High Septal Pacing for Cardiac Resynchronization Therapy (HISTORY)

Inclusion Criteria:

• 50 years of age or older
• Patients willing and capable of providing informed consent, participating in all testing associated with this clinical investigation

• Patients undergoing a CRT implant procedure (pacemaker or defibrillator) for one of the following reasons

  • Indicated for a new device
  • Device upgrade
  • Device replacement
  • Lead revision
• Note: recognized indications for CRT-P and CRT-D as of October 2009 are valid for inclusion in this study. Should new indications become approved during the study conduct; those will also be applied within the inclusion criteria.

Exclusion Criteria:

• Patients unwilling or incapable of signing the informed consent, or patients having previously withdrawn their consent
• Patients in AF that cannot be cardioverted for the study
• RBBB pattern
• Sustained, uncontrolled ventricular tachycardia
• Sinus rhythm < 30 bpm or >100 bpm
• Complete AV node block
• Second degree AV block
• Women who are pregnant or plan to become pregnant during the study (method of assessment upon physician's discretion);
• History of (hemorrhagic) cerebro-vascular accident or TIA