- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04270968
Shock Wave Therapy On Cervical Pain Following Neck Dissection Surgery
February 12, 2020 updated by: Maged Basha, Qassim University
Efficacy of Extracorporeal Shock Wave Therapy (ESWT) on Cervical Myofascial Pain Following Neck Dissection Surgery
Myofascial pain syndrome (MPS) is a musculoskeletal disorder which is characterized by pain, muscle spasms and muscle tenderness, as well as a limited range of motion, weakness, and rarely, autonomous dysfunction.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
The occurrences of morbidity of the neck after cancer therapy were considerable and consisted of neck pain, loss of sensation, and decreased range of motion.
Extracorporeal shock wave therapy (ESWT) is one of the treatment options used for patients with myofascial pain syndrome through elimination of ischemia and modulation of vasoneuroactive substance (two major causes of trigger pathophysiology) and mechanical transduction as a cellular response to external stimulation.
the aim of this study was to investigate efficacy of extracorporeal shock wave therapy (ESWT) on cervical myofascial pain following neck dissection surgery.
Study Type
Interventional
Enrollment (Actual)
46
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
-
Cairo, Egypt, 11432
- Faculty of physical therapy, Cairo University
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
35 years to 60 years (ADULT)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Previous unilateral modified radical neck dissection.
- Patients with myofascial pain of upper trapezius for at least 3 months.
- Patients with palpable intramuscular taut band.
- Restriction in cervical ROM of lateral flexion and rotation.
- Provocation of the clinical symptoms by compression of the active trigger point
Exclusion Criteria:
- Patient who received medication or other therapies for MPS within the previous 2 months.
- Patients with pacemaker, pregnancy
- Open wound at the treatment area.
- Cervical myelopathy or radiculopathy, cervical spine fracture or spondylolisthesis.
- Rheumatoid arthritis.
- Coagulopathy.
- Epilepsy or any psychological disorder.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: TREATMENT
- Allocation: RANDOMIZED
- Interventional Model: PARALLEL
- Masking: SINGLE
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
EXPERIMENTAL: ESWT Group
received ESWT once a week for 4 weeks (0.25 ml/mm2, 1000 shocks) plus topical none steroidal anti-inflammatory drug (NSAID; 3 times /day for 4 weeks).
|
Extracorporeal Shock Wave Therapy (ESWT) has been introduced efficiently for more than twenty years as a treatment modality in orthopedic and musculoskeletal disorders.
ESWT has mechanical and cellular impacts on tissues regeneration and pain management through cavitation bubbles, acoustic micro streaming, and hyper-vascularity that can directly affect tissue calcifications, and modulate cell activity.
Other Names:
|
EXPERIMENTAL: control group
received only topical NSAID.
|
participants received 1% topical diclofenac gel on the tender points 3 times /day for 4 weeks.
Other Names:
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Visual analogue scale
Time Frame: before treatment
|
VAS was utilized for assessing and quantifying pain exhibited by the patients through a 0-10 cm scale.
Each subject was informed to mark the line according to the pain intensity experienced at that particular time where '0' means no pain and '10' means worst conceivable pain.
|
before treatment
|
Visual analogue scale
Time Frame: 2 weeks of treatment
|
VAS was utilized for assessing and quantifying pain exhibited by the patients through a 0-10 cm scale.
Each subject was informed to mark the line according to the pain intensity experienced at that particular time where '0' means no pain and '10' means worst conceivable pain.
|
2 weeks of treatment
|
Visual analogue scale
Time Frame: after 4 weeks of treatment
|
VAS was utilized for assessing and quantifying pain exhibited by the patients through a 0-10 cm scale.
Each subject was informed to mark the line according to the pain intensity experienced at that particular time where '0' means no pain and '10' means worst conceivable pain.
|
after 4 weeks of treatment
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Cervical range of motion assessment
Time Frame: before treatment
|
Cervical range of motion device (CROM; Performance Attainment Associates) was used for assessment of neck lateral flexion and rotation of both sides.
The CROM instrument contains a plastic frame put on the head above the nose and ears, attached at the head back by a Velcro strap to allow precise measure, re-measure and rotational motion in an upright place to avoid individual errors.
Two independent inclinometers are connected to the frame and point the head position in relation to the gravity line.
Another inclinometer indicates the head position in rotation in relation to a reference position.
|
before treatment
|
Cervical range of motion assessment
Time Frame: 2 weeks of treatment
|
Cervical range of motion device (CROM; Performance Attainment Associates) was used for assessment of neck lateral flexion and rotation of both sides.
The CROM instrument contains a plastic frame put on the head above the nose and ears, attached at the head back by a Velcro strap to allow precise measure, re-measure and rotational motion in an upright place to avoid individual errors.
Two independent inclinometers are connected to the frame and point the head position in relation to the gravity line.
Another inclinometer indicates the head position in rotation in relation to a reference position.
|
2 weeks of treatment
|
Cervical range of motion assessment
Time Frame: after 4 weeks of treatment
|
Cervical range of motion device (CROM; Performance Attainment Associates) was used for assessment of neck lateral flexion and rotation of both sides.
The CROM instrument contains a plastic frame put on the head above the nose and ears, attached at the head back by a Velcro strap to allow precise measure, re-measure and rotational motion in an upright place to avoid individual errors.
Two independent inclinometers are connected to the frame and point the head position in relation to the gravity line.
Another inclinometer indicates the head position in rotation in relation to a reference position.
|
after 4 weeks of treatment
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Investigators
- Study Director: MAGED A BASHA, Dr, Assistant Professor, Qassim University
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Guru K, Manoor UK, Supe SS. A comprehensive review of head and neck cancer rehabilitation: physical therapy perspectives. Indian J Palliat Care. 2012 May;18(2):87-97. doi: 10.4103/0973-1075.100820.
- Sist T, Miner M, Lema M. Characteristics of postradical neck pain syndrome: a report of 25 cases. J Pain Symptom Manage. 1999 Aug;18(2):95-102. doi: 10.1016/s0885-3924(99)00054-8.
- Bron C, Dommerholt JD. Etiology of myofascial trigger points. Curr Pain Headache Rep. 2012 Oct;16(5):439-44. doi: 10.1007/s11916-012-0289-4.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (ACTUAL)
November 3, 2018
Primary Completion (ACTUAL)
November 20, 2019
Study Completion (ACTUAL)
December 3, 2019
Study Registration Dates
First Submitted
February 11, 2020
First Submitted That Met QC Criteria
February 12, 2020
First Posted (ACTUAL)
February 17, 2020
Study Record Updates
Last Update Posted (ACTUAL)
February 17, 2020
Last Update Submitted That Met QC Criteria
February 12, 2020
Last Verified
February 1, 2020
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 1857PT
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
YES
IPD Plan Description
Individual participant data that underlie the results reported in this article, after de-identification (text, tables, and figure)
IPD Sharing Time Frame
Immediately following publication.
IPD Sharing Access Criteria
IPD will be available upon reasonable request by email from the main author after revising the requester qualification relevance to the topic of the study and approval of all co-authors within 1 month of receiving the request.
IPD Sharing Supporting Information Type
- STUDY_PROTOCOL
- SAP
- ICF
- ANALYTIC_CODE
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
Yes
product manufactured in and exported from the U.S.
Yes
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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