F, Broocks G, Faizy TD, McDonough R, Watermann L, Deb-Chatterji M, Thomalla G, Herzberg M, Nolte CH, Fiehler J, Leischner H, Brekenfeld C; GSR investigators. Factors Associated with Failure of Reperfusion in Endovascular Therapy for Acute Ischemic Stroke : A Multicenter Analysis. Clin Neuroradiol. 2021 Mar;31(1):197-205. doi: 10.1007/s00062-020-00880-8. Epub 2020 Feb 17.
- Feil K, Herzberg M, Dorn F, Tiedt S, Kupper C, Thunstedt DC, Papanagiotou P, Meyer L, Kastrup A, Dimitriadis K, Liebig T, Dieterich M, Kellert L; GSR investigatorsdagger. Tandem Lesions in Anterior Circulation Stroke: Analysis of the German Stroke Registry-Endovascular Treatment. Stroke. 2021 Apr;52(4):1265-1275. doi: 10.1161/STROKEAHA.120.031797. Epub 2021 Feb 16.
- Schlemm L, von Rennenberg R, Siebert E, Bohner G, Flottmann F, Petzold GC, Thomalla G, Endres M, Nolte CH; GSR-ET investigators. Mechanical thrombectomy in patients with cervical artery dissection and stroke in the anterior or posterior circulation - a multicenter analysis from the German Stroke Registry. Neurol Res Pract. 2021 May 3;3(1):20. doi: 10.1186/s42466-021-00119-y.
- Kupper C, Feil K, Wollenweber FA, Tiedt S, Herzberg M, Dorn F, Liebig T, Dieterich M, Kellert L; GSR investigators. Endovascular stroke treatment in orally anticoagulated patients: an analysis from the German Stroke Registry-Endovascular Treatment. J Neurol. 2021 May;268(5):1762-1769. doi: 10.1007/s00415-020-10369-6. Epub 2020 Dec 29.
- Maros ME, Brekenfeld C, Broocks G, Leischner H, McDonough R, Deb-Chatterji M, Alegiani A, Thomalla G, Fiehler J, Flottmann F; GSR Investigators*. Number of Retrieval Attempts Rather Than Procedure Time Is Associated With Risk of Symptomatic Intracranial Hemorrhage. Stroke. 2021 May;52(5):1580-1588. doi: 10.1161/STROKEAHA.120.031242. Epub 2021 Apr 5.
- Herzberg M, Scherling K, Stahl R, Tiedt S, Wollenweber FA, Kupper C, Feil K, Forbrig R, Patzig M, Kellert L, Kunz WG, Reidler P, Zimmermann H, Liebig T, Dieterich M, Dorn F; GSR investigators. Late Thrombectomy in Clinical Practice : Retrospective Application of DAWN/DEFUSE3 Criteria within the German Stroke Registry. Clin Neuroradiol. 2021 Sep;31(3):799-810. doi: 10.1007/s00062-021-01033-1. Epub 2021 Jun 7.
- Weller JM, Enkirch SJ, Bogs C, Braemswig TB, Deb-Chatterji M, Keil F, Kindler C, Maywald S, Schirmer MD, Stosser S, Solymosi L, Nolte CH, Bode FJ, Petzold GC; GSR-ET Investigators. Endovascular Treatment for Acute Stroke in Cerebral Amyloid Angiopathy. Stroke. 2021 Oct;52(10):e581-e585. doi: 10.1161/STROKEAHA.120.033014. Epub 2021 Aug 20.
- Meyer L, Bechstein M, Bester M, Hanning U, Brekenfeld C, Flottmann F, Kniep H, van Horn N, Deb-Chatterji M, Thomalla G, Sporns P, Yeo LL, Tan BY, Gopinathan A, Kastrup A, Politi M, Papanagiotou P, Kemmling A, Fiehler J, Broocks G; German Stroke Registry-Endovascular Treatment (GSR-ET). Thrombectomy in Extensive Stroke May Not Be Beneficial and Is Associated With Increased Risk for Hemorrhage. Stroke. 2021 Oct;52(10):3109-3117. doi: 10.1161/STROKEAHA.120.033101. Epub 2021 Sep 2.
- Leischner H, Brekenfeld C, Meyer L, Broocks G, Faizy T, McDonough R, Gerloff C, Thomalla G, Deb-Chatterji M, Fiehler J, Flottmann F; German Stroke Registry - Endovascular treatment (GSR) *. Study Criteria Applied to Real Life-A Multicenter Analysis of Stroke Patients Undergoing Endovascular Treatment in Clinical Practice. J Am Heart Assoc. 2021 Nov 16;10(22):e017919. doi: 10.1161/JAHA.120.017919. Epub 2021 Nov 15.
- Deb-Chatterji M, Schlemm E, Flottmann F, Meyer L, Alegiani A, Brekenfeld C, Fiehler J, Gerloff C, Thomalla G; GSR-ET Investigators. Sex Differences in Outcome After Thrombectomy for Acute Ischemic Stroke are Explained by Confounding Factors. Clin Neuroradiol. 2021 Dec;31(4):1101-1109. doi: 10.1007/s00062-020-00983-2. Epub 2020 Dec 21.
- Stosser S, Bode FJ, Dorn F, Petzold GC; GSR-ET Study Group. Workflow Times and Outcome of Endovascular Therapy in Stroke Patients with Initial MRI or CT. Cerebrovasc Dis. 2022;51(1):45-51. doi: 10.1159/000517903. Epub 2021 Jul 30.
- Broocks G, McDonough R, Bechstein M, Hanning U, Brekenfeld C, Flottmann F, Kniep H, Nawka MT, Deb-Chatterji M, Thomalla G, Sporns P, Yeo LL, Tan BY, Gopinathan A, Kastrup A, Politi M, Papanagiotou P, Kemmling A, Fiehler J, Meyer L; German Stroke Registry - Endovascular Treatment (GSR-ET). Benefit and risk of intravenous alteplase in patients with acute large vessel occlusion stroke and low ASPECTS. J Neurointerv Surg. 2023 Jan;15(1):8-13. doi: 10.1136/neurintsurg-2021-017986. Epub 2022 Jan 25.
- Hahn M, Groschel S, Tanyildizi Y, Brockmann MA, Groschel K, Uphaus T; German Stroke Registry-Endovascular Treatment (GSR-ET) Investigators. The Bigger the Better? Center Volume Dependent Effects on Procedural and Functional Outcome in Established Endovascular Stroke Centers. Front Neurol. 2022 Mar 2;13:828528. doi: 10.3389/fneur.2022.828528. eCollection 2022.
- Feil K, Matusevicius M, Herzberg M, Tiedt S, Kupper C, Wischmann J, Schonecker S, Mengel A, Sartor-Pfeiffer J, Berger K, Dimitriadis K, Liebig T, Dieterich M, Mazya M, Ahmed N, Kellert L. Minor stroke in large vessel occlusion: A matched analysis of patients from the German Stroke Registry-Endovascular Treatment (GSR-ET) and patients from the Safe Implementation of Treatments in Stroke-International Stroke Thrombolysis Register (SITS-ISTR). Eur J Neurol. 2022 Jun;29(6):1619-1629. doi: 10.1111/ene.15272. Epub 2022 Feb 19.
- Quandt F, Flottmann F, Madai VI, Alegiani A, Kupper C, Kellert L, Hilbert A, Frey D, Liebig T, Fiehler J, Goyal M, Saver JL, Gerloff C, Thomalla G, Tiedt S; GSR investigators and the VISTA-Endovascular Collaborators. Machine Learning-Based Identification of Target Groups for Thrombectomy in Acute Stroke. Transl Stroke Res. 2022 Jun 7. doi: 10.1007/s12975-022-01040-5. Online ahead of print.
- Flottmann F, van Horn N, Maros ME, Leischner H, Bechstein M, Meyer L, Sauer M, Deb-Chatterji M, Alegiani A, Thomalla G, Fiehler J, Brekenfeld C; GSR investigators. More Retrieval Attempts are Associated with Poorer Functional Outcome After Unsuccessful Thrombectomy. Clin Neuroradiol. 2022 Jun;32(2):361-368. doi: 10.1007/s00062-021-01054-w. Epub 2021 Jul 8.
- Flottmann F, van Horn N, Maros ME, McDonough R, Deb-Chatterji M, Alegiani A, Thomalla G, Hanning U, Fiehler J, Brekenfeld C; GSR investigators. Early TICI 2b or Late TICI 3-Is Perfect the Enemy of Good? Clin Neuroradiol. 2022 Jun;32(2):353-360. doi: 10.1007/s00062-021-01048-8. Epub 2021 Jun 30.
- Burian E, Sepp D, Lehm M, Bernkopf K, Wunderlich S, Riederer I, Maegerlein C, Alegiani A, Zimmer C, Boeckh-Behrens T; GSR-ET Investigators. Start, Stop, Continue? The Benefit of Overlapping Intravenous Thrombolysis and Mechanical Thrombectomy : A Matched Case-control Analysis from the German Stroke Registry. Clin Neuroradiol. 2022 Jul 26. doi: 10.1007/s00062-022-01200-y. Online ahead of print.
- Stosser S, Bode FJ, Meissner JN, Weller JM, Kindler C, Sauer M, Paech D, Riegler C, Nolte CH, Pourian A, Rother J, Selo N, Ernemann U, Poli S, Eckert RM, Bohner G, Scherling K, Dorn F, Petzold GC; GSR-ET study group. Outcome of Stroke Patients with Unknown Onset and Unknown Time Last Known Well Undergoing Endovascular Therapy. Clin Neuroradiol. 2022 Jul 7. doi: 10.1007/s00062-022-01188-5. Online ahead of print.
- Meyer L, Politi M, Alexandrou M, Roth C, Kastrup A, Mpotsaris A, Hanning U, Flottmann F, Brekenfeld C, Deb-Chatterji M, Thomalla G, Kniep H, Faizy TD, Bechstein M, Broocks G, Herzberg M, Feil K, Kellert L, Dorn F, Zelenak K, Fiehler J, Papanagiotou P; German Stroke Registry-Endovascular Treatment (GSR-ET); German Stroke Registry - Endovascular Treatment (GSR - ET). Endovascular treatment of acute tandem lesions in patients with mild anterior circulation stroke. J Neurointerv Surg. 2022 Aug 26:neurintsurg-2022-019239. doi: 10.1136/jnis-2022-019239. Online ahead of print.
- Hahn M, Groschel S, Hayani E, Brockmann MA, Muthuraman M, Groschel K, Uphaus T; German Stroke Registry-Endovascular Treatment (GSR-ET) Study Group. Sex Disparities in Re-Employment in Stroke Patients With Large Vessel Occlusion Undergoing Mechanical Thrombectomy. Stroke. 2022 Aug;53(8):2528-2537. doi: 10.1161/STROKEAHA.121.037386. Epub 2022 Apr 21.
- Schaefer JH, Kurka N, Keil F, Wagner M, Steinmetz H, Pfeilschifter W, Bohmann FO. Endovascular treatment for ischemic stroke with the drip-and-ship model-Insights from the German Stroke Registry. Front Neurol. 2022 Aug 23;13:973095. doi: 10.3389/fneur.2022.973095. eCollection 2022.
- Weller JM, Meissner JN, Stosser S, Dorn F, Petzold GC, Bode FJ; GSR-ET investigators. Mechanical Thrombectomy in Patients with Acute Ischemic Stroke and Concomitant Intracranial Hemorrhage. Clin Neuroradiol. 2022 Sep;32(3):809-816. doi: 10.1007/s00062-021-01128-9. Epub 2022 Jan 6.
- Weller JM, Dorn F, Meissner JN, Stosser S, Beckonert NM, Nordsiek J, Kindler C, Deb-Chatterji M, Petzold GC, Bode FJ; GSR-ET investigators. Endovascular thrombectomy in young patients with stroke. Int J Stroke. 2022 Sep 7:17474930221119602. doi: 10.1177/17474930221119602. Online ahead of print.
- Weller JM, Dorn F, Meissner JN, Stosser S, Beckonert NM, Nordsiek J, Kindler C, Riegler C, Keil F, Petzold GC, Bode FJ; GSR-ET investigators. Antithrombotic treatment and outcome after endovascular treatment and acute carotid artery stenting in stroke patients with atrial fibrillation. Neurol Res Pract. 2022 Sep 12;4(1):42. doi: 10.1186/s42466-022-00207-7.
- Kniep H, Meyer L, Bechstein M, Broocks G, Guerreiro H, van Horn N, Brekenfeld C, Flottmann F, Deb-Chatterji M, Alegiani A, Thomalla G, Hanning U, Fiehler J, Gellissen S; GSR-ET (German Stroke Registry-Endovascular Treatment). How Much of the Thrombectomy Related Improvement in Functional Outcome Is Already Apparent at 24 Hours and at Hospital Discharge? Stroke. 2022 Sep;53(9):2828-2837. doi: 10.1161/STROKEAHA.121.037888. Epub 2022 May 13.
- Broocks G, Hanning U, Bechstein M, Elsayed S, Faizy TD, Brekenfeld C, Flottmann F, Kniep H, Deb-Chatterji M, Schon G, Thomalla G, Kemmling A, Fiehler J, Meyer L; German Stroke Registry-Endovascular Treatment (GSR-ET) Study Group. Association of Thrombectomy With Functional Outcome for Patients With Ischemic Stroke Who Presented in the Extended Time Window With Extensive Signs of Infarction. JAMA Netw Open. 2022 Oct 3;5(10):e2235733. doi: 10.1001/jamanetworkopen.2022.35733.
- Deb-Chatterji M, Pinho J, Flottmann F, Meyer L, Broocks G, Brekenfeld C, Reich A, Fiehler J, Gerloff C, Thomalla G; GSR-ET Investigators. Health-related quality of life after thrombectomy in young-onset versus older stroke patients: a multicenter analysis. J Neurointerv Surg. 2022 Nov;14(11):1145-1150. doi: 10.1136/neurintsurg-2021-017991. Epub 2021 Dec 7.
- Kniep H, Bechstein M, Broocks G, Brekenfeld C, Flottmann F, van Horn N, Geest V, Faizy TD, Deb-Chatterji M, Alegiani A, Thomalla G, Gellissen S, Fiehler J, Hanning U, Meyer L; German Stroke Registry-Endovascular Treatment (GSR-ET). Early surrogates of outcome after thrombectomy in posterior circulation stroke. Eur J Neurol. 2022 Nov;29(11):3296-3306. doi: 10.1111/ene.15519. Epub 2022 Aug 28.
- Herm J, Schlemm L, Siebert E, Bohner G, Alegiani AC, Petzold GC, Pfeilschifter W, Tiedt S, Kellert L, Endres M, Nolte CH. How do treatment times impact on functional outcome in stroke patients undergoing thrombectomy in Germany? Results from the German Stroke Registry. Int J Stroke. 2021 Oct;16(8):953-961. doi: 10.1177/1747493020985260. Epub 2021 Jan 20.
- Ettelt P, Maier IL, Schnieder M, Bahr M, Behme D, Psychogios MN, Liman J; GSR-ET Collaborators. Bridging therapy is associated with improved cognitive function after large vessel occlusion stroke - an analysis of the German Stroke Registry. Neurol Res Pract. 2020 Jul 27;2:29. doi: 10.1186/s42466-020-00079-9. eCollection 2020.
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2015年6月1日
初级完成 (预期的)
2025年6月1日
研究完成 (预期的)
2025年6月1日
研究注册日期
首次提交
2017年11月22日
首先提交符合 QC 标准的
2017年11月22日
首次发布 (实际的)
2017年11月29日
研究记录更新
最后更新发布 (估计)
2022年12月29日
上次提交的符合 QC 标准的更新
2022年12月28日
最后验证
2022年11月1日
更多信息
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打电话d90的临床试验
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Makerere UniversityInfectious Diseases Institute, Uganda完全的
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University of MichiganNational Institute of Mental Health (NIMH)完全的