Compensatory Cognitive Training For Schizophrenia

Compensatory Cognitive Training for Psychosocial Correlates and Self-stigma in Persons With Schizophrenia

This study aimed to investigate the effects of compensatory cognitive training plus treatment as usual (CCT+TAU) versus treatment as usual (TAU) on on self-esteem, self-efficacy, quality of life, and self-stigma for schizophrenia.

Study Overview

• Status: Completed
• Conditions: Schizophrenia
• Intervention / Treatment: Behavioral: Compensatory Cognitive Training

• Study Type: Interventional
• Enrollment (Actual): 46
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Taiwan
  • Taoyuan, Taiwan, 330
    • Taoyuan Psychiatric Center Ministry of Health and Welfare

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 63 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Female

Description

Inclusion Criteria:

• diagnosis of schizophrenia, based on the ICD-10 diagnostic criteria for research (World Health Organization, 1992)
• age from 20 to 65
• attending day care center regularly for at least 3 months
• taking stable dose of medication for at least 3 months

Exclusion Criteria:

• comorbid autism spectrum disorder
• comorbid mental retardation
• lacking the reading and writing skills

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: CCT+TAU group; The participants in CCT+TAU group received compensatory cognitive training plus treatment as usual. The CCT intervention consisted of two 50-minute sessions each week for 10 weeks	Behavioral: Compensatory Cognitive Training; Teach the participants compensatory cognitive skills and strategies
No Intervention: TAU group; The participants in TAU group received usual treatment at the same time as CCT+TAU group.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change scores of Rosenberg Self-Esteem Scale (RSES)	The Chinese version of Rosenberg Self-Esteem Scale (RSES) was implemented as self-esteem measures. The total score ranged from 10 to 40, with higher scores reflecting higher levels of self-esteem.	3 times: 1 to 2 weeks before intervention, 1 day after intervention and at 1 month after intervention
Change scores of General Self-Efficacy Scale (GSES)	The Chinese version of General Self-Efficacy Scale (GSES) consisted of 10 items, assessing optimistic self-beliefs to cope with a variety of difficult demands in life. The total score ranged from 10 to 40, with higher scores indicating more self-efficacy.	3 times: 1 to 2 weeks before intervention, 1 day after intervention and at 1 month after intervention
Change scores of Schizophrenia Quality of Life Scale Revision 4 (SQLS-R4)	The Chinese version of Schizophrenia Quality of Life Scale Revision 4 (SQLS-R4) was administered to measure subjective quality of life. The total scores ranged from 33-165, with higher scores indicating comparatively lower quality of life.	3 times: 1 to 2 weeks before intervention, 1 day after intervention and at 1 month after intervention
Change scores of Internalized Stigma of Mental Illness (ISMIS)	The Chinese version of Internalized Stigma of Mental Illness (ISMIS) consists of 29 items incorporated in five domains: alienation, stereotype endorsement, discrimination experience, social withdrawal, and stigma resistance. The total scores range from 29-116. The higher scores on the ISMIS indicates more severe internalized stigmatization.	3 times: 1 to 2 weeks before intervention, 1 day after intervention and at 1 month after intervention

Collaborators and Investigators

• Sponsor: Taoyuan Psychiatric Center, Ministry of Health and Welfare, Executive Yuan, R.O.C. Taiwan

Study record dates

Study Major Dates

• Study Start (Actual): January 5, 2018
• Primary Completion (Actual): May 31, 2018
• Study Completion (Actual): May 31, 2018

Study Registration Dates

• First Submitted: July 26, 2019
• First Submitted That Met QC Criteria: July 30, 2019
• First Posted (Actual): August 1, 2019

Study Record Updates

• Last Update Posted (Actual): August 1, 2019
• Last Update Submitted That Met QC Criteria: July 30, 2019
• Last Verified: July 1, 2019

More Information

Terms related to this study

• Keywords: schizophrenia; compensatory cognitive training; generalized estimating equation; psychosocial correlates; self-stigma
• Additional Relevant MeSH Terms: Mental Disorders; Schizophrenia Spectrum and Other Psychotic Disorders; Schizophrenia
• Other Study ID Numbers: TaoyuanMH

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No