- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05595382
Motivations to Transplant Registry Participation
Motivations for Stem Cell Transplant Registry Participation
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
This study is a randomized controlled trial that will randomize participants to receive either an emotional appeal about a child with cancer who needs a bone marrow transplant or a rational appeal using data on the racial/ethnic disparities within the transplant registry.
Participants will be recruited through the Psychology Subject Pool, which will then link students to the study measures in an online survey. Participants will be asked their age to confirm eligibility to participate (students must be between 18-35), and eligible students will be presented with the consent form through the online survey system. Participants will then be asked to complete measures of demographic information, personality/psychological characteristics, and transplant-related knowledge, intentions, and attitudes. All participants will then be given background information on bone marrow transplants.
Randomization: Students will be randomized by sex in the online survey system to the emotional presentation condition or the rational presentation condition. The emotional condition will tell the story of a fictional pediatric patient with cancer who needs a transplant. The rational condition will describe the facts about the need for diversity in the registry.
After being presented with the rational or emotional appeal, participants will again be asked about their intentions to register, their motivations for registering, and their mood.
Study Type
Enrollment (Actual)
Phase
- Not Applicable
Contacts and Locations
Study Locations
-
-
New Jersey
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Camden, New Jersey, United States, 08102
- Rutgers University Camden
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Description
Inclusion Criteria:
- Rutgers Camden Students enrolled in Psych 101 and Method and Theory
- Between the ages of 18-35
Exclusion Criteria:
- Students under 18 years of age or over 36 or older will be excluded.
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Health Services Research
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Emotional Group
Participants will be randomly assigned to receive an emotional or rational appeal, stratified by sex.
|
Participants will be presented with a short vignette about a child undergoing cancer treatment and needing a bone marrow transplant in order to survive cancer.
|
Experimental: Rational Group
Participants will be randomly assigned to receive an emotional or rational appeal, stratified by sex.
|
Participants will be presented with data regarding the importance of considering race/ethnicity when looking for a bone marrow transplant donor and the likelihood of finding a match based on the patient's racial/ethnic background.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Intention to register
Time Frame: Baseline
|
Participants will be asked 2 questions about whether they will register and the rate the likelihood of registering.
They will be asked these questions before and after the experimental manipulation.
|
Baseline
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Mood
Time Frame: Baseline
|
Participant mood will be assessed pre/post survey, asking participants to rate their current mood on a 1-10 scale.
|
Baseline
|
Psychosocial and Demographic Correlates of intentions to register
Time Frame: Baseline
|
Participants will complete demographic, personality measures and, knowledge measures that will be examined as correlates of their intentions to register with the transplant registry.
|
Baseline
|
Collaborators and Investigators
Investigators
- Principal Investigator: Lauren C Daniel, Ph.D., Rutgers University
Publications and helpful links
General Publications
- CROWNE DP, MARLOWE D. A new scale of social desirability independent of psychopathology. J Consult Psychol. 1960 Aug;24:349-54. doi: 10.1037/h0047358. No abstract available.
- Billen A, Madrigal JA, Scior K, Shaw BE, Strydom A. Donation of peripheral blood stem cells to unrelated strangers: A thematic analysis. PLoS One. 2017 Oct 25;12(10):e0186438. doi: 10.1371/journal.pone.0186438. eCollection 2017.
- Butterworth VA, Simmons RG, Bartsch G, Randall B, Schimmel M, Stroncek DF. Psychosocial effects of unrelated bone marrow donation: experiences of the National Marrow Donor Program. Blood. 1993 Apr 1;81(7):1947-59.
- Fingrut W, Parmar S, Cuperfain A, Rikhraj K, Charman E, Ptak E, Kahlon M, Graham A, Luong S, Wang YG, Yu J, Arora N, Suppiah R, Li EW, Lee A, Welsh C, Benzaquen M, Thatcher A, Baharmand I, Ladd A, Petraszko T, Allan D, Messner H. The Stem Cell Club: a model for unrelated stem cell donor recruitment. Transfusion. 2017 Dec;57(12):2928-2936. doi: 10.1111/trf.14327. Epub 2017 Sep 24.
- Gardner, Paul. (1987). Measuring ambivalence to science. Journal of Research in Science Teaching. 24. 241 - 247. 10.1002/tea.3660240305.
- Kaster EC, Rogers CR, Jeon KC, Rosen B. Getting to the Heart of Being the Match: A Qualitative Analysis of Bone Marrow Donor Recruitment and Retention Among College Students. Health Educ (Muncie). 2014 Spring;46(1):14-19.
- Monaghan M, Yi QL, Green M, Campbell T, Weiss JT, Dibdin N, Mercer D, Elmoazzen H, Allan DS. Factors associated with registrant availability for unrelated adult donor hematopoietic stem cell donation: Analysis of the stem cell registry at Canadian Blood Services. Transfusion. 2021 Jan;61(1):24-28. doi: 10.1111/trf.16129. Epub 2020 Oct 21.
- Narayanan P, Wolanskyj A, Ehlers SL, Litzow MR, Patnaik MS, Hogan WJ, Hashmi SK. Medical Students' Knowledge, Familiarity, and Attitudes towards Hematopoietic Stem Cell Donation: Stem Cell Donation Behaviors. Biol Blood Marrow Transplant. 2016 Sep;22(9):1710-1716. doi: 10.1016/j.bbmt.2016.06.014. Epub 2016 Jun 22.
- National Marrow Donor Program (2013). Key Figures and Facts. www.bethematch.com
- Onitilo AA, Lin YH, Okonofua EC, Afrin LB, Ariail J, Tilley BC. Race, education, and knowledge of bone marrow registry: indicators of willingness to donate bone marrow among African Americans and Caucasians. Transplant Proc. 2004 Dec;36(10):3212-9. doi: 10.1016/j.transproceed.2004.10.019.
- Rose A, Peters N, Shea JA, Armstrong K. Development and testing of the health care system distrust scale. J Gen Intern Med. 2004 Jan;19(1):57-63. doi: 10.1111/j.1525-1497.2004.21146.x.
- Rosenberg, M. (1965). Rosenberg self-esteem scale. Journal of Religion and Health.
- Rushton, J. P., Chrisjohn, R. D., & Fekken, G. C. (1981). The altruistic personality and the self-report altruism scale. Personality and individual differences, 2(4), 293-302.
- Surana, P. K., & Lomas, T. (2014). The power of charity: Does giving away money improve the wellbeing of the donor. Indian Journal of Positive Psychology, 5(3), 223-230.
- Studts JL, Ruberg JL, McGuffin SA, Roetzer LM. Decisions to register for the National Marrow Donor Program: rational vs emotional appeals. Bone Marrow Transplant. 2010 Mar;45(3):422-8. doi: 10.1038/bmt.2009.174. Epub 2009 Aug 3.
- Vasconcellos A, Nunes A, Feller E. Knowledge, attitudes, and behaviors regarding the bone marrow registry among college and medical students in Rhode Island. Med Health R I. 2011 Oct;94(10):302-5. No abstract available.
- Vekaria KM, Hammell AE, Vincent L, Smith M, Rogers T, Switzer GE, Marsh AA. The role of prospection in altruistic bone marrow donation decisions. Health Psychol. 2020 Apr;39(4):316-324. doi: 10.1037/hea0000819. Epub 2019 Nov 14.
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Other Study ID Numbers
- Pro2022000536
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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