Eine Studie zur Wirksamkeit und Sicherheit von Upadacitnib (ABT-494) bei Teilnehmern mit mäßig bis schwermbus Mor Crohn, unzureichend auf konventionelle und/oder biologische Therapien angesprochen haben oder diese nicht vertragen

Eine multizentrische, randomisierte, doppelblinde, placebokontrollierte Induktionsstudie zur Wirksamkeit und Sicherheit von Upadacitinib (ABT-494) bei Patienten mit mäßig bis schwer aktivem Morbus Crohn, die unzureichend auf konventionelle und/oder biologische Therapien angesprochen haben oder diese nicht vertragen

Sponsoren

Hauptsponsor: AbbVie

Quelle AbbVie
Kurze Zusammenfassung

Das Ziel dieser Studie ist es, die Wirksamkeit und Sicherheit von Upadacitinib im Vergleich zu Placebo als Induktionstherapie bei Teilnehmern mit mäßig und schwer aktivem Morbus Crohn Krankheit (CD).

Gesamtstatus Rekrutierung
Anfangsdatum 2017-12-07
Fertigstellungstermin 2022-02-02
Primäres Abschlussdatum 2021-09-14
Phase Phase 3
Studientyp Interventionell
Primärer Ausgang
Messen Zeitfenster
Percentage of Participants with Clinical Remission per Crohn's Disease Activity Index (CDAI) Week 12
Prozentsatz der Teilnehmer mit endoskopischer Reaktion Woche 12
Sekundäres Ergebnis
Messen Zeitfenster
Percentage of Participants with Clinical Remission per Patient-Reported Outcomes (PROs) Week 12
Prozentsatz der Teilnehmer mit endoskopischer Remission Woche 12
Prozentsatz der Teilnehmer, die die Anwendung von Kortikosteroiden bei Morbus Crohn (CD) abbrechen und eine klinische Remission gemäß dem Aktivitätsindex für Morbus Crohn (CDAI) erreichen, bei Teilnehmern, die zu Studienbeginn Kortikosteroide einnehmen. Woche 12
Änderung der funktionellen Bewertung der chronischen Krankheitstherapie-Müdigkeit (FACIT-F) Baseline (Woche 0) bis Woche 12
Änderung des Fragebogens zu chronisch entzündlichen Darmerkrankungen (IBDQ) Baseline (Woche 0) bis Woche 12
Prozentsatz der Teilnehmer mit klinischem Ansprechen 100 (CR-100) Bis Woche 12
Prozentsatz der Teilnehmer mit klinischer Remission nach Morbus Crohn-Aktivitätsindex (CDAI) Woche 4
Prozentsatz der Teilnehmer mit Krankenhausaufenthalten aufgrund von Morbus Crohn (CD) Woche 12
Prozentsatz der Teilnehmer mit Auflösung der extraintestinalen Manifestation (EIMs) an Teilnehmern mit EIMs zu Studienbeginn Woche 12
Einschreibung 501
Bedingung
Intervention

Interventionsart: Drug

Interventionsname: Upadacitinib

Beschreibung: Oral; Tablet

Interventionsart: Arzneimittel

Interventionsname: Placebo für Upadacitinib

Beschreibung: Oral; Tablette

Armgruppenetikett: Arm B: Placebo und Upadacitinib

Teilnahmeberechtigung

Kriterien:

Einschlusskriterien: - Bestätigte Diagnose von CD für mindestens 3 Monate vor Baseline. - Bestätigte Diagnose einer mittelschweren bis schweren CD anhand der Stuhlfrequenz (SF), Bauchschmerzen (AP)-Score. - Nachweis einer Schleimhautentzündung basierend auf dem vereinfachten endoskopischen Score für Morbus Crohn Krankheit (SES-CD) auf einer von einem zentralen Lesegerät bestätigten Endoskopie. - eine unzureichende Reaktion oder Intoleranz auf eine oder mehrere konventionelle und/oder biologische Therapien (Orale lokal wirkende Steroide, intravenöse oder orale Kortikosteroide, Immunsuppressiva), nach Ansicht des Prüfarztes. Hinweis: Teilnehmer, die auf eine konventionelle Therapie unzureichend angesprochen oder diese nicht vertragen haben die bereits Biologika erhalten haben, können eingeschrieben werden; Teilnehmer müssen jedoch haben das Biologikum aus anderen Gründen als unzureichendem Ansprechen oder Unverträglichkeit (z. Versicherungswechsel, gut kontrollierte Krankheit). - Wenn weiblich, muss die Teilnehmerin die Verhütungsempfehlungen erfüllen. Ausschlusskriterien: - Teilnehmer mit einer aktuellen Diagnose von Colitis ulcerosa oder Colitis unbestimmt. - Teilnehmer, der keine stabilen Dosen von CD-bezogenen Antibiotika, oralen Aminosalicylaten, Kortikosteroide oder Methotrexat (MTX). - Teilnehmer mit den folgenden anhaltenden bekannten Komplikationen der Zöliakie: Abszess (abdominale oder perianal), symptomatische Darmstrikturen, fulminante Kolitis, toxisches Megakolon oder jede andere Manifestation, die während der Teilnahme an der Studie eine Operation erfordern könnte. - Teilnehmer mit Stoma- oder Ileoanalbeutel. - Bei dem Teilnehmer wurden Erkrankungen diagnostiziert, die die Arzneimittelaufnahme beeinträchtigen könnten einschließlich, aber nicht beschränkt auf Kurzdarm- oder Kurzdarmsyndrom. - Screening-Labor und andere Analysen zeigen abnormale Ergebnisse.

Geschlecht:

Alle

Mindestalter:

18 Jahre

Maximales Alter:

75 Jahre

Gesunde Freiwillige:

Nein

Insgesamt offiziell
Nachname Rolle Zugehörigkeit
ABBVIE INC. Study Director AbbVie
Gesamtkontakt

Nachname: ABBVIE CALL CENTER

Telefon: 844-663-3742

Email: [email protected]

Ort
Einrichtung: Status:
East View Medical Research, LLC /ID# 171176 | Mobile, Alabama, 36606, United States Recruiting
CB Flock Research Corporation /ID# 166185 | Mobile, Alabama, 36608, United States Recruiting
Delsol Research Management, Ll /Id# 170145 | Chandler, Arizona, 85224, United States Completed
HonorHealth Research Institute - Shea /ID# 164821 | Scottsdale, Arizona, 85258, United States Recruiting
Arizona Arthritis & Rheumatology Research, PLLC /ID# 164803 | Sun City, Arizona, 85306, United States Recruiting
Southern California Res. Ctr. /ID# 169655 | Coronado, California, 92118-1408, United States Active, not recruiting
Citrus Valley Gastroenterology /ID# 166173 | Covina, California, 91722-3797, United States Recruiting
Hoag Memorial Hosp Presbyterian /ID# 222540 | Irvine, California, 92618, United States Recruiting
United Medical Doctors /ID# 207449 | Los Alamitos, California, 90720-3309, United States Recruiting
Gastrointestinal Biosciences Clinical Trials, LLC /ID# 164762 | Los Angeles, California, 90067-2001, United States Completed
Facey Medical Foundation /ID# 203136 | Mission Hills, California, 91345, United States Recruiting
United Medical Doctors - Murrieta /ID# 164945 | Murrieta, California, 92563, United States Recruiting
Ucsd /Id# 164910 | San Diego, California, 92103, United States Recruiting
Medical Assoc Research Grp /ID# 169706 | San Diego, California, 92123, United States Recruiting
Univ of California San Francis /ID# 164944 | San Francisco, California, 94158, United States Recruiting
Care Access Research /ID# 167767 | San Pablo, California, 94806, United States Completed
Peak Gastroenterology Associates, PC /ID# 170143 | Colorado Springs, Colorado, 80907, United States Recruiting
Delta Waves, Inc. /ID# 164776 | Colorado Springs, Colorado, 80918, United States Recruiting
Western States Clinical Res /ID# 164760 | Wheat Ridge, Colorado, 80033-2896, United States Recruiting
Medical Research Center of CT /ID# 164926 | Hamden, Connecticut, 06518, United States Recruiting
Clinical Research of West Florida, Inc /ID# 205827 | Clearwater, Florida, 33765, United States Completed
Clinical Research of West Florida, Inc /ID# 208118 | Clearwater, Florida, 33765, United States Completed
Advanced Research - Coral Springs /ID# 218021 | Coral Springs, Florida, 33067-3173, United States Recruiting
Encore Borland-Groover Clinical Research /Id# 203499 | Jacksonville, Florida, 32256, United States Recruiting
Ctr for Advanced Gastroenterol /ID# 165353 | Maitland, Florida, 32751-6108, United States Recruiting
Crystal Pharmacology Research /ID# 166081 | Miami, Florida, 33165, United States Completed
Coral Research Clinic /ID# 164890 | Miami, Florida, 33186-4643, United States Recruiting
Advanced Research Institute, Inc /ID# 164921 | New Port Richey, Florida, 34653, United States Recruiting
Endoscopic Research, Inc. /ID# 206136 | Orlando, Florida, 32803, United States Recruiting
Omega Research Consultants /ID# 203481 | Orlando, Florida, 32810, United States Recruiting
Clinical Research Trials of Florida, Inc. /ID# 203485 | Tampa, Florida, 33607, United States Completed
AdventHealth Tampa /ID# 171167 | Tampa, Florida, 33613-4680, United States Completed
Gastroenterology Associates of Central Georgia, LLC /ID# 165478 | Macon, Georgia, 31201, United States Recruiting
Gastroenterology Consultants PC - Roswell /ID# 218220 | Roswell, Georgia, 30076-4913, United States Recruiting
Atlanta Gastroenterology Spec /ID# 164799 | Suwanee, Georgia, 30024, United States Recruiting
Treasure Valley Medical Research /ID# 215032 | Boise, Idaho, 83706, United States Completed
Rush University Medical Center /ID# 165497 | Chicago, Illinois, 60612, United States Recruiting
University of Chicago Medicine /ID# 165503 | Chicago, Illinois, 60637-1426, United States Recruiting
DuPage Medical Group /ID# 205328 | Downers Grove, Illinois, 60515-5509, United States Recruiting
MediSphere Medical Research Center /ID# 166175 | Evansville, Indiana, 47714-8011, United States Recruiting
Indianapolis Gastroenterology /ID# 164938 | Indianapolis, Indiana, 46237, United States Recruiting
University of Iowa Hospitals and Clinics /ID# 165436 | Iowa City, Iowa, 52242, United States Completed
Tri-State Gastroenterology /ID# 165496 | Crestview Hills, Kentucky, 41017, United States Recruiting
University of Louisville /ID# 165366 | Louisville, Kentucky, 40202, United States Recruiting
University of Louisville /ID# 168572 | Louisville, Kentucky, 40202, United States Recruiting
CroNOLA, LLC /ID# 164823 | Houma, Louisiana, 70360, United States Completed
Nola Research Works, LLC /ID# 164759 | New Orleans, Louisiana, 70115, United States Recruiting
Louisana Research Center, LLC /ID# 164894 | Shreveport, Louisiana, 71105-6800, United States Recruiting
Johns Hopkins University School of Medicine /ID# 211941 | Baltimore, Maryland, 21287-0010, United States Recruiting
MGG Group Co, Inc.Chevy Chase Clinical Research /ID# 164935 | Chevy Chase, Maryland, 20815, United States Recruiting
Gastro Center of Maryland /ID# 171161 | Columbia, Maryland, 21045, United States Recruiting
Lahey Hospital and Medical Center /ID# 214726 | Burlington, Massachusetts, 01805, United States Recruiting
University of Michigan Health Systems /ID# 164943 | Ann Arbor, Michigan, 48109, United States Recruiting
Clin Res Inst of Michigan, LLC /ID# 170133 | Chesterfield, Michigan, 48047, United States Recruiting
Digestive Health Associates (DHA) - Farmington Hills /ID# 205793 | Farmington Hills, Michigan, 48334-3230, United States Completed
Center for Digestive Health /ID# 164822 | Troy, Michigan, 48098-6363, United States Recruiting
Mayo Clinic /ID# 164783 | Rochester, Minnesota, 55905-0001, United States Recruiting
Southern Therapy and Advanced Research (STAR) LLC /ID# 165343 | Jackson, Mississippi, 39216, United States Recruiting
Quality Clinical Research, Inc /ID# 170137 | Omaha, Nebraska, 68114, United States Recruiting
CHI Nebraska d/b/a CHI Health /ID# 168578 | Omaha, Nebraska, 68124, United States Recruiting
Las Vegas Medical Research /ID# 168588 | Las Vegas, Nevada, 89113, United States Recruiting
AGA Clinical Research Associates, LLC /ID# 164769 | Egg Harbor Township, New Jersey, 08234, United States Recruiting
Rutgers Robert Wood Johnson /ID# 166073 | New Brunswick, New Jersey, 08901, United States Recruiting
Montefiore Medical Center - Moses Campus /ID# 166193 | Bronx, New York, 10467, United States Completed
Advantage Clinical Trials /ID# 168546 | Bronx, New York, 10468, United States Active, not recruiting
NY Scientific /ID# 164931 | Brooklyn, New York, 11235, United States Recruiting
United Health Services Hospitals, Inc /ID# 217485 | Johnson City, New York, 13790-2107, United States Recruiting
NYU Langone Long Island Clinical Research Associates /ID# 164927 | Lake Success, New York, 11042, United States Recruiting
The Mount Sinai Hospital /ID# 170257 | New York, New York, 10029, United States Recruiting
Columbia Univ Medical Center /ID# 164782 | New York, New York, 10032-3725, United States Completed
Gastro Group of Rochester /ID# 166177 | Rochester, New York, 14618-5703, United States Recruiting
Richmond University Medical Center /ID# 201857 | Staten Island, New York, 10310-1664, United States Completed
Atrium Health Carolinas Medical Center /ID# 164932 | Charlotte, North Carolina, 28203, United States Recruiting
PMG Research of Charlotte /ID# 171160 | Charlotte, North Carolina, 28209, United States Recruiting
Wake Radiology UNC REX Healthcare - Raleigh Office /ID# 164904 | Raleigh, North Carolina, 27612, United States Completed
Wake Forest Baptist Medical Center /ID# 164908 | Winston-Salem, North Carolina, 27157-0001, United States Recruiting
Plains Clinical Research Center, LLC /ID# 170140 | Fargo, North Dakota, 58104-5925, United States Recruiting
Consultants for Clinical Res /ID# 164791 | Cincinnati, Ohio, 45219, United States Completed
University of Cincinnati /ID# 164825 | Cincinnati, Ohio, 45267-0585, United States Recruiting
Cleveland Clinic Main Campus /ID# 209231 | Cleveland, Ohio, 44195, United States Recruiting
The Ohio State University /ID# 170141 | Columbus, Ohio, 43210, United States Recruiting
Optimed Research, Ltd. /ID# 205624 | Columbus, Ohio, 43235, United States Recruiting
Hometown Urgent Care and Resea /ID# 201291 | Dayton, Ohio, 45424, United States Completed
Dayton Gastroenterology, Inc. /ID# 167627 | Englewood, Ohio, 45415, United States Active, not recruiting
Great Lakes Gastroenterology Research LLC /ID# 202010 | Mentor, Ohio, 44060-6211, United States Completed
Digestive Disease Specialists /ID# 201064 | Oklahoma City, Oklahoma, 73112, United States Recruiting
Options Health Research, LLC /ID# 164820 | Tulsa, Oklahoma, 74104, United States Recruiting
Healthcare Research Consultant /ID# 166195 | Tulsa, Oklahoma, 74135, United States Completed
University of Pennsylvania /ID# 168430 | Philadelphia, Pennsylvania, 19104-5502, United States Recruiting
Pharmacorp Clinical Trials /ID# 164916 | Charleston, South Carolina, 29412, United States Recruiting
Gastroenterology Associates, P.A. of Greenville /ID# 164771 | Greenville, South Carolina, 29615-3593, United States Recruiting
Rapid City Medical Center - GI Research /ID# 201735 | Rapid City, South Dakota, 57701, United States Recruiting
Gastro One /ID# 164826 | Germantown, Tennessee, 38138, United States Recruiting
East Tennessee Research Institute /ID# 203613 | Johnson City, Tennessee, 37604, United States Recruiting
Quality Medical Research /ID# 205263 | Nashville, Tennessee, 37211, United States Completed
Vanderbilt University Medical Center /ID# 164946 | Nashville, Tennessee, 37232-0011, United States Active, not recruiting
TX Clinical Research Institute /ID# 164896 | Arlington, Texas, 76012, United States Recruiting
Quest Clinical Research /ID# 164785 | Baytown, Texas, 77521-2415, United States Active, not recruiting
Texas Digestive Disease Consultants /ID# 209801 | Cedar Park, Texas, 78613-5028, United States Recruiting
Texas Digestive Disease Consultants /ID# 209953 | Cedar Park, Texas, 78613-5028, United States Recruiting
Baylor Scott & White Center for Inflammatory Bowel Diseases /ID# 170144 | Dallas, Texas, 75246, United States Recruiting
CliniCore International, LLC /ID# 164902 | Houston, Texas, 77027-6812, United States Completed
Baylor College of Medicine - Baylor Medical Center /ID# 164947 | Houston, Texas, 77030-3411, United States Recruiting
Centex Studies, Inc. - Houston /ID# 201214 | Houston, Texas, 77058, United States Recruiting
GI Specialists of Houston /ID# 202339 | Houston, Texas, 77070-4347, United States Completed
Caprock Gastro Research /ID# 215438 | Lubbock, Texas, 79424-3017, United States Recruiting
Clinical Associates in Research Therapeutics of America, LLC /ID# 164786 | San Antonio, Texas, 78212, United States Recruiting
Southern Star Research Institute, LLC /ID# 169755 | San Antonio, Texas, 78229-5390, United States Recruiting
Carl R. Meisner Medical Clinic /ID# 201061 | Sugar Land, Texas, 77478, United States Completed
Tyler Research Institute, LLC /ID# 168687 | Tyler, Texas, 75701-4464, United States Recruiting
Gastro Health & Nutrition - Victoria /ID# 167812 | Victoria, Texas, 77904, United States Recruiting
HP Clinical Research /ID# 164933 | Bountiful, Utah, 84010, United States Completed
Advanced Research Institute /ID# 164784 | Ogden, Utah, 84403, United States Completed
Care Access Research /ID# 164794 | Salt Lake City, Utah, 84124-1377, United States Completed
Velocity Clinical Research/ Gut Whisperer /ID# 166076 | West Jordan, Utah, 84088, United States Recruiting
Washington Gastroenterology Associates /ID# 164824 | Bellevue, Washington, 98004, United States Active, not recruiting
Virginia Mason - Seattle Orthapedics /ID# 164913 | Seattle, Washington, 98101, United States Recruiting
The Vancouver Clinic, INC. PS /ID# 164918 | Vancouver, Washington, 98664, United States Active, not recruiting
Allegiance Research Specialist /ID# 165346 | Wauwatosa, Wisconsin, 53226, United States Recruiting
Cemic /Id# 169182 | Ciudad Autonoma de Buenos Aire, Buenos Aires, 1431, Argentina Recruiting
Cardio Alem /ID# 211285 | San Isidro, Buenos Aires, 1642, Argentina Recruiting
Hospital Italiano de Buenos Aires /ID# 215541 | Ciudad Autonoma de Buenos Aire, Ciuadad Autonoma De Buenos Aires, 1199, Argentina Recruiting
Gedyt /ID# 210020 | Ciudad Autonoma de Buenos Aire, Ciuadad Autonoma De Buenos Aires, 1426, Argentina Recruiting
Hospital Centenario /Id# 171252 | Rosario, Santa Fe, 2000, Argentina Recruiting
Hospital Privado Univesitario /ID# 169230 | Cordoba, 5016, Argentina Recruiting
Concord Repatriation General Hospital /ID# 171512 | Concord, New South Wales, 2139, Australia Recruiting
Coral Sea Clinical Research institute /ID# 212988 | North Mackay, Queensland, 4740, Australia Active, not recruiting
Mater Misericordiae Limited /ID# 204909 | South Brisbane, Queensland, 4101, Australia Recruiting
Royal Adelaide Hospital /ID# 171514 | Adelaide, South Australia, 5000, Australia Active, not recruiting
Box Hill Hospital /ID# 203736 | Box Hill, Victoria, 3128, Australia Active, not recruiting
Fiona Stanley Hospital /ID# 171513 | Murdoch, Western Australia, 6150, Australia Recruiting
Medical University of Vienna /ID# 169465 | Vienna, Wien, 1090, Austria Completed
LKH Salzburg and Paracelsus /ID# 214470 | Salzburg, 5020, Austria Completed
UCL Saint-Luc /ID# 200303 | Woluwe-Saint-Lambert, Bruxelles-Capitale, 1200, Belgium Recruiting
CHU de Liege Sart Tilman /ID# 217534 | Liège, Liege, 4000, Belgium Recruiting
AZ Sint-Lucas /ID# 200302 | Gent, 9000, Belgium Recruiting
University Clinical Centre of the Republic of Srpska /ID# 208051 | Banja Luka, Republika Srpska, 78000, Bosnia and Herzegovina Recruiting
University Clinical Center Tuzla /ID# 210325 | Tuzla, Tuzlanski, 75000, Bosnia and Herzegovina Recruiting
Clinical Center University of Sarajevo /ID# 203887 | Sarajevo, 71000, Bosnia and Herzegovina Recruiting
Polyclinic and Daily Hospital Dr. Al-Tawil /ID# 217842 | Sarajevo, 71000, Bosnia and Herzegovina Recruiting
Instituto Goiano de Gastroenterologia e Endoscopia Digestiva /ID# 166852 | Goiania, Goias, 74535-170, Brazil Completed
Hospital Nossa Senhora das Graças /ID# 166863 | Curitiba, Parana, 80810-040, Brazil Recruiting
Hospital de Clinicas de Porto Alegre /ID# 166862 | Porto Alegre, Rio Grande Do Sul, 90035-903, Brazil Recruiting
Upeclin Fmb - Unesp /Id# 166867 | Botucatu, Sao Paulo, 18618-686, Brazil Recruiting
Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto - USP /ID# 166866 | Ribeirão Preto, Sao Paulo, 14051-140, Brazil Recruiting
Faculdade de Medicina do ABC /ID# 208323 | Santo André, Sao Paulo, 09060-870, Brazil Recruiting
Kaiser Clinica e Hospital Dia /ID# 166865 | Sao Jose Do Rio Preto, Sao Paulo, 15015-110, Brazil Recruiting
UMHAT Kaspela EOOD /ID# 167613 | Plovdiv, 4001, Bulgaria Recruiting
Second MHAT Sofia /ID# 167614 | Sofia, 1202, Bulgaria Completed
MHAT Trakia /ID# 201679 | Stara Zagora, 6004, Bulgaria Completed
University of Calgary - Cumming School of Medicine - Adult Cystic Fibrosis Clini /ID# 166974 | Calgary, Alberta, T2N 4Z6, Canada Recruiting
Allen Whey Khye Lim Professional Corporation /ID# 168044 | Edmonton, Alberta, T5R 1W2, Canada Recruiting
University of Alberta - Zeidler Ledcor Centre /ID# 166971 | Edmonton, Alberta, T6G 2X8, Canada Recruiting
Covenant Health /ID# 166978 | Edmonton, Alberta, T6K 4B2, Canada Recruiting
Fraser Clinical Trials Inc /ID# 166968 | New Westminster, British Columbia, V3L 3W4, Canada Recruiting
GIRI Gastrointestinal Research Institute /ID# 166975 | Vancouver, British Columbia, V6Z 2K5, Canada Recruiting
QEII - Health Sciences Centre /ID# 169307 | Halifax, Nova Scotia, B3H 2Y9, Canada Recruiting
London Health Sciences Center /ID# 221038 | London, Ontario, N6A 5W9, Canada Recruiting
Scott Shulman Medicine Professional Corporation /ID# 169066 | North Bay, Ontario, P1B 2H3, Canada Recruiting
Taunton Surgical Centre /ID# 168043 | Oshawa, Ontario, L1H 7K4, Canada Recruiting
The Ottawa Hospital /ID# 212414 | Ottawa, Ontario, K1H 8L6, Canada Recruiting
Medicor Research Inc /ID# 166979 | Sudbury, Ontario, P3A 1W8, Canada Recruiting
Toronto Digestive Disease Asso /ID# 166972 | Vaughan, Ontario, L4L 4Y7, Canada Recruiting
CHAU- Hotel-Dieu de Levis /ID# 166969 | Levis, Quebec, G6V 3Z1, Canada Recruiting
Crchum /Id# 170120 | Montreal, Quebec, H2X 0A9, Canada Recruiting
Montreal General Hospital - McGill University Health Center /ID# 170119 | Montreal, Quebec, H3G 1A4, Canada Completed
CIUSSS de l'Estrie - CHUS /ID# 170940 | Sherbrooke, Quebec, J1G 2E8, Canada Recruiting
Research Group /ID# 203179 | Santiago, Region Metropolitana De Santiago, 2540364, Chile Recruiting
M y F Estudios Clínicos /ID# 169984 | Santiago, Region Metropolitana De Santiago, 7750495, Chile Recruiting
Hospital Guillermo Grant Benavente de Concepción /ID# 212423 | Concepción, 4070038, Chile Recruiting
CTR Estudios Clinicos /ID# 203941 | Providencia, 7500571, Chile Recruiting
Hospital Clinico Universidad De Los Andes /ID# 207466 | Santiago, 7501504, Chile Recruiting
Zhongshan Hospital Xiamen University /ID# 204984 | Fujian, Anhui, 361004, China Recruiting
Sun Yat-sen Memorial Hospital of Sun Yat-sen University /ID# 205228 | Guangzhou, Guangdong, 510120, China Recruiting
The Sixth Affiliated Hosp Sun /ID# 204077 | Guangzhou, Guangdong, 510655, China Recruiting
Tongji Medical College Huazhong Univ of Science and Techno /ID# 204081 | Wuhan, Hubei, 430022, China Recruiting
The First Affiliated Hospital of Nanchang University /ID# 204092 | Nanchang, Jiangxi, 330006, China Recruiting
The First Hospital of Jilin University /ID# 206868 | Changchun, Jilin, 130021, China Completed
Ruijin Hospital, Shanghai Jiaotong University School of Medicine /ID# 204091 | Shanghai, Shanghai, 200025, China Recruiting
The second Affiliated hospital of Zhejiang University school of Medicine /ID# 204073 | Hangzhou, Zhejiang, 310009, China Recruiting
Sir Run Run Shaw Hospital /ID# 204076 | Hangzhou, Zhejiang, 310018, China Recruiting
Beijing Friendship Hospital /ID# 204173 | Beijing, 100032, China Completed
The Second Hospital Central South University /ID# 204082 | Changsha, 410011, China Recruiting
Nanfang Hospital of Southern Medical University /ID# 204083 | Guangzhou, 510080, China Recruiting
Nanjing Drum Tower Hospital /ID# 204900 | Nanjing Jiangsu, 210008, China Recruiting
Duplicate_Tianjin Med Univ General Hosp /ID# 206994 | Tianjin, 300052, China Completed
Tongji Hospital Tongji Medical College Huazhong University of Science and Techno /ID# 204088 | Wuhan, 430030, China Completed
Hospital Pablo Tobon Uribe /ID# 202404 | Medellín, Antioquia, 50034, Colombia Recruiting
Hospital Universitario San Vic /ID# 200029 | Medellin, 50010, Colombia Recruiting
Poliklinika Solmed /ID# 211519 | Zagreb, Grad Zagreb, 10000, Croatia Recruiting
UHC Split /ID# 171191 | Split, 21000, Croatia Recruiting
Zadar General Hospital /ID# 205536 | Zadar, 23000, Croatia Completed
CH Dubrava /ID# 171185 | Zagreb, 10000, Croatia Recruiting
UHC Sestre Milosrdnice /ID# 205535 | Zagreb, 10000, Croatia Recruiting
UHC Zagreb /ID# 171203 | Zagreb, 10000, Croatia Recruiting
Nemocnice Ceske Budejovice a.s. /ID# 224389 | Ceske Budejovice, 370 01, Czechia Recruiting
Hepato-Gastroenterologie HK, s.r.o. /ID# 171401 | Hradec Kralove, 500 12, Czechia Recruiting
Artroscan s.r.o. /ID# 200790 | Ostrava, 722 00, Czechia Recruiting
ResTrial s.r.o. /ID# 208653 | Praha, 143 00, Czechia Recruiting
Nordsjallands Hospital /ID# 202424 | Frederikssund, Hovedstaden, 3600, Denmark Recruiting
Herlev Hospital /ID# 202423 | Herlev, Hovedstaden, 2730, Denmark Recruiting
Sjaellands Universitets Hospital /ID# 209445 | Roskilde, Sjælland, 4000, Denmark Completed
Hvidovre Hospital /ID# 202425 | Hvidovre, 2650, Denmark Recruiting
Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 171012 | Alexandria, 21131, Egypt Recruiting
Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 171013 | Alexandria, 21131, Egypt Recruiting
Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 209564 | Alexandria, 21131, Egypt Recruiting
National Hepatology and Tropical Medicine Research Institute /ID# 170989 | Cairo, 11559, Egypt Recruiting
Air Force Specialized Hospital /ID# 170996 | Cairo, Egypt Recruiting
National Liver Institute /ID# 170988 | Menoufiya, 35111, Egypt Recruiting
West Tallinn Central Hospital /ID# 202785 | Tallinn, 10617, Estonia Recruiting
CHU Grenoble Alpes - Hopital /ID# 219034 | Grenoble, 38043, France Recruiting
Clinique Jules Verne /ID# 219073 | Nantes, 44300, France Recruiting
CH Valenciennes /ID# 219035 | Valenciennes, 59300, France Recruiting
Universitatsklinikum Mannheim /ID# 168759 | Mannheim, Baden-Wuerttemberg, 68167, Germany Recruiting
Universitaetsklinikum Ulm /ID# 203560 | Ulm, Baden-Wuerttemberg, 89081, Germany Recruiting
Universitaetsklinikum Erlangen /ID# 203552 | Erlangen, Bayern, 91054, Germany Recruiting
Universitaetsklinikum Frankfurt /ID# 203566 | Frankfurt am Main, Hessen, 60590, Germany Recruiting
Zentrum für Gastroenterologie Saar MVZ GmbH /ID# 206741 | Saarbrücken, Saarland, 66111, Germany Recruiting
Universitaetsklinikum Schleswig-Holstein Campus Kiel /ID# 168757 | Kiel, Schleswig-Holstein, 24105, Germany Recruiting
Gastroenterologie am Mexikoplatz /ID# 203575 | Berlin, 14163, Germany Completed
Universitaetsmedizin Essen St. Josef Krankenhaus Werden /ID# 203570 | Essen, 45239, Germany Recruiting
Agaplesion Markus Krankenhaus /ID# 168758 | Frankfurt am Main, 60431, Germany Recruiting
Universitaetsklinikum Halle (Saale) /ID# 207455 | Halle (Saale), 06120, Germany Recruiting
Medizinisches Versorgungszentrum Portal 10 /ID# 200214 | Muenster, 48155, Germany Recruiting
General Hospital of Athens Ippokratio /ID# 167045 | Athens, Attiki, 11527, Greece Recruiting
General Hospital of Chest Diseases of Athens SOTIRIA /ID# 202104 | Athens, Attiki, 11527, Greece Recruiting
Tzaneio general hospital of Piraeus /ID# 206433 | Piraeus, Attiki, 18536, Greece Recruiting
University General Hospital of Heraklion PA.G.N.I /ID# 167044 | Heraklion, Kriti, 71307, Greece Recruiting
Genl Hosp Thess Ippokrateio /ID# 208825 | Thessaloniki, 54642, Greece Recruiting
Tuen Mun Hospital /ID# 171218 | Tuen Mun, 999077, Hong Kong Completed
Mohacsi Korhaz /ID# 209441 | Mohács, Baranya, 7700, Hungary Recruiting
CRU Hungary Egeszsegugyi és Szolgaltato Kft. /ID# 205547 | Miskolc, Borsod-Abauj-Zemplen, 3529, Hungary Recruiting
Bugat Pal Korhaz /ID# 201893 | Gyöngyös, Heves, 3200, Hungary Recruiting
Szent Borbala Korhaz /ID# 209897 | Tatabanya, Komarom-Esztergom, 2800, Hungary Recruiting
Obudai Egeszsegugyi Centrum Kft. /ID# 201892 | Budapest, Pest, 1036, Hungary Recruiting
MH Honvedkorhaz /ID# 201724 | Budapest, 1062, Hungary Recruiting
Semmelweis Egyetem /ID# 210167 | Budapest, 1085, Hungary Recruiting
Debreceni Egyetem Kenezy Gyula /ID# 201723 | Debrecen, 4031, Hungary Recruiting
Debreceni Egyetem Klinikai Kozpont /ID# 216419 | Debrecen, 4032, Hungary Recruiting
Pest Megyei Flor Ferenc Korhaz /ID# 206154 | Kistarcsa, 2143, Hungary Completed
Mentahaz Maganorvosi Kozpont /ID# 201895 | Szekesfehervar, 8000, Hungary Completed
Mercy University Hospital /ID# 206511 | Cork, T12 WE28, Ireland Completed
Soroka Medical Center /ID# 169913 | Be'er Sheva, HaDarom, 8443901, Israel Recruiting
Tel Aviv Sourasky Medical Center /ID# 204877 | Tel Aviv-Yafo, Tel-Aviv, 6423906, Israel Recruiting
Hadassah Medical Center-Hebrew University /ID# 169928 | Jerusalem, Yerushalayim, 91120, Israel Recruiting
Assaf Harofeh Medical Center /ID# 204872 | Be'Er Ya'Akov, 70300, Israel Recruiting
Rabin Medical Center /ID# 202636 | Petakh Tikva, 4941492, Israel Recruiting
Kaplan Medical Center /ID# 170276 | Rehovot, 7661041, Israel Recruiting
AOU Policlinico S. Orsola Malpighi /ID# 168187 | Bologna, Emilia-Romagna, 40138, Italy Recruiting
Policlinico Universitario Campus Bio-Medico /ID# 168183 | Rome, Lazio, 00128, Italy Recruiting
Azienda Ospedaliera San Camillo Forlanini /ID# 168184 | Rome, Lazio, 00152, Italy Recruiting
Istituto Clinico Humanitas /ID# 168185 | Rozzano, Milano, 20089, Italy Recruiting
Fondazione PTV Policlinico Tor Vergata /ID# 168188 | Rome, Roma, 00133, Italy Recruiting
Presidio Columbus-Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Un /ID# 168182 | Rome, Roma, 00168, Italy Recruiting
IRCCS Ospedale Sacro Cuore Don Calabria /ID# 168186 | Negrar, Verona, 37024, Italy Recruiting
A.O. Per L'Emergenza Cannizzaro /ID# 168190 | Catania, 95126, Italy Recruiting
Policlinico San Martino/Univer /ID# 168191 | Genova, 16132, Italy Recruiting
ASST Fatebenefratelli Sacco - Ospedale Fatebenefratelli e Oftalmico /ID# 168181 | Milano, 20121, Italy Recruiting
ASST Grande Ospedale Metropolitano Niguarda /ID# 170849 | Milano, 20162, Italy Recruiting
Azienda Ospedaliero-Universitaria di Modena /ID# 201897 | Modena, 41124, Italy Recruiting
Ospedali Riuniti Villa Sofia-C /ID# 168189 | Palermo, 90146, Italy Recruiting
AOU Pisana /ID# 202421 | Pisa, 56124, Italy Recruiting
Aichi Medical University Hospital /ID# 165971 | Nagakute-shi, Aichi, 480-1195, Japan Completed
Nagoya City University Hospital /ID# 165970 | Nagoya shi, Aichi, 467-8602, Japan Completed
Nagoya University Hospital /ID# 165969 | Nagoya-shi, Aichi, 453-8511, Japan Active, not recruiting
Toyohashi Municipal Hospital /ID# 200175 | Toyohashi-shi, Aichi, 441-8570, Japan Completed
Hirosaki National Hospital /ID# 165961 | Hirosaki-shi, Aomori, 036-8545, Japan Recruiting
Toho University Medical Center Sakura Hospital /ID# 165963 | Sakura-shi, Chiba, 285-8741, Japan Recruiting
Kurume University Hospital /ID# 166012 | Kurume-shi, Fukuoka, 830-0011, Japan Recruiting
National Hospital Organization Takasaki General Medical Center /ID# 167127 | Takasaki-shi, Gunma, 370-0829, Japan Completed
NHO Fukuyama Medical Center /ID# 167131 | Fukuyama-shi, Hiroshima, 720-8520, Japan Recruiting
Duplicate_Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital /ID# 166014 | Hiroshima-shi, Hiroshima, 730-8619, Japan Active, not recruiting
Asahikawa Medical University Hospital /ID# 167120 | Midorigaokahiga-shi, Hokkaido, 078-8510, Japan Recruiting
Sapporo IBD Clinic /ID# 223561 | Sapporo-shi, Hokkaido, 064-0919, Japan Active, not recruiting
Duplicate_Sapporo Higashi Tokushukai Hospital /ID# 165960 | Sapporo-shi, Hokkaido, 065-0033, Japan Active, not recruiting
Duplicate_Sapporo Higashi Tokushukai Hospital /ID# 167124 | Sapporo-shi, Hokkaido, 065-0033, Japan Active, not recruiting
Kobe Home Clinic of Neurology /ID# 166009 | Kobe-shi, Hyogo, 650-0015, Japan Recruiting
Hyogo College of Medicine College Hospital /Id# 165973 | Nishinomiya-shi, Hyogo, 663-8501, Japan Active, not recruiting
Kanazawa University Hospital /ID# 169218 | Kanazawa-shi, Ishikawa, 920-8641, Japan Recruiting
Sameshima Hospital /ID# 206675 | Kagoshima-shi, Kagoshima, 892-0846, Japan Recruiting
Shin-Yurigaoka General Hospital /ID# 206654 | Kawasaki City, Kanagawa, 2150026, Japan Recruiting
Shin-Yurigaoka General Hospital /ID# 227137 | Kawasaki City, Kanagawa, 2150026, Japan Recruiting
Yokohama City University Medical Center /ID# 167128 | Yokohama shi, Kanagawa, 232-0024, Japan Active, not recruiting
Japanese Red Cross Kyoto Daiichi Hosital /ID# 165972 | Kyoto-shi, Kyoto, 605-0981, Japan Recruiting
Duplicate_Duplicate_Duplicate_Kyoto University Hospital /ID# 169889 | Kyoto-shi, Kyoto, 606-8507, Japan Completed
Yokkaichi Hazu Medical Center /ID# 167196 | Yokkaichi-shi, Mie, 510-0016, Japan Recruiting
Tohoku Rosai Hospital /ID# 167122 | Sendai-shi, Miyagi, 981-8563, Japan Recruiting
Nara Medical University Hospital /ID# 169219 | Kashihara-shi, Nara, 634-8522, Japan Recruiting
Kenseikai Dongo Hospital /ID# 208104 | Yamatotakada-shi, Nara, 635-0022, Japan Recruiting
Niigata Cancer Center Hospital /ID# 170045 | Niigata-shi, Niigata, 951-8566, Japan Completed
Ishida Clinic of IBD and Gastroenterology /ID# 167121 | Oita-shi, Oita, 870-0823, Japan Recruiting
Chikuba Hospital for Proctological and Gastrointestinal Diseases /ID# 166010 | Kurashiki-shi, Okayama, 710-0142, Japan Active, not recruiting
Duplicate_Japanese Red Cross Okayama Hospital /ID# 167356 | Okayama-shi, Okayama, 700-8607, Japan Completed
National Hospital Organization Osaka Minami Medical Center /ID# 206326 | Kawachinagano Shi, Osaka, 586-8521, Japan Active, not recruiting
Shimizu-Clinic /ID# 218872 | Osaka-shi, Osaka, 533-0005, Japan Active, not recruiting
Osaka City University Hospital /ID# 166015 | Osaka-shi, Osaka, 545-8586, Japan Completed
Osaka University Hospital /ID# 169663 | Suita-shi, Osaka, 565-0871, Japan Active, not recruiting
Tokitokai Tokito clinic /ID# 165962 | Saitama-shi, Saitama, 336-0963, Japan Recruiting
Shiga University of Medical Science Hospital /ID# 167129 | Otsu-shi, Shiga, 520-2192, Japan Completed
Hamamatsu University Hospital /ID# 224352 | Hamamatsu-shi, Shizuoka, 431-3192, Japan Active, not recruiting
Shizuoka Medical Centre /ID# 167125 | Sunto-shi, Shizuoka, 411-8611, Japan Recruiting
Duplicate_Tokai University Hachioji Hospital /ID# 165967 | Hachioji-shi, Tokyo, 192-0032, Japan Recruiting
Kyorin University Hospital /ID# 165966 | Mitaka-shi, Tokyo, 181-8611, Japan Recruiting
Tokyo Medical University Hospital /ID# 165965 | Shinjuku-ku, Tokyo, 160-0023, Japan Completed
Tokyo Medical University Hospital /ID# 167130 | Shinjuku-ku, Tokyo, 160-0023, Japan Recruiting
Tokyo Medical University Hospital /ID# 205980 | Shinjuku-ku, Tokyo, 160-0023, Japan Recruiting
Toyama Prefectural Central Hospital /ID# 217834 | Toyama-shi, Toyama, 930-8550, Japan Active, not recruiting
Japanese Red Cross Wakayama Medical Center /ID# 200643 | Wakayama-shi, Wakayama, 640-8558, Japan Recruiting
Wakayama Medical University Hospital /ID# 169482 | Wakayama-shi, Wakayama, 641-8510, Japan Recruiting
Yamagata University Hospital /ID# 200157 | Yamagata-shi, Yamagata, 990-9585, Japan Recruiting
Shunan Memorial Hospital /ID# 214404 | Kudamatsu-shi, Yamaguchi, 744-0033, Japan Recruiting
Yamanashi Prefectural Central Hospital /ID# 202464 | Kofu-shi, Yamanashi, 400-8506, Japan Completed
Hanyang University Guri Hospital /ID# 167587 | Guri, Gyeonggido, 11923, Korea, Republic of Completed
CHA Bundang Medical center CHA University /ID# 167592 | Seongnam si, Gyeonggido, 13496, Korea, Republic of Completed
Kangbuk Samsung Hospital /ID# 167586 | Seoul, Seoul Teugbyeolsi, 03181, Korea, Republic of Recruiting
Yonsei University Health System Severance Hospital /ID# 167590 | Seoul, Seoul Teugbyeolsi, 03722, Korea, Republic of Completed
Inje University Haeundae Hospital /ID# 202630 | Busan, 48108, Korea, Republic of Recruiting
Dong-A University Hospital /ID# 167591 | Busan, 49201, Korea, Republic of Recruiting
Pusan National University Hospital /ID# 167589 | Busan, 49241, Korea, Republic of Completed
Kyungpook National Univ Hosp /ID# 207019 | Daegu, 41944, Korea, Republic of Recruiting
Samsung Medical Center /ID# 167588 | Seoul, 06351, Korea, Republic of Recruiting
Chung-Ang University Hostipal /ID# 207018 | Seoul, 06973, Korea, Republic of Recruiting
Riga East Clinical Univ Hosp /ID# 169498 | Riga, 1038, Latvia Recruiting
P. Stradins Clinical Univ Hosp /ID# 169519 | Riga, LV-1002, Latvia Recruiting
Digestive Diseases Ctr Gastro /ID# 169508 | Riga, LV-1006, Latvia Recruiting
Duplicate_LUHS hospital Kauno Klinikos /ID# 206936 | Kovno, 50161, Lithuania Recruiting
Vilnius University Hospital /ID# 203286 | Vilnius, LT-08661, Lithuania Recruiting
Hospital Sultanah Bahiyah /ID# 202626 | Alor Setar, Kedah, 05460, Malaysia Recruiting
Universiti Kebangsaan Malaysia (UKM) Medical Centre /ID# 170773 | Kuala Lumpur, Selangor, 56000, Malaysia Recruiting
Universiti Sains Malaysia /ID# 200102 | Kelantan, 16150, Malaysia Recruiting
Instituto de Investigaciones Aplicadas a la Neurociencias A.C. /ID# 207579 | Victoria de Durango, Durango, 34000, Mexico Recruiting
Morales Vargas Centro de Investigacion S.C. /ID# 203494 | Leon, Guanajuato, 37000, Mexico Recruiting
Clinica de Investigacion en Reumatologia y Obesidad S.C. /ID# 207238 | Guadalajara, Jalisco, 44650, Mexico Recruiting
Radboud Universitair Medisch Centrum /ID# 166928 | Nijmegen, Gelderland, 6525 GA, Netherlands Recruiting
Zuyderland Medisch Centrum /ID# 169700 | Heerlen, Limburg, 6419 PC, Netherlands Recruiting
Onze Lieve Vrouwe Gasthuis /ID# 166929 | Amsterdam, 1091 AC, Netherlands Recruiting
Academisch Medisch Centrum /ID# 166927 | Amsterdam, 1105 AZ, Netherlands Recruiting
Medisch Spectrum Twente /ID# 170298 | Enschede, 7512 KZ, Netherlands Completed
Vistamed /ID# 208572 | Wroclaw, Dolnoslaskie, 53-149, Poland Completed
Malopolskie Centrum Kliniczne /ID# 202167 | Krakow, Malopolskie, 30-149, Poland Recruiting
WIP Warsaw IBD Point Profesor Kierkus /ID# 224301 | Warsaw, Mazowieckie, 00-728, Poland Recruiting
Centrum Medyczne Reuma Park w Warszawie /ID# 200490 | Warsaw, Mazowieckie, 02-691, Poland Recruiting
Centrum Zdrowia MDM /ID# 200491 | Warszawa, Mazowieckie, 00-635, Poland Recruiting
Hospital da Senhora da Oliveira Guimaraes, EPE /ID# 170245 | Guimaraes, Braga, 4835-044, Portugal Recruiting
Hospital Egas Moniz /ID# 170253 | Lisbon, Porto, 1349-019, Portugal Recruiting
Unidade Local de Saúde do Alto Minho, EPE - Hospital Conde de Bertiandos /ID# 200607 | Ponte de Lima, Viana Do Castelo, 4990-041, Portugal Recruiting
Hospital Garcia de Orta, EPE /ID# 170241 | Almada, 2805-267, Portugal Recruiting
Centro Hospitalar Universitario de Sao Joao, EPE /ID# 170248 | Porto, 4200-319, Portugal Recruiting
Mindful Medical Research /ID# 203358 | San Juan, 00918-3756, Puerto Rico Recruiting
School of Medicine University of Puerto Rico-Medical Science Campus /ID# 166771 | San Juan, 00935, Puerto Rico Recruiting
Institutul Clinic Fundeni /ID# 167817 | Sector 2, Bucuresti, 022328, Romania Recruiting
Clinica GASTRO MED SRL /ID# 206369 | Cluj-Napoca, Cluj, 400380, Romania Recruiting
Cabinet Particular Policlinic Algomed /ID# 167818 | Timisoara, 300002, Romania Recruiting
Immanuel Kant Baltic Federal University /ID# 203811 | Kaliningrad, Kaliningradskaya Oblast, 236016, Russian Federation Recruiting
Perm Clinical Center of the Federal Medical and Biological Agency /ID# 202990 | Perm, Permskiy Kray, 614109, Russian Federation Recruiting
LLC Novaya Klinika /ID# 206616 | Pyatigorsk, Stavropol Skiy Kray, 357500, Russian Federation Recruiting
Professor Pasechnikov Gastroenterology and Pankreatology clinic /ID# 202997 | Stavropol, Stavropol Skiy Kray, 355012, Russian Federation Completed
Kazan State Medical University /ID# 169638 | Kazan, Tatarstan, Respublika, 420012, Russian Federation Recruiting
Olla-Med Clinic /ID# 208720 | Moscow, 105554, Russian Federation Recruiting
P.A. Bayandin Murmansk Regiona /ID# 169639 | Murmansk, 183047, Russian Federation Recruiting
Medical Center Zdorovaya Semya /ID# 209236 | Novosibirsk, 630099, Russian Federation Recruiting
Republican hospital named after V.A. Baranov /ID# 206488 | Petrozavodsk, 185019, Russian Federation Recruiting
Euromedservice /ID# 206610 | Pushkin, 196603, Russian Federation Recruiting
X7 Clinical Research Center /ID# 216350 | Saint Petersburg, 194156, Russian Federation Recruiting
City Clinical Hospital No. 31 /ID# 208868 | St. Petersburg, 197110, Russian Federation Recruiting
Clinical Hosp Center Zvezdara /ID# 168214 | Belgrade, Beograd, 11000, Serbia Recruiting
Military Medical Academy /ID# 168783 | Belgrade, Beograd, 11000, Serbia Recruiting
University Clinical Center Serbia /ID# 168215 | Belgrade, Beograd, 11000, Serbia Recruiting
Clin Hosp Ctr Bezanijska Kosa /ID# 168750 | Belgrade, Beograd, 11080, Serbia Recruiting
University Clinical Center Kragujevac /ID# 205859 | Kragujevac, Sumadijski Okrug, 34000, Serbia Recruiting
Clinical Center Vojvodina /ID# 168213 | Novi Sad, Vojvodina, 21000, Serbia Recruiting
KL Ling Gastroenterology and Liver Clinic /ID# 217962 | Singapore, 228510, Singapore Recruiting
Gleneagles Medical Centre /ID# 206531 | Singapore, 258499, Singapore Recruiting
Tan Tock Seng Hospital /ID# 203160 | Singapore, 308433, Singapore Recruiting
FNsP F.D.Roosevelta Banska Bystrica /ID# 169958 | Banska Bystrica, Banskobystricky Kraj, 975 17, Slovakia Recruiting
KM Management s.r.o. /ID# 170201 | Nitra, 949 01, Slovakia Recruiting
Univ Medical Ctr Ljubljana /ID# 217795 | Ljubljana, 1000, Slovenia Recruiting
Farmovs (Pty) Ltd /Id# 207535 | Bloemfontein, Free State, 9301, South Africa Active, not recruiting
Lenasia Clinical Trial Centre /ID# 205145 | Johannesburg, Gauteng, 1820, South Africa Active, not recruiting
Wits Clinical Research Site /ID# 170852 | Johannesburg, Gauteng, 2193, South Africa Completed
Allergy & Immunology (AIU) /ID# 171431 | Cape Town, Western Cape, 7700, South Africa Completed
Dr JP Wright /ID# 170887 | Cape Town, Western Cape, 7708, South Africa Active, not recruiting
Private Practice Dr MN Rajabally /ID# 169853 | Cape Town, Western Cape, 7800, South Africa Active, not recruiting
Hospital Universitari Son Espases /ID# 201998 | Palma de Mallorca, Illes Balears, 07120, Spain Completed
Complejo Hospitalario de Navarra /ID# 202355 | Pamplona, Navarra, 31008, Spain Recruiting
Hospital Universitario A Coruna - CHUAC /ID# 203910 | A Coruna, 15006, Spain Recruiting
Hospital Clinic de Barcelona /ID# 201990 | Barcelona, 08036, Spain Recruiting
Hospital Universitario de Girona Doctor Josep Trueta /ID# 202645 | Girona, 17007, Spain Recruiting
Hospital Juan Ramon Jimenez /ID# 201995 | Huelva, 21005, Spain Completed
Hospital Universitario La Paz /ID# 201994 | Madrid, 28046, Spain Recruiting
Hospital Clinico Universitario de Salamanca /ID# 206358 | Salamanca, 37007, Spain Completed
Hospital Universitario Virgen Macarena /ID# 201993 | Sevilla, 41009, Spain Recruiting
Hospital Clinico Universitario de Valencia /ID# 209657 | Valencia, 46010, Spain Recruiting
Hospital Universitario y Politecnico La Fe /ID# 201992 | Valencia, 46026, Spain Recruiting
Karolinska University Hospital Solna /ID# 224488 | Solna, Stockholms Lan, 171 64, Sweden Recruiting
Alingsås lasarett /ID# 170826 | Alingsås, Vastra Gotalands Lan, 441 33, Sweden Recruiting
Sodra Alvsborgs sjukhus /ID# 203077 | Boras, Vastra Gotalands Lan, 501 82, Sweden Recruiting
Sahlgrenska US Gbg /ID# 169171 | Göteborg, Vastra Gotalands Lan, 413 46, Sweden Recruiting
Hallands sjukhus Halmstad /ID# 170828 | Halmstad, 302 33, Sweden Recruiting
Inselspital, Universitätsspital Bern /ID# 170997 | Bern, 3010, Switzerland Recruiting
Universitatsspital Zurich /ID# 170998 | Zurich, CH-8091, Switzerland Recruiting
China Medical University Hosp /ID# 169791 | Taichung City, Taichung, 40447, Taiwan Recruiting
Taichung Veterans General Hosp /ID# 169790 | Taichung City, 40705, Taiwan Recruiting
National Taiwan University Hospital /ID# 169792 | Taipei City, 10002, Taiwan Recruiting
Acibadem Kozyatagi Hospital /ID# 209406 | Kadikoy, Istanbul, 34742, Turkey Recruiting
Erciyes University Medical Fac /ID# 171331 | Melikgazi, Kayseri, 38030, Turkey Completed
Ankara Univ Medical Faculty /ID# 206409 | Ankara, 06590, Turkey Recruiting
Inonu Universitesi Turgut Ozal /ID# 201268 | Battalgazi/malatya, 44280, Turkey Completed
Mustafa Kemal University Medic /ID# 171336 | Hatay, 31001, Turkey Completed
Istanbul University Istanbul Medical Faculty /ID# 171364 | Istanbul, 34093, Turkey Recruiting
Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi /ID# 171332 | Istanbul, 34899, Turkey Recruiting
Mersin University Medical /ID# 171338 | Mersin, 33343, Turkey Recruiting
Sisli Etfal Train & Res Hosp /ID# 171334 | Sisli, 34371, Turkey Completed
Gazi Universitesi Tip Fakultes /ID# 217444 | Yenimahalle, 06560, Turkey Recruiting
Medical Centre of "Ukrainian German Antiulcer Gastroenterology Centre BYK-KYIV" /ID# 203738 | Kyiv, Kyivska Oblast, 01030, Ukraine Recruiting
Kharkiv City Clinical Hospital No.2 n.a. Prof. O.O. Shalimov /ID# 167907 | Kharkiv, 61037, Ukraine Recruiting
MNE Kyiv City Clinical Hospital no.18 /ID# 207889 | Kyiv, 01030, Ukraine Recruiting
MI of Kyiv Regional Rada Kyiv Regional Clinical Hospital /ID# 202454 | Kyiv, 04107, Ukraine Recruiting
Lviv Railway Clinical Hospital of branch Healthcare Centers of Public Joint Stoc /ID# 167908 | Lviv, 79000, Ukraine Recruiting
MNPE Vinnytsia Regional Clinical Hospital n.a. M.I. Pyrohov /ID# 222110 | Vinnytsia, 21018, Ukraine Recruiting
South Eastern Health and Social Care Trust /ID# 205323 | Belfast, Antrim, BT16 1RH, United Kingdom Recruiting
Warrington and Halton Hospitals NHS Foundation Trust /ID# 171383 | Warrington, Cheshire West And Chester, WA5 1QG, United Kingdom Recruiting
Royal United Hospitals Bath /ID# 169074 | Bath, BA1 3NG, United Kingdom Recruiting
Queen Elizabeth Hospital - BIRMINGHAM /ID# 169070 | Birmingham, B15 2TH, United Kingdom Recruiting
The Dudley Group NHS /ID# 169069 | Dudley, DY1 2HQ, United Kingdom Recruiting
King's College Hospital NHS Foundation Trust /ID# 169072 | London, SE5 9RS, United Kingdom Recruiting
The Newcastle Upon Tyne Hospitals NHS Foundation Trust /ID# 169075 | Newcastle Upon Tyne, NE1 4LP, United Kingdom Recruiting
St. Helens and Knowsley Teach /ID# 209086 | Prescot, L35 5DR, United Kingdom Recruiting
Stockport NHS foundation trust /ID# 208719 | Stockport, SK2 7JE, United Kingdom Recruiting
Taunton and Somerset NHS Found /ID# 209665 | Tauntojn, TA1 5DN, United Kingdom Recruiting
St Georges NHS Foundation Hospital /ID# 205552 | Tooting, SW17 0QT, United Kingdom Recruiting
New Cross Hospital, Royal Wolv /ID# 171382 | Wolverhampton, WV10 0QP, United Kingdom Active, not recruiting
Standort Länder

Argentina

Australia

Austria

Belgium

Bosnia and Herzegovina

Brazil

Bulgaria

Canada

Chile

China

Colombia

Croatia

Czechia

Denmark

Egypt

Estonia

France

Germany

Greece

Hong Kong

Hungary

Ireland

Israel

Italy

Japan

Korea, Republic of

Latvia

Lithuania

Malaysia

Mexico

Netherlands

Poland

Portugal

Puerto Rico

Romania

Russian Federation

Serbia

Singapore

Slovakia

Slovenia

South Africa

Spain

Sweden

Switzerland

Taiwan

Turkey

Ukraine

United Kingdom

United States

Überprüfungsdatum

2021-07-01

Verantwortliche Partei

Art: Sponsor

Schlüsselwörter
Hat den Zugriff erweitert Nein
Anzahl der Waffen 2
Armgruppe

Etikette: Arm A: Upadacitinib

Art: Experimental

Beschreibung: Participants will receive Upadacitinib dose A for 12 weeks. Non-responders will receive Upadacitinib dose B for 12 weeks

Etikette: Arm B: Placebo und Upadacitinib

Art: Experimental

Beschreibung: Die Teilnehmer erhalten 12 Wochen lang Placebo. Non-Responder erhalten 12 Wochen lang Upadacitinib-Dosis A.

Studiendesign Info

Zuweisung: Zufällig

Interventionsmodell: Parallele Zuweisung

Hauptzweck: Behandlung

Maskierung: Vierfach (Teilnehmer, Leistungserbringer, Prüfarzt, Ergebnisbewerter)

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact [email protected]. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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