- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00923624
Patient Portal to Support Treatment Adherence
October 11, 2017 updated by: Kaiser Permanente
The purpose of this study is to conduct a randomized control trial of a behavioral intervention delivered by nurses via an electronic medical record (EMR) patient web portal to determine if this is an efficacious method for supporting medication adherence.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
300 adult HIV+ patients will be randomized to one of two arms.
150 will be assigned to receive secure messages focused on antiretroviral adherence from a nurse through the health plan EMR patient website.
150 will be assigned to an attention control comparison arm, and will receive electronic messages from a study staff member that provide information about the various features of the health plan patient website.
Patients will be invited by mail to be telephone screened for enrollment in the study.
Patients will be provided the opportunity to opt out of being contacted by the study.
Eligible and interested patients will be mailed an access code and separately emailed a link to a secure study website where they will complete a web consent form and a baseline web survey before being randomized to an intervention arm.
This trial will allow us to evaluate the effectiveness of using health information technology as an intervention delivery vehicle to improve patient disease management behaviors such as treatment adherence.
Study Type
Interventional
Enrollment (Actual)
304
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
California
-
Oakland, California, United States, 94612
- Kaiser Permanente Northern California
-
-
Washington
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Seattle, Washington, United States, 98101
- Group Health Research Institute
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- enrollment in GHC or KP health plans for at least 6 months
- expect to stay enrolled for 1 year in health plan
- HIV+
- currently prescribed antiretroviral medication
- regular access to a computer with internet capabilities and working email address and meet one of the following:
- gap in antiretroviral prescription refills based on 6 month refill records
- referral to study by provider team for adherence problems
Exclusion Criteria:
- dementia or psychosis diagnosis documented in medical record
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Active Comparator: staff emails
Attention control that includes staff sending emails with information about using health information technology system.
|
9 informational email messages sent by study staff about the features of the shared electronic medical record system and how to use them.
|
Experimental: study nurse messages
A series of 6 proactive secure messages and 3 proactive booster messages (for a total of 9 secure and personalized messages) sent by the study nurse via the EMR patient web portal.
|
9 messages tailored by the study nurse and guided by the IMB model
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Lapses in medication adherence over the last 7 and 30 days (self report) and over previous 12 months (pharmacy records).
Time Frame: 12 months
|
12 months
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Web service utilization.
Time Frame: 12 months
|
12 months
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Sheryl L. Catz, PhD, Kaiser Permanente
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
June 1, 2009
Primary Completion (Actual)
September 1, 2012
Study Completion (Actual)
September 1, 2012
Study Registration Dates
First Submitted
June 17, 2009
First Submitted That Met QC Criteria
June 17, 2009
First Posted (Estimate)
June 18, 2009
Study Record Updates
Last Update Posted (Actual)
October 13, 2017
Last Update Submitted That Met QC Criteria
October 11, 2017
Last Verified
October 1, 2017
More Information
Terms related to this study
Other Study ID Numbers
- 5R01MH081750 (U.S. NIH Grant/Contract)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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