Cardiopulmonary Resuscitation in Operating Room (CPR)

Intraoperative Cardiac Arrest: Incidence and Outcome

In the last ten years patient safety during routine surgical interventions has increased; however as there is an increase in the number of specialized surgical interventions and high risk patients like elderly and emergency patients, the incidence of perioperative cardiac arrest has not reduced but remains fixed. The incidence of perioperative cardiac arrest varies from 4.3-34.6 for each 10,000 procedures. However as in a lot of other countries exact data are lacking also for Turkey. With this study the investigators want to start collecting data about intraoperative cardiac arrest in Turkey, starting at their institution The aim is to evaluate the incidence and outcome in the study. Secondary aim is to assess the causes of cardiac arrest in the operating room.

Study Overview

• Status: Recruiting
• Conditions: Intraoperative Cardiac Arrest
• Intervention / Treatment: Procedure: cardiopulmonary resuscitation

Detailed Description

Patient information will be collected on a form entitled "Data collection form" including all medications and interventions during cardiopulmonary resuscitation and routine daily used anesthesia registration form.

• Study Type: Observational
• Enrollment (Estimated): 7

Contacts and Locations

• Study Contact: Name: Bahar Kuvaki, Professor; Phone Number: 902324122836; Email: bkuvaki@gmail.com
• Study Contact Backup: Name: Sule Ozbilgin, MD; Phone Number: 905055252901; Email: ozbilginsule@gmail.com

Study Locations

• Turkey
  • İzmir, Turkey, 35340
    • Recruiting
    • Dokuz Eylül University, School of Medicine, Department of Anesthesiology and Reanimation
    • Contact: Bahar Kuvaki, Professor; Phone Number: 902324122836; Email: bkuvaki@gmail.com
    • Contact: Sule Ozbilgin, MD; Phone Number: 905055252901; Email: ozbilginsule@gmail.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

This study will include all patients who develop cardiac arrest in the operating room (including preoperative waiting area and postoperative recovery unit) Dokuz Eylul University Hospital.

Description

Inclusion Criteria:

• All patients who develop cardiac arrest in the operating room

Exclusion Criteria:

• Absence of informed consent
• Patients arriving into the operating room with ongoing CPR

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Prospective

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
cardiac arrest group; patients who develop intraoperative cardiac arrest	Procedure: cardiopulmonary resuscitation; start cardiopulmonary resuscitation
without cardiac arrest group; patients who don't develop intraoperative cardiac arrest

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
incidence of intraoperative cardiac arrest	baseline
neurologic outcome of patients according to Cerebral performance category scale	until six months after return of spontaneous circulation

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
causes of intraoperative cardiac arrest among participants/patients	Probable causes of intraoperative cardiac arrest among participants/patients; Trauma; End stage liver disease and complications associated with liver transplantation; Unable to wean from cardiopulmonary bypass; Complications associated with cardiac surgery; Ruptured aneurysm; abdominal or thoracic; Technical complications: surgical and special procedures, central venous access; Complications associated with automatic implantable cardiac defibrillator placement; Hemorrhage; Complications associated with radical cancer surgery; Sepsis and multiple organ failure; Perioperative myocardial infarction; Complications associated with congenital heart defect; Complications associated with neurosurgery; Complications associated with Anaesthesia (anaphylaxis, difficult airway management/difficult ventilation, adverse drug, total spinal anaesthesia/bloc etc)	baseline

Collaborators and Investigators

• Sponsor: Dokuz Eylul University
• Investigators: Principal Investigator: Bahar Kuvaki, Professor, Dokuz Eylül University, School of Medicine, Department of Anesthesiology and Reanimation

Study record dates

Study Major Dates

• Study Start (Actual): March 1, 2016
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): May 1, 2027

Study Registration Dates

• First Submitted: August 17, 2016
• First Submitted That Met QC Criteria: August 29, 2016
• First Posted (Estimated): August 30, 2016

Study Record Updates

• Last Update Posted (Actual): February 20, 2024
• Last Update Submitted That Met QC Criteria: February 16, 2024
• Last Verified: February 1, 2024

More Information

Terms related to this study

• Keywords: CPR; cardiac arrest; operating room
• Additional Relevant MeSH Terms: Heart Diseases; Cardiovascular Diseases; Heart Arrest
• Other Study ID Numbers: 2482-GOA

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No