Effects of Motor Imagery on Autonomic Function

Effects of Motor Imagery on Autonomic Function and Motor Imagery Abilities in Healthy Individuals

Most studies on motor imagery suggested the effects of motor imagery are related to neuroplastic changes in the brain. In addition to that the neuroplastic changes, it is thought that motor imagery can alter metabolic responses just like in actual exercise. However, the level of evidence about the effect of motor imagery on autonomic functions is limited.

The aims of this study;

1. The primary aim of this study is to investigate the effects of activating and relaxing kinesthetic motor imagery on autonomic function in healthy individuals and to compare these two methods.
2. The secondary aim of this study is to explore the effects of these methods on motor imagery skills of individuals will also be investigated.

The participants will randomly be allocated into three groups: (1) Activating kinesthetic motor imagery training, (2) Relaxing kinesthetic motor imagery training, and (3) Control group.

Participants in the activating kinesthetic motor imagery training group will imagine high effort exercises (e.g. planking, boxing, jumping, squats, push-ups) in the sessions in home using the study audio-video motor imagery script. The relaxing kinesthetic motor imagery training group will imagine relaxing (low effort) exercises (e.g. breathing exercises, stretching, body awareness exercises) in home using the study audio-video motor imagery script. Prior the sessions, the participants will receive an introductory lecture about motor imagery. The intervention groups will practise 5 times per week for 17 minutes per day for 2 weeks. Phone calls will be performed for support and as a reminder for the assessment (after one week). The control group will receive no specific training. Data will be collected at baseline and after the two-week intervention by masked outcome assessors.

Study Overview

• Status: Completed
• Conditions: Motor Imagery Training
• Intervention / Treatment: Behavioral: Activating kinesthetic motor imagery training; Behavioral: Relaxing kinesthetic motor imagery training

• Study Type: Interventional
• Enrollment (Actual): 54
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey
  • İzmir, Turkey, 35620
    • İzmir Katip Çelebi University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 25 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Being healthy (not having any known chronic disease)
• Volunteer to participate in the study

Exclusion Criteria:

• Pregnancy
• Previous disorder/surgery history that can alter physical performance

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Activating kinesthetic motor imagery training	Behavioral: Activating kinesthetic motor imagery training; Participants in the activating kinesthetic motor imagery training group will imagine high effort exercises (e.g. planking, boxing, jumping, squats, push-ups) in the sessions in home using the study audio-video motor imagery script for 5 times per week; 17 min per day for 2 weeks. Phone calls will be performed for support and as a reminder for the assessment (after one week).
Active Comparator: Relaxing kinesthetic motor imagery training	Behavioral: Relaxing kinesthetic motor imagery training; Participants in the relaxing kinesthetic motor imagery training group will imagine relaxing (low effort) exercises (e.g. breathing exercises, stretching, body awareness exercises) in home using the study audio-video motor imagery script 5 times per week; 17 min per day for 2 weeks. Phone calls will be performed for support and as a reminder for the assessment (after one week).
No Intervention: Control (no specific intervention)

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Feasibility of the methods - minimum recruitment rate	A minimum recruitment rate of 10 participants per month will be accepted as feasiable.	through Study Completion, an Average of 8 Months
Feasibility of the methods - minimum retention rate	A target retention rate of 80% will be accepted as feasiable.	through Study Completion, an Average of 8 Months
Feasibility of the methods - minimum adherence rate	A target minimum adherence rate of 70% of the overall practice sessions will be accepted as feasiable.	through Study Completion, an Average of 8 Months
Feasibility of the methods - adverse events	A record sheet was prepared for possible adverse events during the tests and intervention. It includes information about seriousness, expectedness, severity, causality, time, duration of the event and clinical action taken. The numbers of adverse events will be reported.	through Study Completion, an Average of 8 Months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Edinburgh Handedness Inventory	The Edinburgh Handedness Inventory is a measurement scale used to assess the dominance of a person's right or left hand in everyday activities, sometimes referred to as laterality. The 10-item inventory contains a list of instructions to be carried out by the individual being assessed. Items are rated by direct observation of the individual's behavior or by self-report of everyday behavior. Scoring is as follows: "-50" always left, "-25" usually left, "0" no preference, "25" usually right, and "50" always right. Scores on the eight rows are summed to provide a score of -400 to +400. Positive scores indicate right-hand dominance and negative scores indicate left-hand dominance.	at Baseline
Movement Imagery Questionnaire-Revised	The Movement Imagery Questionnaire-Revised assesses visual and kinesthetic movement imagery ability and is comprised of four visual and four kinesthetic items. Each item entails performing a movement, visually or kinesthetically imaging that movement and then rating the ease or difficulty of generating that image on a 7-point scale from 1 = very hard to see/feel to 7 = very easy to see/feel. Higher scores indicate higher visual or kinesthetic movement imagery ability.	Change from Baseline at 2 Weeks
Mental chronometry for walking task	The participants will actually execute and imagine a motor task: walking at comfortable speed for a distance of 6 m. The duration of actual and imagined movements will be recorded by means of an electronic stopwatch. During the execution of the actual and imagined movements subjects will hold the electronic stopwatch in their non-dominant hand. They will start the stopwatch when they started to move (actual or imagined movement) and they will stop it when they completed their movement (actual or imagined). Delta time will be calculated with the formula [(actual - imagined) / (actual + imagined / 2)] × 100. Lower scores indicate higher motor imagery ability.	Change from Baseline at 2 Weeks
Mental chronometry for writing task	The participants will actually execute and imagine a motor task: writing the following sentence: "Türkiye'nin başkenti Ankara". The duration of actual and imagined movements will be recorded by means of an electronic stopwatch. During the execution of the actual and imagined movements subjects will hold the electronic stopwatch in their non-dominant hand. They will start the stopwatch when they started to move (actual or imagined movement) and they will stop it when they completed their movement (actual or imagined). Delta time will be calculated with the formula [(actual - imagined) / (actual + imagined / 2)] × 100. Lower scores indicate higher motor imagery ability.	Change from Baseline at 2 Weeks
Hand Laterality Judgement Measurement	A tablet including an application Recognise™ app, NOI) will be placed on a table while the participants sitting in a standard chair. When given the cue to begin, participants will view the image and touch the screen to select the appropriate hand laterality judgement image interpretation. A standard 5-s maximum time limit per image will be set on the app. At the completion of the 40 images the accuracy for right, left, and total will be recorded along with average time per image to the nearest hundredth of a second.	Change from Baseline at 2 Weeks
Resting Metabolic Rate Measurements - Oxygen Consumption	Quark cardiopulmonary exercise testing system will be used to assess Resting Metabolic Rate Measurements. Oxygen consumption is an indicator of aerobic capacity. Higher scores indicate higher aerobic capacity.	Change from Baseline at 2 Weeks
Resting Metabolic Rate Measurements - Respiratory Exchange Ratio	Quark cardiopulmonary exercise testing system will be used to assess Resting Metabolic Rate Measurements. The ratio of carbon dioxide output/oxygen uptake is called the respiratory exchange ratio. Under steady state conditions, the respiratory exchange ratio equals the respiratory quotient. The respiratory quotient value is determined by the fuels used for metabolic processes. An respiratory quotient of 1 indicates metabolism primarily of carbohydrates, whereas an respiratory quotient of <1 indicates a mixture of carbohydrates and fat (respiratory quotient about 0.7) or protein (respiratory quotient about 0.8).	Change from Baseline at 2 Weeks

Collaborators and Investigators

• Sponsor: Izmir Katip Celebi University

Study record dates

Study Major Dates

• Study Start (Actual): November 21, 2019
• Primary Completion (Actual): March 31, 2020
• Study Completion (Actual): March 31, 2020

Study Registration Dates

• First Submitted: November 18, 2019
• First Submitted That Met QC Criteria: November 19, 2019
• First Posted (Actual): November 20, 2019

Study Record Updates

• Last Update Posted (Actual): February 17, 2021
• Last Update Submitted That Met QC Criteria: February 16, 2021
• Last Verified: February 1, 2021

More Information

Terms related to this study

• Other Study ID Numbers: 2019-GOKAE-1150

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: Undecided

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No