- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01709526
How the Adolescent Inpatients Are Rehabilitated After Discharge (AdolInpRehabi)
Prospective Study the Adolescent Inpatients Rehabilitation
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
The whole prospective study sample consisted of 63 adolescents aged 13 to 18 years (40 girls and 23 boys)referred for psychiatric treatment to the adolescent psychiatric inpatient unit of Kuopio University Hospital, Finland. This study is part of the "Kliininen Laatuprojekti"- Depression Project in Kuopio University Hospital. Researcher UH, Doctor of Philosophy, has been the head of the study project. She has done this study by carrying, analysing, doing articles and writing abstracts and keeping lectures and congress sessions in Finland and aboard. In the same time she has done clinical work by caring adolescents in the hospital ward and in the therapy settings. UH has been the first writer in the articles, one article in national and three in international articles. This Doctoral dissertation has been presented 17th November 2007, supervisor was professor, MD. Mauri Marttunen.
The prospective study set out to investigate gender differences, psychosocial and cognitive functioning, self-image, and changes in these structured parameters, and the role of working alliance. More girls than boys were admitted to inpatient care. Mood and conduct disorders were the most common diagnoses. Girls more commonly had poor family relationships but more peers than boys. Violent and destructive behaviour were more common among boys, and they performed worse in tests assessing nonverbal cognitive performance and total immediate recall memory than girls. Both girls and boys had an impaired IQ at entry. Major impairment in functioning in several areas such as school, family relations, judgement and thinking was found among both genders.
The psychosocial functioning and cognitive performance of inpatients improved during treatment.
There were also improvements in intrapsychic constructs: in the psychological self-image, especially body-image, and in relationships with family members, particularly among emotionally-disturbed adolescents. Cognitive performance was significantly enhanced among subjects both with a good and with a poor working alliance. According to multivariate analyses, a better quality of working alliance and a greater number of therapy sessions were associated with positive changes in cognitive performance and self-image.
When subjects with major depression and conduct disorder were compared, nonverbal cognitive and general cognitive performance, body and self-image, and overall psychosocial functioning improved in both groups of subjects during treatment. More positive changes in self-image and family functioning were found among subjects with MDD.
Suicidal adolescents' treatment compliance and outcome were as good as those of non-suicidal patients. Their psychosocial functioning, cognitive performance, and both the psychological self and body-image improved during treatment. Positive changes in body-image associated significantly with a higher probability of improvement in psychosocial functioning, while a higher GAS score at entry was associated with a lower probability of functional improvement. In clinical practice, attention needs to be paid to structured assessment of adolescent psychiatric inpatients. This study suggests a need to combine at least regular individual therapy, pharmacotherapy, family interventions, and a school program. Since a good working alliance between the therapist and the adolescent patient seems to modify the treatment outcome, particular attention to creating a good alliance with the patient and intensive involvement of the parents in treatment are recommended. Prospective studies with a sufficient follow-up after discharge and well-designed intervention studies among adolescent inpatients are needed.
Now it is interested in how they are in recovery with the role of working alliance and improvement in the psychosocial functioning after discharge?
Study Type
Enrollment (Actual)
Phase
- Phase 2
- Phase 3
Contacts and Locations
Study Locations
-
-
-
Kuopio, Finland
- Kuopio University Hospital
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- psychiatric disease
- adolescents
- inpatient treatment
Exclusion Criteria:
- emergency psychiatric treatment
- under 4 weeks treatment
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Non-Randomized
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Other: Improvement after psychiatric inpatient treatment
|
Cognition, psychosocial functioning
Other Names:
|
Collaborators and Investigators
Sponsor
Collaborators
Investigators
- Principal Investigator: Ulla Hintikka, Kuopio University Hospital
Study record dates
Study Major Dates
Study Start
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- KUH5702803
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