Forced-Air Warming for Preventing Perioperative Hypothermia During Total Knee Arthroplasty
Effect of Intraoperative Forced-air Warming on Perioperative Hypothermia and Related Complications in Patients Undergoing Total Knee Arthroplasty: A Historical Control Study
Perioperative hypothermia is a common complication during total knee arthroplasty (TKA) and may increase the risk of shivering, delayed anesthetic recovery, and postoperative complications. This historical control study aims to evaluate the effectiveness and safety of intraoperative forced-air warming in preventing perioperative hypothermia in patients undergoing primary unilateral TKA.
A total of 240 patients were included. Patients in the historical control group received routine passive warming measures, while patients in the intervention group received additional forced-air warming during the perioperative period. Core body temperature, incidence of inadvertent perioperative hypothermia, anesthetic recovery outcomes, postoperative complications, and safety outcomes were evaluated.
Descripción general del estudio
Estado
Intervención / Tratamiento
Descripción detallada
This single-center historical control study was conducted at Shanghai 6th People's Hospital between May 2018 and December 2018 to evaluate the effectiveness of intraoperative forced-air warming for preventing perioperative hypothermia in patients undergoing total knee arthroplasty (TKA).
A total of 240 patients undergoing primary unilateral TKA were enrolled and divided into two groups according to the study period. Patients enrolled between May 2018 and August 2018 were assigned to the historical control group and received routine passive warming measures, including warmed intravenous fluids, warmed irrigation fluids, operating room temperature control, and cotton blanket coverage. Patients enrolled between September 2018 and December 2018 were assigned to the intervention group and received additional active warming using a forced-air warming system during the perioperative period.
The forced-air warming system was initiated 30 minutes before anesthesia induction and continued until transfer to the post-anesthesia care unit (PACU). Core temperature was continuously monitored using a temperature-sensing urinary catheter.
The primary outcomes included perioperative core temperature changes and the incidence of inadvertent perioperative hypothermia, defined as core temperature below 36°C at any perioperative time point. Secondary outcomes included postoperative shivering, emergence agitation, anesthetic recovery time, blood loss, postoperative complications, and safety outcomes including skin burns and surgical site infection.
This study was approved by the Ethics Committee of Shanghai 6th People's Hospital (Approval No. 05.12.19035). Written informed consent was obtained from all participants before enrollment.
Tipo de estudio
Inscripción (Actual)
Fase
- No aplica
Contactos y Ubicaciones
Ubicaciones de estudio
-
-
Shanghai Municipality
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Shanghai, Shanghai Municipality, Porcelana, 200233
- Shanghai 6th People's Hospital
-
-
Criterios de participación
Criterio de elegibilidad
Edades elegibles para estudiar
- Adulto
- Adulto Mayor
Acepta Voluntarios Saludables
Descripción
Inclusion Criteria:
- Age between 60 and 85 years
- ASA physical status I or II
- Diagnosed with knee osteoarthritis
- Undergoing first unilateral primary total knee arthroplasty
- Able to provide written informed consent
Exclusion Criteria:
- Abnormal coagulation function (international normalized ratio >1.2)
- Preoperative body temperature >37.5°C or <36°C
- Cognitive or psychiatric disorders affecting communication
- Moderate or severe anemia
- Body mass index >30 kg/m² or <18.5 kg/m²
- Moderate or severe malnutrition
- Surgery duration longer than 4 hours
- Intraoperative blood loss greater than 500 mL
- Transfer to surgical intensive care unit after surgery
Plan de estudios
¿Cómo está diseñado el estudio?
Detalles de diseño
- Propósito principal: Prevención
- Asignación: No aleatorizado
- Modelo Intervencionista: Asignación paralela
- Enmascaramiento: Ninguno (etiqueta abierta)
Armas e Intervenciones
Grupo de participantes/brazo |
Intervención / Tratamiento |
|---|---|
|
Experimental: Forced-Air Warming Group
Participants received routine passive warming measures plus active warming using a forced-air warming system during the perioperative period.
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Active perioperative warming using a forced-air warming system initiated 30 minutes before anesthesia induction and continued until transfer to the post-anesthesia care unit.
|
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Comparador activo: Routine Warming Group
Participants received routine passive warming measures including warmed fluids, operating room temperature control, and cotton blanket coverage.
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Routine perioperative warming measures including warmed intravenous fluids, warmed irrigation fluids, operating room temperature control, and cotton blanket coverage.
|
¿Qué mide el estudio?
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
|
Incidence of Inadvertent Perioperative Hypothermia
Periodo de tiempo: From anesthesia induction to 90 minutes after anesthesia completion
|
The proportion of participants with core body temperature below 36.0°C at any perioperative time point.
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From anesthesia induction to 90 minutes after anesthesia completion
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Perioperative Core Temperature Change
Periodo de tiempo: From operating room entry to 90 minutes after anesthesia completion
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Core body temperature measured using a temperature-sensing urinary catheter at predefined perioperative time points.
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From operating room entry to 90 minutes after anesthesia completion
|
Medidas de resultado secundarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
|
Postoperative Shivering
Periodo de tiempo: From the end of surgery to 24 hours postoperatively
|
Incidence and severity of postoperative shivering assessed using a 0-4 shivering scale.
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From the end of surgery to 24 hours postoperatively
|
|
Emergence Agitation
Periodo de tiempo: From 30 minutes after surgery to 2 hours postoperatively
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Incidence and severity of emergence agitation assessed using the Richmond Agitation-Sedation Scale (RASS, -5 to +4), where higher positive scores indicate greater agitation.
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From 30 minutes after surgery to 2 hours postoperatively
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|
Anesthetic Recovery Time
Periodo de tiempo: From the end of anesthesia to 2 hours postoperatively
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Recovery outcomes including awakening time, extubation time, and PACU length of stay.
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From the end of anesthesia to 2 hours postoperatively
|
|
Intraoperative Blood Loss
Periodo de tiempo: During surgery
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Estimated blood loss recorded during the surgical procedure.
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During surgery
|
|
Postoperative Complications
Periodo de tiempo: From the end of surgery to 30 days postoperatively
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Incidence of postoperative complications including delirium, nausea and vomiting, cardiac adverse events, skin burns, and surgical site infection.
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From the end of surgery to 30 days postoperatively
|
Colaboradores e Investigadores
Patrocinador
Investigadores
- Investigador principal: Danling Fang, RN, Shanghai 6th People's Hospital
Fechas de registro del estudio
Fechas importantes del estudio
Inicio del estudio (Actual)
Finalización primaria (Actual)
Finalización del estudio (Actual)
Fechas de registro del estudio
Enviado por primera vez
Primero enviado que cumplió con los criterios de control de calidad
Publicado por primera vez (Actual)
Actualizaciones de registros de estudio
Última actualización publicada (Actual)
Última actualización enviada que cumplió con los criterios de control de calidad
Última verificación
Más información
Términos relacionados con este estudio
Palabras clave
Otros números de identificación del estudio
- TKA-FAW-2018-01
Plan de datos de participantes individuales (IPD)
¿Planea compartir datos de participantes individuales (IPD)?
Descripción del plan IPD
Información sobre medicamentos y dispositivos, documentos del estudio
Estudia un producto farmacéutico regulado por la FDA de EE. UU.
Estudia un producto de dispositivo regulado por la FDA de EE. UU.
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