Astringency and Bitterness Perception

August 27, 2018 updated by: Cordelia Running, PhD, Purdue University

Astringency and Bitterness Perception Among High and Low Fruit and Vegetable Consumers

The investigators are conducting a study to better understand how the average consumer differentiates between bitter and astringent sensations, both of which are typically unpleasant sensations characteristic of some healthy foods. Astringency is the dry/rough sensation elicited by foods such as green bananas and some wines. Although trained scientists can differentiate between these stimuli, untrained participants rate them similarly, despite their differences. This confusion has created additional barriers in understanding the mechanism of astringent perception, which is currently debated. Understanding how to design experiments where untrained participants can clearly evaluate both sensations will lay the foundation to better understand astringency.

One mechanism that is believed to contribute to astringency is the interaction of astringent stimuli with salivary proteins. Interestingly, the salivary protein profile may be influenced by consumption of fruits and vegetables. Therefore, the investigators will evaluate how bitter and astringent perceptions differ among high and low consumers of fruits and vegetables by collecting saliva following exposure to the stimuli. This knowledge will inform approaches to increase the appeal of healthy food.

Study Overview

Status

Completed

Conditions

Study Type

Observational

Enrollment (Actual)

92

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

    • Indiana
      • West Lafayette, Indiana, United States, 47907
        • Purdue University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 45 years (ADULT)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

  • Not underweight (BMI > 18 kg/m^2)
  • Not be trying to gain or lose weight
  • Males and females 18-45
  • No known issues with taste, smell, swallowing, choking, or salivation

Description

Inclusion Criteria:

  • BMI > 18

Exclusion Criteria:

  • issues with taste, smell, swallowing, choking, or salivation
  • trying to gain or lose weight

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Low fruit and vegetable consumers
Participants with low F&V consumption, as defined by 24-hr dietary recall
Participants will be involved in 1-4 experiments that test how they rate and differentiate between bitter and astringent flavored beverage samples
High fruit and vegetable consumers
Participants with high F&V consumption, as defined by 24-hr dietary recall
Participants will be involved in 1-4 experiments that test how they rate and differentiate between bitter and astringent flavored beverage samples

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Participant-generated sensory ratings of consumed samples
Time Frame: Through study completion, an average of three 30-minute visits
Liking and flavor intensity ratings on the general labeled magnitude scale
Through study completion, an average of three 30-minute visits
Participant-generated groupings of consumed samples
Time Frame: Through study completion, an average of three 60-minute visits
Hierarchical clustering of sample similarity
Through study completion, an average of three 60-minute visits
Participant-generated ratings of consumed samples relative to reference samples
Time Frame: Through study completion, an average of three 60-minute visits
Similarity ratings of samples compared to three reference samples on a visual analog scale
Through study completion, an average of three 60-minute visits
Participant-generated "check-all-that-apply" ratings of consumed samples
Time Frame: Through study completion, an average of three 30-minute visits
10-20 descriptors that are checked or unchecked by each participant to describe each sample
Through study completion, an average of three 30-minute visits

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (ACTUAL)

April 30, 2017

Primary Completion (ACTUAL)

May 30, 2018

Study Completion (ACTUAL)

May 30, 2018

Study Registration Dates

First Submitted

May 24, 2017

First Submitted That Met QC Criteria

May 25, 2017

First Posted (ACTUAL)

May 31, 2017

Study Record Updates

Last Update Posted (ACTUAL)

August 28, 2018

Last Update Submitted That Met QC Criteria

August 27, 2018

Last Verified

August 1, 2018

More Information

Terms related to this study

Other Study ID Numbers

  • 082-007

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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