Effect of Early Eating and Stair Climbing on Body Composition

Effect of Early Time Restricted Eating and Brief Intense Stair Climbing on Body Composition

To our knowledge, as of this day there are only four studies which examined the effects of eTRE with a duration of 12 weeks. There are no studies that examined this phenomenon beyond 12 weeks, one study that lasted five weeks and four studies that lasted 4 weeks or less, some even days. The four studies that lasted 12 weeks in duration all have opportunities to improve upon, which will be discussed here. The first study performed by Gabel et al., focused primarily on measuring body weight, not body composition in older adults. The eating window also began later in the morning at 1000h and finished at 1800h. There also was no restriction on participants consuming caffeine during the fasting window. The second study conducted by Gasmi et al., was focused on strictly older male participants that were active and healthy, again, without measuring body composition. The third study conducted by Wilkinson et al., did not measure body composition and the eating window lasted 10 hours instead of 8. The fourth study performed by Chow et al., examined eTRE with adults aged 45+/-12 years old and did not mention any exclusion criteria based upon physical activity levels or restrictions on caffeine/artificial sweetener intake during the fasting window. Furthermore, none of the studies mentioned above examined eTRE against eTRE with Brief Intense Stair Climbing (BISC) directly. We believe that the proposed study will address the concerns mentioned previously and further knowledge associated with eTRE.

Study Overview

• Status: Not yet recruiting
• Conditions: eTRE (Early Time Restricted Eating); eTRE With BISC (Brief Intense Stair Climbing)
• Intervention / Treatment: Behavioral: eTRE; Behavioral: eTRE with BISC

• Study Type: Interventional
• Enrollment (Anticipated): 30
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Reed Zehr, MSc; Phone Number: 519-661-2111; Email: rzehr2@uwo.ca

Study Locations

• Canada
  • Ontario
    • London, Ontario, Canada, N6A3K7
      • Exercise Nutrition Laboratory, Western University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 39 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• sedentary- lightly physically active (<7,500 steps daily)
• BMI > 25 • 18-39 years old

Exclusion Criteria:

• Have diabetes (self-reported)

  • Have history of smoking (self-reported)
  • Have history of cardiovascular disease (self-reported)
  • Have BMI of <24.9
• Are pregnant or become pregnant during the study (self-reported)
• Take medication for weight loss (self-reported)
• Physical activity level > 7500 steps/day
• Unstable weight for 3 months prior to commencement of study (>4kg weight loss/gain) • Employed in a shift work position

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: eTRE; participants allocated to this group are required to consume food during 0800h and 1600h.	Behavioral: eTRE; eating between 0800h and 1600h daily
Active Comparator: eTRE with BISC; participants allocated to this group are required to consume food during 0800h and 1600h as well as complete 3 sessions of BISC per week.	Behavioral: eTRE with BISC; eating between 0800h and 1600h daily and completing 3 sessions of BISC per week of study duration

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Body Composition	fat mass vs. fat-free mass via BodPod	less than 5 mins

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
upper body strength test	3-rep max bench press	< 15 mins
lower body strength test	3-rep max leg press	< 15 mins
health related quality of life questionnaire	subjective feelings of well-being per participant	< 10 mins

Collaborators and Investigators

• Sponsor: Western University, Canada

Study record dates

Study Major Dates

• Study Start (Anticipated): March 1, 2023
• Primary Completion (Anticipated): December 31, 2023
• Study Completion (Anticipated): December 31, 2023

Study Registration Dates

• First Submitted: January 19, 2023
• First Submitted That Met QC Criteria: January 19, 2023
• First Posted (Estimate): January 30, 2023

Study Record Updates

• Last Update Posted (Estimate): January 30, 2023
• Last Update Submitted That Met QC Criteria: January 19, 2023
• Last Verified: January 1, 2023

More Information

Terms related to this study

• Other Study ID Numbers: 122046

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No