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Effects of Two Aquatic Training Models in Physiological Parameters of Elderly Dyslipidemic Women.

9 september 2016 uppdaterad av: Hospital de Clinicas de Porto Alegre

Effects of Two Aquatic Training Models in Physiological Parameters of Elderly Dyslipidemic Women: a Randomized Controlled Clinical Trial.

This study aims to compare the effects of two water-based training models in physiological parameters of dyslipidemic elderly women. Thus, a randomized controlled clinical trial will be conducted in parallel with the participation of 45 dyslipidemic elderly women.

Studieöversikt

Status

Avslutad

Betingelser

Intervention / Behandling

Detaljerad beskrivning

The women will be randomly divided into three groups: water aerobics training (WA), resistance aquatic training (WR) and the third is the control group (who will perform relaxation sessions under water). The three groups will attend classes during 10 weeks, with two weekly sessions of 45 minutes each. The WA and WR groups will use the same four exercises in their training.

The WA group will be trained using the interval method, performing six blocks of five minutes each one, alternating four minutes at intensities corresponding to 90 to 100% of the heart rate corresponding to the second ventilatory threshold (HRVT2) and one minute at intensities between 80 and 90% HRVT2.

The WR group will perform four to eight sets of 20 to 10 seconds along the macrocycle, always at maximal speed execution of the exercises.

Will be measured, before and after the period of 10 weeks of intervention, biochemical, cardiorespiratory, neuromuscular and hemodynamic variables, parameters of quality of life and depressive symptoms in addition to the cardiovascular risk score of the participants of the three groups.

Data will be described by means values and lower and upper limits, with a 95% confidence interval. Comparisons between and within groups were performed using the method of generalized estimates of equations (GEE), with Bonferroni post hoc, adopting a 0.05 significance level.

Studietyp

Interventionell

Inskrivning (Faktisk)

45

Fas

  • Inte tillämpbar

Deltagandekriterier

Forskare letar efter personer som passar en viss beskrivning, så kallade behörighetskriterier. Några exempel på dessa kriterier är en persons allmänna hälsotillstånd eller tidigare behandlingar.

Urvalskriterier

Åldrar som är berättigade till studier

60 år till 75 år (Vuxen, Äldre vuxen)

Tar emot friska volontärer

Nej

Kön som är behöriga för studier

Kvinna

Beskrivning

Inclusion Criteria:

  • being female, aged between 60 and 75, sedentary (not practicing any kind of regular, supervised physical activity in the last three months), have any type of dyslipidemia.

Exclusion Criteria:

  • women who are smokers, suffering from cardiovascular disease with associated complications and those with orthopedic diseases that prevented the practice of systematic physical exercise, users of hormone therapy drugs and lipid-lowering medications.

Studieplan

Det här avsnittet ger detaljer om studieplanen, inklusive hur studien är utformad och vad studien mäter.

Hur är studien utformad?

Designdetaljer

  • Primärt syfte: Behandling
  • Tilldelning: Randomiserad
  • Interventionsmodell: Parallellt uppdrag
  • Maskning: Enda

Vapen och interventioner

Deltagargrupp / Arm
Intervention / Behandling
Experimentell: WA (Water Aerobics Training)
Water aerobics training.
Övrig: Water aerobics training.
The WA group will be trained adopting the interval method, performing six blocks of five minutes each one, alternating four minutes at intensities corresponding to 90 to 100% of the heart rate corresponding to the second ventilatory threshold (HRVT2) and one minute at intensities between 80 and 90% HRVT2.
Andra namn:
  • WA
Experimentell: WR (Water Resistance Training)
Resistance aquatic training.
Övrig: Water resistance training.
The WR group will perform four to eight sets of 20 to 10 seconds along the macrocycle, always at maximal speed execution of the exercises.
Andra namn:
  • WR
Aktiv komparator: CG (Control Group)
Control Group.
Övrig: Control Group
The control group will perform relaxation classes, including meditation, balance exercises, coordination exercises.
Andra namn:
  • CG

Vad mäter studien?

Primära resultatmått

Resultatmått
Åtgärdsbeskrivning
Tidsram
Total Cholesterol (TC) Change
Tidsram: Change from baseline total cholesterol at 10 weeks
This variable will be measured through blood collection after 12 hours fasting. The analysis will be performed through the enzymatic method using kits Siemens, in automated equipment Advia 1800.
Change from baseline total cholesterol at 10 weeks

Sekundära resultatmått

Resultatmått
Åtgärdsbeskrivning
Tidsram
Triglycerides (TG) Change
Tidsram: Change from baseline triglycerides at 10 weeks
This variable will be measured through blood collection after 12 hours fasting. The analysis will be performed through the enzymatic method using kits Siemens, in automated equipment Advia 1800.
Change from baseline triglycerides at 10 weeks
High Density Lipoprotein (HDL) Change
Tidsram: Change from baseline HDL at 10 weeks
This variable will be measured through blood collection after 12 hours fasting. The analysis will be performed through the enzymatic method using kits Siemens, in automated equipment Advia 1800.
Change from baseline HDL at 10 weeks
C-Reactive Protein (CRP) Change
Tidsram: Change from baseline C-reactive protein at 10 weeks
This variable will be measured through blood collection after 12 hours fasting. The analysis will be performed through the turbidimetric method in Cobas Mira Plus equipment, with the Biotechnical Kit for ultrasensitive C-reactive protein.
Change from baseline C-reactive protein at 10 weeks
Low Density Lipoprotein (LDL) Change
Tidsram: Change from baseline LDL at 10 weeks
This variable will be estimated by Friedewald equation.
Change from baseline LDL at 10 weeks
Total Cholesterol/High Density Lipoprotein Ratio (TC/HDL ratio) Change
Tidsram: Change from baseline TC/HDL at 10 weeks
This variable will be estimated by the simple division of variables.
Change from baseline TC/HDL at 10 weeks
Peak Oxygen Consumption (VO2peak) Change
Tidsram: Change from baseline VO2peak at 10 weeks
This outcome will be measure through maximal progressive treadmill test, using the portable gas analyser VO2000 equipment.
Change from baseline VO2peak at 10 weeks
Oxygen Consumption at anaerobic threshold (VO2VT2) Change
Tidsram: Change from baseline VO2VT2 at 10 weeks
This outcome will be measure through maximal progressive treadmill test, using the portable gas analyser VO2000 equipment.
Change from baseline VO2VT2 at 10 weeks
Heart Rate at anaerobic threshold (HRVT2) Change
Tidsram: Change from baseline HRVT2 at 10 weeks
This outcome will be measure through maximal progressive treadmill test, using a heart rate monitor (POLAR, FT1).
Change from baseline HRVT2 at 10 weeks
Rest Heart Rate (HRrest) Change
Tidsram: Change from baseline HRrest at 10 weeks
This outcome will be measure using a heart rate monitor (POLAR, FT1). The participants will remain seated in a quiet and controlled temperature room during 15 minutes prior to measurement of the heart rate.
Change from baseline HRrest at 10 weeks
Lipoprotein Lipase (LPL) Change
Tidsram: Change from baseline LPL at 10 weeks
This variable will be measured through blood collection after 12 hours fasting. The analysis will be performed using the LPL ELISA kit (Cell Biolabs). The results will be read in a microplate reader (ELISA).
Change from baseline LPL at 10 weeks
Maximal dynamic muscle strength of knees extensors (MSKE) Change
Tidsram: Change from baseline MSKE at 10 weeks
This outcome will be measured through the one-repetition maximal test (1RM).
Change from baseline MSKE at 10 weeks
Maximal dynamic muscle strength of knees flexors (MSKF) Change
Tidsram: Change from baseline MSKF at 10 weeks
This outcome will be measured through the one-repetition maximal test (1RM).
Change from baseline MSKF at 10 weeks
Maximal dynamic muscle strength of horizontal shoulder flexors (MSHSF) Change
Tidsram: Change from baseline MSHSF at 10 weeks
This outcome will be measured through the one-repetition maximal test (1RM).
Change from baseline MSHSF at 10 weeks
Rest Cardiac Output (COrest) Change
Tidsram: Change from baseline COrest at 10 weeks
This outcome will be measured through Impedance Cardiography (Physioflow Lab-1 equipment). The participants will remain seated in a quiet and controlled temperature room during 15 minutes prior to measurement of the cardiac output.
Change from baseline COrest at 10 weeks
Rest Stroke Volume (SVrest) Change
Tidsram: Change from baseline SVrest at 10 weeks
This outcome will be measured through Impedance Cardiography (Physioflow Lab-1 equipment). The participants will remain seated in a quiet and controlled temperature room during 15 minutes prior to measurement of the stroke volume.
Change from baseline SVrest at 10 weeks
Peak Cardiac Output (COpeak) Change
Tidsram: Change from baseline COpeak at 10 weeks
This outcome will be measured through Impedance Cardiography (Physioflow Lab-1 equipment), during a maximal progressive treadmill test.
Change from baseline COpeak at 10 weeks
Peak Stroke Volume (SVpeak) Change
Tidsram: Change from baseline SVpeak at 10 weeks
This outcome will be measured through Impedance Cardiography (Physioflow Lab-1 equipment), during a maximal progressive treadmill test.
Change from baseline SVpeak at 10 weeks
Rest Arterial Systolic Blood Pressure (SBPrest) Change
Tidsram: Change from baseline SBPrest at 10 weeks
This outcome will be measured through blood pressure ambulatory monitor (Meditech, ABPM-04). The participants will remain seated in a quiet and controlled temperature room during 15 minutes prior to measurement of the arterial systolic blood pressure.
Change from baseline SBPrest at 10 weeks
Rest Arterial Diastolic Blood Pressure (DBPrest) Change
Tidsram: Change from baseline DBPrest at 10 weeks
This outcome will be measured through blood pressure ambulatory monitor (Meditech, ABPM-04). The participants will remain seated in a quiet and controlled temperature room during 15 minutes prior to measurement of the arterial diastolic blood pressure.
Change from baseline DBPrest at 10 weeks
Cardiovascular Risk Score (CRS) Change
Tidsram: Change from baseline cardiovascular risk score at 10 weeks
The Reynolds Risk Score Instrument will be used to estimate the cardiovascular risk.
Change from baseline cardiovascular risk score at 10 weeks
Quality of Life Change
Tidsram: Change from baseline quality of life at 10 weeks
The quality of life will be estimated using the Whoqol-Bref instrument.
Change from baseline quality of life at 10 weeks

Samarbetspartners och utredare

Det är här du hittar personer och organisationer som är involverade i denna studie.

Sponsor

Hospital de Clinicas de Porto Alegre

Utredare

  • Huvudutredare: Ricardo Stein, Hospital de Clínicas de Porto Alegre

Studieavstämningsdatum

Dessa datum spårar framstegen för inlämningar av studieposter och sammanfattande resultat till ClinicalTrials.gov. Studieposter och rapporterade resultat granskas av National Library of Medicine (NLM) för att säkerställa att de uppfyller specifika kvalitetskontrollstandarder innan de publiceras på den offentliga webbplatsen.

Studera stora datum

Studiestart

1 december 2015

Primärt slutförande (Faktisk)

1 mars 2016

Avslutad studie (Faktisk)

1 maj 2016

Studieregistreringsdatum

Först inskickad

6 september 2016

Först inskickad som uppfyllde QC-kriterierna

9 september 2016

Första postat (Uppskatta)

14 september 2016

Uppdateringar av studier

Senaste uppdatering publicerad (Uppskatta)

14 september 2016

Senaste inskickade uppdateringen som uppfyllde QC-kriterierna

9 september 2016

Senast verifierad

1 september 2016

Mer information

Termer relaterade till denna studie

Nyckelord

Ytterligare relevanta MeSH-villkor

Andra studie-ID-nummer

  • 14-0547

Plan för individuella deltagardata (IPD)

Planerar du att dela individuella deltagardata (IPD)?

OBESLUTSAM

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