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A Trial Comparing Cardiovascular Safety of Insulin Degludec Versus Insulin Glargine in Subjects With Type 2 Diabetes at High Risk of Cardiovascular Events (DEVOTE)

10. juli 2019 opdateret af: Novo Nordisk A/S

This trial is conducted globally. The aim of this trial is to compare cardiovascular safety of insulin degludec versus insulin glargine in subjects with type 2 diabetes at high risk of cardiovascular events.

Studieoversigt

Status

Afsluttet

Betingelser

Intervention / Behandling

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

7637

Fase

Fase 3

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Algeriet
- - Algiers, Algeriet, 16000
    - Novo Nordisk Investigational Site
  - Constantine, Algeriet, 25000
    - Novo Nordisk Investigational Site
  - Oran, Algeriet, 31000
    - Novo Nordisk Investigational Site
  - Sidi Bel Abbes, Algeriet, 22000
    - Novo Nordisk Investigational Site
Argentina
- - Caba, Argentina, C1440AAD
    - Novo Nordisk Investigational Site
  - Cordoba, Argentina, 5000
    - Novo Nordisk Investigational Site
  - Mar del Plata, Argentina, B7600FZN
    - Novo Nordisk Investigational Site
  - Rosario, Argentina, S2000CUD
    - Novo Nordisk Investigational Site
  - Zarate, Argentina, B2800DGH
    - Novo Nordisk Investigational Site
Brasilien
- - Fortaleza, Brasilien, 60430-350
    - Novo Nordisk Investigational Site
  - Porto Alegre, Brasilien, 90035-170
    - Novo Nordisk Investigational Site
- Ceara
  - Fortaleza, Ceara, Brasilien, 60115-282
    - Novo Nordisk Investigational Site
- Distrito Federal
  - Brasília, Distrito Federal, Brasilien, 71625-009
    - Novo Nordisk Investigational Site
- Goias
  - Aparecida de Goiania, Goias, Brasilien, 74935-530
    - Novo Nordisk Investigational Site
- Para
  - Belém, Para, Brasilien, 66073-000
    - Novo Nordisk Investigational Site
- Sao Paulo
  - Mogi das Cruzes, Sao Paulo, Brasilien, 08780-090
    - Novo Nordisk Investigational Site
  - São Paulo, Sao Paulo, Brasilien, 05403-000
    - Novo Nordisk Investigational Site
  - São Paulo, Sao Paulo, Brasilien, 01223-001
    - Novo Nordisk Investigational Site
  - São Paulo, Sao Paulo, Brasilien, 01228-000
    - Novo Nordisk Investigational Site
  - São Paulo, Sao Paulo, Brasilien, 01228-200
    - Novo Nordisk Investigational Site
Canada
- Alberta
  - Edmonton, Alberta, Canada, T5J 3N4
    - Novo Nordisk Investigational Site
- Manitoba
  - Winnipeg, Manitoba, Canada, R3E 3P4
    - Novo Nordisk Investigational Site
- Ontario
  - Chatham, Ontario, Canada, N7L 1C1
    - Novo Nordisk Investigational Site
  - Ottawa, Ontario, Canada, K1K 4L2
    - Novo Nordisk Investigational Site
  - Sarnia, Ontario, Canada, N7T 4X3
    - Novo Nordisk Investigational Site
- Quebec
  - Laval, Quebec, Canada, H7T 2P5
    - Novo Nordisk Investigational Site
Den Russiske Føderation
- - Ekaterinburg, Den Russiske Føderation, 620102
    - Novo Nordisk Investigational Site
  - Kemerovo, Den Russiske Føderation, 650002
    - Novo Nordisk Investigational Site
  - Kirov, Den Russiske Føderation, 610014
    - Novo Nordisk Investigational Site
  - Krasnodar, Den Russiske Føderation, 350012
    - Novo Nordisk Investigational Site
  - Krasnodar, Den Russiske Føderation, 350086
    - Novo Nordisk Investigational Site
  - Moscow, Den Russiske Føderation, 123423
    - Novo Nordisk Investigational Site
  - Moscow, Den Russiske Føderation, 111539
    - Novo Nordisk Investigational Site
  - Nizhny Novgorod, Den Russiske Føderation, 603018
    - Novo Nordisk Investigational Site
  - Rostov-on-Don, Den Russiske Føderation, 344068
    - Novo Nordisk Investigational Site
  - Saint-Petersburg, Den Russiske Føderation, 194356
    - Novo Nordisk Investigational Site
  - Saint-Petersburg, Den Russiske Føderation, 195213
    - Novo Nordisk Investigational Site
  - Saint-Petersburg, Den Russiske Føderation, 191119
    - Novo Nordisk Investigational Site
  - Saratov, Den Russiske Føderation, 410053
    - Novo Nordisk Investigational Site
  - Saratov, Den Russiske Føderation, 410031
    - Novo Nordisk Investigational Site
  - St. Petersburg, Den Russiske Føderation, 194354
    - Novo Nordisk Investigational Site
  - St. Petersburg, Den Russiske Føderation, 196084
    - Novo Nordisk Investigational Site
  - Syktyvkar, Den Russiske Føderation, 167981
    - Novo Nordisk Investigational Site
  - Tumen, Den Russiske Føderation, 625023
    - Novo Nordisk Investigational Site
  - Tver, Den Russiske Føderation, 170036
    - Novo Nordisk Investigational Site
  - Ulianovsk, Den Russiske Føderation, 432063
    - Novo Nordisk Investigational Site
  - Volgograd, Den Russiske Føderation, 400131
    - Novo Nordisk Investigational Site
  - Yaroslavl, Den Russiske Føderation, 150010
    - Novo Nordisk Investigational Site
Det Forenede Kongerige
- - Bristol, Det Forenede Kongerige, BS10 5NB
    - Novo Nordisk Investigational Site
  - Dundee, Det Forenede Kongerige, DD1 9SY
    - Novo Nordisk Investigational Site
  - Edinburgh, Det Forenede Kongerige, EH4 2XU
    - Novo Nordisk Investigational Site
  - Guildford, Det Forenede Kongerige, GU2 7XX
    - Novo Nordisk Investigational Site
  - Norwich, Det Forenede Kongerige, NR4 7TJ
    - Novo Nordisk Investigational Site
  - Nuneaton, Det Forenede Kongerige, CV10 7DJ
    - Novo Nordisk Investigational Site
  - Stevenage, Det Forenede Kongerige, SG1 4AB
    - Novo Nordisk Investigational Site
  - Wolverhampton, Det Forenede Kongerige, WV10 0QP
    - Novo Nordisk Investigational Site
Forenede Stater
- Alabama
  - Birmingham, Alabama, Forenede Stater, 35294
    - Novo Nordisk Investigational Site
  - Birmingham, Alabama, Forenede Stater, 35216
    - Novo Nordisk Investigational Site
  - Montgomery, Alabama, Forenede Stater, 36106
    - Novo Nordisk Investigational Site
  - Montgomery, Alabama, Forenede Stater, 36109
    - Novo Nordisk Investigational Site
- Arizona
  - Gilbert, Arizona, Forenede Stater, 85295
    - Novo Nordisk Investigational Site
  - Glendale, Arizona, Forenede Stater, 85308
    - Novo Nordisk Investigational Site
  - Litchfield Park, Arizona, Forenede Stater, 85340
    - Novo Nordisk Investigational Site
  - Phoenix, Arizona, Forenede Stater, 85050
    - Novo Nordisk Investigational Site
  - Tucson, Arizona, Forenede Stater, 85714
    - Novo Nordisk Investigational Site
  - Tucson, Arizona, Forenede Stater, 85704
    - Novo Nordisk Investigational Site
  - Tucson, Arizona, Forenede Stater, 85723
    - Novo Nordisk Investigational Site
- Arkansas
  - Little Rock, Arkansas, Forenede Stater, 72205
    - Novo Nordisk Investigational Site
  - Little Rock, Arkansas, Forenede Stater, 72205-5446
    - Novo Nordisk Investigational Site
  - Searcy, Arkansas, Forenede Stater, 72143
    - Novo Nordisk Investigational Site
- California
  - Chula Vista, California, Forenede Stater, 91910
    - Novo Nordisk Investigational Site
  - Concord, California, Forenede Stater, 94520
    - Novo Nordisk Investigational Site
  - Downey, California, Forenede Stater, 90242
    - Novo Nordisk Investigational Site
  - Duarte, California, Forenede Stater, 91010
    - Novo Nordisk Investigational Site
  - Encino, California, Forenede Stater, 91436
    - Novo Nordisk Investigational Site
  - Fresno, California, Forenede Stater, 93720
    - Novo Nordisk Investigational Site
  - Greenbrae, California, Forenede Stater, 94904
    - Novo Nordisk Investigational Site
  - Huntington Beach, California, Forenede Stater, 92648
    - Novo Nordisk Investigational Site
  - Inglewood, California, Forenede Stater, 90301
    - Novo Nordisk Investigational Site
  - La Jolla, California, Forenede Stater, 92037
    - Novo Nordisk Investigational Site
  - La Mesa, California, Forenede Stater, 91942
    - Novo Nordisk Investigational Site
  - Lancaster, California, Forenede Stater, 93534
    - Novo Nordisk Investigational Site
  - Long Beach, California, Forenede Stater, 90822
    - Novo Nordisk Investigational Site
  - Los Alamitos, California, Forenede Stater, 90720
    - Novo Nordisk Investigational Site
  - Mission Hills, California, Forenede Stater, 91345
    - Novo Nordisk Investigational Site
  - Montclair, California, Forenede Stater, 91763
    - Novo Nordisk Investigational Site
  - Monterey, California, Forenede Stater, 93940
    - Novo Nordisk Investigational Site
  - North Hollywood, California, Forenede Stater, 91606
    - Novo Nordisk Investigational Site
  - Palm Springs, California, Forenede Stater, 92262
    - Novo Nordisk Investigational Site
  - Poway, California, Forenede Stater, 92064
    - Novo Nordisk Investigational Site
  - San Diego, California, Forenede Stater, 92111
    - Novo Nordisk Investigational Site
  - San Diego, California, Forenede Stater, 92120
    - Novo Nordisk Investigational Site
  - San Ramon, California, Forenede Stater, 94583
    - Novo Nordisk Investigational Site
  - Santa Ana, California, Forenede Stater, 92704
    - Novo Nordisk Investigational Site
  - Sherman Oaks, California, Forenede Stater, 91403
    - Novo Nordisk Investigational Site
  - Thousand Oaks, California, Forenede Stater, 91360
    - Novo Nordisk Investigational Site
  - Tustin, California, Forenede Stater, 92780
    - Novo Nordisk Investigational Site
  - Ventura, California, Forenede Stater, 93003
    - Novo Nordisk Investigational Site
  - Vista, California, Forenede Stater, 92083
    - Novo Nordisk Investigational Site
  - Westminster, California, Forenede Stater, 92683
    - Novo Nordisk Investigational Site
- Colorado
  - Colorado Springs, Colorado, Forenede Stater, 80909
    - Novo Nordisk Investigational Site
  - Denver, Colorado, Forenede Stater, 80220
    - Novo Nordisk Investigational Site
  - Denver, Colorado, Forenede Stater, 80246
    - Novo Nordisk Investigational Site
  - Golden, Colorado, Forenede Stater, 80401
    - Novo Nordisk Investigational Site
- Connecticut
  - Danbury, Connecticut, Forenede Stater, 06810
    - Novo Nordisk Investigational Site
  - Norwalk, Connecticut, Forenede Stater, 06851
    - Novo Nordisk Investigational Site
  - Waterbury, Connecticut, Forenede Stater, 06708
    - Novo Nordisk Investigational Site
- Florida
  - Boca Raton, Florida, Forenede Stater, 33433
    - Novo Nordisk Investigational Site
  - Boynton Beach, Florida, Forenede Stater, 33472
    - Novo Nordisk Investigational Site
  - Bradenton, Florida, Forenede Stater, 34201
    - Novo Nordisk Investigational Site
  - Brandon, Florida, Forenede Stater, 33511
    - Novo Nordisk Investigational Site
  - Clearwater, Florida, Forenede Stater, 33756
    - Novo Nordisk Investigational Site
  - Cooper City, Florida, Forenede Stater, 33024
    - Novo Nordisk Investigational Site
  - Fleming Island, Florida, Forenede Stater, 32003
    - Novo Nordisk Investigational Site
  - Fort Lauderdale, Florida, Forenede Stater, 33316
    - Novo Nordisk Investigational Site
  - Gainesville, Florida, Forenede Stater, 32610
    - Novo Nordisk Investigational Site
  - Green Cove Springs, Florida, Forenede Stater, 32043
    - Novo Nordisk Investigational Site
  - Hialeah, Florida, Forenede Stater, 33012
    - Novo Nordisk Investigational Site
  - Jacksonville, Florida, Forenede Stater, 32216
    - Novo Nordisk Investigational Site
  - Jacksonville, Florida, Forenede Stater, 32207
    - Novo Nordisk Investigational Site
  - Miami, Florida, Forenede Stater, 33135
    - Novo Nordisk Investigational Site
  - Miami, Florida, Forenede Stater, 33136
    - Novo Nordisk Investigational Site
  - Miami, Florida, Forenede Stater, 33183
    - Novo Nordisk Investigational Site
  - Miami, Florida, Forenede Stater, 33155
    - Novo Nordisk Investigational Site
  - Miami, Florida, Forenede Stater, 33165
    - Novo Nordisk Investigational Site
  - Naples, Florida, Forenede Stater, 34119
    - Novo Nordisk Investigational Site
  - New Port Richey, Florida, Forenede Stater, 34652
    - Novo Nordisk Investigational Site
  - Orlando, Florida, Forenede Stater, 32806
    - Novo Nordisk Investigational Site
  - Panama City, Florida, Forenede Stater, 32401
    - Novo Nordisk Investigational Site
  - Ponte Vedra, Florida, Forenede Stater, 32081
    - Novo Nordisk Investigational Site
  - Port Charlotte, Florida, Forenede Stater, 33952
    - Novo Nordisk Investigational Site
  - Port Orange, Florida, Forenede Stater, 32127
    - Novo Nordisk Investigational Site
  - South Miami, Florida, Forenede Stater, 33143
    - Novo Nordisk Investigational Site
  - Tampa, Florida, Forenede Stater, 33624
    - Novo Nordisk Investigational Site
  - Tampa, Florida, Forenede Stater, 33619
    - Novo Nordisk Investigational Site
- Georgia
  - Atlanta, Georgia, Forenede Stater, 30339
    - Novo Nordisk Investigational Site
  - Decatur, Georgia, Forenede Stater, 30033
    - Novo Nordisk Investigational Site
  - Dunwoody, Georgia, Forenede Stater, 30338
    - Novo Nordisk Investigational Site
  - Lawrenceville, Georgia, Forenede Stater, 30046
    - Novo Nordisk Investigational Site
  - Roswell, Georgia, Forenede Stater, 30076
    - Novo Nordisk Investigational Site
  - Savannah, Georgia, Forenede Stater, 31406
    - Novo Nordisk Investigational Site
- Hawaii
  - Honolulu, Hawaii, Forenede Stater, 96814
    - Novo Nordisk Investigational Site
- Idaho
  - Idaho Falls, Idaho, Forenede Stater, 83404-7596
    - Novo Nordisk Investigational Site
- Illinois
  - Addison, Illinois, Forenede Stater, 60101
    - Novo Nordisk Investigational Site
  - Champaign, Illinois, Forenede Stater, 61821
    - Novo Nordisk Investigational Site
  - Chicago, Illinois, Forenede Stater, 60607
    - Novo Nordisk Investigational Site
  - Chicago, Illinois, Forenede Stater, 60616
    - Novo Nordisk Investigational Site
  - Crystal Lake, Illinois, Forenede Stater, 60012
    - Novo Nordisk Investigational Site
  - Gurnee, Illinois, Forenede Stater, 60031
    - Novo Nordisk Investigational Site
  - Hines, Illinois, Forenede Stater, 60141
    - Novo Nordisk Investigational Site
  - Springfield, Illinois, Forenede Stater, 62711
    - Novo Nordisk Investigational Site
  - Springfield, Illinois, Forenede Stater, 62702
    - Novo Nordisk Investigational Site
- Indiana
  - Brownsburg, Indiana, Forenede Stater, 46112
    - Novo Nordisk Investigational Site
  - Evansville, Indiana, Forenede Stater, 47714
    - Novo Nordisk Investigational Site
  - Franklin, Indiana, Forenede Stater, 46131
    - Novo Nordisk Investigational Site
  - Greenfield, Indiana, Forenede Stater, 46140
    - Novo Nordisk Investigational Site
  - Indianapolis, Indiana, Forenede Stater, 46254
    - Novo Nordisk Investigational Site
  - Michigan City, Indiana, Forenede Stater, 46360
    - Novo Nordisk Investigational Site
  - Muncie, Indiana, Forenede Stater, 47304
    - Novo Nordisk Investigational Site
- Iowa
  - Council Bluffs, Iowa, Forenede Stater, 51501
    - Novo Nordisk Investigational Site
- Kansas
  - Wichita, Kansas, Forenede Stater, 67205
    - Novo Nordisk Investigational Site
- Kentucky
  - Lexington, Kentucky, Forenede Stater, 40503
    - Novo Nordisk Investigational Site
  - Lexington, Kentucky, Forenede Stater, 40502
    - Novo Nordisk Investigational Site
  - Louisville, Kentucky, Forenede Stater, 40213
    - Novo Nordisk Investigational Site
  - Louisville, Kentucky, Forenede Stater, 40206
    - Novo Nordisk Investigational Site
  - Madisonville, Kentucky, Forenede Stater, 42431
    - Novo Nordisk Investigational Site
- Louisiana
  - Monroe, Louisiana, Forenede Stater, 71203
    - Novo Nordisk Investigational Site
  - New Orleans, Louisiana, Forenede Stater, 70119
    - Novo Nordisk Investigational Site
  - Shreveport, Louisiana, Forenede Stater, 71103
    - Novo Nordisk Investigational Site
  - Slidell, Louisiana, Forenede Stater, 70461-4231
    - Novo Nordisk Investigational Site
- Maine
  - Bangor, Maine, Forenede Stater, 04401
    - Novo Nordisk Investigational Site
- Maryland
  - Hyattsville, Maryland, Forenede Stater, 20782
    - Novo Nordisk Investigational Site
  - Rockville, Maryland, Forenede Stater, 20852
    - Novo Nordisk Investigational Site
- Massachusetts
  - Watertown, Massachusetts, Forenede Stater, 02472
    - Novo Nordisk Investigational Site
  - Worcester, Massachusetts, Forenede Stater, 01655
    - Novo Nordisk Investigational Site
- Michigan
  - Ann Arbor, Michigan, Forenede Stater, 48106
    - Novo Nordisk Investigational Site
  - Ann Arbor, Michigan, Forenede Stater, 48105
    - Novo Nordisk Investigational Site
  - Buckley, Michigan, Forenede Stater, 49620
    - Novo Nordisk Investigational Site
  - Detroit, Michigan, Forenede Stater, 48201
    - Novo Nordisk Investigational Site
  - Detroit, Michigan, Forenede Stater, 48202
    - Novo Nordisk Investigational Site
  - Kalamazoo, Michigan, Forenede Stater, 49009
    - Novo Nordisk Investigational Site
  - Livonia, Michigan, Forenede Stater, 48152
    - Novo Nordisk Investigational Site
  - Troy, Michigan, Forenede Stater, 48098
    - Novo Nordisk Investigational Site
- Mississippi
  - Olive Branch, Mississippi, Forenede Stater, 38654
    - Novo Nordisk Investigational Site
- Missouri
  - Hazelwood, Missouri, Forenede Stater, 63042
    - Novo Nordisk Investigational Site
  - Jefferson City, Missouri, Forenede Stater, 65109
    - Novo Nordisk Investigational Site
  - Kansas City, Missouri, Forenede Stater, 64111
    - Novo Nordisk Investigational Site
- Montana
  - Billings, Montana, Forenede Stater, 59101
    - Novo Nordisk Investigational Site
  - Kalispell, Montana, Forenede Stater, 59901
    - Novo Nordisk Investigational Site
- Nebraska
  - Elkhorn, Nebraska, Forenede Stater, 68022
    - Novo Nordisk Investigational Site
  - Fremont, Nebraska, Forenede Stater, 68025
    - Novo Nordisk Investigational Site
  - Omaha, Nebraska, Forenede Stater, 68114
    - Novo Nordisk Investigational Site
  - Omaha, Nebraska, Forenede Stater, 68105
    - Novo Nordisk Investigational Site
  - Omaha, Nebraska, Forenede Stater, 68124
    - Novo Nordisk Investigational Site
  - Omaha, Nebraska, Forenede Stater, 68144
    - Novo Nordisk Investigational Site
  - Omaha, Nebraska, Forenede Stater, 68198-4120
    - Novo Nordisk Investigational Site
- Nevada
  - Las Vegas, Nevada, Forenede Stater, 89148
    - Novo Nordisk Investigational Site
  - Las Vegas, Nevada, Forenede Stater, 89128
    - Novo Nordisk Investigational Site
  - Las Vegas, Nevada, Forenede Stater, 89120
    - Novo Nordisk Investigational Site
- New Hampshire
  - Nashua, New Hampshire, Forenede Stater, 03063
    - Novo Nordisk Investigational Site
- New Jersey
  - East Brunswick, New Jersey, Forenede Stater, 08816
    - Novo Nordisk Investigational Site
  - Hoboken, New Jersey, Forenede Stater, 07030
    - Novo Nordisk Investigational Site
- New York
  - Albany, New York, Forenede Stater, 12206
    - Novo Nordisk Investigational Site
  - Lake Success, New York, Forenede Stater, 11042
    - Novo Nordisk Investigational Site
  - Mineola, New York, Forenede Stater, 11501
    - Novo Nordisk Investigational Site
  - New Windsor, New York, Forenede Stater, 12553
    - Novo Nordisk Investigational Site
  - New York, New York, Forenede Stater, 10029
    - Novo Nordisk Investigational Site
  - North Massapequa, New York, Forenede Stater, 11758-1802
    - Novo Nordisk Investigational Site
  - Northport, New York, Forenede Stater, 11768
    - Novo Nordisk Investigational Site
  - Rochester, New York, Forenede Stater, 14607
    - Novo Nordisk Investigational Site
  - West Seneca, New York, Forenede Stater, 14224
    - Novo Nordisk Investigational Site
  - Westfield, New York, Forenede Stater, 14787
    - Novo Nordisk Investigational Site
- North Carolina
  - Asheville, North Carolina, Forenede Stater, 28803
    - Novo Nordisk Investigational Site
  - Asheville, North Carolina, Forenede Stater, 28801
    - Novo Nordisk Investigational Site
  - Burlington, North Carolina, Forenede Stater, 27215
    - Novo Nordisk Investigational Site
  - Cary, North Carolina, Forenede Stater, 27518
    - Novo Nordisk Investigational Site
  - Chapel Hill, North Carolina, Forenede Stater, 27517
    - Novo Nordisk Investigational Site
  - Charlotte, North Carolina, Forenede Stater, 28209
    - Novo Nordisk Investigational Site
  - Greenville, North Carolina, Forenede Stater, 27834
    - Novo Nordisk Investigational Site
  - Lexington, North Carolina, Forenede Stater, 27292
    - Novo Nordisk Investigational Site
  - Morehead City, North Carolina, Forenede Stater, 28557
    - Novo Nordisk Investigational Site
  - New Bern, North Carolina, Forenede Stater, 28562
    - Novo Nordisk Investigational Site
  - Statesville, North Carolina, Forenede Stater, 28625
    - Novo Nordisk Investigational Site
  - Whiteville, North Carolina, Forenede Stater, 28472
    - Novo Nordisk Investigational Site
  - Wilmington, North Carolina, Forenede Stater, 28401
    - Novo Nordisk Investigational Site
  - Winston-Salem, North Carolina, Forenede Stater, 27103
    - Novo Nordisk Investigational Site
- North Dakota
  - Fargo, North Dakota, Forenede Stater, 58104
    - Novo Nordisk Investigational Site
- Ohio
  - Cincinnati, Ohio, Forenede Stater, 45236
    - Novo Nordisk Investigational Site
  - Cleveland, Ohio, Forenede Stater, 44195
    - Novo Nordisk Investigational Site
  - Cleveland, Ohio, Forenede Stater, 44106-1702
    - Novo Nordisk Investigational Site
  - Cleveland, Ohio, Forenede Stater, 44121
    - Novo Nordisk Investigational Site
  - Columbus, Ohio, Forenede Stater, 43235
    - Novo Nordisk Investigational Site
  - Delaware, Ohio, Forenede Stater, 43015
    - Novo Nordisk Investigational Site
  - Franklin, Ohio, Forenede Stater, 45005
    - Novo Nordisk Investigational Site
  - Maumee, Ohio, Forenede Stater, 43537
    - Novo Nordisk Investigational Site
  - Mentor, Ohio, Forenede Stater, 44060
    - Novo Nordisk Investigational Site
  - Perrysburg, Ohio, Forenede Stater, 43551
    - Novo Nordisk Investigational Site
- Oklahoma
  - Norman, Oklahoma, Forenede Stater, 73069
    - Novo Nordisk Investigational Site
  - Oklahoma City, Oklahoma, Forenede Stater, 73104
    - Novo Nordisk Investigational Site
- Oregon
  - Portland, Oregon, Forenede Stater, 97239-3098
    - Novo Nordisk Investigational Site
- Pennsylvania
  - Altoona, Pennsylvania, Forenede Stater, 16602
    - Novo Nordisk Investigational Site
  - Beaver, Pennsylvania, Forenede Stater, 15009
    - Novo Nordisk Investigational Site
  - Danville, Pennsylvania, Forenede Stater, 17822
    - Novo Nordisk Investigational Site
  - Hermitage, Pennsylvania, Forenede Stater, 16148
    - Novo Nordisk Investigational Site
  - Philadelphia, Pennsylvania, Forenede Stater, 19107
    - Novo Nordisk Investigational Site
  - Philadelphia, Pennsylvania, Forenede Stater, 19114
    - Novo Nordisk Investigational Site
  - Pittsburgh, Pennsylvania, Forenede Stater, 15243
    - Novo Nordisk Investigational Site
  - Pittsburgh, Pennsylvania, Forenede Stater, 15212
    - Novo Nordisk Investigational Site
  - Smithfield, Pennsylvania, Forenede Stater, 15478
    - Novo Nordisk Investigational Site
  - Uniontown, Pennsylvania, Forenede Stater, 15401
    - Novo Nordisk Investigational Site
  - Upper Darby, Pennsylvania, Forenede Stater, 19082
    - Novo Nordisk Investigational Site
  - Wilkes-Barre, Pennsylvania, Forenede Stater, 18702
    - Novo Nordisk Investigational Site
- South Carolina
  - Anderson, South Carolina, Forenede Stater, 29621
    - Novo Nordisk Investigational Site
  - Greer, South Carolina, Forenede Stater, 29651
    - Novo Nordisk Investigational Site
  - Moncks Corner, South Carolina, Forenede Stater, 29461
    - Novo Nordisk Investigational Site
  - Murrells Inlet, South Carolina, Forenede Stater, 29576
    - Novo Nordisk Investigational Site
  - Myrtle Beach, South Carolina, Forenede Stater, 29572
    - Novo Nordisk Investigational Site
  - Orangeburg, South Carolina, Forenede Stater, 29118
    - Novo Nordisk Investigational Site
  - Spartanburg, South Carolina, Forenede Stater, 29303
    - Novo Nordisk Investigational Site
- Tennessee
  - Chattanooga, Tennessee, Forenede Stater, 37404
    - Novo Nordisk Investigational Site
  - Chattanooga, Tennessee, Forenede Stater, 37411
    - Novo Nordisk Investigational Site
  - Chattanooga, Tennessee, Forenede Stater, 37404-1192
    - Novo Nordisk Investigational Site
  - Kingsport, Tennessee, Forenede Stater, 37660
    - Novo Nordisk Investigational Site
  - Knoxville, Tennessee, Forenede Stater, 37938
    - Novo Nordisk Investigational Site
  - Memphis, Tennessee, Forenede Stater, 38119
    - Novo Nordisk Investigational Site
  - Memphis, Tennessee, Forenede Stater, 38163
    - Novo Nordisk Investigational Site
  - Nashville, Tennessee, Forenede Stater, 37212
    - Novo Nordisk Investigational Site
  - Nashville, Tennessee, Forenede Stater, 37203
    - Novo Nordisk Investigational Site
  - Nashville, Tennessee, Forenede Stater, 37208
    - Novo Nordisk Investigational Site
  - Tullahoma, Tennessee, Forenede Stater, 37388
    - Novo Nordisk Investigational Site
- Texas
  - Arlington, Texas, Forenede Stater, 76012
    - Novo Nordisk Investigational Site
  - Austin, Texas, Forenede Stater, 78731
    - Novo Nordisk Investigational Site
  - Austin, Texas, Forenede Stater, 78749
    - Novo Nordisk Investigational Site
  - Austin, Texas, Forenede Stater, 78705
    - Novo Nordisk Investigational Site
  - Carrollton, Texas, Forenede Stater, 75010
    - Novo Nordisk Investigational Site
  - Carrollton, Texas, Forenede Stater, 75007
    - Novo Nordisk Investigational Site
  - Corpus Christi, Texas, Forenede Stater, 78404
    - Novo Nordisk Investigational Site
  - Dallas, Texas, Forenede Stater, 75230
    - Novo Nordisk Investigational Site
  - Dallas, Texas, Forenede Stater, 75390-9302
    - Novo Nordisk Investigational Site
  - Dallas, Texas, Forenede Stater, 75231
    - Novo Nordisk Investigational Site
  - Dallas, Texas, Forenede Stater, 75246
    - Novo Nordisk Investigational Site
  - Fort Worth, Texas, Forenede Stater, 76117
    - Novo Nordisk Investigational Site
  - Fort Worth, Texas, Forenede Stater, 76132
    - Novo Nordisk Investigational Site
  - Houston, Texas, Forenede Stater, 77024
    - Novo Nordisk Investigational Site
  - Houston, Texas, Forenede Stater, 77061
    - Novo Nordisk Investigational Site
  - Houston, Texas, Forenede Stater, 77008
    - Novo Nordisk Investigational Site
  - Houston, Texas, Forenede Stater, 77070
    - Novo Nordisk Investigational Site
  - Houston, Texas, Forenede Stater, 77099
    - Novo Nordisk Investigational Site
  - Houston, Texas, Forenede Stater, 77060
    - Novo Nordisk Investigational Site
  - Houston, Texas, Forenede Stater, 77029
    - Novo Nordisk Investigational Site
  - Houston, Texas, Forenede Stater, 77093
    - Novo Nordisk Investigational Site
  - Humble, Texas, Forenede Stater, 77338
    - Novo Nordisk Investigational Site
  - Hurst, Texas, Forenede Stater, 76054
    - Novo Nordisk Investigational Site
  - Irving, Texas, Forenede Stater, 75039
    - Novo Nordisk Investigational Site
  - Lewisville, Texas, Forenede Stater, 75067
    - Novo Nordisk Investigational Site
  - Longview, Texas, Forenede Stater, 75605
    - Novo Nordisk Investigational Site
  - Lubbock, Texas, Forenede Stater, 79423
    - Novo Nordisk Investigational Site
  - Midland, Texas, Forenede Stater, 79707
    - Novo Nordisk Investigational Site
  - Odessa, Texas, Forenede Stater, 79761
    - Novo Nordisk Investigational Site
  - Pearland, Texas, Forenede Stater, 77584
    - Novo Nordisk Investigational Site
  - Richardson, Texas, Forenede Stater, 75080
    - Novo Nordisk Investigational Site
  - Round Rock, Texas, Forenede Stater, 78681
    - Novo Nordisk Investigational Site
  - San Antonio, Texas, Forenede Stater, 78229
    - Novo Nordisk Investigational Site
  - San Antonio, Texas, Forenede Stater, 78215
    - Novo Nordisk Investigational Site
  - San Antonio, Texas, Forenede Stater, 78228-6205
    - Novo Nordisk Investigational Site
  - San Antonio, Texas, Forenede Stater, 78258
    - Novo Nordisk Investigational Site
  - Splendora, Texas, Forenede Stater, 77372
    - Novo Nordisk Investigational Site
  - Sugar Land, Texas, Forenede Stater, 77478
    - Novo Nordisk Investigational Site
  - Sugar Land, Texas, Forenede Stater, 77479
    - Novo Nordisk Investigational Site
  - Waco, Texas, Forenede Stater, 76710
    - Novo Nordisk Investigational Site
- Utah
  - Salt Lake City, Utah, Forenede Stater, 84102
    - Novo Nordisk Investigational Site
  - Salt Lake City, Utah, Forenede Stater, 84132
    - Novo Nordisk Investigational Site
- Vermont
  - Bennington, Vermont, Forenede Stater, 05201
    - Novo Nordisk Investigational Site
  - South Burlington, Vermont, Forenede Stater, 05403
    - Novo Nordisk Investigational Site
- Virginia
  - Midlothian, Virginia, Forenede Stater, 23114
    - Novo Nordisk Investigational Site
  - Norfolk, Virginia, Forenede Stater, 23510
    - Novo Nordisk Investigational Site
  - Richmond, Virginia, Forenede Stater, 23249
    - Novo Nordisk Investigational Site
  - Winchester, Virginia, Forenede Stater, 22601-3834
    - Novo Nordisk Investigational Site
- Washington
  - Richland, Washington, Forenede Stater, 99352
    - Novo Nordisk Investigational Site
  - Spokane, Washington, Forenede Stater, 99201
    - Novo Nordisk Investigational Site
- Wisconsin
  - Kenosha, Wisconsin, Forenede Stater, 53144
    - Novo Nordisk Investigational Site
  - Milwaukee, Wisconsin, Forenede Stater, 53209
    - Novo Nordisk Investigational Site
  - Milwaukee, Wisconsin, Forenede Stater, 53295
    - Novo Nordisk Investigational Site
Grækenland
- - Athens, Grækenland, GR-17562
    - Novo Nordisk Investigational Site
  - Athens, Grækenland, GR-11527
    - Novo Nordisk Investigational Site
  - Athens, Grækenland, GR-115 27
    - Novo Nordisk Investigational Site
  - Athens, Grækenland, GR-10552
    - Novo Nordisk Investigational Site
  - Thessaloniki, Grækenland, GR-57001
    - Novo Nordisk Investigational Site
  - Thessaloniki, Grækenland, GR-54642
    - Novo Nordisk Investigational Site
Indien
- - Ludhiana, Indien, 141001
    - Novo Nordisk Investigational Site
  - New Delhi, Indien, 110001
    - Novo Nordisk Investigational Site
- Andhra Pradesh
  - Hyderabad, Andhra Pradesh, Indien, 500034
    - Novo Nordisk Investigational Site
  - Hyderbad, Andhra Pradesh, Indien, 500 012
    - Novo Nordisk Investigational Site
- Gujarat
  - Ahmedabad, Gujarat, Indien, 380006
    - Novo Nordisk Investigational Site
  - Ahmedabad, Gujarat, Indien, 380052
    - Novo Nordisk Investigational Site
  - Ahmedabad, Gujarat, Indien, 380007
    - Novo Nordisk Investigational Site
  - Ahmedabad, Gujarat, Indien, 380016
    - Novo Nordisk Investigational Site
- Haryana
  - Gurgaon, Haryana, Indien, 122001
    - Novo Nordisk Investigational Site
- Karnataka
  - Bangalore, Karnataka, Indien, 560034
    - Novo Nordisk Investigational Site
  - Bangalore, Karnataka, Indien, 560 017
    - Novo Nordisk Investigational Site
- Kerala
  - Kozhikode, Kerala, Indien, 673017
    - Novo Nordisk Investigational Site
- Madhya Pradesh
  - Indore, Madhya Pradesh, Indien, 452010
    - Novo Nordisk Investigational Site
- Maharashtra
  - Goa, Maharashtra, Indien, 403 202
    - Novo Nordisk Investigational Site
  - Mumbai, Maharashtra, Indien, 400008
    - Novo Nordisk Investigational Site
  - Mumbai, Maharashtra, Indien, 400012
    - Novo Nordisk Investigational Site
  - Mumbai, Maharashtra, Indien, 400022
    - Novo Nordisk Investigational Site
  - Mumbai, Maharashtra, Indien, 400010
    - Novo Nordisk Investigational Site
  - Mumbai, Maharashtra, Indien, 400007
    - Novo Nordisk Investigational Site
  - Pune, Maharashtra, Indien, 411001
    - Novo Nordisk Investigational Site
  - Pune, Maharashtra, Indien, 411040
    - Novo Nordisk Investigational Site
- New Delhi
  - New Dehli, New Delhi, Indien, 110029
    - Novo Nordisk Investigational Site
- Orissa
  - Bhubaneswar, Orissa, Indien, 751005
    - Novo Nordisk Investigational Site
- Punjab
  - Mohali, Punjab, Indien, 160062
    - Novo Nordisk Investigational Site
- Tamil Nadu
  - Chennai, Tamil Nadu, Indien, 600086
    - Novo Nordisk Investigational Site
  - Chennai, Tamil Nadu, Indien, 600031
    - Novo Nordisk Investigational Site
  - Coimbatore, Tamil Nadu, Indien, 641018
    - Novo Nordisk Investigational Site
- Uttar Pradesh
  - Lucknow, Uttar Pradesh, Indien, 226014
    - Novo Nordisk Investigational Site
- West Bengal
  - Kolkata, West Bengal, Indien, 700020
    - Novo Nordisk Investigational Site
  - Kolkata, West Bengal, Indien, 700054
    - Novo Nordisk Investigational Site
Italien
- - Bari, Italien, 70124
    - Novo Nordisk Investigational Site
  - Bergamo, Italien, 24127
    - Novo Nordisk Investigational Site
  - Catanzaro, Italien, 88100
    - Novo Nordisk Investigational Site
  - Chieti, Italien, 66100
    - Novo Nordisk Investigational Site
  - Milano, Italien, 20122
    - Novo Nordisk Investigational Site
  - Milano, Italien, 20162
    - Novo Nordisk Investigational Site
  - Milano (MI), Italien, 20132
    - Novo Nordisk Investigational Site
  - Olbia, Italien, 07026
    - Novo Nordisk Investigational Site
  - Padova, Italien, 35143
    - Novo Nordisk Investigational Site
  - Palermo, Italien, 90127
    - Novo Nordisk Investigational Site
  - Ravenna, Italien, 48121
    - Novo Nordisk Investigational Site
  - Roma, Italien, 00161
    - Novo Nordisk Investigational Site
  - Roma, Italien, 00133
    - Novo Nordisk Investigational Site
  - Sesto San Giovanni (MI), Italien, 20099
    - Novo Nordisk Investigational Site
Japan
- - Chuo-ku, Tokyo, Japan, 103-0002
    - Novo Nordisk Investigational Site
  - Kanagawa, Japan, 235-0045
    - Novo Nordisk Investigational Site
  - Kumamoto, Japan, 862-0976
    - Novo Nordisk Investigational Site
  - Miyazaki, Japan, 880-0034
    - Novo Nordisk Investigational Site
  - Nagano, Japan, 390-8621
    - Novo Nordisk Investigational Site
  - Ota-ku, Japan, 144 0035
    - Novo Nordisk Investigational Site
  - Ota-ku, Tokyo, Japan, 1430015
    - Novo Nordisk Investigational Site
  - Shinjuku-ku, Tokyo, Japan, 162-8655
    - Novo Nordisk Investigational Site
Korea, Republikken
- - Goyang, Korea, Republikken, 10380
    - Novo Nordisk Investigational Site
  - Seoul, Korea, Republikken, 02841
    - Novo Nordisk Investigational Site
  - Seoul, Korea, Republikken, 03080
    - Novo Nordisk Investigational Site
  - Suwon-si, Gyeonggi-do, Korea, Republikken, 16247
    - Novo Nordisk Investigational Site
Kroatien
- - Bjelovar, Kroatien, 43000
    - Novo Nordisk Investigational Site
  - Osijek, Kroatien, 31 000
    - Novo Nordisk Investigational Site
  - Slavonski Brod, Kroatien, 35 000
    - Novo Nordisk Investigational Site
  - Zagreb, Kroatien, 10 000
    - Novo Nordisk Investigational Site
  - Zagreb, Kroatien, 10000
    - Novo Nordisk Investigational Site
Malaysia
- - Alor Setar, Malaysia, 05460
    - Novo Nordisk Investigational Site
  - Kota Samarahan, Malaysia, 94300
    - Novo Nordisk Investigational Site
  - Kuala Lumpur, Malaysia, 59100
    - Novo Nordisk Investigational Site
  - Kuantan, Malaysia, 25100
    - Novo Nordisk Investigational Site
  - Melaka, Malaysia, 75400
    - Novo Nordisk Investigational Site
  - Serdang, Malaysia, 43000
    - Novo Nordisk Investigational Site
  - Seremban, Malaysia, 70300
    - Novo Nordisk Investigational Site
Mexico
- - Aguascalientes, Mexico, 20230
    - Novo Nordisk Investigational Site
  - Chihuahua, Mexico, 31200
    - Novo Nordisk Investigational Site
  - San Luis Potosi, Mexico, 78200
    - Novo Nordisk Investigational Site
- Jalisco
  - Guadalajara, Jalisco, Mexico, 44600
    - Novo Nordisk Investigational Site
  - Guadalajara, Jalisco, Mexico, 44130
    - Novo Nordisk Investigational Site
  - Guadalajara, Jalisco, Mexico, 44650
    - Novo Nordisk Investigational Site
  - Guadalajara, Jalisco, Mexico, 44670
    - Novo Nordisk Investigational Site
  - Guadalajara, Jalisco, Mexico, 44150
    - Novo Nordisk Investigational Site
- Morelos
  - Cuernavaca, Morelos, Mexico, 62250
    - Novo Nordisk Investigational Site
- México, D.F.
  - Distrito Federal, México, D.F., Mexico, 14080
    - Novo Nordisk Investigational Site
Polen
- - Bytom, Polen, 41-902
    - Novo Nordisk Investigational Site
  - Gdansk, Polen, 80-546
    - Novo Nordisk Investigational Site
  - Krakow, Polen, 31-455
    - Novo Nordisk Investigational Site
  - Oswiecim, Polen, 32-600
    - Novo Nordisk Investigational Site
  - Poznan, Polen, 60-589
    - Novo Nordisk Investigational Site
  - Szczecin, Polen, 70-506
    - Novo Nordisk Investigational Site
  - Warszawa, Polen, 02-507
    - Novo Nordisk Investigational Site
  - Zamosc, Polen, 22-400
    - Novo Nordisk Investigational Site
Rumænien
- Alba
  - Alba Iulia, Alba, Rumænien, 510053
    - Novo Nordisk Investigational Site
- Maramures
  - Baia Mare, Maramures, Rumænien, 430222
    - Novo Nordisk Investigational Site
- Mures
  - Targu Mures, Mures, Rumænien, 540142
    - Novo Nordisk Investigational Site
- Prahova
  - Ploiesti, Prahova, Rumænien, 100163
    - Novo Nordisk Investigational Site
Spanien
- - Granada, Spanien, 18012
    - Novo Nordisk Investigational Site
  - Granada, Spanien, 18003
    - Novo Nordisk Investigational Site
  - Madrid, Spanien, 28046
    - Novo Nordisk Investigational Site
  - Málaga, Spanien, 29006
    - Novo Nordisk Investigational Site
  - Sevilla, Spanien, 41009
    - Novo Nordisk Investigational Site
  - Valencia, Spanien, 46014
    - Novo Nordisk Investigational Site
  - Valencia, Spanien, 46015
    - Novo Nordisk Investigational Site
Sydafrika
- Eastern Cape
  - Port Elizabeth, Eastern Cape, Sydafrika, 6045
    - Novo Nordisk Investigational Site
  - Port Elizabeth, Eastern Cape, Sydafrika, 6014
    - Novo Nordisk Investigational Site
- Gauteng
  - Johannesburg, Gauteng, Sydafrika, 2193
    - Novo Nordisk Investigational Site
  - Johannesburg, Gauteng, Sydafrika, 1818
    - Novo Nordisk Investigational Site
  - Johannesburg, Gauteng, Sydafrika, 2198
    - Novo Nordisk Investigational Site
  - Pretoria, Gauteng, Sydafrika, 0001
    - Novo Nordisk Investigational Site
- KwaZulu-Natal
  - Durban, KwaZulu-Natal, Sydafrika, 4001
    - Novo Nordisk Investigational Site
  - Durban, KwaZulu-Natal, Sydafrika, 4092
    - Novo Nordisk Investigational Site
  - Umkomaas, KwaZulu-Natal, Sydafrika, 4170
    - Novo Nordisk Investigational Site
- Mpumalanga
  - Middleburg, Mpumalanga, Sydafrika, 1055
    - Novo Nordisk Investigational Site
- North West
  - Brits, North West, Sydafrika, 0250
    - Novo Nordisk Investigational Site
- Western Cape
  - Cape Town, Western Cape, Sydafrika, 7130
    - Novo Nordisk Investigational Site
  - Cape Town, Western Cape, Sydafrika, 7500
    - Novo Nordisk Investigational Site
  - Cape Town, Western Cape, Sydafrika, 7700
    - Novo Nordisk Investigational Site
  - Cape Town, Western Cape, Sydafrika, 7460
    - Novo Nordisk Investigational Site
Thailand
- - Bangkok, Thailand, 10400
    - Novo Nordisk Investigational Site
  - Bangkok, Thailand, 10330
    - Novo Nordisk Investigational Site
  - Bangkoknoi, Bangkok, Thailand, 10700
    - Novo Nordisk Investigational Site
  - Chiang Mai, Thailand, 50200
    - Novo Nordisk Investigational Site
  - Nakhon Ratchasima, Thailand, 30000
    - Novo Nordisk Investigational Site

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

50 år og ældre (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Køn, der er berettiget til at studere

Alle

Beskrivelse

Inclusion Criteria: - Type 2 diabetes - Age above or equal to 50 years with predefined previous cardiovascular disease(s) or renal disease or age above or equal to 60 years with predefined cardiovascular risk factors - HbA1c (glycosylated haemoglobin) above or equal to 7.0% or HbA1c below 7.0% and current insulin treatment corresponding to above or equal to 20 U of basal insulin per day - One or more oral or injectable antidiabetic agent(s) Exclusion Criteria: - An acute coronary or cerebrovascular event in the previous 60 days - Planned coronary, carotid or peripheral artery revascularisation - Chronic heart failure NYHA (New York Heart Association) class IV - Current or past (within the last 5 years) malignant neoplasms (except basal cell and squamous cell skin carcinoma)

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Primært formål: Behandling
Tildeling: Randomiseret
Interventionel model: Parallel tildeling
Maskning: Dobbelt

Antal våben

Våben og indgreb

Deltagergruppe / Arm	Intervention / Behandling
Eksperimentel: Insulin degludec (IDeg) All subjects will continue their current antidiabetic therapy except for the basal insulin component (if any) that will be replaced by the investigational product.	Medicin: insulin degludec Injected once daily subcutaneously (s.c., under the skin)
Aktiv komparator: Insulin glargine (IGlar) All subjects will continue their current antidiabetic therapy except for the basal insulin component (if any) that will be replaced by the investigational product.	Medicin: insulin glargine Injected once daily subcutaneously (s.c., under the skin)

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Time From Randomisation to First Occurrence of a Major Adverse Cardiovascular Event (MACE): Cardiovascular Death, Non-fatal Myocardial Infarction, or Non-fatal Stroke Tidsramme: From randomisation to individual end of trial date (maximum patient year observation: 2.75 years)	Time from randomisation to first occurrence of an event adjudication committee (EAC)-confirmed 3-component major adverse cardiovascular event (MACE): cardiovascular death, non-fatal myocardial infarction, or nonfatal stroke. Events with EAC-confirmed onset date between randomisation and individual end of trial were included in the analyses. The number of subjects experiencing first EAC-confirmed MACEs, date between randomisation to the end of trial, both days included were presented. The trial was event driven and planned to last up to a maximum of 60.5 months. The actual trial duration (time from first subject first visit to last subject last visit) was 35.6 months. The maximum trial duration for a single subject was 33.1 months.	From randomisation to individual end of trial date (maximum patient year observation: 2.75 years)

Sekundære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Number of EAC-confirmed Severe Hypoglycaemic Episodes Tidsramme: From randomisation to individual end of trial (maximum patient year observation: 2.75 years)	Number of severe hypoglycaemic episodes from week 0 to the last assessment (up to 35.6 months). The episode of severe hypoglycaemia is an episode requiring assistance of another person to actively administer carbohydrate, glucagon, or take other corrective actions. The trial was event driven and planned to last up to a maximum of 60.5 months. The actual trial duration (time from first subject first visit to last subject last visit) was 35.6 months. The maximum trial duration for a single subject was 33.1 months.	From randomisation to individual end of trial (maximum patient year observation: 2.75 years)
Occurrence of at Least One EAC Confirmed Severe Hypoglycaemic Episode Within a Subject (Yes/no) Tidsramme: From randomisation to individual end of trial date (maximum patient year observation: 2.75 years)	Occurrence of at least one EAC-confirmed severe hypoglycaemic episode within a subject from week 0 to the last assessment (up to 35.6 months). The episode of severe hypoglycaemia is an episode requiring assistance of another person to actively administer carbohydrate, glucagon, or take other corrective actions.	From randomisation to individual end of trial date (maximum patient year observation: 2.75 years)
Change in Glycosylated Haemoglobin (HbA1c) Tidsramme: Randomisation to 24 months	Mean change in HbA1c from week 0 to month 24.	Randomisation to 24 months

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Novo Nordisk A/S

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Hjælpsomme links

Clinical Trials at Novo Nordisk

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

29. oktober 2013

Primær færdiggørelse (Faktiske)

16. oktober 2016

Studieafslutning (Faktiske)

16. oktober 2016

Datoer for studieregistrering

Først indsendt

8. oktober 2013

Først indsendt, der opfyldte QC-kriterier

8. oktober 2013

Først opslået (Skøn)

10. oktober 2013

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

24. juli 2019

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

10. juli 2019

Sidst verificeret

1. juli 2019

Mere information

Begreber relateret til denne undersøgelse

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

EX1250-4080
2013-002371-17 (EudraCT nummer)
U1111-1141-7614 (Anden identifikator: WHO)
JapicCTI-142464 (Registry Identifier: JAPIC)

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Kliniske forsøg med Diabetes mellitus, type 2

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Sanofi

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Et forsøg, der undersøger de farmakodynamiske og farmakokinetiske egenskaber af insulin degludec/insulin aspart 15 hos forsøgspersoner med type 1-diabetes

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Novo Nordisk A/S

Afsluttet

Et randomiseret forsøg, der sammenligner effektivitet og sikkerhed efter intensivering med enten insulin aspart én gang dagligt som tilføjelse eller ændring til basalbolusbehandling med insulin degludec og insulin aspart hos forsøgspersoner med type 2-diabetes, der tidligere er behandlet med insulin degludec/insulin aspart to gange dagligt (BOOST®)

Diabetes mellitus, type 2 | Diabetes

Forenede Stater, Malaysia, Tyskland, Algeriet, Kalkun
Novo Nordisk A/S

Afsluttet

Sammenligning af eksplorativ formulering af insulin Degludec og insulin Aspart co-formulering versus eksplorativ formulering af insulin Degludec og insulin Aspart separat sammenlignet med bifasisk insulin Aspart 30 hos mandlige patienter med diabetes

Diabetes mellitus, type 2 | Diabetes | Diabetes mellitus, type 1

Tyskland
Sunshine Lake Pharma Co., Ltd.

Ikke rekrutterer endnu

En undersøgelse af Insulin Degludec/Insulin Aspart Biosimilar (22011) sammenlignet med Insulin Degludec/Insulin Aspart(Ryzodeg) hos deltagere med type 2-diabetes i Kina

Diabetes
Novo Nordisk A/S

Afsluttet

En forskningsundersøgelse for at sammenligne to typer insulin, et nyt insulin, insulin Icodec og et tilgængeligt insulin, Insulin Degludec, hos mennesker med type 2-diabetes, som ikke har brugt insulin før (FREMOVER 3) (ONWARDS 3)

Diabetes mellitus, type 2

Forenede Stater, Mexico, Puerto Rico, Canada, Danmark, Frankrig, Østrig, Taiwan, Tjekkiet, Brasilien, Kina, Argentina
Novo Nordisk A/S

Afsluttet

Et forsøg, der undersøger de farmakodynamiske egenskaber af NN5401 hos forsøgspersoner med type 1-diabetes

Diabetes | Diabetes mellitus, type 1

Tyskland
Sunshine Lake Pharma Co., Ltd.

Afsluttet

En klinisk undersøgelse, der sammenligner farmakokinetik og farmakodynamiske egenskaber ved insulin Degludec-injektion (RD15003) og Insulin Degludec-injektion (Tresiba®) hos raske forsøgspersoner

Type 2 diabetes

Kina
Novo Nordisk A/S

Afsluttet

Effekt og sikkerhed af hurtigere virkende insulin aspart sammenlignet med NovoRapid® både i kombination med insulin degludec hos børn og unge med type 1-diabetes (onset®7)

Diabetes | Diabetes mellitus, type 1

Tyskland, Forenede Stater, Indien, Israel, Italien, Den Russiske Føderation, Japan, Finland, Serbien, Kalkun, Bulgarien, Estland, Tjekkiet, Litauen, Ukraine, Polen, Letland, Puerto Rico

A Trial Comparing Cardiovascular Safety of Insulin Degludec Versus Insulin Glargine in Subjects With Type 2 Diabetes at High Risk of Cardiovascular Events (DEVOTE)

Studieoversigt

Status

Betingelser

Intervention / Behandling

Undersøgelsestype

Tilmelding (Faktiske)

Fase

Kontakter og lokationer

Studiesteder

Deltagelseskriterier

Berettigelseskriterier

Aldre berettiget til at studere

Tager imod sunde frivillige

Køn, der er berettiget til at studere

Beskrivelse

Studieplan

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Antal våben

Våben og indgreb

Deltagergruppe / Arm

Intervention / Behandling

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Sekundære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Samarbejdspartnere og efterforskere

Sponsor

Publikationer og nyttige links

Generelle publikationer

Hjælpsomme links

Datoer for undersøgelser

Studer store datoer

Studiestart (Faktiske)

Primær færdiggørelse (Faktiske)

Studieafslutning (Faktiske)

Datoer for studieregistrering

Først indsendt

Først indsendt, der opfyldte QC-kriterier

Først opslået (Skøn)

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

Sidst verificeret

Mere information

Begreber relateret til denne undersøgelse

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

Kliniske forsøg med Diabetes mellitus, type 2

Kliniske forsøg med insulin degludec

Søg i lignende forsøg

Sponsorer og samarbejdspartnere

Medicinske tilstande

Narkotikainterventioner

CROs by country

CROs in Algeria

Betingelser

Sjældne sygdomme

Narkotikainterventioner

Kosttilskud

Sponsor / samarbejdspartnere

Placeringer