Denne side blev automatisk oversat, og nøjagtigheden af oversættelsen er ikke garanteret. Der henvises til engelsk version for en kildetekst.

S0424 - Carcinogens in Lung Tissue From Smokers (Closed to Entry as of 7/15/07) and Non-Smokers With Newly Diagnosed Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer

23. oktober 2015 opdateret af: Southwest Oncology Group

Molecular Epidemiology Case-Series Study of Non-Small Cell Lung Cancer in Smoking and Non-Smoking Women and Men

RATIONALE: Studying samples of blood and tissue from smokers (closed to entry as of 7/15/07) and non-smokers with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors learn more about risk factors for lung cancer and may help the study of cancer in the future.

PURPOSE: This clinical trial is studying carcinogens in lung tissue from smokers (closed to entry as of 7/15/07) and non-smokers with newly diagnosed stage I, stage II, or stage III non-small cell lung cancer.

Studieoversigt

Status

Afsluttet

Betingelser

Lungekræft

Intervention / Behandling

Detaljeret beskrivelse

OBJECTIVES:

Assess lung tissue from patients with stage I, stage II, stage IIIA, or stage IIIB non-small cell lung cancer for specific tobacco smoke carcinogens (including polycyclic aromatic hydrocarbons [PAH] and DNA adducts, alterations in specific genes, including p53 and K-ras, and expression of HER2 and estrogen receptors α and β).
Determine whether tobacco smoke carcinogens differ by gender and smoking status, adjusting for potential exposures and influential factors, including family smoking status, medication use, and hormonal and reproductive factors.
Measure the levels of PAH-DNA adducts in lymphocytes and lung tissue and examine correlations between the two tissue sources.
Determine whether DNA damage levels in tissue as well as in lymphocytes are higher in females than in males for the same level of smoking.
Determine polymorphisms in several genes involved in the metabolism of the specific carcinogens investigated and in steroidogenesis and metabolism.
Summarize patient self-report questionnaire data on active and passive smoking, other carcinogenic exposures, smoking preference, economic and educational status, family smoking status, reproductive factors, weight loss, and medication use by categories of male versus female and never-smoker versus ever-smoker.

OUTLINE: This is a case-series, multicenter study. Patients are stratified according to gender and smoking status (never smoker [< 100 cigarettes smoked during lifetime] vs ever smoker [≥ 100 cigarettes smoked during lifetime] [closed to accrual as of 7/15/07]).

Patients complete the Lung Cancer Epidemiology Questionnaire for detailed assessment of the following:

Exposure to active and passive smoke
Occupational exposures
Reproductive and hormonal risk factors
Weight loss
Economic and educational status
Family smoking status
Medication use
Other variables relevant for the analysis (e.g., HER2, estrogen receptor status) Peripheral blood samples are collected for research studies. Previously collected tissue samples are also studied in the laboratory. Samples are examined for DNA adduct levels. Estrogen receptor α and β are assessed by immunohistochemistry (IHC). HER2 expression and amplification are measured by chromogenic in situ hybridization. IHC and DNA-polymerase chain reaction (PCR)-single-stranded conformational polymorphism assay are used to analyze p53 mutations. RAS mutations are analyzed with restriction fragment length polymorphism-PCR assay. Polycyclic aromatic hydrocarbons and 4-aminobiphenyl-DNA damage are assessed by IHC and immunofluorescence. Matrix-assisted laser desorption/ionization time of flight mass spectrometry is used to genotype polymorphisms, including CYP1A1, CYP1B1, GSTM1, GSTP1, MPO, NAT-1, NAT-2, CYP19, CYP17, SULT1A1.

Patients are followed annually for up to 5 years.

PROJECTED ACCRUAL: A total of 900 patients will be accrued for this study (female and male smoker strata closed to accrual as of 7/15/07).

Undersøgelsestype

Observationel

Tilmelding (Faktiske)

981

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Forenede Stater
- Alaska
  - Anchorage, Alaska, Forenede Stater, 99508
    - Providence Cancer Center
- Arizona
  - Tucson, Arizona, Forenede Stater, 85724-5024
    - Arizona Cancer Center at University of Arizona Health Sciences Center
- Arkansas
  - Ft. Smith, Arkansas, Forenede Stater, 72903
    - Hembree Mercy Cancer Center at St. Edward Mercy Medical Center
- California
  - Antioch, California, Forenede Stater, 94531
    - Kaiser Permanente - Deer Valley
  - Burbank, California, Forenede Stater, 91505
    - Roy and Patricia Disney Family Cancer Center at Providence Saint Joseph Medical Center
  - Concord, California, Forenede Stater, 94524-4110
    - Cancer Care Center at John Muir Health - Concord Campus
  - Fairfield, California, Forenede Stater, 94533
    - North Bay Cancer Center
  - Fremont, California, Forenede Stater, 94538
    - Kaiser Permanente - Fremont
  - Glendale, California, Forenede Stater, 91204
    - Glendale Memorial Hospital Comprehensive Cancer Center
  - Hayward, California, Forenede Stater, 94545
    - Kaiser Permanente Medical Center - Hayward
  - Marysville, California, Forenede Stater, 95901
    - Tibotec Therapeutics - Division of Ortho Biotech Products, LP
  - Oakland, California, Forenede Stater, 94611
    - Kaiser Permanente Medical Center - Oakland
  - Orange, California, Forenede Stater, 92868
    - Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center
  - Pleasanton, California, Forenede Stater, 94588
    - Valley Care Medical Center
  - Pomona, California, Forenede Stater, 91767
    - Robert and Beverly Lewis Family Cancer Care Center at Pomona Valley Hospital Medical Center
  - Redwood City, California, Forenede Stater, 94063
    - Kaiser Permanente Medical Center - Redwood City
  - Richmond, California, Forenede Stater, 94801
    - Kaiser Permanente Medical Center - Richmond
  - Roseville, California, Forenede Stater, 95661
    - Kaiser Permanente Medical Center - Roseville
  - Sacramento, California, Forenede Stater, 95819
    - Mercy General Hospital
  - Sacramento, California, Forenede Stater, 95817
    - University of California Davis Cancer Center
  - Sacramento, California, Forenede Stater, 95825
    - Kaiser Permanente Medical Center - Sacramento
  - San Francisco, California, Forenede Stater, 94115
    - Kaiser Permanente Medical Center - San Francisco Geary Campus
  - San Jose, California, Forenede Stater, 95119
    - Kaiser Permanente Medical Center - Santa Teresa
  - San Rafael, California, Forenede Stater, 94903
    - Kaiser Foundation Hospital - San Rafael
  - Santa Clara, California, Forenede Stater, 95051
    - Kaiser Permanente Medical Center - Santa Clara Kiely Campus
  - Santa Rosa, California, Forenede Stater, 95403
    - Kaiser Permanente Medical Center - Santa Rosa
  - South San Francisco, California, Forenede Stater, 94080
    - Kaiser Permanente Medical Center - South San Francisco
  - Stockton, California, Forenede Stater, 95210
    - Kaiser Permanente Medical Facility - Stockton
  - Truckee, California, Forenede Stater, 96161
    - Tahoe Forest Cancer Center
  - Vacaville, California, Forenede Stater, 95688
    - Kaiser Permanente Medical Center - Vacaville
  - Vallejo, California, Forenede Stater, 94589
    - Kaiser Permanente Medical Center - Vallejo
  - Walnut Creek, California, Forenede Stater, 94596
    - Kaiser Permanente Medical Center - Walnut Creek
  - Walnut Creek, California, Forenede Stater, 94598
    - John Muir/Mt. Diablo Comprehensive Cancer Center
- Colorado
  - Colorado Springs, Colorado, Forenede Stater, 80909
    - Memorial Hospital Cancer Center - Colorado Springs
  - Denver, Colorado, Forenede Stater, 80205
    - Kaiser Permanente - Denver
  - Fort Collins, Colorado, Forenede Stater, 80524
    - Poudre Valley Hospital
  - Fort Collins, Colorado, Forenede Stater, 80528
    - Front Range Cancer Specialists
  - Lafayette, Colorado, Forenede Stater, 80026
    - Kaiser Permanente - Lafayette
- Connecticut
  - Hartford, Connecticut, Forenede Stater, 06105
    - Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center
- District of Columbia
  - Washington, District of Columbia, Forenede Stater, 20016
    - Sibley Memorial Hospital
- Florida
  - Fort Lauderdale, Florida, Forenede Stater, 33308
    - Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital
  - Jupiter, Florida, Forenede Stater, 33458
    - Ella Milbank Foshay Cancer Center at Jupiter Medical Center
  - Miami Beach, Florida, Forenede Stater, 33140
    - CCOP - Mount Sinai Medical Center
  - Orlando, Florida, Forenede Stater, 32806
    - M.D. Anderson Cancer Center at Orlando
  - Stuart, Florida, Forenede Stater, 34994
    - Robert and Carol Weissman Cancer Center at Martin Memorial
  - Tallahassee, Florida, Forenede Stater, 32308
    - Tallahassee Memorial Hospital
- Georgia
  - Atlanta, Georgia, Forenede Stater, 30309
    - Piedmont Hospital
  - Atlanta, Georgia, Forenede Stater, 30342-1611
    - Northside Hospital Cancer Center
  - Atlanta, Georgia, Forenede Stater, 30342-1701
    - Saint Joseph's Hospital of Atlanta
  - Atlanta, Georgia, Forenede Stater, 30342
    - CCOP - Atlanta Regional
  - Austell, Georgia, Forenede Stater, 30106
    - WellStar Cobb Hospital
  - Columbus, Georgia, Forenede Stater, 31904
    - John B. Amos Cancer Center
  - Decatur, Georgia, Forenede Stater, 30033
    - Charles B. Eberhart Cancer Center at DeKalb Medical Center
  - Fort Gordon, Georgia, Forenede Stater, 30905-5650
    - Dwight David Eisenhower Army Medical Center
  - Gainesville, Georgia, Forenede Stater, 30501
    - Northeast Georgia Medical Center
  - Lawrenceville, Georgia, Forenede Stater, 30045
    - Gwinnett Medical Center
  - Marietta, Georgia, Forenede Stater, 30060
    - Kennestone Cancer Center at Wellstar Kennestone Hospital
  - Riverdale, Georgia, Forenede Stater, 30274-2600
    - Southern Regional Medical Center
  - Rome, Georgia, Forenede Stater, 30165
    - Harbin Clinic Cancer Center - Medical Oncology
  - Savannah, Georgia, Forenede Stater, 31403-3089
    - Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center
  - Savannah, Georgia, Forenede Stater, 31405
    - Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler
- Hawaii
  - Honolulu, Hawaii, Forenede Stater, 96859
    - Tripler Army Medical Center
  - Honolulu, Hawaii, Forenede Stater, 96819
    - Kaiser Permanente - Moanalua Medical Center and Clinic
- Illinois
  - Alton, Illinois, Forenede Stater, 62002
    - Saint Anthony's Hospital at Saint Anthony's Health Center
  - Arlington Heights, Illinois, Forenede Stater, 60005
    - Northwest Community Hospital
  - Aurora, Illinois, Forenede Stater, 60504
    - Rush-Copley Cancer Care Center
  - Chicago, Illinois, Forenede Stater, 60612-7243
    - University of Illinois Cancer Center
  - Chicago, Illinois, Forenede Stater, 60657
    - Creticos Cancer Center at Advocate Illinois Masonic Medical Center
  - Chicago, Illinois, Forenede Stater, 60612
    - Veterans Affairs Medical Center - Chicago Westside Hospital
  - Decatur, Illinois, Forenede Stater, 62526
    - Decatur Memorial Hospital Cancer Care Institute
  - Evanston, Illinois, Forenede Stater, 60201-1781
    - Evanston Hospital
  - Harvey, Illinois, Forenede Stater, 60426
    - Ingalls Cancer Care Center at Ingalls Memorial Hospital
  - La Grange, Illinois, Forenede Stater, 60525
    - La Grange Memorial Hospital
  - Maywood, Illinois, Forenede Stater, 60153
    - Cardinal Bernardin Cancer Center at Loyola University Medical Center
  - Mount Vernon, Illinois, Forenede Stater, 62864
    - Good Samaritan Regional Health Center
  - Naperville, Illinois, Forenede Stater, 60540
    - Edward Hospital Cancer Center
  - Springfield, Illinois, Forenede Stater, 62781-0001
    - Regional Cancer Center at Memorial Medical Center
  - Urbana, Illinois, Forenede Stater, 61801
    - Carle Cancer Center at Carle Foundation Hospital
  - Urbana, Illinois, Forenede Stater, 61801
    - CCOP - Carle Cancer Center
- Indiana
  - Beech Grove, Indiana, Forenede Stater, 46107
    - St. Francis Hospital and Health Centers - Beech Grove Campus
  - Bloomington, Indiana, Forenede Stater, 47403
    - Bloomington Hospital Regional Cancer Institute
  - Michigan City, Indiana, Forenede Stater, 46360
    - Saint Anthony Memorial Health Centers
  - Richmond, Indiana, Forenede Stater, 47374
    - Reid Hospital & Health Care Services
- Iowa
  - Davenport, Iowa, Forenede Stater, 52803
    - Genesis Regional Cancer Center at Genesis Medical Center
  - Mason City, Iowa, Forenede Stater, 50401
    - Mercy Cancer Center at Mercy Medical Center - North Iowa
  - Ottumwa, Iowa, Forenede Stater, 52501
    - McCreery Cancer Center at Ottumwa Regional
  - Sioux City, Iowa, Forenede Stater, 51101
    - Siouxland Hematology-Oncology Associates, LLP
  - Sioux City, Iowa, Forenede Stater, 51104
    - St. Luke's Regional Medical Center
  - Sioux City, Iowa, Forenede Stater, 51104
    - Mercy Medical Center - Sioux City
- Kansas
  - Anthony, Kansas, Forenede Stater, 67003
    - Hospital District Sixth of Harper County
  - Chanute, Kansas, Forenede Stater, 66720
    - Cancer Center of Kansas, PA - Chanute
  - Dodge City, Kansas, Forenede Stater, 67801
    - Cancer Center of Kansas, PA - Dodge City
  - El Dorado, Kansas, Forenede Stater, 67042
    - Cancer Center of Kansas, PA - El Dorado
  - Fort Scott, Kansas, Forenede Stater, 66701
    - Cancer Center of Kansas - Fort Scott
  - Hays, Kansas, Forenede Stater, 67601
    - Hays Medical Center
  - Hutchinson, Kansas, Forenede Stater, 65702
    - Hutchinson Hospital Corporation
  - Independence, Kansas, Forenede Stater, 67301
    - Cancer Center of Kansas-Independence
  - Kansas City, Kansas, Forenede Stater, 66160-7357
    - Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center
  - Kingman, Kansas, Forenede Stater, 67068
    - Cancer Center of Kansas, PA - Kingman
  - Lawrence, Kansas, Forenede Stater, 66044
    - Lawrence Memorial Hospital
  - Liberal, Kansas, Forenede Stater, 67905
    - Cancer Center of Kansas, PA - Liberal
  - Newton, Kansas, Forenede Stater, 67114
    - Cancer Center of Kansas, PA - Newton
  - Overland Park, Kansas, Forenede Stater, 66209
    - Menorah Medical Center
  - Overland Park, Kansas, Forenede Stater, 66213
    - Saint Luke's Hospital - South
  - Parsons, Kansas, Forenede Stater, 67357
    - Cancer Center of Kansas, PA - Parsons
  - Pittsburg, Kansas, Forenede Stater, 66762
    - Mount Carmel Regional Cancer Center
  - Pratt, Kansas, Forenede Stater, 67124
    - Cancer Center of Kansas, PA - Pratt
  - Salina, Kansas, Forenede Stater, 67401
    - Cancer Center of Kansas, PA - Salina
  - Shawnee Mission, Kansas, Forenede Stater, 66204
    - Shawnee Mission Medical Center
  - Topeka, Kansas, Forenede Stater, 66606
    - Cotton-O'Neil Cancer Center
  - Topeka, Kansas, Forenede Stater, 66606
    - St. Francis Comprehensive Cancer Center
  - Wellington, Kansas, Forenede Stater, 67152
    - Cancer Center of Kansas, PA - Wellington
  - Wichita, Kansas, Forenede Stater, 67208
    - Cancer Center of Kansas, PA - Medical Arts Tower
  - Wichita, Kansas, Forenede Stater, 67214
    - Cancer Center of Kansas, PA - Wichita
  - Wichita, Kansas, Forenede Stater, 67214
    - CCOP - Wichita
  - Wichita, Kansas, Forenede Stater, 67214
    - Via Christi Cancer Center at Via Christi Regional Medical Center
  - Wichita, Kansas, Forenede Stater, 67208
    - Associates in Womens Health, PA - North Review
  - Winfield, Kansas, Forenede Stater, 67156
    - Cancer Center of Kansas, PA - Winfield
- Kentucky
  - Ashland, Kentucky, Forenede Stater, 41101-0151
    - Cancer Resource Center at King's Daughters Medical Center
  - Louisville, Kentucky, Forenede Stater, 40202-1886
    - Jewish Hospital
- Louisiana
  - Monroe, Louisiana, Forenede Stater, 71210
    - Louisiana State University Health Sciences Center - Monroe
  - Shreveport, Louisiana, Forenede Stater, 71130-3932
    - Feist-Weiller Cancer Center at Louisiana State University Health Sciences
- Massachusetts
  - Attleboro, Massachusetts, Forenede Stater, 02703
    - Sturdy Memorial Hospital
  - Boston, Massachusetts, Forenede Stater, 02118
    - Boston University Cancer Research Center
  - Brighton, Massachusetts, Forenede Stater, 02135-2997
    - Caritas St. Elizabeth's Medical Center
  - Methuen, Massachusetts, Forenede Stater, 01844
    - Caritas Holy Family Hospital
  - Norwood, Massachusetts, Forenede Stater, 02062
    - Caritas Norwood Hospital
- Michigan
  - Adrian, Michigan, Forenede Stater, 49221
    - Hickman Cancer Center at Bixby Medical Center
  - Ann Arbor, Michigan, Forenede Stater, 48106-0995
    - Saint Joseph Mercy Cancer Center
  - Ann Arbor, Michigan, Forenede Stater, 48106
    - CCOP - Michigan Cancer Research Consortium
  - Bay City, Michigan, Forenede Stater, 48708
    - Bay Regional Medical Center
  - Dearborn, Michigan, Forenede Stater, 48123-2500
    - Oakwood Cancer Center at Oakwood Hospital and Medical Center
  - Escanaba, Michigan, Forenede Stater, 49431
    - Green Bay Oncology, Limited - Escanaba
  - Flint, Michigan, Forenede Stater, 48503
    - Hurley Medical Center
  - Flint, Michigan, Forenede Stater, 48503
    - Genesys Hurley Cancer Institute
  - Grosse Pointe Woods, Michigan, Forenede Stater, 48236
    - Van Elslander Cancer Center at St. John Hospital and Medical Center
  - Iron Mountain, Michigan, Forenede Stater, 49801
    - Dickinson County Healthcare System
  - Jackson, Michigan, Forenede Stater, 49201
    - Foote Memorial Hospital
  - Kalamazoo, Michigan, Forenede Stater, 49007
    - Bronson Methodist Hospital
  - Kalamazoo, Michigan, Forenede Stater, 49001
    - Borgess Medical Center
  - Kalamazoo, Michigan, Forenede Stater, 49007-3731
    - West Michigan Cancer Center
  - Lambertville, Michigan, Forenede Stater, 48144
    - Haematology-Oncology Associates of Ohio and Michigan, PC
  - Lansing, Michigan, Forenede Stater, 48912-1811
    - Sparrow Regional Cancer Center
  - Lansing, Michigan, Forenede Stater, 48910
    - Breslin Cancer Center at Ingham Regional Medical Center
  - Livonia, Michigan, Forenede Stater, 48154
    - St. Mary Mercy Hospital
  - Monroe, Michigan, Forenede Stater, 48162
    - Community Cancer Center of Monroe
  - Monroe, Michigan, Forenede Stater, 48162
    - Mercy Memorial Hospital - Monroe
  - Mount Clemens, Michigan, Forenede Stater, 48043
    - Clemens Regional Medical Center
  - Pontiac, Michigan, Forenede Stater, 48341-2985
    - St. Joseph Mercy Oakland
  - Port Huron, Michigan, Forenede Stater, 48060
    - Mercy Regional Cancer Center at Mercy Hospital
  - Royal Oak, Michigan, Forenede Stater, 48073
    - William Beaumont Hospital - Royal Oak Campus
  - Saginaw, Michigan, Forenede Stater, 48601
    - Seton Cancer Institute at Saint Mary's - Saginaw
  - Southfield, Michigan, Forenede Stater, 48075
    - Providence Cancer Institute at Providence Hospital - Southfield Campus
  - Warren, Michigan, Forenede Stater, 48093
    - St. John Macomb Hospital
- Minnesota
  - Burnsville, Minnesota, Forenede Stater, 55337
    - Fairview Ridges Hospital
  - Coon Rapids, Minnesota, Forenede Stater, 55433
    - Mercy and Unity Cancer Center at Mercy Hospital
  - Duluth, Minnesota, Forenede Stater, 55805
    - CCOP - Duluth
  - Duluth, Minnesota, Forenede Stater, 55805-1983
    - Duluth Clinic Cancer Center - Duluth
  - Duluth, Minnesota, Forenede Stater, 55805
    - Miller - Dwan Medical Center
  - Duluth, Minnesota, Forenede Stater, 55805
    - St. Luke's Hospital Cancer Care Center
  - Edina, Minnesota, Forenede Stater, 55435
    - Fairview Southdale Hospital
  - Fridley, Minnesota, Forenede Stater, 55432
    - Mercy and Unity Cancer Center at Unity Hospital
  - Hutchinson, Minnesota, Forenede Stater, 55350
    - Hutchinson Area Health Care
  - Maplewood, Minnesota, Forenede Stater, 55109
    - Minnesota Oncology Hematology, PA - Maplewood
  - Maplewood, Minnesota, Forenede Stater, 55109
    - HealthEast Cancer Care at St. John's Hospital
  - Minneapolis, Minnesota, Forenede Stater, 55407
    - Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
  - Minneapolis, Minnesota, Forenede Stater, 55415
    - Hennepin County Medical Center - Minneapolis
  - Robbinsdale, Minnesota, Forenede Stater, 55422-2900
    - Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center
  - Rochester, Minnesota, Forenede Stater, 55905
    - Mayo Clinic Cancer Center
  - Saint Louis Park, Minnesota, Forenede Stater, 55416
    - CCOP - Metro-Minnesota
  - Saint Louis Park, Minnesota, Forenede Stater, 55416
    - Park Nicollet Cancer Center
  - Saint Paul, Minnesota, Forenede Stater, 55102
    - United Hospital
  - Shakopee, Minnesota, Forenede Stater, 55379
    - St. Francis Cancer Center at St. Francis Medical Center
  - St. Paul, Minnesota, Forenede Stater, 55101
    - Regions Hospital Cancer Care Center
  - Waconia, Minnesota, Forenede Stater, 55387
    - Ridgeview Medical Center
  - Willmar, Minnesota, Forenede Stater, 56201
    - Willmar Cancer Center at Rice Memorial Hospital
  - Woodbury, Minnesota, Forenede Stater, 55125
    - Minnesota Oncology Hematology, PA - Woodbury
- Mississippi
  - Pascagoula, Mississippi, Forenede Stater, 39581
    - Regional Cancer Center at Singing River Hospital
- Missouri
  - Cape Girardeau, Missouri, Forenede Stater, 63703
    - Saint Francis Medical Center
  - Kansas City, Missouri, Forenede Stater, 64131
    - CCOP - Kansas City
  - Kansas City, Missouri, Forenede Stater, 64116
    - North Kansas City Hospital
  - Kansas City, Missouri, Forenede Stater, 64132
    - Research Medical Center
  - Kansas City, Missouri, Forenede Stater, 64108
    - Truman Medical Center - Hospital Hill
  - Kansas City, Missouri, Forenede Stater, 64111
    - Saint Luke's Cancer Institute at Saint Luke's Hospital
  - Kansas City, Missouri, Forenede Stater, 64114
    - St. Joseph Medical Center
  - Kansas City, Missouri, Forenede Stater, 64118
    - Heartland Hematology Oncology Associates, Incorporated
  - Lee's Summit, Missouri, Forenede Stater, 64086
    - Saint Luke's East - Lee's Summit
  - Liberty, Missouri, Forenede Stater, 64068
    - Liberty Hospital
  - Saint Joseph, Missouri, Forenede Stater, 64506
    - Heartland Regional Medical Center
  - Saint Joseph, Missouri, Forenede Stater, 64507
    - Saint Joseph Oncology, Incorporated
  - Saint Louis, Missouri, Forenede Stater, 63131
    - Missouri Baptist Cancer Center
  - Saint Louis, Missouri, Forenede Stater, 63141
    - CCOP - St. Louis-Cape Girardeau
  - Saint Louis, Missouri, Forenede Stater, 63141
    - Arch Medical Services, Incorporated at Center for Cancer Care and Research
  - Saint Louis, Missouri, Forenede Stater, 63110
    - Saint Louis University Cancer Center
  - Saint Louis, Missouri, Forenede Stater, 63109
    - Midwest Hematology Oncology Group, Incorporated
  - Saint Louis, Missouri, Forenede Stater, 63141
    - David C. Pratt Cancer Center at St. John's Mercy
  - Saint Louis, Missouri, Forenede Stater, 63141
    - Comprehensive Cancer Care, PC
  - Springfield, Missouri, Forenede Stater, 65802
    - CCOP - Cancer Research for the Ozarks
  - Springfield, Missouri, Forenede Stater, 65804
    - St. John's Regional Health Center
  - Springfield, Missouri, Forenede Stater, 65807
    - Hulston Cancer Center at Cox Medical Center South
- Montana
  - Billings, Montana, Forenede Stater, 59101
    - CCOP - Montana Cancer Consortium
  - Billings, Montana, Forenede Stater, 59101
    - Northern Rockies Radiation Oncology Center
  - Billings, Montana, Forenede Stater, 59101
    - St. Vincent Healthcare Cancer Care Services
  - Billings, Montana, Forenede Stater, 59107-7000
    - Billings Clinic - Downtown
  - Billings, Montana, Forenede Stater, 59102
    - Hematology-Oncology Centers of the Northern Rockies - Billings
  - Bozeman, Montana, Forenede Stater, 59715
    - Bozeman Deaconess Cancer Center
  - Butte, Montana, Forenede Stater, 59701
    - St. James Healthcare Cancer Care
  - Great Falls, Montana, Forenede Stater, 59405
    - Great Falls Clinic - Main Facility
  - Great Falls, Montana, Forenede Stater, 59405
  - Great Falls, Montana, Forenede Stater, 59405-5309
    - Big Sky Oncology
  - Great Falls, Montana, Forenede Stater, 59405
    - Sletten Cancer Institute at Benefis Healthcare
  - Havre, Montana, Forenede Stater, 59501
    - Northern Montana Hospital
  - Helena, Montana, Forenede Stater, 59601
    - St. Peter's Hospital
  - Kalispell, Montana, Forenede Stater, 59901
    - Glacier Oncology, PLLC
  - Kalispell, Montana, Forenede Stater, 59901
    - Kalispell Medical Oncology at KRMC
  - Missoula, Montana, Forenede Stater, 59804
    - Guardian Oncology and Center for Wellness
  - Missoula, Montana, Forenede Stater, 59807-7877
    - Montana Cancer Specialists at Montana Cancer Center
  - Missoula, Montana, Forenede Stater, 59807
    - Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
- Nebraska
  - Omaha, Nebraska, Forenede Stater, 68114
    - Methodist Estabrook Cancer Center
- New Hampshire
  - Concord, New Hampshire, Forenede Stater, 03301
    - New Hampshire Oncology - Hematology, PA at Payson Center for Cancer Care
  - Hooksett, New Hampshire, Forenede Stater, 03106
    - New Hampshire Oncology - Hematology, PA - Hooksett
  - Laconia, New Hampshire, Forenede Stater, 03246
    - Lakes Region General Hospital
  - Manchester, New Hampshire, Forenede Stater, 03103
    - Elliot Regional Cancer Center at Elliot Hospital
- New Jersey
  - New Brunswick, New Jersey, Forenede Stater, 08901
    - Saint Peter's University Hospital
- New York
  - Buffalo, New York, Forenede Stater, 14263-0001
    - Roswell Park Cancer Institute
  - Manhasset, New York, Forenede Stater, 11030
    - CCOP - North Shore University Hospital
  - Manhasset, New York, Forenede Stater, 11030
    - Don Monti Comprehensive Cancer Center at North Shore University Hospital
  - Mineola, New York, Forenede Stater, 11501
    - Winthrop University Hospital
  - New Hyde Park, New York, Forenede Stater, 11040
    - Long Island Jewish Medical Center
  - New York, New York, Forenede Stater, 10032
    - Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center
  - New York, New York, Forenede Stater, 10025
    - St. Luke's - Roosevelt Hospital Center - St.Luke's Division
  - New York, New York, Forenede Stater, 10003-3803
    - Beth Israel Medical Center - Petrie Division
  - Rochester, New York, Forenede Stater, 14642
    - James P. Wilmot Cancer Center at University of Rochester Medical Center
  - Rochester, New York, Forenede Stater, 14620
    - Highland Hospital of Rochester
  - Rochester, New York, Forenede Stater, 14621
    - Lipson Cancer and Blood Center at Rochester General Hospital
  - Syracuse, New York, Forenede Stater, 13210
    - SUNY Upstate Medical University Hospital
- North Carolina
  - Asheville, North Carolina, Forenede Stater, 28801
    - Mission Hospitals - Memorial Campus
  - Charlotte, North Carolina, Forenede Stater, 28233-3549
    - Presbyterian Cancer Center at Presbyterian Hospital
  - Gastonia, North Carolina, Forenede Stater, 28053
    - CaroMont Cancer Center at Gaston Memorial Hospital
  - Goldsboro, North Carolina, Forenede Stater, 27534
    - Wayne Memorial Hospital, Incorporated
  - Hendersonville, North Carolina, Forenede Stater, 28791
    - Pardee Memorial Hospital
  - High Point, North Carolina, Forenede Stater, 27261
    - High Point Regional Hospital
- North Dakota
  - Bismarck, North Dakota, Forenede Stater, 58501
    - Bismarck Cancer Center
  - Bismarck, North Dakota, Forenede Stater, 58501
    - Medcenter One Hospital Cancer Care Center
  - Bismarck, North Dakota, Forenede Stater, 58501
    - Mid Dakota Clinic, PC
  - Bismarck, North Dakota, Forenede Stater, 58502
    - St. Alexius Medical Center Cancer Center
  - Minot, North Dakota, Forenede Stater, 58701
    - Trinity Cancercare Center
- Ohio
  - Akron, Ohio, Forenede Stater, 44307
    - McDowell Cancer Center at Akron General Medical Center
  - Akron, Ohio, Forenede Stater, 44309-2090
    - Summa Center for Cancer Care at Akron City Hospital
  - Barberton, Ohio, Forenede Stater, 44203
    - Barberton Citizens Hospital
  - Bellefontaine, Ohio, Forenede Stater, 43311
    - Mary Rutan Hospital
  - Bowling Green, Ohio, Forenede Stater, 43402
    - Wood County Oncology Center
  - Canton, Ohio, Forenede Stater, 44710-1799
    - Aultman Cancer Center at Aultman Hospital
  - Canton, Ohio, Forenede Stater, 44708
    - Mercy Cancer Center at Mercy Medical Center
  - Chillicothe, Ohio, Forenede Stater, 45601
    - Adena Regional Medical Center
  - Cincinnati, Ohio, Forenede Stater, 45242
    - Bethesda North Hospital
  - Cincinnati, Ohio, Forenede Stater, 45220
    - Good Samaritan Hospital Cancer Treatment Center
  - Clyde, Ohio, Forenede Stater, 43410
    - North Coast Cancer Care - Clyde
  - Columbus, Ohio, Forenede Stater, 43214-3998
    - Riverside Methodist Hospital Cancer Care
  - Columbus, Ohio, Forenede Stater, 43222
    - Mount Carmel Health - West Hospital
  - Columbus, Ohio, Forenede Stater, 43215
    - CCOP - Columbus
  - Columbus, Ohio, Forenede Stater, 43215
    - Grant Medical Center Cancer Care
  - Columbus, Ohio, Forenede Stater, 43228
    - Doctors Hospital at Ohio Health
  - Dayton, Ohio, Forenede Stater, 45405
    - Grandview Hospital
  - Dayton, Ohio, Forenede Stater, 45406
    - Good Samaritan Hospital
  - Dayton, Ohio, Forenede Stater, 45409
    - David L. Rike Cancer Center at Miami Valley Hospital
  - Dayton, Ohio, Forenede Stater, 45415
    - Samaritan North Cancer Care Center
  - Dayton, Ohio, Forenede Stater, 45420
    - CCOP - Dayton
  - Delaware, Ohio, Forenede Stater, 43015
    - Grady Memorial Hospital
  - Elyria, Ohio, Forenede Stater, 44035
    - Community Cancer Center
  - Elyria, Ohio, Forenede Stater, 44035
    - Hematology Oncology Center
  - Findlay, Ohio, Forenede Stater, 45840
    - Blanchard Valley Medical Associates
  - Franklin, Ohio, Forenede Stater, 45005-1066
    - Middletown Regional Hospital
  - Greenville, Ohio, Forenede Stater, 45331
    - Wayne Hospital
  - Kettering, Ohio, Forenede Stater, 45429
    - Charles F. Kettering Memorial Hospital
  - Lancaster, Ohio, Forenede Stater, 43130
    - Fairfield Medical Center
  - Lima, Ohio, Forenede Stater, 45804
    - Lima Memorial Hospital
  - Lima, Ohio, Forenede Stater, 45801
    - St. Rita's Medical Center
  - Marietta, Ohio, Forenede Stater, 45750
    - Strecker Cancer Center at Marietta Memorial Hospital
  - Maumee, Ohio, Forenede Stater, 43537-1839
    - Northwest Ohio Oncology Center
  - Mount Vernon, Ohio, Forenede Stater, 43050
    - Knox Community Hospital
  - Newark, Ohio, Forenede Stater, 43055
    - Licking Memorial Cancer Care Program at Licking Memorial Hospital
  - Norwalk, Ohio, Forenede Stater, 44857
    - Fisher-Titus Medical Center
  - Oregon, Ohio, Forenede Stater, 43616
    - St. Charles Mercy Hospital
  - Oregon, Ohio, Forenede Stater, 43616
    - Toledo Clinic - Oregon
  - Salem, Ohio, Forenede Stater, 44460
    - Cancer Care Center, Incorporated
  - Sandusky, Ohio, Forenede Stater, 44870
    - North Coast Cancer Care, Incorporated
  - Springfield, Ohio, Forenede Stater, 45505
    - Community Hospital of Springfield and Clark County
  - Sylvania, Ohio, Forenede Stater, 43560
    - Flower Hospital Cancer Center
  - Tiffin, Ohio, Forenede Stater, 44883
    - Mercy Hospital of Tiffin
  - Toledo, Ohio, Forenede Stater, 43608
    - St. Vincent Mercy Medical Center
  - Toledo, Ohio, Forenede Stater, 43606
    - Toledo Hospital
  - Toledo, Ohio, Forenede Stater, 43614
    - Medical University of Ohio Cancer Center
  - Toledo, Ohio, Forenede Stater, 43617
    - CCOP - Toledo Community Hospital
  - Toledo, Ohio, Forenede Stater, 43623
    - Toledo Clinic, Incorporated - Main Clinic
  - Toledo, Ohio, Forenede Stater, 43623
    - St. Anne Mercy Hospital
  - Troy, Ohio, Forenede Stater, 45373-1300
    - UVMC Cancer Care Center at Upper Valley Medical Center
  - Wauseon, Ohio, Forenede Stater, 43567
    - Fulton County Health Center
  - Westerville, Ohio, Forenede Stater, 43081
    - Mount Carmel St. Ann's Cancer Center
  - Wooster, Ohio, Forenede Stater, 44691
    - Cancer Treatment Center
  - Wright-Patterson Afb, Ohio, Forenede Stater, 45433-5529
    - United States Air Force Medical Center - Wright-Patterson
  - Xenia, Ohio, Forenede Stater, 45385
    - Ruth G. McMillan Cancer Center at Greene Memorial Hospital
  - Zanesville, Ohio, Forenede Stater, 43701
    - Genesis - Good Samaritan Hospital
- Oregon
  - Clackamas, Oregon, Forenede Stater, 97015
    - Clackamas Radiation Oncology Center
  - Milwaukie, Oregon, Forenede Stater, 97222
    - Providence Milwaukie Hospital
  - Newberg, Oregon, Forenede Stater, 97132
    - Providence Newberg Medical Center
  - Oregon City, Oregon, Forenede Stater, 97045
    - Willamette Falls Hospital
  - Portland, Oregon, Forenede Stater, 97239-3098
    - Knight Cancer Institute At Oregon Health and Science University
  - Portland, Oregon, Forenede Stater, 97216
    - Adventist Medical Center
  - Portland, Oregon, Forenede Stater, 97213-2967
    - Providence Cancer Center at Providence Portland Medical Center
  - Portland, Oregon, Forenede Stater, 97225
    - CCOP - Columbia River Oncology Program
  - Portland, Oregon, Forenede Stater, 97225
    - Providence St. Vincent Medical Center
- Pennsylvania
  - Allentown, Pennsylvania, Forenede Stater, 18105
    - Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest
  - Pittsburgh, Pennsylvania, Forenede Stater, 15212
    - Allegheny Cancer Center at Allegheny General Hospital
  - Pittsburgh, Pennsylvania, Forenede Stater, 15224-1791
    - Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital
- South Carolina
  - Anderson, South Carolina, Forenede Stater, 29621
    - AnMed Cancer Center
  - Easley, South Carolina, Forenede Stater, 29640
    - Cancer Centers of the Carolinas - Easley
  - Greenville, South Carolina, Forenede Stater, 29615
    - CCOP - Greenville
  - Greenville, South Carolina, Forenede Stater, 29605
    - Greenville Hospital Cancer Center
  - Greenville, South Carolina, Forenede Stater, 29615
    - Cancer Centers of the Carolinas - Eastside
  - Greenville, South Carolina, Forenede Stater, 29605
    - Cancer Centers of the Carolinas - Faris Road
  - Greenville, South Carolina, Forenede Stater, 29605
    - Cancer Centers of the Carolinas - Grove Commons
  - Greenville, South Carolina, Forenede Stater, 29601
    - Bon Secours St. Francis Health System
  - Greenwood, South Carolina, Forenede Stater, 29646
    - Self Regional Cancer Center at Self Regional Medical Center
  - Greer, South Carolina, Forenede Stater, 29650
    - Cancer Centers of the Carolinas - Greer Medical Oncology
  - Greer, South Carolina, Forenede Stater, 29650
    - Cancer Centers of the Carolinas - Greer Radiation Oncology
  - Seneca, South Carolina, Forenede Stater, 29672
    - Cancer Centers of the Carolinas - Seneca
  - Spartanburg, South Carolina, Forenede Stater, 29303
    - CCOP - Upstate Carolina
  - Spartanburg, South Carolina, Forenede Stater, 29303
    - Gibbs Regional Cancer Center at Spartanburg Regional Medical Center
  - Spartanburg, South Carolina, Forenede Stater, 29307
    - Cancer Centers of the Carolinas - Spartanburg
- South Dakota
  - Sioux Falls, South Dakota, Forenede Stater, 57105
    - Medical X-Ray Center, PC
  - Sioux Falls, South Dakota, Forenede Stater, 57117-5039
    - Sanford Cancer Center at Sanford USD Medical Center
- Tennessee
  - Chattanooga, Tennessee, Forenede Stater, 37404
    - H. Clay Evans Johnson Cancer Center at Memorial Hospital
  - Knoxville, Tennessee, Forenede Stater, 37916
    - Thompson Cancer Survival Center
  - Knoxville, Tennessee, Forenede Stater, 37920-6999
    - U.T. Medical Center Cancer Institute
- Utah
  - American Fork, Utah, Forenede Stater, 84003
    - American Fork Hospital
  - Cedar City, Utah, Forenede Stater, 84720
    - Sandra L. Maxwell Cancer Center
  - Logan, Utah, Forenede Stater, 84321
    - Logan Regional Hospital
  - Murray, Utah, Forenede Stater, 84157
    - Jon and Karen Huntsman Cancer Center at Intermountain Medical Center
  - Ogden, Utah, Forenede Stater, 84403
    - Val and Ann Browning Cancer Center at McKay-Dee Hospital Center
  - Provo, Utah, Forenede Stater, 84604
    - Utah Valley Regional Medical Center - Provo
  - Saint George, Utah, Forenede Stater, 84770
    - Dixie Regional Medical Center - East Campus
  - Salt Lake City, Utah, Forenede Stater, 84112
    - Huntsman Cancer Institute at University of Utah
  - Salt Lake City, Utah, Forenede Stater, 84103
    - LDS Hospital
  - Salt Lake City, Utah, Forenede Stater, 84106
    - Utah Cancer Specialists at UCS Cancer Center
- Vermont
  - Berlin, Vermont, Forenede Stater, 05602
    - Mountainview Medical
  - Burlington, Vermont, Forenede Stater, 05401
    - Fletcher Allen Health Care - University Health Center Campus
- Virginia
  - Charlottesville, Virginia, Forenede Stater, 22901
    - Martha Jefferson Hospital Cancer Care Center
  - Danville, Virginia, Forenede Stater, 24541
    - Danville Regional Medical Center
  - Fredericksburg, Virginia, Forenede Stater, 22401
    - Fredericksburg Oncology, Incorporated
- Washington
  - Bellingham, Washington, Forenede Stater, 98225
    - St. Joseph Cancer Center
  - Bremerton, Washington, Forenede Stater, 98310
    - Olympic Hematology and Oncology
  - Centralia, Washington, Forenede Stater, 98531-9027
    - Providence Centralia Hospital
  - Federal Way, Washington, Forenede Stater, 98003
    - St. Francis Hospital
  - Kennewick, Washington, Forenede Stater, 99336
    - Columbia Basin Hematology
  - Mt. Vernon, Washington, Forenede Stater, 98273
    - Skagit Valley Hospital Cancer Care Center
  - Olympia, Washington, Forenede Stater, 98506-5166
    - Providence St. Peter Hospital Regional Cancer Center
  - Poulsbo, Washington, Forenede Stater, 98370
    - Harrison Poulsbo Hematology and Onocology
  - Puyallup, Washington, Forenede Stater, 98372
    - Good Samaritan Cancer Center
  - Seattle, Washington, Forenede Stater, 98109
    - Fred Hutchinson Cancer Research Center
  - Seattle, Washington, Forenede Stater, 98104
    - Harborview Medical Center
  - Seattle, Washington, Forenede Stater, 98104
    - Minor and James Medical, PLLC
  - Seattle, Washington, Forenede Stater, 98112
    - Group Health Central Hospital
  - Seattle, Washington, Forenede Stater, 98122-4307
    - Swedish Cancer Institute at Swedish Medical Center - First Hill Campus
  - Seattle, Washington, Forenede Stater, 98122
    - Polyclinic First Hill
  - Seattle, Washington, Forenede Stater, 98195
    - University Cancer Center at University of Washington Medical Center
  - Spokane, Washington, Forenede Stater, 99202
    - Cancer Care Northwest - Spokane South
  - Spokane, Washington, Forenede Stater, 99218
    - Evergreen Hematology and Oncology, PS
  - Tacoma, Washington, Forenede Stater, 98405-3004
    - Franciscan Cancer Center at St. Joseph Medical Center
  - Tacoma, Washington, Forenede Stater, 98405
    - Allenmore Hospital
  - Tacoma, Washington, Forenede Stater, 98405
    - CCOP - Northwest
  - Tacoma, Washington, Forenede Stater, 98405
    - MultiCare Regional Cancer Center at Tacoma General Hospital
  - Tacoma, Washington, Forenede Stater, 98499
    - St. Clare Hospital
  - Tacoma, Washington, Forenede Stater, 98431
    - Madigan Army Medical Center - Tacoma
  - Vancouver, Washington, Forenede Stater, 98684
    - Northwest Cancer Specialists at Vancouver Cancer Center
  - Vancouver, Washington, Forenede Stater, 98668
    - Southwest Washington Medical Center Cancer Center
  - Wenatchee, Washington, Forenede Stater, 98801-2028
    - Wenatchee Valley Medical Center
- Wisconsin
  - Chippewa Falls, Wisconsin, Forenede Stater, 54729
    - Marshfield Clinic - Chippewa Center
  - Eau Claire, Wisconsin, Forenede Stater, 54701
    - Center for Cancer Treatment & Prevention at Sacred Heart Hospital
  - Eau Claire, Wisconsin, Forenede Stater, 54701
    - Marshfield Clinic Cancer Care at Regional Cancer Center
  - Green Bay, Wisconsin, Forenede Stater, 54307-3508
    - St. Vincent Hospital Regional Cancer Center
  - Green Bay, Wisconsin, Forenede Stater, 54301-3526
    - Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center
  - Green Bay, Wisconsin, Forenede Stater, 54303
    - Green Bay Oncology, Limited at St. Mary's Hospital
  - Green Bay, Wisconsin, Forenede Stater, 54303
    - St. Mary's Hospital Medical Center - Green Bay
  - Manitowoc, Wisconsin, Forenede Stater, 54221-1450
    - Holy Family Memorial Medical Center Cancer Care Center
  - Marinette, Wisconsin, Forenede Stater, 54143
    - Bay Area Cancer Care Center at Bay Area Medical Center
  - Marshfield, Wisconsin, Forenede Stater, 54449
    - Saint Joseph's Hospital
  - Marshfield, Wisconsin, Forenede Stater, 54449
    - Marshfield Clinic - Marshfield Center
  - Milwaukee, Wisconsin, Forenede Stater, 53295
    - Veterans Affairs Medical Center - Milwaukee
  - Milwaukee, Wisconsin, Forenede Stater, 53215
    - Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical Center
  - Minocqua, Wisconsin, Forenede Stater, 54548
    - Marshfield Clinic - Lakeland Center
  - Oconto Falls, Wisconsin, Forenede Stater, 54154
    - Green Bay Oncology, Limited - Oconto Falls
  - Racine, Wisconsin, Forenede Stater, 53405
    - All Saints Cancer Center at Wheaton Franciscan Healthcare
  - Rhinelander, Wisconsin, Forenede Stater, 54501
    - Ministry Medical Group at Saint Mary's Hospital
  - Rice Lake, Wisconsin, Forenede Stater, 54868
    - Marshfield Clinic - Indianhead Center
  - Stevens Point, Wisconsin, Forenede Stater, 54481
    - Marshfield Clinic at Saint Michael's Hospital
  - Stevens Point, Wisconsin, Forenede Stater, 54481
    - Saint Michael's Hospital Cancer Center
  - Sturgeon Bay, Wisconsin, Forenede Stater, 54235
    - Green Bay Oncology, Limited - Sturgeon Bay
  - Wausau, Wisconsin, Forenede Stater, 54401
    - Marshfield Clinic - Wausau Center
  - West Allis, Wisconsin, Forenede Stater, 53227
    - West Allis Memorial Hospital
  - Weston, Wisconsin, Forenede Stater, 54476
    - Diagnostic and Treatment Center
  - Weston, Wisconsin, Forenede Stater, 54476
    - Marshfield Clinic - Weston Center
  - Wisconsin Rapids, Wisconsin, Forenede Stater, 54494
    - Marshfield Clinic - Wisconsin Rapids Center
- Wyoming
  - Casper, Wyoming, Forenede Stater, 82609
    - Rocky Mountain Oncology
  - Sheridan, Wyoming, Forenede Stater, 82801
    - Welch Cancer Center at Sheridan Memorial Hospital

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

18 år til 120 år (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Køn, der er berettiget til at studere

Alle

Prøveudtagningsmetode

Ikke-sandsynlighedsprøve

Studiebefolkning

Cancer center

Beskrivelse

DISEASE CHARACTERISTICS:

Histologically confirmed non-small cell lung cancer
- Stage I, II, IIIA, or IIIB (T4 or N3) disease
- No malignant pleural effusion; if pleural fluid is present, 1 of the following criteria must be met:
  - Benign pleural fluid
  - Pleural fluid is due to prior thoracotomy
  - Pleural fluid is deemed too small to safely tap
- No diagnosis by cytology alone
Newly diagnosed disease
Must have tumor blocks/slides available and must be willing to provide tissue samples
Prior smoking history meeting 1 of the following criteria:
- Never smoker, defined as < 100 cigarettes in lifetime
- Former smoker, defined as no smoking for ≥ 1 year
- Current smoker, defined as all others (closed to accrual as of 7/15/07)
No pericardial effusions

PATIENT CHARACTERISTICS:

No other prior malignancy except for 1 of the following:
- Adequately treated basal cell or squamous cell skin cancer
- In situ cervical cancer
- Other cancer for which the patient has been disease free for five years

PRIOR CONCURRENT THERAPY:

No prior chemotherapy or radiotherapy
Concurrent participation in therapeutic trials allowed

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Antal grupper/kohorter

Kohorter og interventioner

Gruppe / kohorte	Intervention / Behandling
Male, Never-smokers Male subjects who smoked less than 100 cigarettes during their lifetime.	Genetisk: genekspressionsanalyse Genetisk: polymorfi analyse Andet: laboratoriebiomarkøranalyse Genetisk: mutationsanalyse Procedure: undersøgelse af højrisikofaktorer Andet: immunhistokemi farvningsmetode Andet: undersøgelse af socioøkonomiske og demografiske variabler Andet: fluorescerende antistof teknik Genetisk: polymerase kædereaktion Andet: matrix-assisteret laserdesorption/ioniseringstid for flyvemassespektrometri Genetisk: chromogenic in situ hybridization
Male, Ever-smokers Male subjects who have smoked at least 100 cigarettes during their lifetime.	Genetisk: genekspressionsanalyse Genetisk: polymorfi analyse Andet: laboratoriebiomarkøranalyse Genetisk: mutationsanalyse Procedure: undersøgelse af højrisikofaktorer Andet: immunhistokemi farvningsmetode Andet: undersøgelse af socioøkonomiske og demografiske variabler Andet: fluorescerende antistof teknik Genetisk: polymerase kædereaktion Andet: matrix-assisteret laserdesorption/ioniseringstid for flyvemassespektrometri Genetisk: chromogenic in situ hybridization
Female, Ever-smokers Female subjects who have smoked less than 100 cigarettes during their lifetime.	Genetisk: genekspressionsanalyse Genetisk: polymorfi analyse Andet: laboratoriebiomarkøranalyse Genetisk: mutationsanalyse Procedure: undersøgelse af højrisikofaktorer Andet: immunhistokemi farvningsmetode Andet: undersøgelse af socioøkonomiske og demografiske variabler Andet: fluorescerende antistof teknik Genetisk: polymerase kædereaktion Andet: matrix-assisteret laserdesorption/ioniseringstid for flyvemassespektrometri Genetisk: chromogenic in situ hybridization
Female, Never-smokers Female subjects who have smoked at least 100 cigarettes during their lifetime.	Genetisk: genekspressionsanalyse Genetisk: polymorfi analyse Andet: laboratoriebiomarkøranalyse Genetisk: mutationsanalyse Procedure: undersøgelse af højrisikofaktorer Andet: immunhistokemi farvningsmetode Andet: undersøgelse af socioøkonomiske og demografiske variabler Andet: fluorescerende antistof teknik Genetisk: polymerase kædereaktion Andet: matrix-assisteret laserdesorption/ioniseringstid for flyvemassespektrometri Genetisk: chromogenic in situ hybridization

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål	Tidsramme
DNA adduct levels Tidsramme: End of study	End of study
Tumor tissue alterations Tidsramme: End of study	End of study

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Southwest Oncology Group

Samarbejdspartnere

National Cancer Institute (NCI)

Efterforskere

Studiestol: Christine B. Ambrosone, PhD, Roswell Park Cancer Institute
Studiestol: Regina M. Santella, PhD, Herbert Irving Comprehensive Cancer Center
Studiestol: Paul H. Gumerlock, PhD, University of California, Davis

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart

1. oktober 2005

Primær færdiggørelse (Faktiske)

1. juli 2012

Studieafslutning (Faktiske)

1. juli 2012

Datoer for studieregistrering

Først indsendt

20. marts 2007

Først indsendt, der opfyldte QC-kriterier

20. marts 2007

Først opslået (Skøn)

22. marts 2007

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Skøn)

26. oktober 2015

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

23. oktober 2015

Sidst verificeret

1. december 2013

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

CDR0000446084
U10CA032102 (U.S. NIH-bevilling/kontrakt)
S0424 (Anden identifikator: SWOG)

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Kliniske forsøg med Lungekræft

Mansoura University

Rekruttering

Sammenligning af tre metoder til PEEP-titrering under én lungeventilation i liggende stilling

One Lung Ventilation

Egypten
Chinese Chronic Respiratory Disease Research Network

Rekruttering

Kohorteundersøgelse af lungeknudeintervention (LNICS)

Hændelse Lung Nodule

Kina
Dokuz Eylul University

Afsluttet

Evaluering af en lungeventilation med ultralyd ved thoraxkirurgiske operationer

One Lung Ventilation

Kalkun
Seoul National University Hospital

Afsluttet

Effektiviteten af Lung Sono i One-lung Ventilation

One Lung Ventilation

Korea, Republikken
Seoul National University Hospital

Afsluttet

Forkonditionering af One-lung Ventilation

One Lung Ventilation

Korea, Republikken
Yonsei University

Afsluttet

Positivt endeekspiratorisk tryk og alveolær rekruttering til én lungeventilation

One Lung Ventilation

Korea, Republikken
Sichuan University
West China Hospital

Midlertidigt ikke tilgængelig

Ændringen af pulmonal blodgennemstrømning under én lungeventilation

One Lung Ventilation
Joseph D. Tobias

Afsluttet

Intracuff-tryk under en-lungeventilation hos spædbørn og børn

One-lung Ventilation (OLV)

Forenede Stater
University Health Network, Toronto

Aktiv, ikke rekrutterende

TorEx lungeperfusionssystem

Lungetransplantation | Ex Vivo Lung Perfusion

Canada
Papa Giovanni XXIII Hospital

Afsluttet

Ex Vivo Lungeperfusion i Bergamo Lungetransplantationsprogram

Lungetransplantation | Ex Vivo Lung Perfusion

Italien

Kliniske forsøg med genekspressionsanalyse

Pusan National University Hospital

Afsluttet

Mikro-ekspression læsefærdighedstræning hos medicinstuderende

Meddelelse
Liao Jian An

Rekruttering

Meridianenergiændringer hos patienter med hoved- og nakkekræft efter kemoterapi eller strålebehandling

Hoved- og halskræft

Taiwan
Fondation Lenval

Trukket tilbage

Indflydelse af træthed på gangmønsteret hos patienter med cerebral parese.

Cerebral Parese

Frankrig
Daniel Maroti
Wayne State University

Rekruttering

Internetbaseret følelsesmæssig bevidsthed og udtryksterapi for funktionel somatisk lidelse med og uden terapeutstøtte

Somatisk symptomlidelse | Funktionel somatisk lidelse | Funktionelle somatiske syndromer

Sverige
Kessler Foundation

Ikke rekrutterer endnu

En styrkebaseret indsats for at forbedre jobsamtalefærdigheder hos unge voksne i et lokalsamfund

Autismespektrumforstyrrelse
Candela Corporation

Rekruttering

Klinisk undersøgelse, der evaluerer Nordlys™ SWT IPL for Dry Eye Disease (DED) på grund af MGD

Meibomisk kirtel dysfunktion | Tør øjensygdom

Forenede Stater, Argentina
IRCCS Eugenio Medea

Rekruttering

Biomarkørers baner for tidlig intervention hos søskende til børn med autismespektrumforstyrrelse

Autismespektrumforstyrrelse | Tidlig indsats

Italien
Oregon Health and Science University
4DMedical

Tilmelding efter invitation

Ventilationsubalancer ved let til moderat kronisk obstruktiv lungesygdom (VAPOR)

Lungesygdomme | KOL | Luftvejssygdom | Dyspnø

Forenede Stater
IRCCS Eugenio Medea

Rekruttering

Bekræft præstationen i klinisk praksis af den fordybende Virtual Reality Platform GRAIL (Gait Real-time Analysis Interactive Lab)

Cerebral Parese | Erhvervet hjerneskade

Italien
Muğla Sıtkı Koçman University

Afsluttet

Autofagi markører i endometriepolypper

Endometriepolyp | Autofagi

Kalkun

S0424 - Carcinogens in Lung Tissue From Smokers (Closed to Entry as of 7/15/07) and Non-Smokers With Newly Diagnosed Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer

Molecular Epidemiology Case-Series Study of Non-Small Cell Lung Cancer in Smoking and Non-Smoking Women and Men

Studieoversigt

Status

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

Undersøgelsestype

Tilmelding (Faktiske)

Kontakter og lokationer

Studiesteder

Deltagelseskriterier

Berettigelseskriterier

Aldre berettiget til at studere

Tager imod sunde frivillige

Køn, der er berettiget til at studere

Prøveudtagningsmetode

Studiebefolkning

Beskrivelse

Studieplan

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Antal grupper/kohorter

Kohorter og interventioner

Gruppe / kohorte

Intervention / Behandling

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål

Tidsramme

Samarbejdspartnere og efterforskere

Sponsor

Samarbejdspartnere

Efterforskere

Datoer for undersøgelser

Studer store datoer

Studiestart

Primær færdiggørelse (Faktiske)

Studieafslutning (Faktiske)

Datoer for studieregistrering

Først indsendt

Først indsendt, der opfyldte QC-kriterier

Først opslået (Skøn)

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Skøn)

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

Sidst verificeret

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

Kliniske forsøg med Lungekræft

Kliniske forsøg med genekspressionsanalyse

Søg i lignende forsøg

Sponsorer og samarbejdspartnere

Medicinske tilstande

Narkotikainterventioner

CROs by country

CROs in Mali

Betingelser

Sjældne sygdomme

Narkotikainterventioner

Kosttilskud

Sponsor / samarbejdspartnere

Placeringer