- ICH GCP
- Register voor klinische proeven in de VS.
- Klinische proef NCT02408952
Screening op alcohol- en drugsgebruik door jongeren: een onderzoek onder eerstelijnszorgverleners
14 juli 2023 bijgewerkt door: Kaiser Permanente
Deze studie evalueert de implementatie en effectiviteit van twee modaliteiten van screening, korte interventie en verwijzing naar behandeling (SBIRT) om het gebruik van alcohol en andere drugs (AOD) door adolescenten in een grote kindergeneeskundekliniek te verminderen.
Studie Overzicht
Toestand
Actief, niet wervend
Conditie
Interventie / Behandeling
Gedetailleerde beschrijving
Gezondheidssystemen hebben Screening, Brief Intervention and Referral to Treatment (SBIRT) voor adolescenten niet geïmplementeerd, ondanks onderzoek dat de effectiviteit ervan aantoont.
Op basis van eerder onderzoek dat barrières identificeerde voor AOD-screening voor adolescenten in de pediatrische eerstelijnszorg (PC) en een pilotstudie waaruit bleek dat SBIRT haalbaar was, goed werd ontvangen en verwijzingen naar en het starten van gespecialiseerde behandeling bevorderde, stelt de huidige onderzoeksaanvraag voor om 45 Eerstelijnsartsen (PCP's) in de kindergeneeskundekliniek van een medisch centrum binnen een groot, beheerd zorgsysteem, Kaiser Permanente Noord-Californië, naar drie takken - 1) Gebruikelijke zorg; 2) SBIRT geleverd door PCP's; en 3) SBIRT geleverd door specialisten op het gebied van gedragsgeneeskunde (BMS).
Het doel van de studie is om de implementatie, effectiviteit en kosteneffectiviteit van SBIRT voor adolescenten in PC in de drie onderzoeksarmen te vergelijken.
Patiënten zullen op bewijzen gebaseerde screening en AOD-beoordelingsmaatregelen voltooien die zijn ingebed in het elektronische medische dossier (EMD) van het gezondheidsplan.
Er zal een gemengd model worden gebruikt om implementatieresultaten (percentages van screening en identificatie, korte interventie, verwijzing naar behandeling met chemische afhankelijkheid en start van de behandeling) en effectiviteit (patiëntresultaten van AOD-gebruik en onthouding) na 12 maanden te vergelijken.
Het model houdt rekening met de intra-klasse correlaties tussen patiënten binnen zorgverleners.
Kosteneffectiviteit ten opzichte van implementatie en patiëntuitkomsten zullen worden onderzocht.
Belemmeringen en facilitators van implementatie, en haalbaarheid via kwalitatieve interviews met clinici en bestuurders zullen ook worden onderzocht.
De studie is belangrijk omdat het problemen onderzoekt die moeten worden aangepakt om een wijdverspreide aanpassing van SBIRT aan te moedigen.
De voorgestelde interventies zijn zeer haalbaar in de huidige omgeving van gezondheidshervormingen dankzij meer middelen en training voor federaal gekwalificeerde gezondheidscentra en particuliere gezondheidsplannen.
Het is innovatief in het gebruik van de EMR om de klinische praktijk te veranderen en AOD systematisch te integreren in pc, en als een platform voor het verzamelen van onderzoeksgegevens.
Studietype
Ingrijpend
Inschrijving (Werkelijk)
9084
Fase
- Niet toepasbaar
Contacten en locaties
In dit gedeelte vindt u de contactgegevens van degenen die het onderzoek uitvoeren en informatie over waar dit onderzoek wordt uitgevoerd.
Studie Locaties
-
-
California
-
Oakland, California, Verenigde Staten, 94612
- Stacy A Sterling
-
-
Deelname Criteria
Onderzoekers zoeken naar mensen die aan een bepaalde beschrijving voldoen, de zogenaamde geschiktheidscriteria. Enkele voorbeelden van deze criteria zijn iemands algemene gezondheidstoestand of eerdere behandelingen.
Geschiktheidscriteria
Leeftijden die in aanmerking komen voor studie
12 jaar tot 80 jaar (Kind, Volwassen, Oudere volwassene)
Accepteert gezonde vrijwilligers
Ja
Beschrijving
Er zijn twee onderzoekspopulaties zoals hieronder beschreven, dus het grote leeftijdsgrensbereik.
Inclusiecriteria:
- Alle adolescente eerstelijnszorgverleners in de pediatrische eerstelijnskliniek zullen worden opgenomen.
- Alle elektronische patiëntendossiers van adolescenten in de leeftijd van 12-18 jaar in de eerstelijns kindergeneeskunde zullen worden onderzocht.
Uitsluitingscriteria:
- Eerstelijnszorgverleners voor adolescenten die niet werkzaam zijn op de onderzoekslocatie van de pediatrische eerstelijnskliniek, worden uitgesloten.
- Elektronische dossiers van adolescenten die geen deel uitmaken van de pediatrische kliniek van de onderzoekslocatie worden uitgesloten.
Studie plan
Dit gedeelte bevat details van het studieplan, inclusief hoe de studie is opgezet en wat de studie meet.
Hoe is de studie opgezet?
Ontwerpdetails
- Primair doel: Screening
- Toewijzing: Gerandomiseerd
- Interventioneel model: Faculteitstoewijzing
- Masker: Geen (open label)
Wapens en interventies
Deelnemersgroep / Arm |
Interventie / Behandeling |
|---|---|
|
Experimenteel: Huisarts in de eerste lijn
Als wordt vastgesteld dat de adolescent risico loopt op middelengebruik, wordt de screening en de korte verwijzing naar de geleverde behandeling verzorgd door de huisarts
|
De screening, korte interventie en verwijzing naar behandeling wordt verzorgd door de huisarts
|
|
Experimenteel: Gedragsgeneeskundig specialist
Als de adolescent risico loopt op middelengebruik, de screening en korte interventie doorverwijzing naar behandeling door de gedragsgeneeskundig specialist
|
De screening, korte interventie en verwijzing naar behandeling wordt verzorgd door de gedragsgeneeskundig specialist.
|
|
Geen tussenkomst: Gebruikelijke zorg
De zorg wordt zoals gebruikelijk toegediend
|
Wat meet het onderzoek?
Primaire uitkomstmaten
Uitkomstmaat |
Maatregel Beschrijving |
Tijdsspanne |
|---|---|---|
|
Screening tarief
Tijdsspanne: Initiële screening rate - bij index goed bezoek
|
Het percentage patiënten dat wordt gescreend met de Teen Well Check Questionnaire AOD-gebruiks- of Stemmingssymptoomvragen, onder alle patiënten met Teen Well-kind-bezoeken.
|
Initiële screening rate - bij index goed bezoek
|
|
Probleem Identificatiegraad
Tijdsspanne: Eerste probleemidentificatiepercentage - bij indexbezoek, na screening
|
Het percentage gescreende patiënten dat in de afgelopen 12 maanden "ja" antwoordde op AOD-gebruik of stemmingssymptomen en "ja" op ten minste één niet-auto-CRAFFT-vraag.
(In een auto zitten met iemand die AOD gebruikt, heeft misschien niet te maken met het probleem van het kind, maar met het hebben van een ouder/andere volwassene die onder invloed van alcohol heeft gereden).
|
Eerste probleemidentificatiepercentage - bij indexbezoek, na screening
|
|
Beoordelingspercentage
Tijdsspanne: Binnen 2 weken na indexeringsbezoekdatum
|
Percentage patiënten dat positief screent op alcohol of andere drugs, of risico's voor de geestelijke gezondheid, dat verder wordt beoordeeld met behulp van de CRAFFT-tool.
|
Binnen 2 weken na indexeringsbezoekdatum
|
|
Kort interventietarief
Tijdsspanne: Binnen 14 dagen na beoordeling bij indexputbezoek
|
Het aandeel patiënten dat binnen 14 dagen een interventie krijgt, onder degenen die zijn geïdentificeerd met AOD-risico (gebaseerd op CRAFFT-score).
Gedocumenteerd in EPD door clinici, met behulp van een ICD-9 Administratieve V-code voor begeleiding bij middelengebruik of gedragsbegeleiding.
|
Binnen 14 dagen na beoordeling bij indexputbezoek
|
|
Verwijzing naar gespecialiseerde behandeling tarief
Tijdsspanne: Binnen 6 maanden na index goed bezoek
|
Het percentage patiënten dat wordt doorverwezen naar een gespecialiseerde gedragstherapie, onder degenen die via de CRAFFT zijn geïdentificeerd als een dergelijke behandeling nodig hebben.
Gedocumenteerd in het EPD.
|
Binnen 6 maanden na index goed bezoek
|
Secundaire uitkomstmaten
Uitkomstmaat |
Maatregel Beschrijving |
Tijdsspanne |
|---|---|---|
|
Initiatie van speciale gedragsgezondheidsbehandelingen
Tijdsspanne: Binnen 2 jaar na de interventie
|
Gedefinieerd als het percentage verwezen, dat ten minste één speciaal bezoek heeft gehad op het gebied van gedragsgezondheid onder degenen die zijn geïdentificeerd met een gedragsgezondheidsprobleem.
Gedocumenteerd in het EPD.
|
Binnen 2 jaar na de interventie
|
|
Alcohol- en ander drugsgebruik
Tijdsspanne: Gebruik in de afgelopen 6 maanden, 1 en 2 jaar na de interventie
|
Alcohol- en drugsgebruik: De items in het EPD meten het gebruik van alcohol, marihuana en andere drugs en tabak in de afgelopen 30 dagen en 6 maanden, inclusief dagen van gebruik, geconsumeerde hoeveelheid (alle, 3+ en 5+ drankjes) en dagen van binge drinken (3+ en 5+).
|
Gebruik in de afgelopen 6 maanden, 1 en 2 jaar na de interventie
|
|
Middelen Gebruiksgerelateerde uitkomsten
Tijdsspanne: in de afgelopen 6 maanden, 1 en 2 jaar na de interventie
|
AOD-gerelateerde juridische, school- en gezinsproblemen: De EPD-vragen bevatten ook maatregelen uit de Comprehensive Adolescent Severity Inventory (CASI),148 een semi-gestructureerde vragenlijst die de gezondheid en het functioneren van adolescenten meet op het gebied van onderwijs, juridische zaken en gezinsrelaties.
|
in de afgelopen 6 maanden, 1 en 2 jaar na de interventie
|
Medewerkers en onderzoekers
Hier vindt u mensen en organisaties die betrokken zijn bij dit onderzoek.
Sponsor
Publicaties en nuttige links
De persoon die verantwoordelijk is voor het invoeren van informatie over het onderzoek stelt deze publicaties vrijwillig ter beschikking. Dit kan gaan over alles wat met het onderzoek te maken heeft.
Algemene publicaties
- Institute of Medicine (US) Committee on Quality of Health Care in America. Crossing the Quality Chasm: A New Health System for the 21st Century. Washington (DC): National Academies Press (US); 2001. Available from http://www.ncbi.nlm.nih.gov/books/NBK222274/
- Cabana MD, Rand CS, Powe NR, Wu AW, Wilson MH, Abboud PA, Rubin HR. Why don't physicians follow clinical practice guidelines? A framework for improvement. JAMA. 1999 Oct 20;282(15):1458-65. doi: 10.1001/jama.282.15.1458.
- Killip S, Mahfoud Z, Pearce K. What is an intracluster correlation coefficient? Crucial concepts for primary care researchers. Ann Fam Med. 2004 May-Jun;2(3):204-8. doi: 10.1370/afm.141.
- Windle M, Spear LP, Fuligni AJ, Angold A, Brown JD, Pine D, Smith GT, Giedd J, Dahl RE. Transitions into underage and problem drinking: developmental processes and mechanisms between 10 and 15 years of age. Pediatrics. 2008 Apr;121 Suppl 4(Suppl 4):S273-89. doi: 10.1542/peds.2007-2243C.
- Knight JR, Sherritt L, Shrier LA, Harris SK, Chang G. Validity of the CRAFFT substance abuse screening test among adolescent clinic patients. Arch Pediatr Adolesc Med. 2002 Jun;156(6):607-14. doi: 10.1001/archpedi.156.6.607.
- Schmittdiel JA, Shortell SM, Rundall TG, Bodenheimer T, Selby JV. Effect of primary health care orientation on chronic care management. Ann Fam Med. 2006 Mar-Apr;4(2):117-23. doi: 10.1370/afm.520.
- Selby JV, Uratsu CS, Fireman B, Schmittdiel JA, Peng T, Rodondi N, Karter AJ, Kerr EA. Treatment intensification and risk factor control: toward more clinically relevant quality measures. Med Care. 2009 Apr;47(4):395-402. doi: 10.1097/mlr.0b013e31818d775c.
- Saunders KW, Davis RL, Stergachis A. Group Health Cooperative. In: Strom BL, ed. Pharmacoepidemiology. 4th ed. New York: Wiley, 2005:223-239
- Selby JV, Smith DH, Johnson ES, et al. Kaiser Permanente Medical Care Program. In: Strom BL, ed. Pharmacoepidemiology. 4th ed. New York: Wiley, 2005:241-259
- Babor TE, Higgins-Biddle J, Dauser D, Higgins P, Burleson JA. Alcohol screening and brief intervention in primary care settings: implementation models and predictors. J Stud Alcohol. 2005 May;66(3):361-8. doi: 10.15288/jsa.2005.66.361.
- Brindis C, Park MJ, Ozer EM, Irwin CE Jr. Adolescents' access to health services and clinical preventive health care: crossing the great divide. Pediatr Ann. 2002 Sep;31(9):575-81. doi: 10.3928/0090-4481-20020901-10. No abstract available.
- Blum R. Physicians' assessment of deficiencies and desire for training in adolescent care. J Med Educ. 1987 May;62(5):401-7. doi: 10.1097/00001888-198705000-00005.
- Shrier LA, Harris SK, Kurland M, Knight JR. Substance use problems and associated psychiatric symptoms among adolescents in primary care. Pediatrics. 2003 Jun;111(6 Pt 1):e699-705. doi: 10.1542/peds.111.6.e699.
- Cowell AJ, Bray JW, Mills MJ, Hinde JM. Conducting economic evaluations of screening and brief intervention for hazardous drinking: Methods and evidence to date for informing policy. Drug Alcohol Rev. 2010 Nov;29(6):623-30. doi: 10.1111/j.1465-3362.2010.00238.x.
- Ockene JK, Adams A, Hurley TG, Wheeler EV, Hebert JR. Brief physician- and nurse practitioner-delivered counseling for high-risk drinkers: does it work? Arch Intern Med. 1999 Oct 11;159(18):2198-205. doi: 10.1001/archinte.159.18.2198.
- Reiff-Hekking S, Ockene JK, Hurley TG, Reed GW. Brief physician and nurse practitioner-delivered counseling for high-risk drinking. Results at 12-month follow-up. J Gen Intern Med. 2005 Jan;20(1):7-13. doi: 10.1111/j.1525-1497.2005.21240.x.
- McIntosh MC, Leigh G, Baldwin NJ, Marmulak J. Reducing alcohol consumption. Comparing three brief methods in family practice. Can Fam Physician. 1997 Nov;43:1959-62, 1965-7.
- Babor TF, Higgins-Biddle JC, Dauser D, Burleson JA, Zarkin GA, Bray J. Brief interventions for at-risk drinking: patient outcomes and cost-effectiveness in managed care organizations. Alcohol Alcohol. 2006 Nov-Dec;41(6):624-31. doi: 10.1093/alcalc/agl078. Epub 2006 Oct 10.
- Burke PJ, Da Silva JD, Vaughan BL, Knight JR. Training high school counselors on the use of motivational interviewing to screen for substance abuse. Subst Abus. 2005 Dec;26(3-4):31-4. doi: 10.1300/j465v26n03_07.
- Goodall CA, Ayoub AF, Crawford A, Smith I, Bowman A, Koppel D, Gilchrist G. Nurse-delivered brief interventions for hazardous drinkers with alcohol-related facial trauma: a prospective randomised controlled trial. Br J Oral Maxillofac Surg. 2008 Mar;46(2):96-101. doi: 10.1016/j.bjoms.2007.11.014. Epub 2007 Dec 21.
- Gil AG, Wagner EF, Tubman JG. Culturally sensitive substance abuse intervention for Hispanic and African American adolescents: empirical examples from the Alcohol Treatment Targeting Adolescents in Need (ATTAIN) Project. Addiction. 2004 Nov;99 Suppl 2:140-50. doi: 10.1111/j.1360-0443.2004.00861.x.
- Grenard JL, Ames SL, Wiers RW, Thush C, Stacy AW, Sussman S. Brief intervention for substance use among at-risk adolescents: a pilot study. J Adolesc Health. 2007 Feb;40(2):188-91. doi: 10.1016/j.jadohealth.2006.08.008. Epub 2006 Oct 27.
- Martin G, Copeland J, Swift W. The Adolescent Cannabis Check-Up: feasibility of a brief intervention for young cannabis users. J Subst Abuse Treat. 2005 Oct;29(3):207-13. doi: 10.1016/j.jsat.2005.06.005.
- Winters KC, Leitten W, Wagner E, O'Leary Tevyaw T. Use of brief interventions for drug abusing teenagers within a middle and high school setting. J Sch Health. 2007 Apr;77(4):196-206. doi: 10.1111/j.1746-1561.2007.00191.x.
- Srisurapanont M, Sombatmai S, Boripuntakul T. Brief intervention for students with methamphetamine use disorders: a randomized controlled trial. Am J Addict. 2007 Mar-Apr;16(2):111-6. doi: 10.1080/10550490601184431.
- Suzuki K, Takeda A, Murakami S, Yuzuriha T, Hiezima M, Yoshimori C, Fuzibayashi T. [Brief intervention for smoking, problem drinking and drug abuse by high school students]. Nihon Arukoru Yakubutsu Igakkai Zasshi. 2003 Dec;38(6):475-82. Japanese.
- Peterson PL, Baer JS, Wells EA, Ginzler JA, Garrett SB. Short-term effects of a brief motivational intervention to reduce alcohol and drug risk among homeless adolescents. Psychol Addict Behav. 2006 Sep;20(3):254-64. doi: 10.1037/0893-164X.20.3.254.
- McCambridge J, Strang J. The efficacy of single-session motivational interviewing in reducing drug consumption and perceptions of drug-related risk and harm among young people: results from a multi-site cluster randomized trial. Addiction. 2004 Jan;99(1):39-52. doi: 10.1111/j.1360-0443.2004.00564.x.
- Barroso T, Castanhola R, Marta M, et al. Effectiveness of brief alcohol interventions by clinical nurse specialists (CNS) in primary care settings. 2010 ISBRA World Congress, Paris, France, Sep 13-16, 2010
- National Institute on Alcohol Abuse and Alcoholism. Five-year strategic plan (FY07-11): Alcohol across the lifespan. Washington, DC: U.S. Department of Health and Human Services, 2006. http://pubs.niaaa.nih.gov/publications/StrategicPlan/NIAAASTRATEGICPLAN.htm. Accessed Oct 18, 2010.
- Institute of Medicine (US) Committee on Crossing the Quality Chasm: Adaptation to Mental Health and Addictive Disorders. Improving the Quality of Health Care for Mental and Substance-Use Conditions: Quality Chasm Series. Washington (DC): National Academies Press (US); 2006. Available from http://www.ncbi.nlm.nih.gov/books/NBK19830/
- Chambers RA, Taylor JR, Potenza MN. Developmental neurocircuitry of motivation in adolescence: a critical period of addiction vulnerability. Am J Psychiatry. 2003 Jun;160(6):1041-52. doi: 10.1176/appi.ajp.160.6.1041.
- Thatcher DL, Clark DB. Adolescents at risk for substance use disorders: role of psychological dysregulation, endophenotypes, and environmental influences. Alcohol Res Health. 2008;31(2):168-76.
- Di Forti M, Morrison PD, Butt A, Murray RM. Cannabis use and psychiatric and cogitive disorders: the chicken or the egg? Curr Opin Psychiatry. 2007 May;20(3):228-34. doi: 10.1097/YCO.0b013e3280fa838e.
- Ammon L, Sterling S, Mertens J, Weisner C. Adolescents in private chemical dependency programs: who are most at risk for HIV? J Subst Abuse Treat. 2005 Jul;29(1):39-45. doi: 10.1016/j.jsat.2005.03.003.
- Substance Abuse and Mental Health Services Administration. SAMHSA Report to Congress - Nov 2002. The prevention and treatment of co-occurring substance abuse disorders and mental disorders. Rockville, MD, 2002. http://www.samhsa.gov/reports/congress2002/CoOccurringRpt.pdf. Accessed Oct 25, 2010
- Brown SA, Tapert SF, Granholm E, Delis DC. Neurocognitive functioning of adolescents: effects of protracted alcohol use. Alcohol Clin Exp Res. 2000 Feb;24(2):164-71.
- Bava S, Tapert SF. Adolescent brain development and the risk for alcohol and other drug problems. Neuropsychol Rev. 2010 Dec;20(4):398-413. doi: 10.1007/s11065-010-9146-6. Epub 2010 Oct 19.
- Kaplan JE, Benson C, Holmes KK, Brooks JT, Pau A, Masur H; Centers for Disease Control and Prevention (CDC); National Institutes of Health; HIV Medicine Association of the Infectious Diseases Society of America. Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. MMWR Recomm Rep. 2009 Apr 10;58(RR-4):1-207; quiz CE1-4.
- Sisko AM, Truffer CJ, Keehan SP, Poisal JA, Clemens MK, Madison AJ. National health spending projections: the estimated impact of reform through 2019. Health Aff (Millwood). 2010 Oct;29(10):1933-41. doi: 10.1377/hlthaff.2010.0788. Epub 2010 Sep 9. Erratum In: Health Aff (Millwood). 2010 Nov;29(11):2128.
- Mental Health America. Parity and health care reform: important changes for behavioral health, 2010. http://www.mentalhealthamerica.net/go/action/policy-issues-a-z/healthcare-reform. Accessed Oct 21, 2010
- Curley B. Healthcare reform law gives big boost to addiction treatment and prevention. Join Together. Apr 9, 2010. http://www.jointogether.org/news/features/2010/healthcare-reform-law-gives.html. Accessed Oct 21, 2010
- Johnston LD, O'Malley PM, Bachman JG, et al. Cigarette smoking among American teens continues to decline, but more slowly than in the past [press release]. Ann Arbor, MI: University of Michigan News and Information Services, 2006. http://www.monitoringthefuture.org/pressreleases/06cigpr.pdf. Accessed Oct 20, 2010
- National Institute on Alcohol Abuse and Alcoholism. Statistical snapshot of underage drinking, 2008. http://www.niaaa.nih.gov/AboutNIAAA/NIAAASponsoredPrograms/StatisticalSnapshotUnderageDrinking.htm. Accessed Oct 19, 2010
- Johnston LD, O'Malley PM, Bachman JG, et al. Monitoring the Future national results on adolescent drug use: Overview of key findings 2004. Bethesda, MD: National Institute on Drug Abuse, 2005. http://www.drugabuse.gov/PDF/overview2004.pdf. Accessed Oct 19, 2009
- Knight JR, Harris SK, Sherritt L, Van Hook S, Lawrence N, Brooks T, Carey P, Kossack R, Kulig J. Prevalence of positive substance abuse screen results among adolescent primary care patients. Arch Pediatr Adolesc Med. 2007 Nov;161(11):1035-41. doi: 10.1001/archpedi.161.11.1035.
- Underage Drinking Enforcement Training Center. Welcome to the Underage Drinking Enforcement Training Center. http://www.udetc.org/index.asp. Updated Oct 2010. Accessed Oct 27, 2010
- Office of National Drug Control Policy. The economic costs of drug abuse in the United States, 1992-2002. Washington, DC: Executive Office of the President (Publication No. 207303), 2004
- Merenstein D, Green L, Fryer GE, Dovey S. Shortchanging adolescents: room for improvement in preventive care by physicians. Fam Med. 2001 Feb;33(2):120-3.
- Levy S, Vaughan BL, Knight JR. Office-based intervention for adolescent substance abuse. Pediatr Clin North Am. 2002 Apr;49(2):329-43. doi: 10.1016/s0031-3955(01)00007-4.
- Yoast RA, Fleming M, Balch GI. Reactions to a concept for physician intervention in adolescent alcohol use. J Adolesc Health. 2007 Jul;41(1):35-41. doi: 10.1016/j.jadohealth.2007.02.008. Epub 2007 May 3.
- Brown JD, Wissow LS. Discussion of sensitive health topics with youth during primary care visits: relationship to youth perceptions of care. J Adolesc Health. 2009 Jan;44(1):48-54. doi: 10.1016/j.jadohealth.2008.06.018. Epub 2008 Oct 25.
- Sterling S, Weisner C. The role of primary care in addressing adolescent substance use: Screening, treatment, and coordination. Paper presented at the
- Kaul P, Coupey SM. Clinical evaluation of substance abuse. Pediatr Rev. 2002 Mar;23(3):85-94. doi: 10.1542/pir.23-3-85. No abstract available.
- Knight JR. The role of the primary care provider in preventing and treating alcohol problems in adolescents. Ambul Pediatr. 2001 May-Jun;1(3):150-61. doi: 10.1367/1539-4409(2001)0012.0.co;2.
- Indications for management and referral of patients involved in substance abuse. American Academy of Pediatrics. Committee on Substance Abuse. Pediatrics. 2000 Jul;106(1 Pt 1):143-8. doi: 10.1542/peds.106.1.143.
- American Academy of Pediatrics. Committee on Substance Abuse. American Academy of Pediatrics. Committee on Substance Abuse. Tobacco, alcohol, and other drugs: the role of the pediatrician in prevention and management of substance abuse. Pediatrics. 1998 Jan;101(1 Pt 1):125-8.
- Guide to Clinical Preventive Services 2010 - 2011. AHRQ Publication No. 10-05145: Agency for Healthcare Research and Quality, 2010. http://www.ahrq.gov/clinic/pocketgd.htm. Accessed Oct 25, 2010
- American Academy of Pediatrics. Periodic survey of fellows: 45% of Fellows routinely screen for alcohol use., 2002. http://aapnews.aappublications.org/cgi/content/short/14/10/1. Accessed April 6, 2009
- Bethell C, Klein J, Peck C. Assessing health system provision of adolescent preventive services: the Young Adult Health Care Survey. Med Care. 2001 May;39(5):478-90. doi: 10.1097/00005650-200105000-00008.
- Friedman LS, Johnson B, Brett AS. Evaluation of substance-abusing adolescents by primary care physicians. J Adolesc Health Care. 1990 May;11(3):227-30. doi: 10.1016/0197-0070(90)90353-4.
- Wilson CR, Sherritt L, Gates E, Knight JR. Are clinical impressions of adolescent substance use accurate? Pediatrics. 2004 Nov;114(5):e536-40. doi: 10.1542/peds.2004-0098.
- Emans SJ, Bravender T, Knight J, Frazer C, Luoni M, Berkowitz C, Armstrong E, Goodman E. Adolescent medicine training in pediatric residency programs: are we doing a good job? Pediatrics. 1998 Sep;102(3 Pt 1):588-95. doi: 10.1542/peds.102.3.588.
- Leontieva L, Horn K, Haque A, Helmkamp J, Ehrlich P, Williams J. Readiness to change problematic drinking assessed in the emergency department as a predictor of change. J Crit Care. 2005 Sep;20(3):251-6. doi: 10.1016/j.jcrc.2005.05.009.
- Lawendowski LA. A motivational intervention for adolescent smokers. Prev Med. 1998 Sep-Oct;27(5 Pt 3):A39-46. doi: 10.1006/pmed.1998.0424.
- Knight JR, Sherritt L, Van Hook S, Gates EC, Levy S, Chang G. Motivational interviewing for adolescent substance use: a pilot study. J Adolesc Health. 2005 Aug;37(2):167-9. doi: 10.1016/j.jadohealth.2004.08.020.
- Marlatt GA, Baer JS, Kivlahan DR, Dimeff LA, Larimer ME, Quigley LA, Somers JM, Williams E. Screening and brief intervention for high-risk college student drinkers: results from a 2-year follow-up assessment. J Consult Clin Psychol. 1998 Aug;66(4):604-15. doi: 10.1037//0022-006x.66.4.604.
- Baer JS, Kivlahan DR, Blume AW, McKnight P, Marlatt GA. Brief intervention for heavy-drinking college students: 4-year follow-up and natural history. Am J Public Health. 2001 Aug;91(8):1310-6. doi: 10.2105/ajph.91.8.1310.
- Borsari B, Carey KB. Effects of a brief motivational intervention with college student drinkers. J Consult Clin Psychol. 2000 Aug;68(4):728-33.
- Carey KB, Correia CJ. Drinking motives predict alcohol-related problems in college students. J Stud Alcohol. 1997 Jan;58(1):100-5. doi: 10.15288/jsa.1997.58.100.
- Barnett NP, Monti PM, Wood MD. Motivational interviewing for alcohol-involved adolescents in the emergency room. . In: Wagner EF, Waldron HB, eds. Innovations in Adolescent Substance Abuse Interventions. Amsterdam, Netherlands: Pergamon/Elsevier Science Inc, 2001:143-168
- Larimer ME, Turner AP, Anderson BK, Fader JS, Kilmer JR, Palmer RS, Cronce JM. Evaluating a brief alcohol intervention with fraternities. J Stud Alcohol. 2001 May;62(3):370-80. doi: 10.15288/jsa.2001.62.370.
- Murphy JG, Duchnick JJ, Vuchinich RE, Davison JW, Karg RS, Olson AM, Smith AF, Coffey TT. Relative efficacy of a brief motivational intervention for college student drinkers. Psychol Addict Behav. 2001 Dec;15(4):373-9. doi: 10.1037//0893-164x.15.4.373.
- Spirito A, Monti PM, Barnett NP, Colby SM, Sindelar H, Rohsenow DJ, Lewander W, Myers M. A randomized clinical trial of a brief motivational intervention for alcohol-positive adolescents treated in an emergency department. J Pediatr. 2004 Sep;145(3):396-402. doi: 10.1016/j.jpeds.2004.04.057.
- Monti PM, Colby SM, Barnett NP, Spirito A, Rohsenow DJ, Myers M, Woolard R, Lewander W. Brief intervention for harm reduction with alcohol-positive older adolescents in a hospital emergency department. J Consult Clin Psychol. 1999 Dec;67(6):989-94. doi: 10.1037//0022-006x.67.6.989.
- Tait RJ, Hulse GK, Robertson SI, Sprivulis PC. Emergency department-based intervention with adolescent substance users: 12-month outcomes. Drug Alcohol Depend. 2005 Sep 1;79(3):359-63. doi: 10.1016/j.drugalcdep.2005.03.015. Epub 2005 Apr 26.
- D'Amico EJ, Miles JN, Stern SA, Meredith LS. Brief motivational interviewing for teens at risk of substance use consequences: a randomized pilot study in a primary care clinic. J Subst Abuse Treat. 2008 Jul;35(1):53-61. doi: 10.1016/j.jsat.2007.08.008. Epub 2007 Nov 26.
- Gates S, McCambridge J, Smith LA, Foxcroft DR. Interventions for prevention of drug use by young people delivered in non-school settings. Cochrane Database Syst Rev. 2006 Jan 25;(1):CD005030. doi: 10.1002/14651858.CD005030.pub2.
- Ozer EM, Adams SH, Lustig JL, Millstein SG, Camfield K, El-Diwany S, Volpe S, Irwin CE Jr. Can it be done? Implementing adolescent clinical preventive services. Health Serv Res. 2001 Dec;36(6 Pt 2):150-65.
- Bien TH, Miller WR, Tonigan JS. Brief interventions for alcohol problems: a review. Addiction. 1993 Mar;88(3):315-35. doi: 10.1111/j.1360-0443.1993.tb00820.x.
- D'Onofrio G, Degutis LC. Preventive care in the emergency department: screening and brief intervention for alcohol problems in the emergency department: a systematic review. Acad Emerg Med. 2002 Jun;9(6):627-38. doi: 10.1111/j.1553-2712.2002.tb02304.x.
- Kanouse DE, Kallich JD, Kahan JP. Dissemination of effectiveness and outcomes research. Health Policy. 1995 Dec;34(3):167-92. doi: 10.1016/0168-8510(95)00760-1.
- Bertholet N, Daeppen JB, Wietlisbach V, Fleming M, Burnand B. Reduction of alcohol consumption by brief alcohol intervention in primary care: systematic review and meta-analysis. Arch Intern Med. 2005 May 9;165(9):986-95. doi: 10.1001/archinte.165.9.986.
- Kaner E, Bland M, Cassidy P, et al. Screening and brief alcohol intervention in routine primary care In the UK: SIPS trial outcomes at six months. 2010 ISBRA World Congress, Paris, France, Sep 13-16, 2010
- Clark DB, Gordon AJ, Ettaro LR, Owens JM, Moss HB. Screening and brief intervention for underage drinkers. Mayo Clin Proc. 2010 Apr;85(4):380-91. doi: 10.4065/mcp.2008.0638.
- Friedmann PD, McCullough D, Saitz R. Screening and intervention for illicit drug abuse: a national survey of primary care physicians and psychiatrists. Arch Intern Med. 2001 Jan 22;161(2):248-51. doi: 10.1001/archinte.161.2.248.
- Ewing GB, Selassie AW, Lopez CH, McCutcheon EP. Self-report of delivery of clinical preventive services by U.S. physicians. Comparing specialty, gender, age, setting of practice, and area of practice. Am J Prev Med. 1999 Jul;17(1):62-72. doi: 10.1016/s0749-3797(99)00032-x.
- Klein JD, Wilson KM. Delivering quality care: adolescents' discussion of health risks with their providers. J Adolesc Health. 2002 Mar;30(3):190-5. doi: 10.1016/s1054-139x(01)00342-1.
- Mertens JR, Flisher AJ, Fleming MF, Weisner CM. Medical conditions of adolescents in alcohol and drug treatment: comparison with matched controls. J Adolesc Health. 2007 Feb;40(2):173-9. doi: 10.1016/j.jadohealth.2006.09.021. Epub 2006 Nov 29.
- Sterling S, Kohn C, Lu Y, Weisner C. Pathways to chemical dependency treatment for adolescents in an HMO. J Psychoactive Drugs. 2004 Dec;36(4):439-53. doi: 10.1080/02791072.2004.10524427.
- Saitz R, Svikis D, D'Onofrio G, Kraemer KL, Perl H. Challenges applying alcohol brief intervention in diverse practice settings: populations, outcomes, and costs. Alcohol Clin Exp Res. 2006 Feb;30(2):332-8. doi: 10.1111/j.1530-0277.2006.00038.x.
- Massachusetts Department of Public Health Bureau of Substance Abuse Services. Provider Guide: Adolescent Screening, Brief Intervention, and Referral to Treatment Using the CRAFFT Screening Tool. Boston: Massachusetts Department of Public Health, 2009
- Phillips JL, Smithstan P. Brief intervention: An approach for substance abusing adolescents. Trainer and trainee guide. A CARS training program prepared by Joel L. Phillips and Pam Smithstan, MFT, based on the work of Ken Winters, PhD. Santa Rosa, CA: Center for Applied Research Solutions, 2006. http://indianeducation.org/userfiles/file/Session%207_3b%20Brief%20Intervention%20FBecker.pdf
- Barry KL, Blow FC, Willenbring ML, McCormick R, Brockmann LM, Visnic S. Use of Alcohol Screening and Brief Interventions<br />in Primary Care Settings:Implementation and Barriers. Subst Abus. 2004 Mar;25(1):27-36. doi: 10.1300/J465v25n01_05.
- Friedmann PD, McCullough D, Chin MH, Saitz R. Screening and intervention for alcohol problems. A national survey of primary care physicians and psychiatrists. J Gen Intern Med. 2000 Feb;15(2):84-91. doi: 10.1046/j.1525-1497.2000.03379.x.
- Spandorfer JM, Israel Y, Turner BJ. Primary care physicians' views on screening and management of alcohol abuse: inconsistencies with national guidelines. J Fam Pract. 1999 Nov;48(11):899-902.
- Gottlieb NH, Mullen PD, McAlister AL. Patients' substance abuse and the primary care physician: patterns of practice. Addict Behav. 1987;12(1):23-32. doi: 10.1016/0306-4603(87)90005-0.
- Miller NS, Sheppard LM, Colenda CC, Magen J. Why physicians are unprepared to treat patients who have alcohol- and drug-related disorders. Acad Med. 2001 May;76(5):410-8. doi: 10.1097/00001888-200105000-00007.
- Ogborne AC, Rush B, Ekdahl A, Fondacaro R. The views of health and social service professionals regarding alcohol problems and their treatment. Int J Addict. 1986 Sep-Oct;21(9-10):1051-8. doi: 10.3109/10826088609077254.
- Ozer EM, Adams SH, Gardner LR, Mailloux DE, Wibbelsman CJ, Irwin CE Jr. Provider self-efficacy and the screening of adolescents for risky health behaviors. J Adolesc Health. 2004 Aug;35(2):101-7. doi: 10.1016/j.jadohealth.2003.09.016.
- Saitz R, Friedmann PD, Sullivan LM, Winter MR, Lloyd-Travaglini C, Moskowitz MA, Samet JH. Professional satisfaction experienced when caring for substance-abusing patients: faculty and resident physician perspectives. J Gen Intern Med. 2002 May;17(5):373-6. doi: 10.1046/j.1525-1497.2002.10520.x.
- Westermeyer J, Doheny S, Stone B. An assessment of hospital care for the alcoholic patient. Alcohol Clin Exp Res. 1978 Jan;2(1):53-7. doi: 10.1111/j.1530-0277.1978.tb04694.x.
- Gardner W, Pajer KA, Kelleher KJ, Scholle SH, Wasserman RC. Child sex differences in primary care clinicians' mental health care of children and adolescents. Arch Pediatr Adolesc Med. 2002 May;156(5):454-9. doi: 10.1001/archpedi.156.5.454.
- Gardner W, Kelleher KJ, Pajer KA, Campo JV. Primary care clinicians' use of standardized tools to assess child psychosocial problems. Ambul Pediatr. 2003 Jul-Aug;3(4):191-5. doi: 10.1367/1539-4409(2003)0032.0.co;2.
- Volk RJ, Steinbauer JR, Cantor SB. Patient factors influencing variation in the use of preventive interventions for alcohol abuse by primary care physicians. J Stud Alcohol. 1996 Mar;57(2):203-9. doi: 10.15288/jsa.1996.57.203.
- McCrady BS, Richter SS, Morgan TJ, Slade J, Pfeifer C. Involving health care workers in screening for alcohol problems. J Addict Dis. 1996;15(3):45-58. doi: 10.1300/J069v15n03_03.
- Franzgrote M, Ellen JM, Millstein SG, Irwin CE Jr. Screening for adolescent smoking among primary care physicians in California. Am J Public Health. 1997 Aug;87(8):1341-5. doi: 10.2105/ajph.87.8.1341.
- Ellen JM, Franzgrote M, Irwin CE Jr, Millstein SG. Primary care physicians' screening of adolescent patients: a survey of California physicians. J Adolesc Health. 1998 Jun;22(6):433-8. doi: 10.1016/s1054-139x(97)00276-0.
- Barnett NP, Monti PM, Cherpitel C, Bendtsen P, Borges G, Colby SM, Nordqvist C, Johansson K. Identification and brief treatment of alcohol problems with medical patients: an international perspective. Alcohol Clin Exp Res. 2003 Feb;27(2):262-70. doi: 10.1097/01.ALC.0000057123.36127.8B.
- Sterling S, Weisner C, Hinman A, Parthasarathy S. Access to treatment for adolescents with substance use and co-occurring disorders: challenges and opportunities. J Am Acad Child Adolesc Psychiatry. 2010 Jul;49(7):637-46; quiz 725-6. doi: 10.1016/j.jaac.2010.03.019. Epub 2010 May 8.
- Parthasarathy S, Weisner C. Health care services use by adolescents with intakes into an outpatient alcohol and drug treatment program. Am J Addict. 2006;15 Suppl 1:113-21. doi: 10.1080/10550490601006097.
- Sterling S, Weisner C. Chemical dependency and psychiatric services for adolescents in private managed care: implications for outcomes. Alcohol Clin Exp Res. 2005 May;29(5):801-9. doi: 10.1097/01.alc.0000164373.89061.2c. Erratum In: Alcohol Clin Exp Res. 2005 Oct;29(10):1914.
- Sterling S, Weisner C. Translating research findings into practice: example of treatment services for adolescents in managed care. Alcohol Res Health. 2006;29(1):11-8.
- Sterling S, Chi F, Campbell C, Weisner C. Three-year chemical dependency and mental health treatment outcomes among adolescents: the role of continuing care. Alcohol Clin Exp Res. 2009 Aug;33(8):1417-29. doi: 10.1111/j.1530-0277.2009.00972.x. Epub 2009 Apr 30.
- Wu NS, Lu Y, Sterling S, Weisner C. Family environment factors and substance abuse severity in an HMO adolescent treatment population. Clin Pediatr (Phila). 2004 May;43(4):323-33. doi: 10.1177/000992280404300403.
- Campbell CI, Chi F, Sterling S, Kohn C, Weisner C. Self-initiated tobacco cessation and substance use outcomes among adolescents entering substance use treatment in a managed care organization. Addict Behav. 2009 Feb;34(2):171-9. doi: 10.1016/j.addbeh.2008.10.002. Epub 2008 Oct 10.
- Chi FW, Sterling S, Campbell CI, et al. Twelve-step participation at 5-year follow-up among a diverse sample of adolescents entering chemical dependency treatment. Joint Meeting on Adolescent Treatment Effectiveness (JMATE), Washington, DC, Mar 25-27, 2008
- Scott M, Parthasarathy S, Kohn C, Hinman A, Sterling S, Weisner C. Adolescents with substance diagnoses in an HMO: factors associated with medical provider referrals to substance abuse and mental health treatment. Ment Health Serv Res. 2004 Mar;6(1):47-60. doi: 10.1023/b:mhsr.0000011256.70502.ed.
- Chi FW, Sterling S, Weisner C. Adolescents with co-occurring substance use and mental conditions in a private managed care health plan: prevalence, patient characteristics, and treatment initiation and engagement. Am J Addict. 2006;15 Suppl 1:67-79. doi: 10.1080/10550490601006022.
- Mertens JR, Weisner C, Ray GT, Fireman B, Walsh K. Hazardous drinkers and drug users in HMO primary care: prevalence, medical conditions, and costs. Alcohol Clin Exp Res. 2005 Jun;29(6):989-98. doi: 10.1097/01.alc.0000167958.68586.3d.
- Mertens JR, Lu YW, Parthasarathy S, Moore C, Weisner CM. Medical and psychiatric conditions of alcohol and drug treatment patients in an HMO: comparison with matched controls. Arch Intern Med. 2003 Nov 10;163(20):2511-7. doi: 10.1001/archinte.163.20.2511.
- Weisner C, Mertens J, Parthasarathy S, Moore C, Lu Y. Integrating primary medical care with addiction treatment: a randomized controlled trial. JAMA. 2001 Oct 10;286(14):1715-23. doi: 10.1001/jama.286.14.1715.
- Chi FW, Weisner CM. Nine-year psychiatric trajectories and substance use outcomes: an application of the group-based modeling approach. Eval Rev. 2008 Feb;32(1):39-58. doi: 10.1177/0193841X07307317.
- Parthasarathy S, Weisner C, Hu TW, Moore C. Association of outpatient alcohol and drug treatment with health care utilization and cost: revisiting the offset hypothesis. J Stud Alcohol. 2001 Jan;62(1):89-97. doi: 10.15288/jsa.2001.62.89.
- Parthasarathy S, Weisner CM. Five-year trajectories of health care utilization and cost in a drug and alcohol treatment sample. Drug Alcohol Depend. 2005 Nov 1;80(2):231-40. doi: 10.1016/j.drugalcdep.2005.04.004.
- Alexandre PK, French MT, Matzger H, Weisner C. Addiction treatment history, medical services utilization, and cost: a longitudinal analysis of problem drinkers. J Addict Dis. 2006;25(1):105-20. doi: 10.1300/J069v25n01_13.
- Van Den Eeden SK, Tanner CM, Bernstein AL, Fross RD, Leimpeter A, Bloch DA, Nelson LM. Incidence of Parkinson's disease: variation by age, gender, and race/ethnicity. Am J Epidemiol. 2003 Jun 1;157(11):1015-22. doi: 10.1093/aje/kwg068.
- Knight JR, Sherritt L, Harris SK, Gates EC, Chang G. Validity of brief alcohol screening tests among adolescents: a comparison of the AUDIT, POSIT, CAGE, and CRAFFT. Alcohol Clin Exp Res. 2003 Jan;27(1):67-73. doi: 10.1097/01.ALC.0000046598.59317.3A.
- Wibbelsman CJ. Confidentiality in an Age of Managed Care: Can It Exist? Adolesc Med. 1997 Oct;8(3):427-432.
- Desy PM, Perhats C. Alcohol screening, brief intervention, and referral in the emergency department: an implementation study. J Emerg Nurs. 2008 Feb;34(1):11-9. doi: 10.1016/j.jen.2007.03.019. Epub 2007 Dec 3.
- Fleming MF. Strategies to increase alcohol screening in health care settings. Alcohol Health Res World. 1997;21(4):340-7.
- Miller WR, Rollnick S. Motivational Interviewing: Preparing People for Change. 2nd ed. New York: Guilford Press, 2002
- Moyers TB, Martin T, Manuel JK, Hendrickson SM, Miller WR. Assessing competence in the use of motivational interviewing. J Subst Abuse Treat. 2005 Jan;28(1):19-26. doi: 10.1016/j.jsat.2004.11.001.
- Hunkeler EM, Meresman JF, Hargreaves WA, Fireman B, Berman WH, Kirsch AJ, Groebe J, Hurt SW, Braden P, Getzell M, Feigenbaum PA, Peng T, Salzer M. Efficacy of nurse telehealth care and peer support in augmenting treatment of depression in primary care. Arch Fam Med. 2000 Aug;9(8):700-8. doi: 10.1001/archfami.9.8.700.
- Meresman JF, Hunkeler EM, Hargreaves WA, Kirsch AJ, Robinson P, Green A, Mann EZ, Getzell M, Feigenbaum P. A case report: implementing a nurse telecare program for treating depression in primary care. Psychiatr Q. 2003 Spring;74(1):61-73. doi: 10.1023/a:1021145722959.
- Fraser D. The depression initiative: an alliance to improve treatment. The Permanente Journal. 1998;2 (3):5-11
- Aspy CB, Mold JW, Thompson DM, Blondell RD, Landers PS, Reilly KE, Wright-Eakers L. Integrating screening and interventions for unhealthy behaviors into primary care practices. Am J Prev Med. 2008 Nov;35(5 Suppl):S373-80. doi: 10.1016/j.amepre.2008.08.015.
- Leffingwell TR. Motivational Interviewing Knowledge and Attitudes Test (MIKAT) for evaluation of training outcomes. Minuet. 2006;13 (1):10-11
- Meyers K, McLellan AT, Jaeger JL, Pettinati HM. The development of the Comprehensive Addiction Severity Index for Adolescents (CASI-A). An interview for assessing multiple problems of adolescents. J Subst Abuse Treat. 1995 May-Jun;12(3):181-93. doi: 10.1016/0740-5472(95)00009-t.
- Whitmore EA, Mikulich SK, Thompson LL, Riggs PD, Aarons GA, Crowley TJ. Influences on adolescent substance dependence: conduct disorder, depression, attention deficit hyperactivity disorder, and gender. Drug Alcohol Depend. 1997 Aug 25;47(2):87-97. doi: 10.1016/s0376-8716(97)00074-4.
- Ammon L, Lu Y, Weisner C. Adolescents in substance abuse treatment: Are they at risk for HIV? 131st meeting of American Public Health Association, San Francisco, CA, 2003
- Balsa AI, Homer JF, French MT, Weisner CM. Substance use, education, employment, and criminal activity outcomes of adolescents in outpatient chemical dependency programs. J Behav Health Serv Res. 2009 Jan;36(1):75-95. doi: 10.1007/s11414-007-9095-x. Epub 2007 Dec 7.
- Weisner C, Mertens J, Parthasarathy S, Moore C, Hunkeler EM, Hu T, Selby JV. The outcome and cost of alcohol and drug treatment in an HMO: day hospital versus traditional outpatient regimens. Health Serv Res. 2000 Oct;35(4):791-812.
- Parthasarathy S, Mertens J, Moore C, Weisner C. Utilization and cost impact of integrating substance abuse treatment and primary care. Med Care. 2003 Mar;41(3):357-67. doi: 10.1097/01.MLR.0000053018.20700.56.
- Hsiao C. Analysis of Panel Data. New York: Cambridge University Press, 1986
- Muthén B, Kaplan D, Hollis M. On structural equation modeling with data that are not missing completely at random. Psychometrika. 1987;42:431-462
- Sterling S, Weisner C. Improving retention among women in substance abuse treatment: Is childcare enough? 129th meeting of the American Public Health Association, Atlanta, GA, 2001
- Qualitative Solutions and Research: QSR NUD*IST [computer program]. 5.0. Thousand Oaks, CA: Sage Publications; 2000
- Cohen J. Statistical Power Analysis for the Behavioral Sciences. Hillsdale, NJ: Lawrence Erlbaum Associates, Inc., 1988
- de Leeuw J, Kreft IG. Questioning multilevel models. J Educ Behav Stat. 1995;20 (2):171-189
- Bryk AS, Raudenbush SW. Hierarchical Linear Models: Applications and Data Analysis Methods. Newbury Park: Sage, 1992
- Barrientos-Gutierrez T, Gimeno D, Mangione TW, Harrist RB, Amick BC. Drinking social norms and drinking behaviours: a multilevel analysis of 137 workgroups in 16 worksites. Occup Environ Med. 2007 Sep;64(9):602-8. doi: 10.1136/oem.2006.031765. Epub 2007 May 24.
- Cosby RH, Howard M, Kaczorowski J, Willan AR, Sellors JW. Randomizing patients by family practice: sample size estimation, intracluster correlation and data analysis. Fam Pract. 2003 Feb;20(1):77-82. doi: 10.1093/fampra/20.1.77.
- Slymen DJ, Hovell MF. Cluster versus individual randomization in adolescent tobacco and alcohol studies: illustrations for design decisions. Int J Epidemiol. 1997 Aug;26(4):765-71. doi: 10.1093/ije/26.4.765.
- Mertens JR, Flisher AJ, Satre DD, Weisner CM. The role of medical conditions and primary care services in 5-year substance use outcomes among chemical dependency treatment patients. Drug Alcohol Depend. 2008 Nov 1;98(1-2):45-53. doi: 10.1016/j.drugalcdep.2008.04.007. Epub 2008 Jun 20.
- Mertens JR, Weisner CM. Predictors of substance abuse treatment retention among women and men in an HMO. Alcohol Clin Exp Res. 2000 Oct;24(10):1525-33.
- Weisner C, Delucchi K, Matzger H, Schmidt L. The role of community services and informal support on five-year drinking trajectories of alcohol dependent and problem drinkers. J Stud Alcohol. 2003 Nov;64(6):862-73. doi: 10.15288/jsa.2003.64.862.
- Weisner C, Matzger H. Missed opportunities in addressing drinking behavior in medical and mental health services. Alcohol Clin Exp Res. 2003 Jul;27(7):1132-41. doi: 10.1097/01.ALC.0000075546.38349.69.
- Weisner C, Schmidt LA. Rethinking access to alcohol treatment. Recent Dev Alcohol. 2001;15:107-36. doi: 10.1007/978-0-306-47193-3_7. No abstract available.
- Sterling S, Parthasarathy S, Jones A, Weisner C, Metz V, Hartman L, Saba K, Kline-Simon AH. Young Adult Substance Use and Healthcare Use Associated With Screening, Brief Intervention and Referral to Treatment in Pediatric Primary Care. J Adolesc Health. 2022 Oct;71(4S):S15-S23. doi: 10.1016/j.jadohealth.2021.11.033.
- Parthasarathy S, Kline-Simon AH, Jones A, Hartman L, Saba K, Weisner C, Sterling S. Three-Year Outcomes After Brief Treatment of Substance Use and Mood Symptoms. Pediatrics. 2021 Jan;147(1):e2020009191. doi: 10.1542/peds.2020-009191.
- Sterling S, Kline-Simon AH, Weisner C, Jones A, Satre DD. Pediatrician and Behavioral Clinician-Delivered Screening, Brief Intervention and Referral to Treatment: Substance Use and Depression Outcomes. J Adolesc Health. 2018 Apr;62(4):390-396. doi: 10.1016/j.jadohealth.2017.10.016. Epub 2018 Feb 1.
- Sterling S, Kline-Simon AH, Jones A, Satre DD, Parthasarathy S, Weisner C. Specialty addiction and psychiatry treatment initiation and engagement: Results from an SBIRT randomized trial in pediatrics. J Subst Abuse Treat. 2017 Nov;82:48-54. doi: 10.1016/j.jsat.2017.09.005. Epub 2017 Sep 10.
- Sterling S, Kline-Simon AH, Satre DD, Jones A, Mertens J, Wong A, Weisner C. Implementation of Screening, Brief Intervention, and Referral to Treatment for Adolescents in Pediatric Primary Care: A Cluster Randomized Trial. JAMA Pediatr. 2015 Nov;169(11):e153145. doi: 10.1001/jamapediatrics.2015.3145. Epub 2015 Nov 2.
- Elster A. The American Medical Association Guidelines for Adolescent Preventive Services. Arch Pediatr Adolesc Med. 1997 Sep;151(9):958-9. doi: 10.1001/archpedi.1997.02170460096021. No abstract available.
Studie record data
Deze datums volgen de voortgang van het onderzoeksdossier en de samenvatting van de ingediende resultaten bij ClinicalTrials.gov. Studieverslagen en gerapporteerde resultaten worden beoordeeld door de National Library of Medicine (NLM) om er zeker van te zijn dat ze voldoen aan specifieke kwaliteitscontrolenormen voordat ze op de openbare website worden geplaatst.
Bestudeer belangrijke data
Studie start (Werkelijk)
1 oktober 2011
Primaire voltooiing (Werkelijk)
1 oktober 2013
Studie voltooiing (Geschat)
31 december 2025
Studieregistratiedata
Eerst ingediend
20 maart 2015
Eerst ingediend dat voldeed aan de QC-criteria
31 maart 2015
Eerst geplaatst (Geschat)
6 april 2015
Updates van studierecords
Laatste update geplaatst (Werkelijk)
18 juli 2023
Laatste update ingediend die voldeed aan QC-criteria
14 juli 2023
Laatst geverifieerd
1 juli 2023
Meer informatie
Termen gerelateerd aan deze studie
Aanvullende relevante MeSH-voorwaarden
Andere studie-ID-nummers
- 11-07796
Informatie over medicijnen en apparaten, studiedocumenten
Bestudeert een door de Amerikaanse FDA gereguleerd geneesmiddel
Nee
Bestudeert een door de Amerikaanse FDA gereguleerd apparaatproduct
Nee
Deze informatie is zonder wijzigingen rechtstreeks van de website clinicaltrials.gov gehaald. Als u verzoeken heeft om uw onderzoeksgegevens te wijzigen, te verwijderen of bij te werken, neem dan contact op met register@clinicaltrials.gov. Zodra er een wijziging wordt doorgevoerd op clinicaltrials.gov, wordt deze ook automatisch bijgewerkt op onze website .
Klinische onderzoeken op Stofgerelateerde aandoeningen
-
University of HoustonOnbekend
-
UCB Biopharma SRLNog niet aan het wervenOntwikkelings- en epileptische encefalopathieën | SLC6A1 Neurodevelopmental Disorder (NDD)
-
New York City Health and Hospitals CorporationBeëindigdGlaucoom | Ziekte van het netvlies | Visuele Pathway DisorderVerenigde Staten
-
Neuro-Eye Diagnostic Systems, LLCNeuro-ophthalmology of Texas PLLCAanmelden op uitnodigingMacula ziekte | Visuele Pathway Disorder | Ziekte van de oogzenuwVerenigde Staten
-
Otsuka Pharmaceutical Co., Ltd.WervingAttention-deficit Hyperactivity Disorder (ADHD)Japan
-
Assistance Publique - Hôpitaux de ParisNog niet aan het wervenMajor Depressive Disorder (MDD) met slapeloosheidFrankrijk
-
Otsuka Pharmaceutical Co., Ltd.WervingAttention-deficit Hyperactivity Disorder (ADHD)Japan
-
Fondazione G.B. Bietti, IRCCSVoltooidGlaucoom | Optische neuropathie, ischemische | Optische zenuw | Visuele Pathway Disorder | Neurale geleidingItalië
-
University of MiamiNational Eye Institute (NEI)VoltooidGlaucoom | Maculaire degeneratie | Retinale degeneratie | Optische neuropathie | DrDeramus verdachte | Visuele Pathway DisorderVerenigde Staten
-
Isfahan University of Medical SciencesVoltooidZiekte van Tanger | Body Mass Index Quantitative Trait Locus 5 DisorderIran, Islamitische Republiek
Klinische onderzoeken op Huisarts in de eerste lijn
-
Thomas Jefferson UniversityRita & Alex Hillman FoundationVoltooidChronische obstructieve longziekteVerenigde Staten
-
Yale UniversityNational Institute on Drug Abuse (NIDA)Voltooid
-
Thomas Jefferson UniversityIndependence Blue CrossVoltooidZiekte van Alzheimer | Frontotemporale degeneratie | Vasculaire dementie | Dementie van het Alzheimer-type | Lewy Body dementie | Gemengde dementie | Vasculaire cognitieve stoornissenVerenigde Staten
-
International Centre for Diarrhoeal Disease Research...VoltooidGeestelijke stoornisBangladesh
-
University of Colorado, DenverSan Diego State University; University of Kansas Medical CenterWervingHPV-infectie | Preventieve gezondheidsdienstenVerenigde Staten
-
University of TorontoActief, niet wervendDiabetes mellitus | EenzaamheidCanada
-
San Francisco Veterans Affairs Medical CenterNational Center for Complementary and Integrative Health (NCCIH)Voltooid
-
University of OklahomaNational Institute on Alcohol Abuse and Alcoholism (NIAAA); Fogarty International... en andere medewerkersVoltooidFoetale alcoholspectrumstoornissen | Foetaal Alcohol Syndroom (FAS) | Alcoholmisbruik tijdens de zwangerschapRussische Federatie
-
The University of Texas Health Science Center,...National Institute on Aging (NIA)WervingOuderen mishandeling | Ouderen mishandelingVerenigde Staten
-
SingHealth PolyclinicsAISG Health Grand ChallengeActief, niet wervendDiabetes mellitus, type 2Singapore