Metacognitive Training Program With Depression (DMKT)

The participants of this study have been diagnosed with mild to moderate depression with no evidence of suicidal actions prior to recruitment. All recruited subjects receive standard therapy and participate in a metacognitive training program (D-MKT) independently of study participation. Diagnostic and therapeutical interventions are not part of this study. As part of this study, the change of cognitive and psychosocial achievement/behavior in patients with mild to moderate depression after taking part in the training program is being investigated. The training program seeks to enable group members to recognize and correct the often automatic and unconscious thought patterns that accompany depression, in part by viewing this depressive thought process at a distance (i.e., depersonalizing). In addition, dysfunctional assumptions about one's thought processes, as well as dysfunctional coping-strategies (i.e., thought suppression, rumination as problem-solving) are targeted (Lena Jelinek & Steffen Moritz, http://clinical-neuropsychology.de/metacognitive_training_for_depression.html). Within this study the cognitive and psychosocial behaviour changes are being investigated by neuropsychological assessment as well as questionnaires.

Study Overview

• Status: Terminated
• Conditions: Depression
• Intervention / Treatment: Behavioral: Metacognitive Training Program during mild to moderate depression

• Study Type: Observational
• Enrollment (Actual): 2

Contacts and Locations

Study Locations

• Switzerland
  • Zürich, Switzerland, 8032
    • Klinik für Alterspsychiatrie, Gerontopsychiatrisches Zentrum Hegibach

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 55 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

patients from our ambulatorium

Description

Inclusion Criteria:

• Participation in the Metacognitive Training Program
• Subjects with an age over 55 years and a diagnosed mild to moderate depression without psychotic Symptoms (F32, F33)
• Subjects have to be able to understand verbal and written information regarding treatment and procedures of the study.
• Subjects have to be able to understand and perform verbal and written tasks (cognitive tests/questionnaires).
• No evidence of suicidal tendency

Exclusion Criteria:

• Taking of medication or drugs that could influence cognition
• Diseases that prevent the subject from giving consent to this study or affect the collaboration during the examination
• Major and/or unstable physical diseases
• Strongly impaired vision/eye diseases
• Psychotic or manic symptoms
• Benzodiazepine addiction/dependency
• Suicidal tendency

Study Plan

How is the study designed?

Design Details

• Observational Models: Other
• Time Perspectives: Prospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Improvement of depression as measured by Becks Depression Inventory (BDI)	14 months
Improvement of depression as measured by Hamilton Depression Scale (HAMD)	14 months
Improvement of self-esteem as measured by Rosenberg Self-esteem Scale (RSE)	14 months
Improvement of dysfunctional coping strategies as measured by 10-Item-Version of the Response Styles Questionnaire in German (RSQ-D)	14 months
Improvement of dysfunctional coping strategies as measured by Dysfunctional Attitude Scale (DAS)	14 months
Improvement of satisfaction and subjective well-being as measured by World Health Organization Quality of Life - short version (WHOQOL-BREF)	14 months
Improvement of metacognitive thinking as measured by Metacognitions Questionnaire (MCQ)	14 months
Improvement of cognition as measured by Consortium to Establish a Registry for Alzheimer's Disease (CERAD-Plus)	14 months
Improvement of cognition as measured by 5-Point Test	14 months
Improvement of cognition as measured by Regensburger Wortflüssigkeitstest (RWT)	14 months
Improvement of cognition as measured by Tower of London	14 months
Improvement of cognition as measured by Wechsler Memory Scale Revised (WMS-R)	14 months
Improvement of cognition as measured by Trail Making Test (TMT)	14 months
Improvement of cognition as measured by Wechsler Adult Intelligence Scale (WAIS-IV)	14 months
Improvement of cognition as measured by Verbaler Lern- und Merkfähigkeitstest (VLMT)	14 months
Improvement of cognition as measured by Testbatterie zur Aufmerksamkeitsprüfung (TAP)	14 months
Improvement of cognition as measured by MWT	14 months
Improvement of cognition as measured by Cartoon Test	14 months
Improvement of cognition as measured by Faux Pas Test	14 months

Collaborators and Investigators

• Sponsor: Psychiatric University Hospital, Zurich

Study record dates

Study Major Dates

• Study Start: June 1, 2015
• Primary Completion (Actual): June 1, 2017
• Study Completion (Actual): June 1, 2017

Study Registration Dates

• First Submitted: March 26, 2015
• First Submitted That Met QC Criteria: April 8, 2015
• First Posted (Estimate): April 14, 2015

Study Record Updates

• Last Update Posted (Actual): November 21, 2017
• Last Update Submitted That Met QC Criteria: November 20, 2017
• Last Verified: November 1, 2017

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Behavioral Symptoms; Mental Disorders; Mood Disorders; Depression; Depressive Disorder
• Other Study ID Numbers: D-MKT - 2014-0421