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En undersøgelse for at teste, om BI 690517 i kombination med Empagliflozin hjælper mennesker med hjertesvigt

27. oktober 2026 opdateret af: Boehringer Ingelheim

Et fase III dobbeltblindt, randomiseret, parallelgruppeoverlegenhedsforsøg til evaluering af effektivitet og sikkerhed af den kombinerede brug af Oral BI 690517 og Empagliflozin sammenlignet med placebo og Empagliflozin hos patienter med hjertesvigt (HF) (New York Heart Association [NYHA] Klasse II til IV) og venstre ventrikulær ejektionsfraktion (LVEF) ≥40 %

This study is open to adults aged 18 or above legal age with heart failure. People can join the study if they have heart failure symptoms and a left ventricular ejection fraction (LVEF) of 40% or more. The purpose of this study is to find out whether vicadrostat (BI 690517) in combination with empagliflozin helps people with heart failure.

Participants are put into 2 groups by chance. Every participant has an equal chance of being in each group. The groups are:

  • Vicadrostat/empagliflozin group: participants take vicadrostat/empagliflozin as tablets once a day.
  • Placebo/empagliflozin group: participants take placebo/empagliflozin as tablets once a day.

Participants can stay in the study as long as they benefit from treatment and can tolerate it. During this time, they visit their doctors regularly. The doctors regularly check participants' health and take note of any unwanted effects. The study staff may also contact the participants by phone. Participants also regularly answer questions about their well-being.

The study does not have a fixed duration. It continues until there is enough data to see if the treatment is working.

Studieoversigt

Status

Rekruttering

Betingelser

Intervention / Behandling

Undersøgelsestype

Interventionel

Tilmelding (Anslået)

6712

Fase

  • Fase 3

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiekontakt

Studiesteder

  • Argentina
      • Bahía Blanca, Argentina, B8000FTD
        • Rekruttering
        • Inst de Inv Clinicas-Bahia Blanca
        • Kontakt:
      • Buenos Aire, Argentina, C1425
        • Rekruttering
        • Swiss Medical Center Barrio Parque
        • Kontakt:
      • Buenos Aires, Argentina, 1425
        • Ikke rekrutterer endnu
        • CPSIC SRL - Cardiologia Palermo
        • Kontakt:
      • Ciudad Autonoma Buenos Aires, Argentina, C1428DCO
        • Rekruttering
        • Instituto Cardiovascular de Buenos Aires
        • Kontakt:
      • Ciudad Autonoma Buenos Aires, Argentina, C1015ABO
        • Ikke rekrutterer endnu
        • Organizacion Medica de Investigacion (OMI)
        • Kontakt:
      • Ciudad Autonoma Buenos Aires, Argentina, C1056ABJ
        • Rekruttering
        • Centro de Investigaciones Metabolicas (CINME)-Ciudad Autonoma Buenos Aires-41221
        • Kontakt:
      • Ciudad Autonoma Buenos Aires, Argentina, C1128AAF
        • Rekruttering
        • Mautalen- Salud e Investigacion
        • Kontakt:
      • Ciudad Autonoma Buenos Aires, Argentina, C1425AGC
      • Ciudad Autonoma Buenos Aires, Argentina, C1428ART
      • Ciudad Autonoma Buenos Aires, Argentina, C1430CKE
        • Rekruttering
        • Glenny Corp. S.A. Bioclinica Argentina
        • Kontakt:
      • Ciudad Autonoma de Bs As, Argentina, A1120AAC
      • Ciudad Autónoma de Bs As, Argentina, C1181ACH
        • Rekruttering
        • Hospital Italiano de Buenos Aires
        • Kontakt:
      • Ciudadela, Argentina, 1702
        • Rekruttering
        • Instituto Medico Elsa Perez SRL (IMEP)
        • Kontakt:
      • Coronel Suárez, Argentina, B7540GHD
      • Córdoba, Argentina, X5000JHQ
      • Córdoba, Argentina, X5002HWE
      • Córdoba, Argentina, X5003DCE
      • Córdoba, Argentina, X5002AOQ
        • Rekruttering
        • Sanatorio Privado Duarte Quiros De Clinica Colombo SA
        • Kontakt:
      • Córdoba, Argentina, X5006CBI
      • Mar del Plata, Argentina, B7600FYK
        • Rekruttering
        • Centro de Investigaciones Medicas Mar del Plata
        • Kontakt:
      • Mendoza, Argentina, 5500
        • Ikke rekrutterer endnu
        • Fundacion Scherbovsky
        • Kontakt:
      • Pilar, Argentina, B1629ODT
      • Quilmes, Argentina, B1878GEG
        • Rekruttering
        • Instituto de Investigaciones Clinicas de Quilmes
        • Kontakt:
      • Ramos Mejía, Argentina, 1704
      • Rosario, Argentina, S2000PBJ
      • Rosario, Argentina, 2000
        • Rekruttering
        • Instituto de Investigaciones Clinicas de Rosario
        • Kontakt:
      • Salta, Argentina, A4406BFP
      • San Martin, Argentina, B1650CSQ
        • Rekruttering
        • Corporacion Medica de Gral. San Martin S.A.
        • Kontakt:
      • San Miguel de Tucumán, Argentina, T4000ICL
        • Rekruttering
        • Investigaciones Clinicas Tucuman
        • Kontakt:
      • San Miguel de Tucumán, Argentina, T4000
      • San Miguel de Tucumán, Argentina, T4000
      • San Miguel de Tucumán, Argentina, T4000IAI
        • Rekruttering
        • Investigaciones en Patologias Respiratorias
        • Kontakt:
      • San Nicolás, Argentina, B2900DMH
        • Rekruttering
        • Instituto de Investigaciones Clinicas San Nicolas
        • Kontakt:
      • Santa Fe, Argentina, S3000FWO
        • Rekruttering
        • Centro de Investigaciones Clinicas del Litoral
        • Kontakt:
      • Villa Luro, Argentina, 1407
        • Rekruttering
        • CEMEDIC - Centro de Especialidades Medicas
        • Kontakt:
  • Australien
    • Australian Capital Territory
      • Garran, Australian Capital Territory, Australien, 2605
    • New South Wales
      • Concord, New South Wales, Australien, 2139
        • Rekruttering
        • Concord Repatriation General Hospital
        • Kontakt:
      • Gosford, New South Wales, Australien, 2250
      • Kingswood, New South Wales, Australien, 2747
      • Kotara, New South Wales, Australien, 2289
    • Queensland
      • Brisbane, Queensland, Australien, 4029
        • Ikke rekrutterer endnu
        • Royal Brisbane and Women's Hospital
        • Kontakt:
      • Chermside, Queensland, Australien, 4032
      • Tugun, Queensland, Australien, 4224
    • South Australia
      • Adelaide, South Australia, Australien, 5000
      • Woodville, South Australia, Australien, 5011
    • Victoria
      • Frankston, Victoria, Australien, 3199
      • Parkville, Victoria, Australien, 3050
    • Western Australia
      • Perth, Western Australia, Australien, 6000
  • Belgien
      • Genk, Belgien, 3600
      • Ghent, Belgien, 9000
      • Gilly, Belgien, 6060
      • Hasselt, Belgien, 3500
      • Kortrijk, Belgien, 8500
      • Leuven, Belgien, 3000
  • Brasilien
      • Aracaju, Brasilien, 49055-530
        • Rekruttering
        • Centro de Pesquisa Clínica do Coração
        • Kontakt:
      • Belo Horizonte, Brasilien, 30110-934
        • Rekruttering
        • Hospital Felicio Rocho
        • Kontakt:
      • Belo Horizonte, Brasilien, 30150-240
        • Rekruttering
        • Cardresearch Cardiologia Assistencial e de Pesquisas Ltda
        • Kontakt:
      • Belo Horizonte, Brasilien, 30140-092
      • Bragança Paulista, Brasilien, 1291-6542
        • Rekruttering
        • Hospital Universitário São Francisco na Providência de Deus
        • Kontakt:
      • Brasília, Brasilien, 70200-730
        • Rekruttering
        • L2IP -Instituto de Pesquisas Clínicas Ltda.
        • Kontakt:
      • Brasília, Brasilien, 70710-100
        • Rekruttering
        • CECAP - Centro de Cardiologia Clínica
        • Kontakt:
      • Brasília, Brasilien, 70390-140
      • Brasília, Brasilien, 71635-580
      • Brasília, Brasilien, 70390-903
        • Rekruttering
        • Hospital do Coracao do Brasil
        • Kontakt:
      • Campina Grande do Sul, Brasilien, 83430-000
        • Rekruttering
        • Hospital Angelina Caron
        • Kontakt:
      • Campinas, Brasilien, 13092-133
        • Rekruttering
        • Centro Especializado em Cardiol Loema Instituto de Pesq Clin
        • Kontakt:
      • Campinas, Brasilien, 13060-080
        • Rekruttering
        • IPECC - Instituto de Pesquisa Clínica de Campinas
        • Kontakt:
      • Campo Largo, Brasilien, 83606-177
      • Curitiba, Brasilien, 80230-130
        • Rekruttering
        • PUC Trials - Núcleo de Pesquisa Clínica da Escola de Medicina da PUC-PR
        • Kontakt:
      • Goiânia, Brasilien, 74223-130
      • Marília, Brasilien, 17515-000
        • Rekruttering
        • ICM - Instituto do Coracao de Marilia
        • Kontakt:
      • Natal, Brasilien, 59020-035
        • Rekruttering
        • Instituto Atena de Pesquisa Clinica
        • Kontakt:
      • Passo Fundo, Brasilien, 99010-120
        • Rekruttering
        • Instituto Mederi de Pesquisa e Saude
        • Kontakt:
      • Porto Alegre, Brasilien, 90430-001
        • Rekruttering
        • Universidade Federal do Rio Grande do Sul
        • Kontakt:
      • Porto Alegre, Brasilien, 90035-903
        • Rekruttering
        • Hospital de Clinicas de Porto Alegre
        • Kontakt:
      • Porto Alegre, Brasilien, 90840-440
        • Rekruttering
        • Centro Gaucho Integrado de Oncologia, Hematologia, Ensino e Pesquisa Sociedade Simples
        • Kontakt:
      • Porto Alegre, Brasilien, 90020-090
        • Rekruttering
        • Santa Casa de Misericordia de Porto Alegre
        • Kontakt:
      • Poços de Caldas, Brasilien, 37701-033
        • Ikke rekrutterer endnu
        • Hospital Maternidade e Pronto Socorro Santa Lucia
        • Kontakt:
      • Recife, Brasilien, 50070-480
        • Rekruttering
        • Hospital Esperança Recife
        • Kontakt:
      • Recife, Brasilien, 50720-110
        • Ikke rekrutterer endnu
        • Rede AME Saúde
        • Kontakt:
      • Ribeirão Preto, Brasilien, 14048-900
        • Rekruttering
        • Hospital das Clínicas FMRP-USP
        • Kontakt:
      • Ribeirão Preto, Brasilien, 14026-900
        • Rekruttering
        • Clinicor Clínica Cardiológica LTDA/ Cardio Prime - CAPED
        • Kontakt:
      • Rio Do Janeiro, Brasilien, 22270-060
        • Rekruttering
        • Ruschel Medicina e Pesquisa Clínica
        • Kontakt:
      • Rio de Janeiro, Brasilien, 20241-180
        • Rekruttering
        • Instituto Brasil de Pesquisa Clinica (IBPClin)
        • Kontakt:
      • Salvador, Brasilien, 40170-310
        • Rekruttering
        • Hospital Cardio Pulmonar
        • Kontakt:
      • Salvador, Brasilien, 40323-010
        • Ikke rekrutterer endnu
        • Hospital Ana Nery
        • Kontakt:
      • Santo André, Brasilien, 09080-110
      • Santo André, Brasilien, 09090-970
        • Rekruttering
        • Praxis Pesquisa Medica
        • Kontakt:
      • Sao Jose Rio Preto, Brasilien, 15090-000
        • Rekruttering
        • Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto
        • Kontakt:
      • São Luís, Brasilien, 65060-645
        • Ikke rekrutterer endnu
        • Hospital Sao Domingos
        • Kontakt:
      • São Paulo, Brasilien, 01228-200
        • Rekruttering
        • CPCLIN - Centro de Pesquisas Clínicas Ltda.
        • Kontakt:
      • São Paulo, Brasilien, 04266-010
        • Rekruttering
        • CEPIC - Centro Paulista de Investigacao Clinica e Servicos
        • Kontakt:
      • Uberlândia, Brasilien, 38411-186
        • Rekruttering
        • Eurolatino Pesquisas Médicas Ltda.
        • Kontakt:
      • Vitória, Brasilien, 29055-450
        • Rekruttering
        • CEDOES - Diagnóstico e Pesquisa,Vitória
        • Kontakt:
      • Votuporanga, Brasilien, 15501-405
        • Rekruttering
        • Integral Pesquisa e Ensino
        • Kontakt:
  • Bulgarien
      • Burgas, Bulgarien, 8008
        • Rekruttering
        • Medical Center Doktor Staykov Ltd.
        • Kontakt:
      • Burgas, Bulgarien, 8000
        • Ikke rekrutterer endnu
        • Medical center 4LIFE Ltd.
        • Kontakt:
      • Dimitrovgrad, Bulgarien, 6400
      • Gotse Delchev, Bulgarien, 2900
      • Kardzhali, Bulgarien, 6600
      • Kyustendil, Bulgarien, 2500
        • Rekruttering
        • Medical Center Hera - Kyustendil EOOD
        • Kontakt:
      • Pernik, Bulgarien, 2300
        • Rekruttering
        • Ambulatory Individual Practice for Cardiology Specialized Medical Care
        • Kontakt:
      • Pleven, Bulgarien, 5803
        • Rekruttering
        • Ambulatory for Individual Practice for Specialized Medical Care in Cardiology - Dr Nikolay Iliev
        • Kontakt:
      • Pleven, Bulgarien, 5800
        • Rekruttering
        • Medical Center Medconsult Pleven OOD
        • Kontakt:
      • Pleven, Bulgarien, 5800
      • Plovdiv, Bulgarien, 4002
      • Rousse, Bulgarien, 7013
      • Sofia, Bulgarien, 1510
      • Sofia, Bulgarien, 1606
        • Rekruttering
        • Multiprofile Hospital MHATEM 'Pirogov', Sofia
        • Kontakt:
      • Sofia, Bulgarien, 1527
      • Sofia, Bulgarien, 1680
      • Sofia, Bulgarien, 1431
        • Rekruttering
        • Diagnostic Consultative Center Alexandrovska
        • Kontakt:
      • Sofia, Bulgarien, 1431
        • Rekruttering
        • University Multidisciplinary Hospital for Active Treatment Sveta Ekaterina EAD
        • Kontakt:
      • Sofia, Bulgarien, 1680
      • Sofia, Bulgarien, 1618
        • Rekruttering
        • Diagnostic Consultation Center XX-Sofia EOOD
        • Kontakt:
      • Sofia, Bulgarien, 1756
      • Sofia, Bulgarien, 1431
        • Rekruttering
        • Alexandrovska University Hospital
        • Kontakt:
      • Sofia, Bulgarien, 1618
      • Sofia, Bulgarien, 1582
        • Rekruttering
        • ASOMHIDC - Individual practice "Cardio Tonus" EOOD
        • Kontakt:
      • Sofia, Bulgarien, 1309
        • Rekruttering
        • Medical Center For Specialized Medical Help In Cardiovascular Diseases OOD
        • Kontakt:
      • Sofia, Bulgarien, 1233
        • Rekruttering
        • National Multiprofile Transport Hospital "Tzar Boris III"
        • Kontakt:
      • Stara Zagora, Bulgarien, 6000
        • Rekruttering
        • UMHAT Prof. Dr. Stoyan Kirkovich AD
        • Kontakt:
      • Stara Zagora, Bulgarien, 6010
      • Varna, Bulgarien, 9000
        • Rekruttering
        • Diagnostichno-Consultativen Center Chaika EOOD
        • Kontakt:
      • Veliko Tarnovo, Bulgarien, 5006
      • Yambol, Bulgarien, 8600
      • Yambol, Bulgarien, 8600
        • Afsluttet
        • MHAT St Panteleimon
  • Canada
      • Edmonton, Canada, T5H 3V9
        • Rekruttering
        • Royal Alexandra Hospital (Edmonton)
        • Kontakt:
      • Greater Sudbury, Canada, P3E 5J1
        • Rekruttering
        • Health Sciences North
        • Kontakt:
      • Kitchener, Canada, N2H5Z8
        • Ikke rekrutterer endnu
        • Clinical Research Solutions Inc. (Kitchener)
        • Kontakt:
      • Montreal, Canada, H3G 1A4
        • Rekruttering
        • Montreal General Hospital - McGill University Health Centre
        • Kontakt:
      • Montreal, Canada, H2X 0C1
        • Rekruttering
        • Centre Hospitalier de l'Universite de Montreal (CHUM)
        • Kontakt:
      • Saint-Jean-sur-Richelieu, Canada, J3A 1J2
    • Ontario
      • Cambridge, Ontario, Canada, N1R 6V6
        • Rekruttering
        • Cambridge Cardiac Care Centre
        • Kontakt:
      • Hamilton, Ontario, Canada, L8L 0A9
        • Rekruttering
        • Curnew Medicine Professional Corporation
        • Kontakt:
      • Mississauga, Ontario, Canada, L5K 2L3
        • Rekruttering
        • KMH Cardiology Centres (Mississauga)
        • Kontakt:
      • Oakville, Ontario, Canada, L6M 0L8
        • Rekruttering
        • Oakville Trafalgar Memorial Hospital
        • Kontakt:
      • Oshawa, Ontario, Canada, L1J 2K1
      • Peterborough, Ontario, Canada, K9J 0B2
        • Rekruttering
        • Kawartha Cardiology Clinical Trials
        • Kontakt:
      • Sarnia, Ontario, Canada, N7T 4P5
        • Rekruttering
        • CardioQuest Research Centre
        • Kontakt:
      • Stoney Creek, Ontario, Canada, L8J 3W2
        • Rekruttering
        • KMH Cardiology Centres (Hamilton)
        • Kontakt:
      • Toronto, Ontario, Canada, M6G 1M2
        • Rekruttering
        • Diabetes Heart Research Centre
        • Kontakt:
    • Quebec
      • Greenfield Park, Quebec, Canada, J4V 2G8
        • Rekruttering
        • ViaCar Recherches Cliniques Inc. (Greenfield Park)
        • Kontakt:
      • Montreal, Quebec, Canada, H3T 1E2
        • Rekruttering
        • Jewish General Hospital
        • Kontakt:
      • Trois-Rivières, Quebec, Canada, G9A 4P3
        • Rekruttering
        • Diex Recherche (Trois-Rivieres)
        • Kontakt:
  • Chile
      • Puerto Varas, Chile, 5550170
        • Rekruttering
        • Quantum Research Santiago, Puerto Varas
        • Kontakt:
      • Santiago, Chile, 8900000
        • Rekruttering
        • Sociedad Medica Cardiologica El Llano
        • Kontakt:
      • Talcahuano, Chile, 4270918
        • Rekruttering
        • Hospital Las Higueras
        • Kontakt:
      • Temuco, Chile, 4780000
      • Viña del Mar, Chile, 2570017
        • Rekruttering
        • CINVEC - Centro de Investigacion Clinica V Reg.,Vina del Mar
        • Kontakt:
  • Colombia
      • Armenia, Colombia, 630004
      • Barranquilla, Colombia, 80020
        • Rekruttering
        • Centro de Investigacion Medico Asistencial S.A.S
        • Kontakt:
      • Barranquilla, Colombia, 080020
        • Rekruttering
        • IPS Centro Cientifico-Asistencial S.A.S
        • Kontakt:
      • Barranquilla, Colombia, 74158
      • Cali, Colombia, 760001
        • Rekruttering
        • IPS Centro Medico Julian Coronel S.A.
        • Kontakt:
      • Cartagena, Colombia, 130001
        • Rekruttering
        • Centro De Diagnostico Cardiologico Ltda
        • Kontakt:
      • Floridablanca, Colombia, 6810002
        • Rekruttering
        • Fundacion Cardiovascular de Colombia
        • Kontakt:
      • Manizales, Colombia, 170004
        • Rekruttering
        • Asociacion IPS medicos internistas de Caldas S.A.S.
        • Kontakt:
      • Medellín, Colombia, 05001
        • Rekruttering
        • Fundacion Centro de Investigacion Clinica CIC
        • Kontakt:
      • Pereira, Colombia, 66001
      • Santa Marta, Colombia, 470001
        • Rekruttering
        • T Y C Inversiones S.A.S Grupsalud
        • Kontakt:
      • Zipaquirá, Colombia, 250252
        • Rekruttering
        • Healthy Medical Center S.A.S
        • Kontakt:
  • Det Forenede Kongerige
      • Barnet, Det Forenede Kongerige, EN5 3DJ
      • Bristol, Det Forenede Kongerige, BS10 5NB
      • Exeter, Det Forenede Kongerige, EX2 5DW
      • Halifax, Det Forenede Kongerige, HX3 0PW
      • High Wycombe, Det Forenede Kongerige, HP11 2TT
      • London, Det Forenede Kongerige, EC1A 7BE
      • Oldham, Det Forenede Kongerige, OL1 2JH
      • Sheffield, Det Forenede Kongerige, S5 7AU
      • Truro, Det Forenede Kongerige, TR1 3LJ
      • York, Det Forenede Kongerige, YO31 8HE
  • Forenede Stater
    • Alabama
      • Mobile, Alabama, Forenede Stater, 36608
      • Mobile, Alabama, Forenede Stater, 36604
    • California
      • Chula Vista, California, Forenede Stater, 91911
      • Orange, California, Forenede Stater, 92868
      • San Dimas, California, Forenede Stater, 91773
      • Santa Clarita, California, Forenede Stater, 91355
      • Tustin, California, Forenede Stater, 92780
    • Connecticut
      • Bridgeport, Connecticut, Forenede Stater, 06610
    • Florida
      • Boca Raton, Florida, Forenede Stater, 33434
      • Brandon, Florida, Forenede Stater, 33511
      • Clearwater, Florida, Forenede Stater, 33756
        • Rekruttering
        • Clearwater Cardiovascular and Interventional Consultants
        • Kontakt:
      • Daytona Beach, Florida, Forenede Stater, 32117
      • Gainesville, Florida, Forenede Stater, 32608
      • Hallandale, Florida, Forenede Stater, 33009
        • Rekruttering
        • Velocity Clinical Research-Hallandale Beach-67888
        • Kontakt:
      • Jacksonville, Florida, Forenede Stater, 32256
      • Jacksonville, Florida, Forenede Stater, 32209
      • Jacksonville, Florida, Forenede Stater, 32216
        • Rekruttering
        • East Coast Institute for Research, LLC - Jacksonville
        • Kontakt:
      • Largo, Florida, Forenede Stater, 33777
        • Rekruttering
        • Clearwater Cardiovascular Consultants-Largo-69917
        • Kontakt:
      • Miami, Florida, Forenede Stater, 33136
      • Miramar Beach, Florida, Forenede Stater, 32550
      • Naples, Florida, Forenede Stater, 34102
        • Ikke rekrutterer endnu
        • Advanced Research for Health Improvement, LLC
        • Kontakt:
      • Naples, Florida, Forenede Stater, 34102
      • Ocala, Florida, Forenede Stater, 34471
      • Ocala, Florida, Forenede Stater, 34471
      • Port Charlotte, Florida, Forenede Stater, 33952
      • Saint Augustine, Florida, Forenede Stater, 32086
        • Rekruttering
        • East Coast Institute for Research, LLC-Saint Augustine-63032
        • Kontakt:
      • Tampa, Florida, Forenede Stater, 33612
      • Wellington, Florida, Forenede Stater, 33449
        • Rekruttering
        • Cardiology Partners Clinical Research Institute
        • Kontakt:
      • Wesley Chapel, Florida, Forenede Stater, 33544
      • Winter Park, Florida, Forenede Stater, 32789
    • Georgia
      • Atlanta, Georgia, Forenede Stater, 30342
      • Columbus, Georgia, Forenede Stater, 31904
      • Johns Creek, Georgia, Forenede Stater, 30024
    • Idaho
      • Coeur d'Alene, Idaho, Forenede Stater, 83814
    • Illinois
      • Arlington Heights, Illinois, Forenede Stater, 60005
      • Chicago, Illinois, Forenede Stater, 60657
      • Hazel Crest, Illinois, Forenede Stater, 60429
      • Libertyville, Illinois, Forenede Stater, 60048
        • Rekruttering
        • Clinical Investigation Specialists, Inc.-Libertyville-69941
        • Kontakt:
      • Park Ridge, Illinois, Forenede Stater, 60068
    • Indiana
      • Elkhart, Indiana, Forenede Stater, 46514
        • Rekruttering
        • Midwest Cardiovascular Research and Education Foundation
        • Kontakt:
      • Indianapolis, Indiana, Forenede Stater, 46237
        • Rekruttering
        • St. Francis Medical Group-Indiana Heart Physicians, Inc
        • Kontakt:
      • Merrillville, Indiana, Forenede Stater, 46410
      • Munster, Indiana, Forenede Stater, 46321
        • Rekruttering
        • Cardiovascular Research of Northwest Indiana, LLC
        • Kontakt:
      • Richmond, Indiana, Forenede Stater, 47374
    • Iowa
      • West Des Moines, Iowa, Forenede Stater, 50266
    • Kansas
      • Wichita, Kansas, Forenede Stater, 67226
        • Rekruttering
        • West Houston Area Clinical Trial Consultants, LLC - Wichita
        • Kontakt:
    • Kentucky
      • Louisville, Kentucky, Forenede Stater, 40205
    • Louisiana
      • Bossier City, Louisiana, Forenede Stater, 71111
      • Hammond, Louisiana, Forenede Stater, 70403
      • Shreveport, Louisiana, Forenede Stater, 71105
      • Slidell, Louisiana, Forenede Stater, 70458
    • Maryland
      • Baltimore, Maryland, Forenede Stater, 21229
    • Michigan
      • Dearborn, Michigan, Forenede Stater, 48126
      • Lansing, Michigan, Forenede Stater, 48910-0826
      • Southfield, Michigan, Forenede Stater, 48075
      • Ypsilanti, Michigan, Forenede Stater, 48197
        • Rekruttering
        • Trinity Health Michigan D/B/A Michigan Heart
        • Kontakt:
    • Minnesota
      • Minneapolis, Minnesota, Forenede Stater, 55417
    • Mississippi
      • Jackson, Mississippi, Forenede Stater, 39216
    • Missouri
      • Kansas City, Missouri, Forenede Stater, 64128
      • North Kansas City, Missouri, Forenede Stater, 64116
      • St Louis, Missouri, Forenede Stater, 63136
    • Nebraska
      • Lincoln, Nebraska, Forenede Stater, 68506
    • New Jersey
      • Bridgewater, New Jersey, Forenede Stater, 08807
      • Manalapan, New Jersey, Forenede Stater, 07726
      • Somerset, New Jersey, Forenede Stater, 08873
    • New York
      • New York, New York, Forenede Stater, 10029
      • New York, New York, Forenede Stater, 10001
      • The Bronx, New York, Forenede Stater, 10469
    • North Carolina
      • Greensboro, North Carolina, Forenede Stater, 27405
      • Raleigh, North Carolina, Forenede Stater, 27610
    • Ohio
      • Marion, Ohio, Forenede Stater, 43302
      • Toledo, Ohio, Forenede Stater, 43608
    • South Carolina
      • Greenville, South Carolina, Forenede Stater, 29607
        • Rekruttering
        • Bon Secours Medical Group Greenville Specialty Care, LLC
        • Kontakt:
    • South Dakota
      • Rapid City, South Dakota, Forenede Stater, 57701
    • Tennessee
      • Jackson, Tennessee, Forenede Stater, 38305
      • Jefferson City, Tennessee, Forenede Stater, 37760
    • Texas
      • Amarillo, Texas, Forenede Stater, 79124
        • Rekruttering
        • Amarillo Heart Clinical Research Institute, Incorporated
        • Kontakt:
      • Amarillo, Texas, Forenede Stater, 79109
      • Dallas, Texas, Forenede Stater, 75390
        • Rekruttering
        • University of Texas Southwestern Medical Center
        • Kontakt:
      • Dallas, Texas, Forenede Stater, 75235
      • Dallas, Texas, Forenede Stater, 75231
        • Rekruttering
        • Texas Health Research and Education Institute
        • Kontakt:
      • Fort Worth, Texas, Forenede Stater, 76104
      • Katy, Texas, Forenede Stater, 77493
        • Rekruttering
        • West Houston Area Clinical Trial Consultants, LLC - Katy
        • Kontakt:
      • Kingwood, Texas, Forenede Stater, 77339
      • Longview, Texas, Forenede Stater, 75605
      • McKinney, Texas, Forenede Stater, 75071
      • McKinney, Texas, Forenede Stater, 75071
    • Utah
      • Salt Lake City, Utah, Forenede Stater, 84108
    • Virginia
      • Manassas, Virginia, Forenede Stater, 20109
      • Norfolk, Virginia, Forenede Stater, 23507
      • Winchester, Virginia, Forenede Stater, 22601
    • Washington
      • Seattle, Washington, Forenede Stater, 98101
    • Wisconsin
      • Madison, Wisconsin, Forenede Stater, 53717
      • Waukesha, Wisconsin, Forenede Stater, 53188
        • Rekruttering
        • ProHealth Care Research Institute and Cardiology Associates
        • Kontakt:
  • Holland
      • 's-Hertogenbosch, Holland, 5223 GZ
        • Rekruttering
        • Jeroen Bosch Ziekenhuis-Hertogenbosch
        • Kontakt:
      • Arnhem, Holland, 6815 AD
      • Breda, Holland, 4818 CK
      • Deventer, Holland, 7416 SE
      • Eindhoven, Holland, 5623 EJ
      • Gouda, Holland, 2803 HH
      • Leiderdorp, Holland, 2353 GA
      • Nieuwegein, Holland, 3435 CM
      • Rotterdam, Holland, 3083 AN
      • Zaandam, Holland, 1502 DV
        • Rekruttering
        • De Heel - Zaans Medisch Centrum
        • Kontakt:
  • Indien
      • Bangalore, Indien, 560099
        • Rekruttering
        • Narayana Institute of Cardiac Sciences
        • Kontakt:
      • Bengaluru, Indien, 560002
        • Rekruttering
        • Bangalore Medical college
        • Kontakt:
      • Bikaner, Indien, 334003
        • Rekruttering
        • S.P. Medical College & Associated Group of Hospitals
        • Kontakt:
      • Chennai, Indien, 600002
        • Rekruttering
        • Tamil Nadu Government Multi Super Speciality Hospital TNGMSSH
        • Kontakt:
      • Chennai, Indien, 600006
        • Rekruttering
        • Apollo Main Hospital
        • Kontakt:
      • Chhatrapati Sambhajinagar, Indien, 431 005
        • Rekruttering
        • Kamalnayan Bajaj Hospital
        • Kontakt:
      • Guwahati, Indien, 781006
        • Ikke rekrutterer endnu
        • GNRC Hospital
        • Kontakt:
      • Gūrgaon, Indien, 122 001
        • Ikke rekrutterer endnu
        • Medanta-The Medicity
        • Kontakt:
      • Kochi, Indien, 682 018
        • Rekruttering
        • Lisie Hospital
        • Kontakt:
      • Kolkata, Indien, 700020
        • Rekruttering
        • IPGMER and SSKM Hospital
        • Kontakt:
      • Nashik, Indien, 422005
        • Rekruttering
        • Chopda Medicare and Research Centre Pvt Ltd
        • Kontakt:
      • New Delhi, Indien, 110017
        • Rekruttering
        • Max Super Speciality Hospital
        • Kontakt:
      • Surat, Indien, 395002
        • Rekruttering
        • Unicare Heart Institute
        • Kontakt:
      • Visakhapatnam, Indien, 530002
        • Rekruttering
        • King George Hospital
        • Kontakt:
  • Italien
      • Bergamo, Italien, 24125
      • Bergamo, Italien, 24127
        • Rekruttering
        • ASST Papa Giovanni XXIII
        • Kontakt:
      • Foggia, Italien, 71122
        • Rekruttering
        • Az.Osp. Universitaria "Ospedali Riuniti"
        • Kontakt:
      • Genova, Italien, 16132
        • Rekruttering
        • Azienda Ospedaliera San Martino
        • Kontakt:
      • Naples, Italien, 80131
        • Rekruttering
        • Azienda Ospedaliera Universitaria "Federico II"
        • Kontakt:
      • Pavia, Italien, 27100
        • Rekruttering
        • Fondazione IRCCS Policlinico S. Matteo
        • Kontakt:
      • Roma, Italien, 00189
        • Rekruttering
        • Azienda Ospedaliera Sant'Andrea-Università di Roma La Sapienza
        • Kontakt:
      • Rozzano, Italien, 20089
        • Rekruttering
        • Istituto Clinico Humanitas
        • Kontakt:
  • Japan
      • Aichi, Kasugai, Japan, 486-8510
        • Rekruttering
        • Kasugai Municipal Hospital
        • Kontakt:
      • Azumino-shi, Japan, 399-8292
        • Rekruttering
        • Azumino Red Cross Hospital
        • Kontakt:
      • Chiba, Chiba, Japan, 263-0043
      • Chūōku, Japan, 103-0027
        • Rekruttering
        • Tokyo-Eki Center-building Clinic
        • Kontakt:
      • Fujisawa-shi, Japan, 251-0041
        • Rekruttering
        • Shonan Fujisawa Tokushukai Hospital
        • Kontakt:
      • Fukuoka, Kitakyushu, Japan, 802-8555
        • Ikke rekrutterer endnu
        • Kokura Memorial Hospital
        • Kontakt:
      • Hachioji-shi, Japan, 192-0918
        • Ikke rekrutterer endnu
        • Minamino Cardiovascular Hospital
        • Kontakt:
      • Hamada-shi, Japan, 697-8511
        • Rekruttering
        • National Hospital Organization Hamada Medical Center
        • Kontakt:
      • Higashiibaraki-gun, Japan, 311-3193
        • Rekruttering
        • NHO Mito Medical Center
        • Kontakt:
      • Himeji-shi, Japan, 670-8560
        • Rekruttering
        • Hyogo Prefectural Harima-Himeji General Medical Center
        • Kontakt:
      • Hiratsuka-shi, Japan, 254-8502
        • Rekruttering
        • Hiratsuka Kyosai Hospital
        • Kontakt:
      • Hokkaido, Sapporo, Japan, 003-0026
        • Rekruttering
        • Matsuda Cardiovascular Clinic
        • Kontakt:
      • Hokkaido, Tomakomai, Japan, 053-8506
        • Rekruttering
        • Oji General Hospital
        • Kontakt:
      • Hyogo, Amagasaki, Japan, 660-8550
        • Rekruttering
        • Hyogo Prefectural Amagasaki General Medical Center
        • Kontakt:
      • Ikeda-cho, Kitaazumi, Japan, 399-8695
        • Rekruttering
        • North Alps Medical Center Azumi Hospital
        • Kontakt:
      • Ishikawa, Kanazawa, Japan, 920-8650
        • Rekruttering
        • National Hospital Organization Kanazawa Medical Center
        • Kontakt:
      • Iwakuni-shi, Japan, 740-8510
        • Rekruttering
        • National Hospital Organization Iwakuni Clinical Center
        • Kontakt:
      • Kamakura-shi, Japan, 247-8533
        • Rekruttering
        • Tokushukai Shonan Kamakura General Hospital
        • Kontakt:
      • Kanagawa, Miura-gun, Japan, 240-0116
        • Rekruttering
        • Tokushukai Hayama Heart Center
        • Kontakt:
      • Kanagawa, Yokohama, Japan, 236-0051
        • Rekruttering
        • Kanagawa Cardiovascular and Respiratory Center
        • Kontakt:
      • Kanagawa, Yokohama, Japan, 247-8581
        • Rekruttering
        • Yokohama Sakae Kyosai Hospital
        • Kontakt:
      • Kanonji-shi, Japan, 769-1695
        • Rekruttering
        • Mitoyo General Hospital
        • Kontakt:
      • Kawanishi-shi, Japan, 666-0125
        • Ikke rekrutterer endnu
        • The Veritas Hospital
        • Kontakt:
      • Kishiwada-shi, Japan, 596-0042
        • Rekruttering
        • Tokushukai Kishiwada Tokushukai Hospital
        • Kontakt:
      • Kobe, Japan, 654-0155
        • Rekruttering
        • National Hospital Organization Kobe Medical Center
        • Kontakt:
      • Kumamoto, Japan, 861-8520
        • Rekruttering
        • Japanese Red Cross Kumamoto Hospital
        • Kontakt:
      • Matsumoto-shi, Japan, 390-8621
        • Rekruttering
        • Shinshu University Hospital
        • Kontakt:
      • Matsuyama, Japan, 790-0024
        • Rekruttering
        • Ehime Prefectural Central Hospital
        • Kontakt:
      • Matsuyama, Japan, 790-0067
        • Rekruttering
        • Matsuyama Shimin Hospital
        • Kontakt:
      • Mito, Japan, 311-4198
        • Rekruttering
        • Mito Saiseikai General Hospital
        • Kontakt:
      • Nakano-shi, Japan, 383-8505
        • Rekruttering
        • Hokushin General Hospital
        • Kontakt:
      • Okayama, Okayama, Japan, 700-8557
        • Rekruttering
        • Okayama City General Medical Center Okayama City Hospital
        • Kontakt:
      • Okinawa, Naha, Japan, 902-8511
      • Okinawa, Urasoe, Japan, 901-2102
        • Rekruttering
        • Urasoe General Hospital
        • Kontakt:
      • Osaka, Japan, 547-0011
        • Ikke rekrutterer endnu
        • Ikebuchi Clinic
        • Kontakt:
      • Osaka, Osaka, Japan, 530-8480
      • Osaka, Osaka, Japan, 543-8922
        • Rekruttering
        • Osaka Keisatsu Hospital
        • Kontakt:
      • Osaka, Osaka, Japan, 550-0006
        • Rekruttering
        • Nippon Life Hospital
        • Kontakt:
      • Osaka, Osaka, Japan, 553-0003
        • Rekruttering
        • Japan Community Health care Organization Osaka Hospital
        • Kontakt:
      • Osaka, Osaka, Japan, 558-8558
        • Rekruttering
        • Osaka General Medical Center
        • Kontakt:
      • Saga, Japan, 840-8571
        • Rekruttering
        • Saga-Ken Medical Centre Koseikan
        • Kontakt:
      • Saitama-shi, Japan, 331-8577
        • Rekruttering
        • Sainokuni Higashiomiya Medical Center
        • Kontakt:
      • Saitama-shi, Japan, 338-0837
      • Sendai, Japan, 983-8520
        • Rekruttering
        • NHO Sendai Medical Center
        • Kontakt:
      • Suita-shi, Japan, 565-0871
        • Rekruttering
        • The University of Osaka Hospital
        • Kontakt:
      • Tachikawa-shi, Japan, 190-8531
      • Takamatsu, Japan, 760-8557
        • Rekruttering
        • Kagawa Prefectural Central Hospital
        • Kontakt:
      • Tokushima, Japan, 770-8539
        • Rekruttering
        • Tokushima Prefectural Central Hospital
        • Kontakt:
      • Tokyo, Ome, Japan, 198-0042
        • Rekruttering
        • Ome Municipal General Hospital
        • Kontakt:
      • Tomakomai-shi, Japan, 053-8567
        • Rekruttering
        • Tomakomai City Hospital
        • Kontakt:
      • Ōita, Japan, 870-0263
        • Rekruttering
        • NHO Oita Medical Center
        • Kontakt:
  • Kina
      • Baotou, Kina, 014040
        • Rekruttering
        • Baotou Central Hospital
        • Kontakt:
      • Baotou, Kina, 014010
        • Rekruttering
        • The First Affiliated Hospital of Baotou Medical College
        • Kontakt:
      • Beijing, Kina, 100191
        • Rekruttering
        • Peking University Third Hospital
        • Kontakt:
      • Beijing, Kina, 100029
        • Rekruttering
        • Beijing AnZhen Hospital, Capital Medical University
        • Kontakt:
      • Beijing, Kina, 100037
        • Rekruttering
        • Cardiovascular Institute and Fu Wai Hospital
        • Kontakt:
      • Changchun, Kina, 130021
        • Rekruttering
        • The First Hospital of Jilin University
        • Kontakt:
      • Changchun, Kina, 130033
        • Rekruttering
        • China-Japan Union Hospital of Jilin University
        • Kontakt:
      • Changchun, Kina, 130021
        • Rekruttering
        • Jilin Province People's Hospital
        • Kontakt:
      • Changde, Kina, 415001
        • Rekruttering
        • Changde Second People's Hospital
        • Kontakt:
      • Changsha, Kina, 410015
        • Rekruttering
        • The Third Hospital of Changsha
        • Kontakt:
      • Changsha, Kina, 410004
        • Rekruttering
        • Changsha Central Hospital
        • Kontakt:
      • Changsha, Kina, 410011
        • Rekruttering
        • The Second Xiangya Hospital Of Central South University
        • Kontakt:
      • Changsha, Kina, 410013
        • Rekruttering
        • The third xiangya hospital of Central South University
        • Kontakt:
      • Chengdu, Kina, 610041
        • Rekruttering
        • West China Hospital, Sichuan University
        • Kontakt:
      • Chengdu, Kina, 610500
        • Rekruttering
        • The First Affiliated Hospital of Chengdu Medical College
        • Kontakt:
      • Chengdu, Kina, 610021
        • Rekruttering
        • Chengdu Second People's Hospital
        • Kontakt:
      • Chenzhou, Kina, 423000
        • Rekruttering
        • Chenzhou No.1 people's Hospital
        • Kontakt:
      • Dalian, Kina, 116001
        • Rekruttering
        • Affiliated Zhongshan Hospital of Dalian University
        • Kontakt:
      • Daqing, Kina, 163001
        • Rekruttering
        • Daqing Oilfield General Hospital
        • Kontakt:
      • Daqing, Kina, 163711
        • Rekruttering
        • Daqingshi People's Hospital
        • Kontakt:
      • Deyang, Kina, 618099
        • Rekruttering
        • Deyang People's Hospital
        • Kontakt:
      • Foshan, Kina, 528000
        • Rekruttering
        • The First People's Hospital of Foshan
        • Kontakt:
      • Fuzhou, Kina, 350005
        • Rekruttering
        • The First Affiliated Hospital of Fujian Medical University
        • Kontakt:
      • Fuzhou, Kina, 350025
        • Ikke rekrutterer endnu
        • No.900 Hospital of PLA Joint Logistics Support Force
        • Kontakt:
      • Guangzhou, Kina, 510080
        • Rekruttering
        • Guangdong Provincial People's Hospital
        • Kontakt:
      • Guangzhou, Kina, 510150
        • Rekruttering
        • Third Affiliated Hospital of Guangzhou Medical University
        • Kontakt:
      • Guangzhou, Kina, 511400
        • Rekruttering
        • The Affiliated Panyu Central Hospital of Guangzhou Medical University
        • Kontakt:
      • Guangzhou, Kina, 510120
        • Rekruttering
        • Sun yet-sen Memorial Hospital, Sun yet-sen Univesity
        • Kontakt:
      • Guangzhou, Kina, 510400
        • Rekruttering
        • The First Affiliated Hospital of Guangzhou University of Chinese Medicine
        • Kontakt:
      • Guiyang, Kina, 550000
        • Rekruttering
        • The Affiliated Hospital of Guizhou Medical University
        • Kontakt:
      • Guiyang, Kina, 550002
        • Rekruttering
        • Guizhou Provincial People's Hospital
        • Kontakt:
      • Haikou, Kina, 570311
        • Rekruttering
        • Hainan General Hospital
        • Kontakt:
      • Hangzhou, Kina, 311199
        • Rekruttering
        • Hangzhou First People's Hospital
        • Kontakt:
      • Harbin, Kina, 150040
        • Rekruttering
        • The First Affiliated Hospital of Harbin Medical University
        • Kontakt:
      • Huainan, Kina, 232007
        • Rekruttering
        • Huainan First People's Hospital
        • Kontakt:
      • Jiangmen, Kina, 529030
        • Rekruttering
        • Jiangmen Central Hospital
        • Kontakt:
      • Jinan, Kina, 250013
        • Rekruttering
        • Center Hospital of Jinan
        • Kontakt:
      • Jining, Kina, 272011
        • Rekruttering
        • Jining No.1 People's Hospital
        • Kontakt:
      • Lanzhou, Kina, 730030
        • Rekruttering
        • Lanzhou University Second Hospital
        • Kontakt:
      • Linfen, Kina, 041000
        • Rekruttering
        • Linfen Central Hospital
        • Kontakt:
      • Luoyang, Kina, 471002
        • Rekruttering
        • Luoyang Third People's Hospital
        • Kontakt:
      • Luoyang, Kina, 471000
        • Rekruttering
        • The First Affiliated Hospital of Henan University of Science and Technology
        • Kontakt:
      • Nanchang, Kina, 330006
        • Rekruttering
        • The First Affiliated Hospital of Nanchang University
        • Kontakt:
      • Nanchang, Kina, 330003
        • Rekruttering
        • Jiangxi Province Integrated Tractional Chinese Medicine& Western Medicine Hospital
        • Kontakt:
      • Nanchang, Kina, 330009
        • Rekruttering
        • Nanchang People's Hospital
        • Kontakt:
      • Nanjing, Kina, 210008
        • Rekruttering
        • Nanjing Drum Tower Hospital
        • Kontakt:
      • Nanjing, Kina, 211100
        • Rekruttering
        • Nanjing Jiangning Hospital
        • Kontakt:
      • Nanning, Kina, 530021
        • Rekruttering
        • The First Affiliated Hospital of Guangxi Medical University
        • Kontakt:
      • Nanyang, Kina, 473009
        • Rekruttering
        • Nanyang Second General Hospital
        • Kontakt:
      • Nanyang, Kina, 473004
        • Rekruttering
        • Nanyang First People's Hospital
        • Kontakt:
      • Panjin, Kina, 124010
        • Rekruttering
        • Panjin Liao Oil Gem Flower Hospital
        • Kontakt:
      • Pingxiang, Kina, 337055
        • Rekruttering
        • Pingxiang People's Hospital
        • Kontakt:
      • Shanghai, Kina, 200080
        • Rekruttering
        • Shanghai General Hospital
        • Kontakt:
      • Shanghai, Kina, 200032
        • Rekruttering
        • Zhongshan Hospital Affiliated to Fudan University
        • Kontakt:
      • Shanghai, Kina, 200050
        • Rekruttering
        • Tongren hospital, Shanghai Jiaotong University School of Medicine
        • Kontakt:
      • Shengyang, Kina, 110004
        • Rekruttering
        • Shengjing Hospital of China Medical University
        • Kontakt:
      • Shenzhen, Kina, 518172
        • Rekruttering
        • Shenzhen People's Hospital
        • Kontakt:
      • Shijiazhuang, Kina, 050000
        • Rekruttering
        • The Second Hospital of Hebei Medical University
        • Kontakt:
      • Tianjin, Kina, 300121
        • Rekruttering
        • Tianjin Union Medical Center Nankai University Affiliated Hospital
        • Kontakt:
      • Wenzhou, Kina, 325000
        • Rekruttering
        • Wenzhou People's Hospital
        • Kontakt:
      • Wuhan, Kina, 430060
        • Rekruttering
        • Renmin Hospital of Wuhan University
        • Kontakt:
      • Wuhan, Kina, 430032
        • Rekruttering
        • Hubei Province Zhongshan Hospital
        • Kontakt:
      • Wuhan, Kina, 430033
        • Rekruttering
        • Wuhan Puai Hospital
        • Kontakt:
      • Xi'an, Kina, 710068
        • Rekruttering
        • Shaanxi Provincial People's Hospital
        • Kontakt:
      • Xiangtan, Kina, 411100
        • Rekruttering
        • Xiangtan Central Hospital
        • Kontakt:
      • Xinxiang, Kina, 453003
        • Rekruttering
        • The Third Affiliated Hospital of Xinxiang Medical University
        • Kontakt:
      • Xuancheng, Kina, 242000
        • Rekruttering
        • The People's Hospital Of Xuancheng City
        • Kontakt:
      • Xuzhou, Kina, 221006
        • Rekruttering
        • The General Hospital of XZCMG (The Second Affiliated Hospital of Xuzhou Medical University)
        • Kontakt:
      • Yanji, Kina, 133000
        • Rekruttering
        • Yanbian University Hospital
        • Kontakt:
      • Yinchuan, Kina, 750001
        • Rekruttering
        • The first People's Hosptal of Yinchuan
        • Kontakt:
      • Yueyang, Kina, 414000
        • Rekruttering
        • Yueyang Central Hospital
        • Kontakt:
      • Yuncheng, Kina, 44000
        • Rekruttering
        • Yuncheng Central Hospital
        • Kontakt:
      • Zhangjiakou, Kina, 075000
        • Rekruttering
        • The First Affiliated Hospital of Hebei North University
        • Kontakt:
      • Zhengzhou, Kina, 450052
        • Rekruttering
        • The First Affiliated Hospital of Zhengzhou University
        • Kontakt:
      • Zhenjiang, Kina, 212001
        • Rekruttering
        • Affiliated Hospital of Jiangsu University
        • Kontakt:
  • Mexico
      • Aguascalientes, Mexico, 20230
        • Rekruttering
        • Hospital Cardiologica Aguascalientes
        • Kontakt:
      • Aguascalientes, Mexico, 20230
        • Rekruttering
        • Fundación Cardiovascular de Aguascalientes A.C
        • Kontakt:
      • Culiacán, Mexico, 80230
        • Rekruttering
        • Centro Medico Culiacán
        • Kontakt:
      • Distrito Federal, Mexico, 03100
        • Rekruttering
        • Centro de Investigacion Biomedica y Farmaceutica, S.C.
        • Kontakt:
      • Guadalajara, Mexico, 44670
        • Rekruttering
        • CICEJ Centro de Investigacion Clinica Endocrinologica de Jalisco S.C.
        • Kontakt:
      • Guadalajara, Mexico, 45519
        • Rekruttering
        • Salud Cardiovascular
        • Kontakt:
      • Irapuato, Mexico, 36520
        • Rekruttering
        • Proactive CR Mexico S.A. de C.V.
        • Kontakt:
      • Monterrey, Mexico, 64460
        • Rekruttering
        • Hospital Universitario Dr Jose Eleuterio Gonzalez
        • Kontakt:
      • Monterrey, Mexico, 64060
        • Rekruttering
        • Cardiolink Clin Trials S.C.
        • Kontakt:
      • México, Mexico, 06700
        • Rekruttering
        • Clinstile S.A. de C.V.
        • Kontakt:
      • Tlalnepantla, Mexico, 54055
        • Rekruttering
        • Clinical Research Institute S.C.
        • Kontakt:
      • Torreón, Mexico, 27000
        • Rekruttering
        • Centro de Investigacion Medica Alberto Bazzoni S.A. de C.V.
        • Kontakt:
  • Polen
      • Bialystok, Polen, 15-540
        • Rekruttering
        • Univ. Clinic Hosp, Bialystok
        • Kontakt:
      • Bydgoszcz, Polen, 85231
        • Rekruttering
        • NZOZ Medical Center KERmed
        • Kontakt:
      • Bydgoszcz, Polen, 85-605
        • Rekruttering
        • Centrum Medyczne Intercor Sp. z o.o.
        • Kontakt:
      • Chojnice, Polen, 89-600
        • Rekruttering
        • Pratia Chojnice Medical Center
        • Kontakt:
      • Częstochowa, Polen, 42-217
        • Rekruttering
        • Medical Center Pratia Czestochowa
        • Kontakt:
      • Elblag, Polen, 82-300
        • Rekruttering
        • Trevo Clinic Centrum Medyczne
        • Kontakt:
      • Gdansk, Polen, 80-286
        • Rekruttering
        • Poradnia Kardiologiczna Jaroslaw Jurowiecki
        • Kontakt:
      • Gdynia, Polen, 81-157
        • Rekruttering
        • Individual Specialist Medical Practice Krzysztof Cymerman
        • Kontakt:
      • Katowice, Polen, 40-156
        • Rekruttering
        • Clinical Medical Research Sp. z o.o.
        • Kontakt:
      • Katowice, Polen, 40-081
        • Rekruttering
        • Pratia Katowice Medical Center
        • Kontakt:
      • Kielce, Polen, 25525
        • Ikke rekrutterer endnu
        • Specialistic Cardiology&Hypertension Out-patient Clin,Kielce
        • Kontakt:
      • Krakow, Polen, 30-727
      • Krakow, Polen, 30-082
        • Rekruttering
        • Leszek Bryniarski Specialized Medical Cabinet
        • Kontakt:
      • Krakow, Polen, 30-721
        • Rekruttering
        • Linden Sp. z o.o. sp.k.
        • Kontakt:
      • Legnica, Polen, 59-220
        • Rekruttering
        • Beata Miklaszewicz & Dariusz Dabrowski Cardiamed Sp. j.
        • Kontakt:
      • Lodz, Polen, 90-302
        • Rekruttering
        • SANTA FAMILIA Centrum Badan, Profilaktyki i Leczenia
        • Kontakt:
      • Lodz, Polen, 94-255
        • Rekruttering
        • Individual Specialized Practice
        • Kontakt:
      • Lowicz, Polen, 99-400
        • Rekruttering
        • Lowickie Cardiology Center
        • Kontakt:
      • Lublin, Polen, 20-601
        • Rekruttering
        • Zanamed Medical Clinic Sp. z o.o.
        • Kontakt:
      • Lublin, Polen, 20-362
        • Rekruttering
        • Velocity Nova Sp. z o.o.
        • Kontakt:
      • Olsztyn, Polen, 10 165
      • Oświęcim, Polen, 32-600
        • Ikke rekrutterer endnu
        • Medicome Sp. z o.o.
        • Kontakt:
      • Piaseczno, Polen, 05-500
      • Poznan, Polen, 61-853
        • Rekruttering
        • Non-Public Outpatient Clinic Neuro-Kard Ilkowski & Partners
        • Kontakt:
      • Przemyśl, Polen, 37-700
        • Ikke rekrutterer endnu
        • Padre Pio Regional Hospital in Przemysl
        • Kontakt:
      • Ruda Śląska, Polen, 41-710
        • Rekruttering
        • Aka-Med Centrum Sp. z o.o. S.K.
        • Kontakt:
      • Rzeszów, Polen, 35-055
        • Rekruttering
        • Centrum Medyczne Medyk
        • Kontakt:
      • Siedlce, Polen, 08-110
        • Rekruttering
        • Lukmed Lukasz Wozniak
        • Kontakt:
      • Skierniewice, Polen, 96-100
        • Rekruttering
        • Velocity Skierniewice Sp. z o.o
        • Kontakt:
      • Sochaczew, Polen, 96-500
        • Rekruttering
        • RCMed- Regionalne Centrum Medyczne
        • Kontakt:
      • Sopot, Polen, 81-717
        • Rekruttering
        • NZOZ Procordis, Cardiology Research Center of Sopot
        • Kontakt:
      • Staszów, Polen, 28-200
      • Szczecin, Polen, 70-240
        • Rekruttering
        • Sedimed Sp. z o.o.
        • Kontakt:
      • Warsaw, Polen, 00-215
        • Rekruttering
        • FutureMeds Sp. z o.o.
        • Kontakt:
      • Warsaw, Polen, 01-249
        • Rekruttering
        • Balsammedica Sp. z o. o.
        • Kontakt:
      • Warsaw, Polen, 02-172
        • Rekruttering
        • MTZ Clinical Research Powered by Pratia
        • Kontakt:
      • Wroclaw, Polen, 50-981
        • Rekruttering
        • 4. Military Clinical Hospital with Polyclinic SP ZOZ
        • Kontakt:
      • Wroclaw, Polen, 53-030
        • Rekruttering
        • Sedimed Sp. z o.o.
        • Kontakt:
      • Zamość, Polen, 22-400
        • Rekruttering
        • KO-MED Clinical Centers Zamosc
        • Kontakt:
      • Żarów, Polen, 58-130
        • Rekruttering
        • Centrum Medyczne Serafin med
        • Kontakt:
  • Rumænien
      • Baia Mare, Rumænien, 430031
        • Rekruttering
        • Spitalul Judetean De Urgenta Dr. Constantin Opris Baia Mare
        • Kontakt:
      • Baloteşti, Rumænien, 77015
        • Rekruttering
        • Spitalul Clinic De Urgenta Prof Dr Agrippa Ionescu
        • Kontakt:
      • Brasov, Rumænien, 500091
        • Rekruttering
        • S.C.Centrul Medical Unirea SRL
        • Kontakt:
      • Brăila, Rumænien, 810325
        • Rekruttering
        • Spitalul Judetean de Urgenta Braila
        • Kontakt:
      • Bucharest, Rumænien, 10192
        • Rekruttering
        • Clinica Medicala Data Plus SRL
        • Kontakt:
      • Bucharest, Rumænien, 050098
        • Rekruttering
        • Emergency University Hospital
        • Kontakt:
      • Bucharesti, Rumænien, 030463
        • Rekruttering
        • S.C. Policlinica CCBR S.R.L.
        • Kontakt:
      • Cluj-Napoca, Rumænien, 400015
      • Craiova, Rumænien, 200642
        • Rekruttering
        • Emergency County Hospital Craiova
        • Kontakt:
      • Iași, Rumænien, 700023
        • Rekruttering
        • S.C.Centrul Medical Unirea S.R.L.
        • Kontakt:
      • Oradea, Rumænien, 410169
        • Rekruttering
        • Spitalul Clinic Judetean de Urgenta Bihor
        • Kontakt:
      • Piteşti, Rumænien, 110424
      • Timișoara, Rumænien, 300362
      • Târgu Mureş, Rumænien, 540136
        • Rekruttering
        • Spitalul Clinic Judetean de Urgenta Targu Mures
        • Kontakt:
      • Târgu Mureş, Rumænien, 540143
        • Rekruttering
        • Podoleanu G. Cristian-Gheorghe-Calin
        • Kontakt:
      • Târgu Mureş, Rumænien, 540136
        • Rekruttering
        • Country Clinical Emergency Hospital, Targu-Mures
        • Kontakt:
  • Saudi Arabien
      • Jeddah, Saudi Arabien, 21589
        • Ikke rekrutterer endnu
        • King AbdulAziz University Hospital
        • Kontakt:
      • Riyadh, Saudi Arabien, 11525
        • Rekruttering
        • King Fahad Medical City
        • Kontakt:
      • Riyadh, Saudi Arabien, 11211
        • Rekruttering
        • King Faisal Specialist Hospital and Research Center
        • Kontakt:
      • Riyadh, Saudi Arabien, 11426
        • Rekruttering
        • King Abdulaziz Medical City
        • Kontakt:
      • Riyadh, Saudi Arabien, 11623
        • Rekruttering
        • King Saud Medical City
        • Kontakt:
  • Serbien
      • Belgrade, Serbien, 11000
        • Rekruttering
        • University Clinical Center of Serbia
        • Kontakt:
      • Belgrade, Serbien, 11000
        • Rekruttering
        • Institute for Cardiovascular diseases Dedinje
        • Kontakt:
      • Belgrade, Serbien, 11000
        • Rekruttering
        • Clinical Center " Dr Dragisa Misovic Dedinje"
        • Kontakt:
      • Belgrade, Serbien, 11080
        • Rekruttering
        • Clinical Hospital Center Zemun
        • Kontakt:
      • Belgrade, Serbien, 11000
        • Ikke rekrutterer endnu
        • Clinical Hospital Center Dr. Dragisa Misovic
        • Kontakt:
      • Kragujevac, Serbien, 34000
        • Rekruttering
        • University Clinical Center of Kragujevac
        • Kontakt:
      • Niš, Serbien, 18000
        • Rekruttering
        • University Clinical Center Nis
        • Kontakt:
      • Niška Banja, Serbien, 18205
        • Rekruttering
        • Institute for Treatment and Rehabilitation, Niska Banja
        • Kontakt:
      • Pančevo, Serbien, 26000
        • Rekruttering
        • General Hospital Pancevo
        • Kontakt:
      • Smederevo, Serbien, 11300
        • Rekruttering
        • General Hospital Sveti Luka
        • Kontakt:
      • Zaječar, Serbien, 19000
        • Rekruttering
        • Health Centre Zajecar
        • Kontakt:
  • Slovenien
      • Celje, Slovenien, 3000
      • Golnik, Slovenien, 4204
      • Jesenice, Slovenien, 4270
      • Ljubljana, Slovenien, 1000
        • Rekruttering
        • University Medical Center Ljubljana
        • Kontakt:
      • Murska Sobota, Slovenien, 9000
      • Trbovlje, Slovenien, 1420
  • Spanien
      • Badalona, Spanien, 08916
        • Rekruttering
        • Hospital Germans Trias i Pujol
        • Kontakt:
      • Barcelona, Spanien, 08035
        • Ikke rekrutterer endnu
        • Hospital Universitari Vall d'Hebron
        • Kontakt:
      • Barcelona, Spanien, 08023
        • Rekruttering
        • Hospital Quiron. I.C.U.
        • Kontakt:
      • El Palmar, Spanien, 30120
        • Rekruttering
        • Hospital Universitario Virgen de la Arrixaca
        • Kontakt:
      • L'Hospitalet de Llobregat, Spanien, 08907
        • Rekruttering
        • Hospital Universitari de Bellvitge
        • Kontakt:
      • Madrid, Spanien, 28041
        • Rekruttering
        • Hospital Universitario 12 de Octubre
        • Kontakt:
      • Madrid, Spanien, 28046
        • Rekruttering
        • Hospital Universitario La Paz
        • Kontakt:
      • Madrid, Spanien, 28007
        • Rekruttering
        • Hospital General Universitario Gregorio Marañón
        • Kontakt:
      • Madrid, Spanien, 28034
        • Rekruttering
        • Hospital Universitario Ramon Y Cajal
        • Kontakt:
      • Málaga, Spanien, 29010
        • Rekruttering
        • Hospital Universitario Virgen de la Victoria
        • Kontakt:
      • Sanlúcar de Barrameda, Spanien, 11540
        • Rekruttering
        • Hospital Virgen del Camino
        • Kontakt:
      • Santiago de Compostela, Spanien, 15706
        • Rekruttering
        • Complexo Hospitalario Universitario De Santiago
        • Kontakt:
      • Valencia, Spanien, 46014
        • Rekruttering
        • Hospital General Universitario de Valencia
        • Kontakt:
      • Valencia, Spanien, 46010
        • Rekruttering
        • Hospital Clinico Universitario de Valencia
        • Kontakt:
      • Valencia, Spanien, 46026
        • Rekruttering
        • Hospital Universitari i Politècnic La Fe
        • Kontakt:
      • Villamartin, Cardiz, Spanien, 11650
        • Rekruttering
        • Hospital Virgen de las Montañas
        • Kontakt:
  • Sydafrika
      • Bloemfontein, Sydafrika, 9301
      • Bloemfontein, Sydafrika, 9301
      • Cape Town, Sydafrika, 7500
      • Centurion, Sydafrika, 0157
      • Centurion, Sydafrika, 0157
      • Johannesburg, Sydafrika, 1862
        • Rekruttering
        • Chris Hani Baragwanath Hospital: Cardiology Department
        • Kontakt:
      • Somerset West, Sydafrika, 7130
      • Worcester, Sydafrika, 6850
  • Sydkorea
      • Bucheon-si, Sydkorea, 14754
        • Ikke rekrutterer endnu
        • SeJong General Hospital
        • Kontakt:
      • Busan, Sydkorea, 49241
        • Rekruttering
        • Pusan National University Hospital
        • Kontakt:
      • Busan, Sydkorea, 47392
        • Rekruttering
        • Inje University Busan Paik Hospital
        • Kontakt:
      • Busan, Sydkorea, 49201
        • Rekruttering
        • Dong-A University Hospital
        • Kontakt:
      • Cheongju-si, Sydkorea, 28644
        • Ikke rekrutterer endnu
        • Chungbuk National University Hospital
        • Kontakt:
      • Daegu, Sydkorea, 28644
        • Ikke rekrutterer endnu
        • Yeungnam University Medical Center
        • Kontakt:
      • Daejeon, Sydkorea, 35015
        • Ikke rekrutterer endnu
        • Chungnam National University Hospital
        • Kontakt:
      • Deagu, Sydkorea, 42601
        • Ikke rekrutterer endnu
        • Keimyung University Dongsan Hospital
        • Kontakt:
      • Gwangju, Sydkorea, 61469
        • Rekruttering
        • Chonnam National University Hospital
        • Kontakt:
      • Incheon, Sydkorea, 21565
        • Rekruttering
        • Gachon University Gil Medical Center
        • Kontakt:
      • Incheon, Sydkorea, 22332
        • Ikke rekrutterer endnu
        • Inha University Hospital
        • Kontakt:
      • Seongnam, Sydkorea, 13620
        • Rekruttering
        • Seoul National University Bundang Hospital
        • Kontakt:
      • Seoul, Sydkorea, 03080
        • Rekruttering
        • Seoul National University Hospital
        • Kontakt:
      • Seoul, Sydkorea, 06351
        • Rekruttering
        • Samsung Medical Center
        • Kontakt:
      • Seoul, Sydkorea, 03722
      • Seoul, Sydkorea, 08308
        • Rekruttering
        • Korea University Guro Hospital
        • Kontakt:
      • Seoul, Sydkorea, 06591
        • Ikke rekrutterer endnu
        • The Catholic University of Korea, Seoul St.Mary's Hospital
        • Kontakt:
      • Seoul, Sydkorea, 2841
        • Rekruttering
        • Korea University Anam Hospital
        • Kontakt:
      • Wonju-si, Gangwon State, Sydkorea, 26426
        • Rekruttering
        • Yonsei University Wonju Severance Christian Hospital
        • Kontakt:
      • Yangsan, Sydkorea, 50612
        • Ikke rekrutterer endnu
        • Pusan National University Yangsan Hospital
        • Kontakt:
  • Taiwan
      • Kaohsiung City, Taiwan, 82445
      • New Taipei City, Taiwan, 235
        • Rekruttering
        • Taipei Medical University-Shuang Ho Hospital
        • Kontakt:
      • Taichung, Taiwan, 40705
        • Rekruttering
        • Taichung Veterans General Hospital
        • Kontakt:
      • Taichung, Taiwan, 404327
        • Rekruttering
        • China Medical University Hospital
        • Kontakt:
      • Taipei, Taiwan, 114
        • Rekruttering
        • Tri-Service General Hospital
        • Kontakt:
      • Taipei, Taiwan, 100
        • Rekruttering
        • National Taiwan University Hospital
        • Kontakt:
      • Taipei, Taiwan, 11217
        • Rekruttering
        • Taipei Veterans General Hospital
        • Kontakt:
      • Taipei, Taiwan, 112
        • Rekruttering
        • Cheng Hsin General Hospital
        • Kontakt:
      • Taipei, Taiwan, 110
        • Rekruttering
        • Taipei Medical University Hospital
        • Kontakt:
      • Taoyuan City, Taiwan, 333
        • Rekruttering
        • Chang Gung Memorial Hospital, Linkou
        • Kontakt:
  • Tjekkiet
      • Brandýs nad Labem, Tjekkiet, 250 01
        • Rekruttering
        • Medicus Services s.r.o.
        • Kontakt:
      • Brandýs nad Labem, Tjekkiet, 25001
        • Rekruttering
        • Interni Ordinace s.r.o.
        • Kontakt:
      • Brno, Tjekkiet, 62500
        • Rekruttering
        • University Hospital Brno
        • Kontakt:
      • Brno, Tjekkiet, 625 00
        • Rekruttering
        • University Hospital Brno
        • Kontakt:
      • Brno, Tjekkiet, 602 00
        • Rekruttering
        • MUDr. Libor Nechvatal s.r.o.
        • Kontakt:
      • Brno, Tjekkiet, 602 00
      • Brno, Tjekkiet, 603 00
        • Rekruttering
        • MUDr. Karel Kamenik s.r.o
        • Kontakt:
      • Brno, Tjekkiet, 61500
        • Rekruttering
        • Vojenska nemocnice Brno
        • Kontakt:
      • Bílovec, Tjekkiet, 743 01
        • Rekruttering
        • MUDr. Hana Burianova
        • Kontakt:
      • Chrudim, Tjekkiet, 537 01
        • Rekruttering
        • MUDr. Jan Hubac s.r.o.
        • Kontakt:
      • Havlíčkův Brod, Tjekkiet, 580 01
        • Rekruttering
        • Regional Hospital Havlickuv Brod
        • Kontakt:
      • Jablonec nad Nisou, Tjekkiet, 46601
        • Rekruttering
        • Kardiologie KarMa s.r.o
        • Kontakt:
      • Jihlava, Tjekkiet, 586 33
      • Litovel, Tjekkiet, 784 01
        • Rekruttering
        • MUDr Petra Maskova PhD
        • Kontakt:
      • Mariánské Lázně, Tjekkiet, 353 01
        • Rekruttering
        • InterKardioML s.r.o.
        • Kontakt:
      • Prague, Tjekkiet, 140 21
        • Rekruttering
        • Institute for Clinical and Experimental Medicine
        • Kontakt:
      • Prague, Tjekkiet, 15006
        • Rekruttering
        • University Hospital Motol
        • Kontakt:
      • Prague, Tjekkiet, 11000
        • Rekruttering
        • Kardiologie Vinohrady s r o
        • Kontakt:
      • Prague, Tjekkiet, 10100
        • Rekruttering
        • MUDr. Jan Kvasnicka CSc
        • Kontakt:
      • Praha 4-Krc, Tjekkiet, 140 59
        • Rekruttering
        • University Thomayer´s Hospital
        • Kontakt:
      • Smiřice, Tjekkiet, 5000
        • Rekruttering
        • Internist Care s.r.o
        • Kontakt:
      • Trutnov, Tjekkiet, 541 01
        • Rekruttering
        • Kardiologicka ambulance MUDr. Ferkl s.r.o.
        • Kontakt:
      • Uherské Hradiště, Tjekkiet, 68601
        • Rekruttering
        • Clinical Trials Services s.r.o
        • Kontakt:
      • Uherské Hradiště, Tjekkiet, 68601
        • Ikke rekrutterer endnu
        • MUDr. Nina Zemkova s.r.o.
        • Kontakt:
      • Zlín, Tjekkiet, 76001
        • Rekruttering
        • Cardio Research s.r.o.
        • Kontakt:
  • Tyrkiet (Türkiye)
      • Adana, Tyrkiet (Türkiye), 01330
        • Rekruttering
        • Çukurova Ü. Tip Fak., Balcali Hastanesi, Kardiyoloji
        • Kontakt:
      • Afyonkarahisar, Tyrkiet (Türkiye), 03200
        • Rekruttering
        • Afyon Kocatepe University Medical Faculty
        • Kontakt:
      • Ankara, Tyrkiet (Türkiye), 06170
        • Ikke rekrutterer endnu
        • Etlik City Hospital
        • Kontakt:
      • Elâzığ, Tyrkiet (Türkiye), 23119
        • Rekruttering
        • Firat University Hospital
        • Kontakt:
      • Erzurum, Tyrkiet (Türkiye), 25240
        • Rekruttering
        • Ataturk Universitesi Tip Fakultesi
        • Kontakt:
      • Eskişehir, Tyrkiet (Türkiye), 26480
        • Rekruttering
        • Osmangazi Uni Medical Faculty
        • Kontakt:
      • Gaziantep, Tyrkiet (Türkiye), 27310
        • Rekruttering
        • Gaziantep University Medical Faculty Sahinbey Educational Research Hospital
        • Kontakt:
      • Istanbul, Tyrkiet (Türkiye), 34899
        • Ikke rekrutterer endnu
        • Medical Park Pendik Hospital
        • Kontakt:
      • Istanbul, Tyrkiet (Türkiye), 34668
        • Ikke rekrutterer endnu
        • Siyami Ersek Gogus Kalp ve Damar Cerrahisi Hastanesi
        • Kontakt:
      • Istanbul, Tyrkiet (Türkiye), 34899
        • Rekruttering
        • Marmara University Pendik Training and Research Hospital
        • Kontakt:
      • Kütahya, Tyrkiet (Türkiye), 43040
        • Rekruttering
        • Kutahya Health Science University
        • Kontakt:
      • Malatya, Tyrkiet (Türkiye), 44280
        • Rekruttering
        • Inonu Universitesi Tip Fakultesi Gogus Hastaliklari ABD
        • Kontakt:
      • Mersin, Tyrkiet (Türkiye), 33020
        • Rekruttering
        • Mersin University Medical Faculty
        • Kontakt:
      • Trabzon, Tyrkiet (Türkiye), 61080
        • Ikke rekrutterer endnu
        • KTU Tip Fakultesi Farabi Hastanesi
        • Kontakt:
  • Tyskland
      • Aachen, Tyskland, 52074
      • Bad Friedrichshall, Tyskland, 74177
      • Berlin, Tyskland, 13353
      • Berlin, Tyskland, 13407
      • Berlin, Tyskland, 12203
      • Berlin, Tyskland, 10789
      • Berlin, Tyskland, 13347
      • Berlin, Tyskland, 10787
        • Rekruttering
        • Velocity Clinical Research Germany GmbH, Berlin
        • Kontakt:
      • Berlin, Tyskland, 13509
      • Bonn, Tyskland, 53127
      • Dessau, Tyskland, 06846
      • Dresden, Tyskland, 01067
        • Ikke rekrutterer endnu
        • Städtisches Klinikum Dresden
        • Kontakt:
      • Dresden, Tyskland, 01099
        • Rekruttering
        • Facharztzentrum Dresden-Neustadt Betriebsgesellschaft mbH
        • Kontakt:
      • Erfurt, Tyskland, 99089
      • Frankfurt, Tyskland, 60590
      • Frankfurt, Tyskland, 60596
      • Hamburg, Tyskland, 22143
        • Rekruttering
        • Velocity Clinical Research Germany GmbH, Hamburg
        • Kontakt:
      • Hanover, Tyskland, 30625
      • Jena, Tyskland, 07747
      • Kamp-Lintfort, Tyskland, 47475
      • Kiel, Tyskland, 24105
        • Rekruttering
        • Universitätsklinikum Schleswig-Holstein, Campus Kiel
        • Kontakt:
      • Langen, Tyskland, 63225
        • Rekruttering
        • Asklepios Klinik Langen-Seligenstadt GmbH
        • Kontakt:
      • Leipzig, Tyskland, 04177
        • Rekruttering
        • Velocity Clinical Research Germany GmbH, Leipzig
        • Kontakt:
      • Lüneburg, Tyskland, 21339
      • Neuwied, Tyskland, 56564
      • Nuremberg, Tyskland, 90402
        • Rekruttering
        • Gemeinschaftspraxis Dres Haggenmiller/Jeserich
        • Kontakt:
      • Papenburg, Tyskland, 26871
      • Regensburg, Tyskland, 93053
      • Straubing, Tyskland, 94315
        • Ikke rekrutterer endnu
        • Kardiologische Praxis im Steiner Thor
        • Kontakt:
      • Stuhr, Tyskland, 28816
      • Wallerfing, Tyskland, 94574
      • Wermsdorf, Tyskland, 04779
      • Wiesbaden, Tyskland, 65189
        • Rekruttering
        • Velocity Clinical Research Germany GmbH, Wiesbaden
        • Kontakt:
  • Ungarn
      • Baja, Ungarn, 6500
      • Budapest, Ungarn, 1122
      • Budapest, Ungarn, 1083
      • Budapest, Ungarn, 1096
      • Budapest, Ungarn, 1051
      • Budapest, Ungarn, 1132
      • Budapest, Ungarn, 1152
      • Budapest, Ungarn, 1036
      • Budapest, Ungarn, 1066
      • Budapest, Ungarn, 1023
        • Rekruttering
        • Betegapolo Irgalmasrend Budai Irgalmasrendi Korhaz
        • Kontakt:
      • Budapest, Ungarn, 1134
      • Gyula, Ungarn, 5700
      • Hatvan, Ungarn, 3000
      • Kecskemét, Ungarn, 6000
      • Miskolc, Ungarn, 3526
        • Rekruttering
        • Borsod-Abauj-Zemplen Megyei Korhaz es Egyetemi Oktato Korhaz
        • Kontakt:
      • Miskolc, Ungarn, 3530
      • Orosháza, Ungarn, 5900
      • Pécs, Ungarn, 7623
      • Pécs, Ungarn, 7624
      • Pécs, Ungarn, 7635
      • Szeged, Ungarn, 6726
      • Szekszárd, Ungarn, 7100
      • Szolnok, Ungarn, 5000
        • Rekruttering
        • Jasz-Nagykun-Szolnok Megyei Hetenyi G. Korhaz-Rendelointezet
        • Kontakt:
      • Zalaegerszeg, Ungarn, 8900
  • Vietnam
      • Da Nang, Vietnam, 550000
        • Ikke rekrutterer endnu
        • Da Nang Hospital
        • Kontakt:
      • Hanoi, Vietnam, 100000
      • Ho Chi Minh City, Vietnam, 700000
        • Rekruttering
        • Nguyen Tri Phuong Hospital
        • Kontakt:
      • Ho Chi Minh City, Vietnam, 700000
        • Rekruttering
        • Tam Duc Heart Hospital
        • Kontakt:
      • Ho Chi Minh City, Vietnam, 700000
      • Ho Chi Minh City, Vietnam, 70000
        • Rekruttering
        • Thong Nhat Hospital HCMC
        • Kontakt:
      • Ho Chi Minh City, Vietnam, 748806
        • Rekruttering
        • University Medical Center HCMC
        • Kontakt:

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

18 år og ældre (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Køn, der er berettiget til at studere

Alle

Beskrivelse

Inclusion criteria:

  1. At least 18 years old and at least of the legal age of consent in countries where it is greater than 18 years

  2. Signed and dated written informed consent in accordance with ICH-GCP and local legislation prior to admission to the trial

  3. Male or female participants. Women of childbearing potential (WOCBP) must be ready and able to use highly effective methods of birth control per International Conference on Harmonisation (ICH) M3 (R2) that result in a low failure rate of less than 1% per year when used consistently and correctly. A list of contraception methods meeting these criteria and instructions on the duration of their use is provided in the participant information

  4. Chronic Heart failure (HF) diagnosed at least 3 months before Visit 1, and in New York Heart Association (NYHA) class II-IV at Visit 1, with left ventricular ejection fraction (LVEF) ≥40% per local reading. A historical LVEF may be used if it was measured within 12 months prior to Visit 1, or the LVEF may be measured after study consent has been obtained and before randomisation at Visit 2

  5. Presence of structural heart abnormality (confirmed by any imaging modality; i.e. echocardiography at Visit 1, as defined by left ventricular hypertrophy or left atrial enlargement). Historical imaging may be used if performed within 12 months prior to Visit 1, or imaging may be completed after study consent has been obtained and before Visit 2

  6. Elevated N-terminal pro-brain natriuretic peptide (NT-proBNP) at Visit 1, analysed at the central laboratory at Visit 1:

    1. in participants with body mass index (BMI) <27 kg/m²: ≥300 pg/mL for participants without atrial fibrillation (Afib) or atrial flutter (Aflutter) (at Visit 1 electrocardiogram (ECG)) and ≥900 pg/mL for participants with Afib or Aflutter (at Visit 1 ECG)
    2. in participants with BMI ≥27 kg/m² to <35 kg/m²: ≥220 pg/mL for participants without Afib or Aflutter (at Visit 1 ECG) and ≥660 pg/mL for participants with Afib or Aflutter (at Visit 1 ECG)
    3. in participants with BMI ≥35 kg/m²: ≥125 pg/mL for participants without Afib or Aflutter (at Visit 1 ECG) and ≥375 pg/mL for participants with Afib or Aflutter (at Visit 1 ECG)

  7. At least one of the following:

    • Currently treated with diuretic therapy e.g. loop diuretics or thiazides, and on a stable dose for at least 1 week prior to Visit 1

    • Documented hospitalisation for HF within 6 months prior to Visit 1

    • Elevated NT-proBNP at Visit 1, analysed at the central laboratory at Visit 1

      • in participants without Afib or Aflutter (at Visit 1 ECG): ≥900 pg/mL
      • for participants with Afib or Aflutter (at Visit 1 ECG): ≥1800 pg/mL

    • Urine albumin-to-creatinine ratio (UACR) ≥30 mg/g, analysed at the central laboratory at Visit 1

  8. Treated according to best possible standard of care (SOC) (disregarding Sodium-dependent glucose co-transporter 2 inhibitors (SGLT2is) and Mineralocorticoid receptor antagonists (MRAs)) in accordance with applicable HF local/international guidelines and judgment of the investigator Further inclusion criteria apply.

Exclusion criteria:

  1. Treatment with an mineralocorticoid receptor antagonist (MRA) (e.g. spironolactone, eplerenone, finerenone) within 14 days prior to Visit 1 or requiring such treatment before randomisation or planned during the trial based on the judgment of the investigator. Treatment with MRA should not be interrupted with the intention of enrolment into the study

  2. Treatment with amiloride, or other potassium-sparing diuretic within 14 days prior to Visit 1 or requiring such treatment before randomisation or planned during the trial based on the judgment of the investigator

  3. Receiving the following treatments:

    • a direct renin inhibitor (e.g. aliskiren) at Visit 2

    • more than one angiotensin-converting enzyme inhibitor (ACEI), angiotensin receptor blocker (ARB) or angiotensin receptor-neprilysin inhibitor (ARNI) used simultaneously at Visit 2

    • In case of acute decompensated HF:

      • i.v. inotrope, i.v. vasodilating drug (e.g. nitrate, nitroprusside), or i.v. natriuretic peptide (e.g. nesiritide, carperitide), or mechanical support (e.g. intra-aortic balloon pump, endotracheal intubation, mechanical ventilation, any ventricular assist device) within 24 hours prior to randomisation (Visit 2)
      • i.v. diuretic with a dose that has been increased/intensified within 6 hours prior to randomisation (a stable dose of an i.v. diuretic is not exclusionary)

    • Systemic mineralocorticoid replacement therapy (e.g. fludrocortisone) at Visit 2

    • Other aldosterone synthase inhibitors, e.g. baxdrostat at Visit 2 or planned during the trial

  4. Myocardial infarction (MI), transient ischemic attack (TIA), stroke, coronary artery bypass graft (CABG) surgery, heart valve surgery/intervention or any other major surgery (major according to the investigator's assessment) within 90 days prior to Visit 2, or scheduled for major elective surgery (e.g. hip replacement, coronary artery bypass graft surgery/CABG)

  5. Percutaneous coronary intervention (PCI) ( scheduled or unscheduled) or any angiography using iodinated contrast agents in the 7 days prior to Visit 2

  6. Heart transplant recipient, awaiting heart transplant, or currently implanted left ventricular assist device (LVAD)

  7. Known cardiomyopathy based on infiltrative diseases (e.g. amyloidosis), accumulation diseases (e.g. haemochromatosis, Fabry disease), muscular dystrophies, hypertrophic obstructive cardiomyopathy or genetic hypertrophic cardiomyopathy,known pericardial constriction, or cardiomyopathy with potentially reversible cause such as stress or peripartum cardiomyopathy or cardiomyopathy induced by chemotherapy within the 12 months prior to Visit 1 and until Visit 2

  8. Acute inflammatory heart disease, such as acute myocarditis, within the 90 days preceding prior to Visit 1 and until Visit 2

  9. Known severe valvular heart disease (obstructive or regurgitant), as per investigator's judgment, or valvular heart disease scheduled for surgical or invasive procedures at Visit 1, or anticipated invasive treatment during the study Further exclusion criteria apply.

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Primært formål: Behandling
  • Tildeling: Randomiseret
  • Interventionel model: Parallel tildeling
  • Maskning: Tredobbelt

Våben og indgreb

Deltagergruppe / Arm
Intervention / Behandling
Eksperimentel: Vicadrostat/empagliflozin
Medicin: vicadrostat

vicadrostat

Medicin: empagliflozin

empagliflozin
Placebo komparator: placebo/empagliflozin
Medicin: empagliflozin

empagliflozin

Medicin: placebo

placebo matching vicadrostat

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Tidsramme
Tid til første tilfælde af kardiovaskulær (CV) død, hospitalsindlæggelse for hjertesvigt (HHF) eller akut hjertesvigt (HF) besøg
Tidsramme: op til 42 måneder
op til 42 måneder

Sekundære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Nøglesekundært endepunkt: Forekomst af HHF'er (første og tilbagevendende)
Tidsramme: op til 42 måneder
op til 42 måneder
Nøgle sekundært endepunkt: Tid til CV død
Tidsramme: op til 42 måneder
op til 42 måneder
Nøglesekundært endepunkt: Tid til dødelighed af alle årsager
Tidsramme: op til 42 måneder
op til 42 måneder
Tid til første HHF
Tidsramme: op til 42 måneder
op til 42 måneder
Absolut ændring fra baseline i KCCQ-TSS i uge 52
Tidsramme: ved baseline, i uge 52
ved baseline, i uge 52
Nøgle sekundært endepunkt: Tid til den første hændelse af CV død eller HHF
Tidsramme: op til 42 måneder
op til 42 måneder
Absolut ændring fra baseline i KCCQ-OSS i uge 52
Tidsramme: ved baseline, i uge 52
ved baseline, i uge 52
Absolut ændring fra baseline i systolisk blodtryk (SBP) [mmHg] i uge 32 hos deltagere med baseline SBP ≥130 mmHg
Tidsramme: ved baseline i uge 32
ved baseline i uge 32
Absolut chance fra baseline i diastolisk blodtryk (DBP) [mmHg] i uge 32 hos deltagere med baseline DBP ≥80 mmHg
Tidsramme: ved baseline i uge 32
ved baseline i uge 32
Key secondary endpoint: Absolute change from baseline in Kansas City Cardiomyopathy Questionnaire Total Symptom Score (KCCQ-TSS) at Week 32
Tidsramme: at baseline, at week 32

The Kansas City Cardiomyopathy Questionnaire is a patient-reported outcome instrument for use in clinical investigations in heart failure.

The Total Symptom Score measures the following aspects of symptom experience in two domain scores:

The "Symptom Frequency Domain" assesses frequency of the following experiences:

  • Lower extremity swelling in the morning
  • Fatigue limiting patients' ability to do what they want
  • Dyspnea limiting patients' ability to do what they want
  • Dyspnea forcing patients to sleep upright/elevated

The "Symptom Burden Domain" assesses bothersomeness of the following symptoms:

  • Fatigue
  • Dyspnea
  • Lower extremity swelling All KCCQ scores are scaled from 0 to 100 and frequently summarized in 25-point ranges, where scores represent health status as follows: 0 to 24: very poor to poor; 25 to 49: poor to fair; 50 to 74: fair to good; and 75 to 100: good to excellent.
at baseline, at week 32
Time to first occurrence of death from kidney failure, chronic dialysis* or renal transplant or onset of sustained reduction of ≥50% eGFR from baseline** or onset of sustained eGFR (CKD-EPI)cr <10 mL/min/1.73 m2 (composite renal endpoint)
Tidsramme: up to 42 months

* chronic dialysis is defined as dialysis continuing for at least 30 days

** using the Chronic Kidney Disease Epidemiology Collaboration creatinine equation ((CKD-EPI)cr)
up to 42 months
Absolute change from baseline in KCCQ Clinical Summary Score (KCCQ-CSS) at Week 32
Tidsramme: at baseline, at week 32

The KCCQ Clinical Summary Score is a composite of the Total Symptom Score and Physical Limitations Score.

The "Physical Limitations Score" measures the following physical limitations:

  • Dressing
  • Showering/bathing
  • Walking one block on level ground
  • Doing yardwork, housework or carrying groceries
  • Climbing a flight of stairs without stopping
  • Hurrying or jogging as if to catch a bus All KCCQ scores are scaled from 0 to 100 and frequently summarized in 25-point ranges, where scores represent health status as follows: 0 to 24: very poor to poor; 25 to 49: poor to fair; 50 to 74: fair to good; and 75 to 100: good to excellent.
at baseline, at week 32
Absolute change from baseline in KCCQ-OSS at Week 32
Tidsramme: at baseline, at week 32

The Kansas City Cardiomyopathy Questionnaire - overall summary score (KCCQ-OSS) is a combination of the symptom [domain], physical limitations, social limitations, and quality of life domains.

All KCCQ scores are scaled from 0 to 100 and frequently summarized in 25-point ranges, where scores represent health status as follows: 0 to 24: very poor to poor; 25 to 49: poor to fair; 50 to 74: fair to good; and 75 to 100: good to excellent.
at baseline, at week 32

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Boehringer Ingelheim

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Hjælpsomme links

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

17. juni 2024

Primær færdiggørelse (Anslået)

22. maj 2028

Studieafslutning (Anslået)

22. maj 2028

Datoer for studieregistrering

Først indsendt

10. maj 2024

Først indsendt, der opfyldte QC-kriterier

21. maj 2024

Først opslået (Faktiske)

22. maj 2024

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

28. oktober 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

27. oktober 2026

Sidst verificeret

1. oktober 2026

Mere information

Begreber relateret til denne undersøgelse

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

  • 1378-0020
  • 2023-509706-30-00 (Registry Identifier: CTIS)
  • U1111-1302-4422 (Registry Identifier: WHO International Clinical Trials Registry Platform (ICTRP))
  • 2023 (U.S. NIH-bevilling/kontrakt)

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

JA

IPD-planbeskrivelse

Once the criteria in section "Time Frame" are fulfilled, researchers can use the following link https://www.clinicalstudies.boehringer-ingelheim.com/msw/datasharing to request access to the clinical study documents regarding this study, and upon a signed "Document Sharing Agreement".

Furthermore, researchers can request access to the clinical study data, for this and other listed studies, after the submission of a research proposal and according to the terms outlined in the website.

IPD-delingstidsramme

One year after the approval has been granted by major Regulatory Authorities and after the primary manuscript has been accepted for publication, or after termination of the development program.

IPD-delingsadgangskriterier

For study documents - upon signing of a 'Document Sharing Agreement'. For study data - 1. after the submission and approval of the research proposal (checks will be performed by the sponsor and/or the independent review panel, including checking that the planned analysis does not compete with sponsor's publication plan); 2. and upon signing of a legal agreement.

IPD-deling Understøttende informationstype

  • STUDY_PROTOCOL
  • SAP
  • CSR

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

Studerer et amerikansk FDA-reguleret lægemiddelprodukt

Ja

Studerer et amerikansk FDA-reguleret enhedsprodukt

Ingen

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Abonner