Effect of Hip Abductors Versus Knee Extensor Strengthening in Knee Osteoarthritis

May 1, 2021 updated by: Aalaa Mohamed El-Amin Sweelam, Cairo University

Effect of Hip Abductors Versus Knee Extensor Strengthening on Pain,Function and Quadriceps Isometric Strength in Knee Osteoarthritis

This study will try to answer the following question:

Would strengthening of hip abductors be equal to, or more effective than, knee extensors strengthening in improving pain, function and knee extensors isometric strength in patients with knee Osteoarthritis

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

A total of 70 patients with knee Osteoarthritis will be recruited All patients who will participate in the study will be referred by orthopedists. Patients with knee osteoarthritis will be included with age ranges from 50-70. They will be randomized into 2 groups; hip abductors strengthening (HAS) group a will receive hip abductors strengthening exercises, and knee extensors strengthening (KES) group will receive quadriceps strengthening exercise.

All patients who will meet the study criteria will get a complete knowledge of the objectives and procedures of the study.

Inclusion criteria:

  1. Patients with knee Osteoarthritis grade II- III Kellgren- Lawrence scores
  2. Their age is 50-70[Wang et al.,2019].
  3. Body mass index (BMI) 25-30.

Exclusion criteria:

  1. Patients who had surgical intervention in the knee and/or hip.
  2. Fracture in the lower limbs.
  3. Malignancy
  4. Any associated ligamentous injuries in knee or ankle.
  5. Spinal Cord Injury.
  6. Hormonal imbalance or on hormonal therapy
  7. Knee injection within the last 6 months prior to the study. Outcome parameters including Quadriceps Muscle Strength, the arabic version of Western Ontario and McMaster Universities Arthritis Index questionnaire total score and 3 subscales and Timed Up and Go test score

Study Type

Interventional

Enrollment (Actual)

70

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Cairo, Egypt
        • Faculty of physical therapy

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

50 years to 70 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  1. Patients with knee OA grade II- III Kellgren- Lawrence scores
  2. Their age is 50-70[Wang et al.,2019].
  3. Body mass index (BMI) 25-30.

Exclusion Criteria:

  1. Patients who had surgical intervention in the knee and/or hip.
  2. Fracture in the lower limbs.
  3. Malignancy
  4. Any associated ligamentous injuries in knee or ankle.
  5. Spinal Cord Injury.
  6. Hormonal imbalance or on hormonal therapy
  7. Knee injection within the last 6 months prior to the study.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: HAS group

hip abductors strengthening group

  1. Hip abduction -standing[Ferber et al.,2015].
  2. Sidelying hip abduction(clamshell)[Schache et al.,2016].
  3. lateral leg raise: in brief, the patients lie down on bed on the unaffected side, with the resistance band positioned around the distal thigh of the affected limb.;later, they raise the above lower limbs upwards for about 30 degrees, stay for 5- 10 s and slowly lay down[Xie et al.,2018].
  4. pelvic lift training, specifically, patients stand single-leg off the side at a 10-cm step. Later, they begin with the other limb that is lower than the step level, and contract the stance-limb hip abductor to raise the free leg to the step level while keeping the stance knee extended[Xie et al.,2018].
  5. Stretching Hamstrings [Fukuda et al.,2012]. Number of sets = 3, Repetitions =10 repetitions for each set
Other: Exercises
already included in arm/group descriptions.
Active Comparator: KES group

knee extensors strengthening group

  1. Isometric quadriceps setting
  2. Knee extensions from sitting with knee bend to 90
  3. Terminal knee extension from sitting.
  4. Stretching Hamstrings Number of sets = 3, Repetitions =10 repetitions for each set
Other: Exercises
already included in arm/group descriptions.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Quadriceps Muscle Strength assessment
Time Frame: 6 weeks
Quadriceps Muscle Strength assessment using Hand held Dynamometer
6 weeks
lower limb functional disability
Time Frame: 6 weeks
Measuring lower limb functional disability using The Arabic version of reduced WOMAC (ArWOMAC) index
6 weeks
Knee function
Time Frame: 6 weeks
Measuring function using The Timed Up & Go Test (TUG):
6 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Cairo University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

July 1, 2020

Primary Completion (Actual)

November 1, 2020

Study Completion (Actual)

November 1, 2020

Study Registration Dates

First Submitted

August 1, 2020

First Submitted That Met QC Criteria

August 4, 2020

First Posted (Actual)

August 7, 2020

Study Record Updates

Last Update Posted (Actual)

May 4, 2021

Last Update Submitted That Met QC Criteria

May 1, 2021

Last Verified

May 1, 2021

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Hip Abductors strength in KOA

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

Yes

IPD Plan Description

protocol copy, informed consent, statistical analysis

IPD Sharing Supporting Information Type

  • Study Protocol
  • Statistical Analysis Plan (SAP)
  • Informed Consent Form (ICF)

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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