- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05254496
The Dietary Guidelines 3 Diet Patterns Study (DG3D): Phase 2 (DG3D-Phase2)
Ensuring the Cultural Relevance of Dietary Guidelines Diet Patterns Among African Americans: Increasing Dietary Quality and Reducing Type 2 Diabetes Risk (Phase 2)
Based on the findings of our formative work, conduct a one-year intervention among African American Adults using revised culturally tailored materials to examine differences in Healthy Eating Index (HEI) and type 2 diabetes (T2DM) risk factors among participants (n=198) randomized to one of the 3 dietary patterns:
1) Healthy U.S.-Style Eating Pattern, 2) Healthy Mediterranean-Style Eating Pattern, and 3) Healthy Vegetarian Eating Pattern.
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
The U.S. Dietary Guidelines (USDG) form the basis of federal nutrition programs and policy and provide valuable guidance to health initiatives and industries. The updated 2015 USDG moved away from a focus on individual nutrients to a greater focus on dietary patterns. The USDG state that healthy eating goals can be met through a variety of dietary patterns, but present healthy diet in three main ways: 1) Healthy U.S.-Style Eating Pattern, 2) Healthy Mediterranean-Style Eating Pattern, and 3) Healthy Vegetarian Eating Pattern. Currently, US adults are falling short of the nutrition recommendations (fruit/vegetable intake, greens/beans, whole grains, etc.) set forth by the USDG and measured by the Healthy Eating Index (HEI). While the USDG are the basis of nutrition guidelines, the research informing these dietary pattern recommendations has largely been drawn from observational studies among mostly white populations. In addition, there has been very limited cultural-tailoring of these dietary patterns that would ensure that these diets are acceptable to diverse populations, in particular, African Americans (AAs) living in the south, who experience a disproportionate burden of chronic disease, especially type 2 diabetes (T2DM). Currently, US adults are not meeting nutrition recommendations (fruit/vegetable, whole grains, etc.) set forth by the USDG and measured by the Healthy Eating Index (HEI).
For this study, AA adult participants with overweight/obesity and ≥three T2DM risk factors will be recruited to participate in the following aim:
Based on the findings of our formative work, conduct a one-year intervention using revised culturally tailored materials to examine differences in HEI and T2DM risk factors among participants (n=198) randomized to one of the 3 dietary patterns. This will result in community-based strategies around presenting dietary guidelines in a way to effectively meet nutrition recommendations leading to significant impacts on health among AA adults.
Study Type
Enrollment (Anticipated)
Phase
- Not Applicable
Contacts and Locations
Study Contact
- Name: Mary Wilson, PhD
- Phone Number: 803-777-1902
- Email: NEWSOUL@mailbox.sc.edu
Study Locations
-
-
South Carolina
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Columbia, South Carolina, United States, 29208
- Recruiting
- University of South Carolina
-
Contact:
- Principal Investigator
- Phone Number: 803-777-3932
- Email: NEWSOUL@mailbox.sc.edu
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- 18-65 years of age
- BMI between 25- 49.9 kg/m2
- self-identify as African American
- live in the Columbia, SC area
- be able to attend all monitoring visits
- be willing to be randomized to either condition and be re-randomized if non-responsive
- be free of major health or psychiatric diseases, drug or alcohol dependency, thyroid conditions, diabetes, or pregnancy
Exclusion Criteria:
should not be pregnant (or have been pregnant in the last 6 months), anticipating on becoming pregnant in the next 12 months, or currently breastfeeding
o Women who are pregnant should not be pursuing weight loss and should be under the direct care of a physician. Therefore women who are pregnant or who are anticipating they might be pregnant should not participate in this study. If a woman becomes pregnant during the study, she will be advised to consult with her healthcare provider and will be dropped from the weight loss study.
- should be free of an eating disorder as screened by the Eating disorder Screen for Primary care [ESP]. (If a participant has an eating disorder, they will be given contact information for the eating disorder clinic at the University of South Carolina)
- no current participation in a weight loss program or taking weight loss medications (although participants may be trying to lose weight on their own)
- no recent or planned bariatric surgery
- no recent weight loss (>10 lbs in the last 6 months)
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Prevention
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: US Healthy Diet
Participants in this group will be assigned to follow the Healthy US dietary pattern as presented by the US Dietary Guidelines.
As described here https://www.nia.nih.gov/health/usda-food-patterns:
This eating pattern is based on the types and amounts of foods Americans typically consume.
The main types of food in this eating pattern include a variety of vegetables; fruits; whole grains; fat-free or low-fat dairy; seafood, poultry, meat, and eggs; and nuts, seeds, and soy products.
|
Participants will attend classes once per week for 6 months and then bi-weekly for 6 months.
|
Experimental: Mediterranean diet
Participants in this group will be assigned to follow the Mediterranean dietary pattern as presented by the US Dietary Guidelines.
As described here https://www.nia.nih.gov/health/usda-food-patterns:
This eating pattern contains more fruits and seafood and less dairy than the Healthy U.S.-Style Eating Pattern.
|
Participants will attend classes once per week for 6 months and then bi-weekly for 6 months.
|
Experimental: Vegetarian diet
Participants in this group will be assigned to follow the Vegetarian dietary pattern as presented by the US Dietary Guidelines.
As described here https://www.nia.nih.gov/health/usda-food-patterns:
This eating pattern contains no meat, poultry, or seafood.
Compared with the Healthy U.S.-Style Eating Pattern, it contains more soy products, eggs, beans and peas, nuts and seeds, and whole grains.
|
Participants will attend classes once per week for 6 months and then bi-weekly for 6 months.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Changes in dietary quality
Time Frame: 12 months
|
Changes in dietary quality as assessed by the Healthy Eating Index
|
12 months
|
Changes in body weight
Time Frame: 12 months
|
Changes in body weight
|
12 months
|
Changes in HgbA1c
Time Frame: 12 months
|
Changes in HgbA1c
|
12 months
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Changes in blood pressure
Time Frame: 12 months
|
Changes in systolic and diastolic blood pressure
|
12 months
|
Collaborators and Investigators
Sponsor
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- Pro00118661
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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