Thorough Flushing Strategy During Colonoscopy Examination

Clinical Study on the Application of Thorough Flushing Strategy During Colonoscopy Examination

The investigators plan to adopt a thorough flushing strategy when withdrawing the endoscope, and have zero tolerance for the liquid and foam in the intestinal lumen. Observe and compare the impact of this strategy with traditional limited degree suction methods on the results of colonoscopy. The research group and the control group respectively adopted a thorough flushing strategy and a limited flushing strategy, and compared the total time of colonoscopy examination, the time of withdrawal, the detection rate of polyps, the detection rate of small polyps, and the amount of flushing fluid between the two groups. Analyze the value of thorough flushing strategy for the efficiency and quality of colonoscopy examination.

Study Overview

• Status: Completed
• Conditions: Colonoscopy
• Intervention / Treatment: Procedure: thorough flushing

Detailed Description

Most physicians do not adopt a strategy of complete suction of fluid from the intestinal lumen during colonoscopy. There are both concerns about the time required for colonoscopy and the possibility of inability to thorough cleannig up. Some endoscopists believe that the visual field for partial cleaning of fecal water is acceptable and does not affect observation. This study aims to make an observation and comparison based on the existing problems mentioned above. With the help of direct water injection system, the investigators plan to adopt a thorough flushing strategy when withdrawing the endoscope, and have zero tolerance for the liquid and foam in the intestinal lumen. Observe and compare the impact of this strategy with traditional limited degree suction methods on the results of colonoscopy. The research group and the control group respectively adopted a thorough flushing strategy and a limited flushing strategy, and compared the total time of colonoscopy examination, the time of withdrawal, the detection rate of polyps, the detection rate of small polyps, and the amount of flushing fluid between the two groups. Analyze the value of thorough flushing strategy for the efficiency and quality of colonoscopy examination.

• Study Type: Observational
• Enrollment (Actual): 160

Contacts and Locations

• Study Contact: Name: Hang Zhao, Professor; Phone Number: 8618621186288; Email: zhaohang@shutcm.edu.cn

Study Locations

• China
  • Shanghai, China
    • Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Probability Sample

Study Population

160 patients were selected for colonoscopy examination and randomly assigned to the study group and control group. The two groups used a thorough flushing strategy and a limited flushing strategy to complete colonoscopy examination. The research group adopted a thorough flushing strategy, while the control group adopted a limited flushing strategy. The thorough flushing strategy refers to the thorough flushing of all liquid and foam accumulation areas during the inspection. Make all the liquid accumulation parts in the intestinal cavity free of aspiratable liquid retention. The limited flushing strategy refers to not pursuing full liquid suction, but flushing until it is clear enough for observation. The limited flushing strategy is currently the conventional flushing method for colonoscopy.

Description

Inclusion Criteria:

• People without contraindications for colonoscopy

Exclusion Criteria:

• Patients diagnosed with colon polyps

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
limited; patients adopted limited flushing strategy
thorough; Thorough flushing strategy	Procedure: thorough flushing; The thorough flushing strategy refers to the thorough flushing of all liquid and foam accumulation areas during the inspection. Make all liquid accumulation parts in the intestinal cavity free of aspiratable liquid retention

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
time of examination	the time from insertion to exit the anus	1week
time of insertion	the time from insertion to arriving at cecum	1week
time of withdrawl	the time from cecum to anus	1week
number of polyps	the number of polyps found	1week
location of polyps	the location of polyps found	1week
shape of polyps	the shape of polyps found, classified into lateral, senssile and pediculated three types	1week

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Boston score	the Boston score of bowel preparation (from 0-9)	1week
volume of water	volume of water used for flushing	1week

Collaborators and Investigators

• Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
• Collaborators: Shanghai University of Traditional Chinese Medicine

Study record dates

Study Major Dates

• Study Start (Actual): August 1, 2023
• Primary Completion (Actual): December 31, 2023
• Study Completion (Actual): January 31, 2024

Study Registration Dates

• First Submitted: October 26, 2023
• First Submitted That Met QC Criteria: November 3, 2023
• First Posted (Actual): November 7, 2023

Study Record Updates

• Last Update Posted (Actual): February 13, 2024
• Last Update Submitted That Met QC Criteria: February 10, 2024
• Last Verified: February 1, 2024

More Information

Terms related to this study

• Keywords: colonoscopy, quality, polyps
• Additional Relevant MeSH Terms: Skin Manifestations; Flushing
• Other Study ID Numbers: KY-103-01

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No