- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02489682
Clinical Informed Consent Format Evaluation
Study Overview
Status
Conditions
Detailed Description
Traditional informed consent documents tend to be lengthy and technical, often too dense to facilitate proper patient-engagement. In this study, the investigators test the effectiveness of a previously developed patient-centered, short informed consent document and a patient-centered, short informed animated consent video as compared to a lengthy traditional informed consent document for the same clinical condition (i.e. severe asthma)
In this study, self-identified asthma patients, aged 18 or older, attending an experimental session in a university computer laboratory will be randomly assigned to read either the full informed consent document (control) or the short, patient-centered informed consent document or to view the short patient-centered informed consent video. Participants will also complete a follow-up survey at 1-week.
The main outcome measures are:
Engagement in the information (1=not at all engaged, 2=not very engaged, 3= somewhat engaged, 4=very engaged, 5=completely engaged).
Intention to enroll in the clinical trial
(1=definitely would not, 3=neutral, and 5=definitely would)
Trial knowledge (12 multiple choice questions, e.g. ""When can [the participants] withdraw from the trial?")
Trust in the clinical trial physician (Six questions beginning with, "If [the participant] decided to enroll in this study, how much would [the participant] trust Dr. Janet Taylor, the physician who is leading the study, to...")
Perceived risks and benefits of the trial (Four questions, e.g. "Imagine that [the participant] enrolled in the clinical trial, how likely do [the participants] think it is that the drug would be more effective in treating [the participant's] asthma symptoms than an average asthma drug on the market?")
The investigators hypothesize that the two experimental conditions will outperform the control condition on engagement and trial knowledge and would do as well as the control on the remaining outcome measures.
Study Type
Enrollment (Actual)
Phase
- Not Applicable
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Description
Inclusion Criteria:
- at least 18 years of age
- fluent in English
- self-identifying as asthma patients
Exclusion Criteria:
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Other
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Double
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Informed Consent Format - short written
Intervention to be administered: - Short-form written informed consent information, followed immediately by outcomes questionnaire |
|
Experimental: Informed Consent Format - long written
Intervention to be administered: - Long-form written informed consent information, followed immediately by outcomes questionnaire |
|
Experimental: Informed Consent Format - video
Intervention to be administered: - Video informed consent information, followed immediately by outcomes questionnaire |
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Hypothetical trial enrollment as assessed by a likelihood of enrollment question
Time Frame: immediately after intervention
|
immediately after intervention
|
Engagement as assessed by a likert scale engagement question
Time Frame: immediately after intervention
|
immediately after intervention
|
Trust in physician as assessed by a composite of likert scale questions measuring trust
Time Frame: immediately after intervention
|
immediately after intervention
|
Trial Knowledge as assessed by a composite of 12 true/false questions
Time Frame: immediately after intervention
|
immediately after intervention
|
Perceived Risk and Benefit as assessed by a series of judgment questions
Time Frame: immediately after intervention
|
immediately after intervention
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Change in hypothetical trial enrollment as assessed by a likelihood of enrollment question at 1 week from intervention
Time Frame: 1-week follow-up
|
1-week follow-up
|
Change in trust in physician as assessed by a composite of likert scale questions measuring trust at 1 week from intervention
Time Frame: 1-week follow-up
|
1-week follow-up
|
Change in hypothetical trial trial knowledge as assessed by a composite of 12 true/false questions at 1 week from intervention
Time Frame: 1-week follow-up
|
1-week follow-up
|
Change in Perceived Risk and Benefit as assessed by a series of judgment questions at 1 week from intervention
Time Frame: 1-week follow-up
|
1-week follow-up
|
Collaborators and Investigators
Sponsor
Collaborators
Study record dates
Study Major Dates
Study Start
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimated)
Study Record Updates
Last Update Posted (Estimated)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Other Study ID Numbers
- A016520
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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