Neuropsychologic and Electrophysiological Features of Cancer-Related Cognitive Side Effects in Racial and Ethnic Minority Breast Cancer Patients

Inclusion Criteria:

• Is at least 18 years old, but not older than 61 years old;
• Is female;
• Is Hispanic of any race or Black/African American
• Is fluent in English (see explanation in Section 7.0 Assessment / Evaluation Plan - Language Determination);
• Has a diagnosis of breast cancer (Stage I-III);
• Is treatment naïve and scheduled to receive chemotherapy, radiation, or endocrine therapy.

Healthy Control Subject Inclusion Criteria

• Is at least 18 years old, but not older than 61 years old;
• Is female;
• Is Hispanic or Black Non-Hispanic;
• Is fluent in English

Exclusion Criteria:

• Participants with neurologic illnesses affecting cognition, (i.e., Traumatic Brain Injury with a loss of consciousness >30 min., etc.) or severe psychiatric illness (i.e., schizophrenia, bipolar disorder, etc.);
• A hearing or visual deficit that impairs the ability to participate in the EEG tasks.
• Any condition which prevents application of the 160 EEG electrodes spaced evenly across the participant's scalp, which includes dreadlocks, and hair extensions applied by weaving, braiding, gluing, or clips-. unless the participants are willing to undo these styles prior to the EEG.
• Mini-Mental State Exam (MMSE) <16 (telephone version); MMSE <20 (in-person version)
• Prior chemotherapy for any malignancy
• Regularly taking opiates or take a daily, morning benzodiazepine or have taken a prn benzodiazepine prior to the assessment.

Healthy Control Subject Exclusion Criteria

• Current or historical cancer diagnosis (a previous diagnosis of basal cell skin carcinoma is allowable)
• History of neurologic illnesses affecting cognition, (i.e., Traumatic Brain Injury with a loss of consciousness >30 min., etc.) or severe psychiatric illness (i.e., schizophrenia, bipolar disorder, etc.);
• A hearing or visual deficit that impairs the ability to participate in the EEG tasks.
• Any condition which prevents application of the 160 EEG electrodes spaced evenly across the participant's scalp, which includes dreadlocks, and hair extensions applied by weaving, braiding, gluing, or clips-. unless the participants are willing to undo these styles prior to the EEG
• Mini-Mental State Exam (MMSE) <16 (telephone version); MMSE <20 (in-person version)
• Regularly taking opiates or takes a daily, morning benzodiazepine or has taken a prn benzodiazepine prior to the assessment.