- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04215679
Effect of Motor Imagery With Virtual Reality in Patients With Stroke
Comparison of Three Dimensional Virtual Reality Therapy and Motor Imaging in Functional Recovery of Upper Extremity After Stroke
Study Overview
Status
Conditions
Detailed Description
Although the effects of non-three-dimensional virtual reality and motor imagination on the brain have been investigated in a study, such comparison has not been made between the three-dimensional virtual reality and motor imagery.
Considering these situations, the aim of this study is to compare the effect of three-dimensional (immersive) virtual reality and motor imagery on upper extremity functional recovery after stroke.
Study Type
Enrollment (Estimated)
Phase
- Not Applicable
Contacts and Locations
Study Contact
- Name: Şebnem AVCI, Ph.D
- Phone Number: +905057811059
- Email: avciseb@hotmail.com
Study Contact Backup
- Name: Ramazan Kurul, Ph.D
- Phone Number: +905436414731
- Email: ramazankurul2@hotmail.com
Study Locations
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Merkez
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Bolu, Merkez, Turkey, 14100
- Recruiting
- Abant Izzet Baysal University
-
Principal Investigator:
- Muhammed Nur Öğün, M.D.
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Principal Investigator:
- Şebnem Avcı, Ph.D
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Contact:
- Ramazan Kurul, Ph.D
- Phone Number: +905436414731
- Email: ramazankurul2@hotmail.com
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Contact:
- Muhammed Nur ÖĞÜN, M.D
- Phone Number: +905072329466
- Email: dr.mogun@gmail.com
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Principal Investigator:
- Ramazan Kurul, Ph.D
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Description
Inclusion Criteria:
- Diagnosed as stroke patient.
- Speaks, reads and writes in Turkish.
- Hand functions at 4, 5, 6 levels according to Brunnstrom.
- Mini mental test score to be at least 24.
- Volunteer for participation.
Exclusion Criteria:
- Neurological, orthopedic problems other than stroke.
- To have motion sickness that cannot continue 3D application.
- Individuals neglecting the affected side
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Three-dimensional immersive virtual reality application
25 stroke patients between the ages of 18-80, stroke duration of less than 2 months and not more than 2 years whose mini Mental State Examination (MMSE) scores equal or above the 25 will be included in this study.
Oculus Rift and Leap motion will be used to create an immersive interactive environment.
Modified Ashworth Scale (MAS), Functional independence scale, self-care questionnaire,Action Research Arm Test, Fugl meyer upper extremity motor evaluations will be applied just before the rehabilitation program, after the application and at the end of 6 weeks.
|
In this group, individuals will be included in a game program that will last for 3 days a week for a total of 6 weeks and 45 minutes a day.
Individuals will use the IVR to rehabilitate functions that are frequently used in daily life through task-oriented games.
The IVR device will be placed on the head of the individual by closing the eyes of the individual and the Leap Motion device will be used to enable individuals to see their own hands in a virtual reality environment.
In order to ensure the safety of individuals, practices shall be carried out with the individual sitting in the chair and leaning against the back.
A total of 3 different games will be used for upper extremity function, each game will be 15 minutes and the total session time will be 45 minutes.
|
Active Comparator: Motor imagery
25 stroke patients between the ages of 18-80, stroke duration of less than 2 months and not more than 2 years whose MMSE scores equal or above the 25 will be included in this study.
Oculus Rift and Leap motion will be used to create an immersive interactive environment.
Modified Ashworth Scale (MAS), Functional independence scale, self-care questionnaire,Action Research Arm Test, Fugl meyer upper extremity motor evaluations will be applied just before the rehabilitation program, after the application and at the end of 6 weeks.
|
Motor imagery will be performed with the eyes closed.
In addition, for the safety of the individual, the individual will sit comfortably in a chair in a quiet environment and sit back.
In the motor imagery group, individuals will be shown videos of the 3 games for 2 times in the IVR group and will be asked to imagine that they perform the same functions in the IVR games.
The motor imagery will be 3 days a week for a total of 6 weeks and 45 minutes per day (including rest periods).
|
Active Comparator: Conventional physiotherapy
25 stroke patients between the ages of 18-80, stroke duration of less than 2 months and not more than 2 years whose MMSE scores equal or above the 25 will be included in this study.
Oculus Rift and Leap motion will be used to create an immersive interactive environment.
Modified Ashworth Scale (MAS), Functional independence scale, self-care questionnaire,Action Research Arm Test, Fugl meyer upper extremity motor evaluations will be applied just before the rehabilitation program, after the application and at the end of 6 weeks.
|
Individuals in this group will be randomly recruited from hospitalized stroke volunteers.
Since these individuals receive routine rehabilitation 5 days a week, they will be evaluated at the beginning and end of 18 sessions over a total period of 6 weeks.
Conventional physiotherapy will include normal joint movements, muscle strengthening exercises, balance and mobility exercises, and exercises to improve daily life activity.
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Jebsen Hand Function Test
Time Frame: 6 weeks
|
The test consists of 7 subtitles and is an objective and standardized test.
The test consists of 7 subtitles: "writing a standard sentence", "flipping 5 cards", "picking up small objects", "feeding simulation", "arranging backgammon checkers", "carrying large light objects" and "carrying large heavy objects".
The score of the test is the completion time of the test and is recorded in seconds
|
6 weeks
|
Action Reach Arm Test (ARAT)
Time Frame: 6 weeks
|
This scale is scored between 0-57 points and consists of 4 headings: gross grip, fine grip, fingertip grip, and gross motion.
Each part is calculated over 3 points.
3 points mean that the test is done in a normal way, 2 points show the difficulty and abnormally long time for doing it, 1 point means that individual can partially complete the test and 0 points can not complete the test.
The higher the score, the better the level.
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6 weeks
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Stroke impact scale (SIS)
Time Frame: 6 weeks
|
Turkish validity was done by Hantal et al. in 2014.
It is a 9-stage scale that is scored between 0-57 points, with a higher score indicating a better condition and a lower score indicating a higher severity of stroke.
Scoring is done separately for each title
|
6 weeks
|
Kinesthetic and visual imagery questionnaire
Time Frame: 6 weeks
|
It was developed in 2007 by Malouin et al.
In this method, the participant is told about the desired movement and is asked to do so.
Then the participant is asked to imagine as if he was watching the movement without making any movement.
It is scored between 1-5 points.
1: no image, 5: as clear as the original.
At the other stage, he is asked to imagine himself by feeling what he is doing and is scored between 1 and 5 points. 1 point: no sense, 5 points mean intense feeling as if he is making the move.
The scale assesses both visual and kinesthetic imagery with each dimension being scored from 5 to 25 with higher scores indicating greater imagery clarity or intensity.
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6 weeks
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Muhammed Nur Ögün, MD, Bolu Abant Izzet Baylsa University
- Study Director: Şebnem AVCI, Ph.D, Bolu Abant Izzet Baylsa University
- Principal Investigator: Mustafa Fatih Yaşar, MD, Bolu Abant Izzet Baylsa University
- Principal Investigator: Ramazan KURUL, Ph.D, Bolu Abant Izzet Baylsa University
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- AIBU-FTR-RK-05
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
product manufactured in and exported from the U.S.
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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