- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06253039
"Living Low - Training High" Methods and Physiological Responses in Well-trained Swimmers
Effects of Innovative "Living Low - Training High" Methods on Performance and Physiological Responses in Well-trained Swimmers.
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Recently, several new "living low training high" (LLTH) methods involving repeated sprints in hypoxia have shown promising results, especially in team sports. However, the underlying mechanisms remain mostly unclear, as does its effectiveness in improving swimming performance.
Hypoxemia can be induced by exposure to ambient hypoxia conditions, by voluntary hypoventilation at low lung volume, or by vascular occlusion (namely, blood flow restriction). Swimming performance is influenced by aerobic and anaerobic metabolism and could benefit from these different LLTH methods.
This project aims to compare the effects of repeated sprint training performed with a ski-ergometer 1) in a hypoxic chamber and 2) with voluntary hypoventilation on the performance of swimmers, as well as to characterize cardiorespiratory, metabolic, and muscle oxygenation adaptations that may contribute to the improvements achieved after four weeks of each of these types of training.
All groups will be evaluated before and after the supervised training period in three testing sessions in normoxia, separated by at least 24 hours within 7 days. Swimmers will perform: 1) time-trial (100 m front crawl) in the swimming pool to determine performance, V̇̇O2 peak, and lactate concentration following the test; 2) incremental test to exhaustion in the swim-ergometer to determine aerobic peak power, cardiorespiratory responses (V̇̇O2max, ventilatory thresholds), and maximal tissue deoxygenation; 3) time-trial test in the ski-ergometer (100 m) to access performance, muscle and pulmonary oxygen uptake kinetics, and the relative contribution of energetic systems.
Training sessions will be performed in the ski-ergometer and consist of 4 sets of 5x6s all-out sprints with 24s and 5 min of passive rest between the sprints and sets, respectively. In all testing and training sessions, pulse oxygen saturation will be measured for safety purposes.
Study Type
Enrollment (Estimated)
Phase
- Not Applicable
Contacts and Locations
Study Locations
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Cruz-Quebrada
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Lisbon, Cruz-Quebrada, Portugal, 1495-002
- Faculty of Human Kinetics
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Contact:
- Joana Reis, PhD
- Phone Number: 00351214149174
- Email: joanareis@fmh.ulisboa.pt
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Contact:
- Cristina P Monteiro, PhD
- Phone Number: 00351214149174
- Email: cmonteiro@fmh.ulisboa.pt
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
Description
Inclusion Criteria:
- Swimmers from both sexes;
- With regular participation in National Championships;
- More than five years of training experience;
- No recent exposure/acclimatization to altitude;
- No recent exposition to Blood Flow Restriction training.
Exclusion Criteria:
- athletes who had an acclimatization experience or exposure to altitude lasting more than 10 days in the last 6 months;
- pregnant or postpartum women;
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Other
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Normobaric hypoxia (RSH)
The RSH group will perform training sessions in a normobaric hypoxic chamber at a simulated altitude of 3000 meters (FiO2 14.5%)
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Experimental: Hypoventilation (RSH-VHL)
RSH-VHL group will be asked to exhale down to functional residual capacity just before each repetition and then hold their breath until the end of the sprint
|
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Active Comparator: Normoxia (RSN)
The control group will perform the training sessions in normoxia (FIO2, 20.9%)
|
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Ventilatory thresholds and maximum oxygen consumption
Time Frame: Before and after 4 weeks of supervised training period
|
mL/kg·min
|
Before and after 4 weeks of supervised training period
|
Lactate concentration
Time Frame: Before and after 4 weeks of supervised training period
|
mmol.L-1
|
Before and after 4 weeks of supervised training period
|
Muscle oximetry
Time Frame: Before and after 4 weeks of supervised training period
|
Near-infrared spectroscopy (NIRS)
|
Before and after 4 weeks of supervised training period
|
Time-trial
Time Frame: Before and after 4 weeks of supervised training period
|
seconds
|
Before and after 4 weeks of supervised training period
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Heart rate
Time Frame: Before and after 4 weeks of supervised training period
|
bpm
|
Before and after 4 weeks of supervised training period
|
Arterial oxygen saturation
Time Frame: Before and after 4 weeks of supervised training period
|
Oxymetry (%)
|
Before and after 4 weeks of supervised training period
|
Collaborators and Investigators
Sponsor
Collaborators
Study record dates
Study Major Dates
Study Start (Estimated)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- RSH swimmers
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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