Proximal Versus Distal Adductor Canal Blocks for Total Knee Arthroplasty

July 11, 2017 updated by: Neil Hanson, Benaroya Research Institute

A Comparison of Proximal Versus Distal Continuous Adductor Canal Blocks After Total Knee Arthroplasty

This study is designed to evaluate pain control of continuous adductor canal blocks placed proximally versus distally within the canal. The investigators hypothesize that there will be similar pain control between both groups.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

This study is a non-inferiority trial designed to determine whether placement of a continuous block within the adductor canal has a substantial impact on pain following total knee arthroplasty. Our primary outcome to determine this difference will be opioid consumption within the first day following surgery. Secondary outcomes will include: pain scores, quadriceps strength, and distance ambulated during physical therapy.

Study Type

Interventional

Enrollment (Actual)

76

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Washington
      • Seattle, Washington, United States, 98101
        • Virginia Mason Medical Center

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Unilateral Total Knee Arthroplasty
  • ASA physical status I-III
  • >18 years old
  • Non-pregnant
  • Consent to participate in the study

Exclusion Criteria:

  • Refusal to participate
  • <18 years old
  • Chronic opioid use
  • Localized infection Pregnancy Pre-existing coagulopathy Allergy to ultrasound gel or local anesthetics Contraindication to or refusal of spinal anesthetic

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Proximal
Proximal Adductor Canal Block
Procedure: Proximal Adductor Canal Block
Continuous Nerve Block
Active Comparator: Distal
Distal Adductor Canal Block
Procedure: Distal Adductor Canal Block
Continuous Nerve Block

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Opioid Consumption (IV Morphine Equivalents)
Time Frame: 24 Hours
Total opioid consumption
24 Hours

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Opioid Consumption (IV Morphine Equivalents)
Time Frame: 48 Hours
Total opioid consumption
48 Hours
Pain (Numeric Rating)
Time Frame: 48 Hours
NRS Pain Scale
48 Hours
Quadriceps Strength (% of Baseline)
Time Frame: 48 Hours
Maximum Isometric Voluntary Contraction
48 Hours
Distance Ambulated (Feet)
Time Frame: 48 Hours
Total distance ambulated during physical therapy
48 Hours

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Benaroya Research Institute

Investigators

  • Principal Investigator: Neil A Hanson, MD, Virginia Mason Medical Center

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

February 1, 2016

Primary Completion (Actual)

November 1, 2016

Study Completion (Actual)

November 1, 2016

Study Registration Dates

First Submitted

February 29, 2016

First Submitted That Met QC Criteria

March 2, 2016

First Posted (Estimate)

March 8, 2016

Study Record Updates

Last Update Posted (Actual)

July 13, 2017

Last Update Submitted That Met QC Criteria

July 11, 2017

Last Verified

July 1, 2017

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • IRB15118

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

Undecided

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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