Motivations to Transplant Registry Participation

April 1, 2025 updated by: Lauren C. Daniel, Ph.D., Rutgers, The State University of New Jersey

Motivations for Stem Cell Transplant Registry Participation

The current study seeks to understand factors that influence college students' likelihood of participating the National Marrow Donor Program (NMDP)/Be the Match for bone marrow and stem cell donations. The secondary aim is to compare emotional and rational approaches to encouraging participation in the registry and how these approaches may impact intentions to participate in the NMDP.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

This study is a randomized controlled trial that will randomize participants to receive either an emotional appeal about a child with cancer who needs a bone marrow transplant or a rational appeal using data on the racial/ethnic disparities within the transplant registry.

Participants will be recruited through the Psychology Subject Pool, which will then link students to the study measures in an online survey. Participants will be asked their age to confirm eligibility to participate (students must be between 18-35), and eligible students will be presented with the consent form through the online survey system. Participants will then be asked to complete measures of demographic information, personality/psychological characteristics, and transplant-related knowledge, intentions, and attitudes. All participants will then be given background information on bone marrow transplants.

Randomization: Students will be randomized by sex in the online survey system to the emotional presentation condition or the rational presentation condition. The emotional condition will tell the story of a fictional pediatric patient with cancer who needs a transplant. The rational condition will describe the facts about the need for diversity in the registry.

After being presented with the rational or emotional appeal, participants will again be asked about their intentions to register, their motivations for registering, and their mood.

Study Type

Interventional

Enrollment (Actual)

397

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • New Jersey
      • Camden, New Jersey, United States, 08102
        • Rutgers University Camden

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 35 years (Adult)

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Rutgers Camden Students enrolled in Psych 101 and Method and Theory
  • Between the ages of 18-35

Exclusion Criteria:

  • Students under 18 years of age or over 36 or older will be excluded.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Health Services Research
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Emotional Group
Participants will be randomly assigned to receive an emotional or rational appeal, stratified by sex.
Behavioral: Emotional Appeal
Participants will be presented with a short vignette about a child undergoing cancer treatment and needing a bone marrow transplant in order to survive cancer.
Experimental: Rational Group
Participants will be randomly assigned to receive an emotional or rational appeal, stratified by sex.
Behavioral: Rational Appeal
Participants will be presented with data regarding the importance of considering race/ethnicity when looking for a bone marrow transplant donor and the likelihood of finding a match based on the patient's racial/ethnic background.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Intention to Register
Time Frame: Baseline and after the experimental manipulation (Post-Intervention)
Participants rated the likelihood of registering on a 1-7 scale with higher scores indicating greater intention to join the registry (better outcome). Participants were asked these questions before (baseline) and after (post-intervention) the experimental manipulation.
Baseline and after the experimental manipulation (Post-Intervention)

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Mood
Time Frame: Baseline and after experimental manipulation (Post-Intervention)
Participant mood was assessed on a 1-10 scale, with higher scores indicating a better mood. Participants were asked these questions before (baseline) and after (post-intervention) the experimental manipulation.
Baseline and after experimental manipulation (Post-Intervention)
Psychosocial and Demographic Correlates of Intentions to Register--Knowledge
Time Frame: Baseline
Participants completed a knowledge measure about bone marrow and stem cell transplant donation using true/false statements about transplant donation that was examined as a correlate of their intentions to register with the transplant registry. The measure was scored as a percent of items answered correctly, higher scores indicating better knowledge.
Baseline

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Rutgers, The State University of New Jersey

Investigators

  • Principal Investigator: Lauren C Daniel, Ph.D., Rutgers University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 10, 2022

Primary Completion (Actual)

November 6, 2023

Study Completion (Actual)

November 6, 2023

Study Registration Dates

First Submitted

September 15, 2022

First Submitted That Met QC Criteria

October 24, 2022

First Posted (Actual)

October 27, 2022

Study Record Updates

Last Update Posted (Actual)

April 18, 2025

Last Update Submitted That Met QC Criteria

April 1, 2025

Last Verified

April 1, 2025

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • Pro2022000536

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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