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Tilføjelse af Nivolumab til sædvanlig behandling for mennesker med avanceret mave- eller spiserørskræft, PARAMMUNE-forsøget

29. oktober 2026 opdateret af: National Cancer Institute (NCI)

Randomized Phase II/III Trial of 2nd Line Nivolumab + Paclitaxel + Ramucirumab Versus Paclitaxel + Ramucirumab in Patients With PD-L1 CPS >/= 1 Advanced Gastric and Esophageal Adenocarcinoma (PARAMUNE)

This phase II/III trial compares the addition of nivolumab to the usual treatment of paclitaxel and ramucirumab to paclitaxel and ramucirumab alone in treating patients with gastric or esophageal adenocarcinoma that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced). A monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Ramucirumab is a monoclonal antibody that may prevent the growth of new blood vessels that tumors need to grow. Paclitaxel is in a class of medications called antimicrotubule agents. It stops cancer cells from growing and dividing and may kill them. Adding nivolumab to ramucirumab and paclitaxel may work better to treat patients with advanced stomach or esophageal cancer.

Studieoversigt

Status

Rekruttering

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

PRIMARY OBJECTIVES:

I. To assess whether progression-free survival (PFS) is sufficiently improved in participants randomized to nivolumab + paclitaxel + ramucirumab compared to those randomized to paclitaxel + ramucirumab to warrant a phase III study with overall survival (OS) as the primary endpoint. (Phase II) II. To compare OS in participants randomized to nivolumab + paclitaxel + ramucirumab versus those randomized to paclitaxel + ramucirumab. (Phase III)

SECONDARY OBJECTIVES:

I. To compare PFS between those randomized to nivolumab + paclitaxel + ramucirumab versus those randomized to paclitaxel + ramucirumab. (Phase III) II. To compare OS between participants randomized to nivolumab + paclitaxel + ramucirumab compared to those randomized to paclitaxel + ramucirumab in the event that the trial is completed before the phase III portion.

III. To compare the overall response rate (ORR, including confirmed and unconfirmed, complete, and partial response, according to Response Evaluation Criteria in Solid Tumors [RECIST 1.1] criteria) between those randomized to nivolumab + paclitaxel + ramucirumab compared to those randomized to paclitaxel + ramucirumab among participants with measurable disease.

IV. To compare the overall disease control rate (DCR = ORR + stable disease) between those randomized to nivolumab + paclitaxel + ramucirumab compared to those randomized to paclitaxel + ramucirumab among participants with measurable disease.

V. To evaluate the safety and tolerability of each treatment regimen. VI. To compare health-related quality of life (QOL) by treatment arm at 8 weeks after randomization, measured using the Functional Assessment of Cancer Therapy - Gastric (FACT-Ga) Trial Outcome Index (TOI).

VII. To compare health-related QOL between treatment arms at 8 weeks after randomization using the FACT-Ga total score.

VIII. To compare longitudinal changes in health-related QOL between treatment arms using FACT-Ga TOI up to 24 weeks after randomization.

IX. To compare patient-reported symptoms using selected Patient-Reported Outcomes-Common Terminology Criteria for Adverse Events (PRO-CTCAE) items including gastrointestinal as well as constitutional symptoms of fatigue, anorexia, and weight loss between treatment arms.

OUTLINE: Patients are randomized to 1 of 2 arms.

ARM 1: Patients receive nivolumab intravenously (IV) over 30 minutes on day 1 of each cycle, ramucirumab IV over 30-60 minutes on days 1 and 15 of each cycle, and paclitaxel IV over 60 minutes on days 1, 8 and 15 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients undergo computed tomography (CT) scan and magnetic resonance imaging (MRI) throughout the study. Patients may also optionally undergo blood sample collection on study.

ARM 2: Patients receive ramucirumab IV over 30-60 minutes on days 1 and 15 of each cycle and paclitaxel IV over 60 minutes on days 1, 8 and 15 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan and MRI throughout the study. Patients may also optionally undergo blood sample collection on study.

After completion of study treatment, patients are followed up at 30, 60, 90 days and then every 6 months for up to 3 years.

Undersøgelsestype

Interventionel

Tilmelding (Anslået)

224

Fase

Fase 2
Fase 3

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Forenede Stater
- Arkansas
  - Little Rock, Arkansas, Forenede Stater, 72205
    - Rekruttering
    - University of Arkansas for Medical Sciences
    - Ledende efterforsker:
      
      Rangaswamy Govindarajan
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 501-686-8274
  - Little Rock, Arkansas, Forenede Stater, 72205
    - Rekruttering
    - Baptist Health Medical Center - Little Rock
    - Ledende efterforsker:
      
      Rangaswamy Govindarajan
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 501-202-4715
- California
  - Anaheim, California, Forenede Stater, 92806
    - Rekruttering
    - Kaiser Permanente-Anaheim
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-398-3996
      
      E-mail: clinical.trials@kp.org
    - Ledende efterforsker:
      
      Gary L. Buchschacher
  - Baldwin Park, California, Forenede Stater, 91706
    - Rekruttering
    - Kaiser Permanente-Baldwin Park
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-398-3996
      
      E-mail: clinical.trials@kp.org
    - Ledende efterforsker:
      
      Gary L. Buchschacher
  - Bellflower, California, Forenede Stater, 90706
    - Rekruttering
    - Kaiser Permanente-Bellflower
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-398-3996
      
      E-mail: clinical.trials@kp.org
    - Ledende efterforsker:
      
      Gary L. Buchschacher
  - Beverly Hills, California, Forenede Stater, 90211
    - Rekruttering
    - Tower Cancer Research Foundation
    - Kontakt:
      
      Site Public Contact
      
      E-mail: towercancerresearch@toweroncology.com
    - Ledende efterforsker:
      
      Jun Gong
  - Dublin, California, Forenede Stater, 94568
    - Rekruttering
    - Kaiser Permanente Dublin
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - Fontana, California, Forenede Stater, 92335
    - Rekruttering
    - Kaiser Permanente-Fontana
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-398-3996
      
      E-mail: clinical.trials@kp.org
    - Ledende efterforsker:
      
      Gary L. Buchschacher
  - Fremont, California, Forenede Stater, 94538
    - Rekruttering
    - Kaiser Permanente-Fremont
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
      
      E-mail: Kpoct@kp.org
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - Fresno, California, Forenede Stater, 93720
    - Rekruttering
    - Kaiser Permanente-Fresno
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
      
      E-mail: Kpoct@kp.org
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - Fresno, California, Forenede Stater, 93720
    - Rekruttering
    - Kaiser Permanente Fresno Orchard Plaza
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 833-574-2273
  - Harbor City, California, Forenede Stater, 90710
    - Rekruttering
    - Kaiser Permanente South Bay
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-398-3996
      
      E-mail: clinical.trials@kp.org
    - Ledende efterforsker:
      
      Gary L. Buchschacher
  - Irvine, California, Forenede Stater, 92618
    - Rekruttering
    - Kaiser Permanente-Irvine
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-398-3996
      
      E-mail: clinical.trials@kp.org
    - Ledende efterforsker:
      
      Gary L. Buchschacher
  - La Jolla, California, Forenede Stater, 92093
    - Rekruttering
    - UC San Diego Moores Cancer Center
    - Ledende efterforsker:
      
      Aaron Miller
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 858-822-5354
      
      E-mail: cancercto@ucsd.edu
  - Los Angeles, California, Forenede Stater, 90048
    - Rekruttering
    - Cedars-Sinai Medical Center
    - Ledende efterforsker:
      
      Jun Gong
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 310-423-2133
      
      E-mail: Cancer.trial.info@cshs.org
  - Los Angeles, California, Forenede Stater, 90027
    - Rekruttering
    - Kaiser Permanente Los Angeles Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-398-3996
      
      E-mail: clinical.trials@kp.org
    - Ledende efterforsker:
      
      Gary L. Buchschacher
  - Los Angeles, California, Forenede Stater, 90034
    - Rekruttering
    - Kaiser Permanente West Los Angeles
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-398-3996
      
      E-mail: clinical.trials@kp.org
    - Ledende efterforsker:
      
      Gary L. Buchschacher
  - Los Angeles, California, Forenede Stater, 90033
    - Rekruttering
    - USC / Norris Comprehensive Cancer Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 323-865-0451
    - Ledende efterforsker:
      
      Syma Iqbal
  - Los Angeles, California, Forenede Stater, 90020
    - Rekruttering
    - Keck Medicine of USC Koreatown
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 213-388-0908
    - Ledende efterforsker:
      
      Syma Iqbal
  - Los Angeles, California, Forenede Stater, 90033
    - Rekruttering
    - Los Angeles General Medical Center
    - Ledende efterforsker:
      
      Syma Iqbal
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 323-865-0451
      
      E-mail: uscnorrisinfo@med.usc.edu
  - Modesto, California, Forenede Stater, 95356
    - Rekruttering
    - Kaiser Permanente-Modesto
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
      
      E-mail: Kpoct@kp.org
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - Modesto, California, Forenede Stater, 95356
    - Rekruttering
    - Kaiser Permanente- Modesto MOB II
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - Newport Beach, California, Forenede Stater, 92663
    - Rekruttering
    - USC Norris Oncology/Hematology-Newport Beach
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 323-865-0451
    - Ledende efterforsker:
      
      Syma Iqbal
  - Oakland, California, Forenede Stater, 94611
    - Rekruttering
    - Kaiser Permanente-Oakland
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
      
      E-mail: Kpoct@kp.org
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - Ontario, California, Forenede Stater, 91761
    - Rekruttering
    - Kaiser Permanente-Ontario
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-398-3996
      
      E-mail: clinical.trials@kp.org
    - Ledende efterforsker:
      
      Gary L. Buchschacher
  - Panorama City, California, Forenede Stater, 91402
    - Rekruttering
    - Kaiser Permanente - Panorama City
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-398-3996
      
      E-mail: clinical.trials@kp.org
    - Ledende efterforsker:
      
      Gary L. Buchschacher
  - Riverside, California, Forenede Stater, 92505
    - Rekruttering
    - Kaiser Permanente-Riverside
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-398-3996
      
      E-mail: clinical.trials@kp.org
    - Ledende efterforsker:
      
      Gary L. Buchschacher
  - Roseville, California, Forenede Stater, 95661
    - Rekruttering
    - Kaiser Permanente-Roseville
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
      
      E-mail: Kpoct@kp.org
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - Sacramento, California, Forenede Stater, 95814
    - Rekruttering
    - Kaiser Permanente Downtown Commons
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
      
      E-mail: kpoct@kp.org
  - Sacramento, California, Forenede Stater, 95823
    - Rekruttering
    - Kaiser Permanente-South Sacramento
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
      
      E-mail: Kpoct@kp.org
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - Sacramento, California, Forenede Stater, 95817
    - Aktiv, ikke rekrutterende
    - University of California Davis Comprehensive Cancer Center
  - San Diego, California, Forenede Stater, 92120
    - Rekruttering
    - Kaiser Permanente-San Diego Zion
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-398-3996
      
      E-mail: clinical.trials@kp.org
    - Ledende efterforsker:
      
      Gary L. Buchschacher
  - San Francisco, California, Forenede Stater, 94115
    - Rekruttering
    - Kaiser Permanente-San Francisco
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
      
      E-mail: Kpoct@kp.org
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - San Jose, California, Forenede Stater, 95119
    - Rekruttering
    - Kaiser Permanente-Santa Teresa-San Jose
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
      
      E-mail: Kpoct@kp.org
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - San Leandro, California, Forenede Stater, 94577
    - Rekruttering
    - Kaiser Permanente San Leandro
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
      
      E-mail: Kpoct@kp.org
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - San Marcos, California, Forenede Stater, 92078
    - Rekruttering
    - Kaiser Permanente-San Marcos
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-398-3996
      
      E-mail: clinical.trials@kp.org
    - Ledende efterforsker:
      
      Gary L. Buchschacher
  - San Rafael, California, Forenede Stater, 94903
    - Rekruttering
    - Kaiser San Rafael-Gallinas
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
      
      E-mail: Kpoct@kp.org
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - Santa Clara, California, Forenede Stater, 95051
    - Rekruttering
    - Kaiser Permanente Medical Center - Santa Clara
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
      
      E-mail: Kpoct@kp.org
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - Santa Rosa, California, Forenede Stater, 95403
    - Rekruttering
    - Kaiser Permanente-Santa Rosa
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
      
      E-mail: Kpoct@kp.org
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - South San Francisco, California, Forenede Stater, 94080
    - Rekruttering
    - Kaiser Permanente-South San Francisco
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
      
      E-mail: Kpoct@kp.org
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - Vallejo, California, Forenede Stater, 94589
    - Rekruttering
    - Kaiser Permanente-Vallejo
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
      
      E-mail: Kpoct@kp.org
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - Walnut Creek, California, Forenede Stater, 94596
    - Rekruttering
    - Kaiser Permanente-Walnut Creek
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-642-4691
      
      E-mail: Kpoct@kp.org
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - Woodland Hills, California, Forenede Stater, 91367
    - Rekruttering
    - Kaiser Permanente-Woodland Hills
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-398-3996
      
      E-mail: clinical.trials@kp.org
    - Ledende efterforsker:
      
      Gary L. Buchschacher
- Colorado
  - Colorado Springs, Colorado, Forenede Stater, 80909
    - Rekruttering
    - UCHealth Memorial Hospital Central
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 719-365-2406
    - Ledende efterforsker:
      
      Shin Yin Lee
  - Colorado Springs, Colorado, Forenede Stater, 80920
    - Rekruttering
    - Memorial Hospital North
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 719-364-6700
    - Ledende efterforsker:
      
      Shin Yin Lee
  - Fort Collins, Colorado, Forenede Stater, 80524
    - Rekruttering
    - Poudre Valley Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 970-297-6150
    - Ledende efterforsker:
      
      Shin Yin Lee
  - Fort Collins, Colorado, Forenede Stater, 80528
    - Rekruttering
    - Cancer Care and Hematology-Fort Collins
    - Kontakt:
      
      Site Public Contact
      
      E-mail: protocols@swog.org
    - Ledende efterforsker:
      
      Shin Yin Lee
  - Greeley, Colorado, Forenede Stater, 80631
    - Rekruttering
    - UCHealth Greeley Hospital
    - Kontakt:
      
      Site Public Contact
      
      E-mail: protocols@swog.org
    - Ledende efterforsker:
      
      Shin Yin Lee
  - Loveland, Colorado, Forenede Stater, 80538
    - Rekruttering
    - Medical Center of the Rockies
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 970-203-7083
    - Ledende efterforsker:
      
      Shin Yin Lee
- Connecticut
  - Derby, Connecticut, Forenede Stater, 06418
    - Rekruttering
    - Smilow Cancer Hospital-Derby Care Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 203-785-5702
      
      E-mail: canceranswers@yale.edu
    - Ledende efterforsker:
      
      Yifei Zhang
  - Fairfield, Connecticut, Forenede Stater, 06824
    - Rekruttering
    - Smilow Cancer Hospital Care Center-Fairfield
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 203-785-5702
      
      E-mail: canceranswers@yale.edu
    - Ledende efterforsker:
      
      Yifei Zhang
  - Glastonbury, Connecticut, Forenede Stater, 06033
    - Rekruttering
    - Smilow Cancer Hospital Care Center at Glastonbury
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 203-785-5702
      
      E-mail: canceranswers@yale.edu
    - Ledende efterforsker:
      
      Yifei Zhang
  - Greenwich, Connecticut, Forenede Stater, 06830
    - Rekruttering
    - Smilow Cancer Hospital Care Center at Greenwich
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 203-785-5702
      
      E-mail: canceranswers@yale.edu
    - Ledende efterforsker:
      
      Yifei Zhang
  - Guilford, Connecticut, Forenede Stater, 06437
    - Rekruttering
    - Smilow Cancer Hospital Care Center - Guilford
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 203-785-5702
      
      E-mail: canceranswers@yale.edu
    - Ledende efterforsker:
      
      Yifei Zhang
  - Hartford, Connecticut, Forenede Stater, 06105
    - Rekruttering
    - Smilow Cancer Hospital Care Center at Saint Francis
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 203-785-5702
      
      E-mail: canceranswers@yale.edu
    - Ledende efterforsker:
      
      Yifei Zhang
  - New Haven, Connecticut, Forenede Stater, 06520
    - Rekruttering
    - Yale University
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 203-785-5702
      
      E-mail: canceranswers@yale.edu
    - Ledende efterforsker:
      
      Yifei Zhang
  - North Haven, Connecticut, Forenede Stater, 06473
    - Rekruttering
    - Yale-New Haven Hospital North Haven Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 203-785-5702
      
      E-mail: canceranswers@yale.edu
    - Ledende efterforsker:
      
      Yifei Zhang
  - Stamford, Connecticut, Forenede Stater, 06902
    - Rekruttering
    - Smilow Cancer Hospital Care Center at Long Ridge
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 203-785-5702
      
      E-mail: canceranswers@yale.edu
    - Ledende efterforsker:
      
      Yifei Zhang
  - Torrington, Connecticut, Forenede Stater, 06790
    - Rekruttering
    - Smilow Cancer Hospital-Torrington Care Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 203-785-5702
      
      E-mail: canceranswers@yale.edu
    - Ledende efterforsker:
      
      Yifei Zhang
  - Trumbull, Connecticut, Forenede Stater, 06611
    - Rekruttering
    - Smilow Cancer Hospital Care Center-Trumbull
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 203-785-5702
      
      E-mail: canceranswers@yale.edu
    - Ledende efterforsker:
      
      Yifei Zhang
  - Waterbury, Connecticut, Forenede Stater, 06708
    - Rekruttering
    - Smilow Cancer Hospital-Waterbury Care Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 203-785-5702
      
      E-mail: canceranswers@yale.edu
    - Ledende efterforsker:
      
      Yifei Zhang
  - Waterford, Connecticut, Forenede Stater, 06385
    - Rekruttering
    - Smilow Cancer Hospital Care Center - Waterford
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 203-785-5702
      
      E-mail: canceranswers@yale.edu
    - Ledende efterforsker:
      
      Yifei Zhang
- Delaware
  - Millville, Delaware, Forenede Stater, 19967
    - Rekruttering
    - Beebe South Coastal Health Campus
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 302-291-6730
      
      E-mail: research@beebehealthcare.org
    - Ledende efterforsker:
      
      Gregory A. Masters
  - Newark, Delaware, Forenede Stater, 19713
    - Rekruttering
    - Helen F Graham Cancer Center
    - Ledende efterforsker:
      
      Gregory A. Masters
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 302-623-4450
      
      E-mail: lbarone@christianacare.org
  - Newark, Delaware, Forenede Stater, 19713
    - Rekruttering
    - Medical Oncology Hematology Consultants PA
    - Ledende efterforsker:
      
      Gregory A. Masters
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 302-623-4450
      
      E-mail: lbarone@christianacare.org
  - Rehoboth Beach, Delaware, Forenede Stater, 19971
    - Rekruttering
    - Beebe Health Campus
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 302-291-6730
      
      E-mail: research@beebehealthcare.org
    - Ledende efterforsker:
      
      Gregory A. Masters
- District of Columbia
  - Washington D.C., District of Columbia, Forenede Stater, 20007
    - Rekruttering
    - MedStar Georgetown University Hospital
    - Ledende efterforsker:
      
      Marcus S. Noel
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 202-444-2223
- Florida
  - Miami Beach, Florida, Forenede Stater, 33140
    - Rekruttering
    - Mount Sinai Medical Center
    - Ledende efterforsker:
      
      Mike Cusnir
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 305-674-2625
      
      E-mail: Yvonne.Enriquez@msmc.com
  - Orlando, Florida, Forenede Stater, 32803
    - Rekruttering
    - AdventHealth Orlando
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 407-303-2090
      
      E-mail: FH.Cancer.Research@flhosp.org
    - Ledende efterforsker:
      
      Mohamedtaki A. Tejani
- Georgia
  - Atlanta, Georgia, Forenede Stater, 30322
    - Rekruttering
    - Emory University Hospital/Winship Cancer Institute
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 404-778-1868
    - Ledende efterforsker:
      
      Oluwadunni Emiloju
  - Atlanta, Georgia, Forenede Stater, 30308
    - Rekruttering
    - Emory University Hospital Midtown
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 888-946-7447
    - Ledende efterforsker:
      
      Oluwadunni Emiloju
  - Atlanta, Georgia, Forenede Stater, 30342
    - Rekruttering
    - Emory Saint Joseph's Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 404-851-7115
    - Ledende efterforsker:
      
      Oluwadunni Emiloju
  - Decatur, Georgia, Forenede Stater, 30033
    - Rekruttering
    - Emory Decatur Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 440-778-1868
      
      E-mail: clinicaltrialsoncology@dekalbmedical.org
    - Ledende efterforsker:
      
      Oluwadunni Emiloju
  - Johns Creek, Georgia, Forenede Stater, 30097
    - Rekruttering
    - Emory Johns Creek Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 404-778-5714
      
      E-mail: m.lisa.hwang@emory.edu
    - Ledende efterforsker:
      
      Oluwadunni Emiloju
- Hawaii
  - Honolulu, Hawaii, Forenede Stater, 96826
    - Rekruttering
    - Kapiolani Medical Center for Women and Children
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 808-983-6090
    - Ledende efterforsker:
      
      Elizabeth S. Nakasone
  - Honolulu, Hawaii, Forenede Stater, 96813
    - Rekruttering
    - Hawaii Cancer Care Inc - Waterfront Plaza
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 808-524-6115
      
      E-mail: i.webster@hawaiicancercare.com
    - Ledende efterforsker:
      
      Elizabeth S. Nakasone
  - Honolulu, Hawaii, Forenede Stater, 96813
    - Rekruttering
    - Queen's Cancer Cenrer - POB I
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 808-532-0315
    - Ledende efterforsker:
      
      Elizabeth S. Nakasone
  - Honolulu, Hawaii, Forenede Stater, 96813
    - Rekruttering
    - Queen's Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 808-545-8548
    - Ledende efterforsker:
      
      Elizabeth S. Nakasone
  - Honolulu, Hawaii, Forenede Stater, 96813
    - Rekruttering
    - Straub Clinic and Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 808-522-4333
    - Ledende efterforsker:
      
      Elizabeth S. Nakasone
  - Honolulu, Hawaii, Forenede Stater, 96817
    - Rekruttering
    - Queen's Cancer Center - Kuakini
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 808-531-8521
    - Ledende efterforsker:
      
      Elizabeth S. Nakasone
  - Honolulu, Hawaii, Forenede Stater, 96819
    - Rekruttering
    - Kaiser Permanente Moanalua Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 808-432-5195
      
      E-mail: shelley.a.clark@kp.org
    - Ledende efterforsker:
      
      Tilak K. Sundaresan
  - ‘Aiea, Hawaii, Forenede Stater, 96701
    - Rekruttering
    - Hawaii Cancer Care - Westridge
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 808-539-2273
      
      E-mail: info@hawaiicancercare.com
    - Ledende efterforsker:
      
      Elizabeth S. Nakasone
  - ‘Aiea, Hawaii, Forenede Stater, 96701
    - Rekruttering
    - Pali Momi Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 808-486-6000
    - Ledende efterforsker:
      
      Elizabeth S. Nakasone
  - ‘Ewa Beach, Hawaii, Forenede Stater, 96706
    - Rekruttering
    - The Queen's Medical Center - West Oahu
    - Kontakt:
      
      Site Public Contact
      
      E-mail: rohta@queens.org
    - Ledende efterforsker:
      
      Elizabeth S. Nakasone
- Idaho
  - Boise, Idaho, Forenede Stater, 83706
    - Rekruttering
    - Saint Alphonsus Cancer Care Center-Boise
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 734-712-3671
      
      E-mail: stephanie.couch@stjoeshealth.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Caldwell, Idaho, Forenede Stater, 83605
    - Rekruttering
    - Saint Alphonsus Cancer Care Center-Caldwell
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 734-712-3671
      
      E-mail: stephanie.couch@stjoeshealth.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Coeur d'Alene, Idaho, Forenede Stater, 83814
    - Rekruttering
    - Kootenai Health - Coeur d'Alene
    - Ledende efterforsker:
      
      John M. Schallenkamp
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 406-969-6060
      
      E-mail: mccinfo@mtcancer.org
  - Nampa, Idaho, Forenede Stater, 83687
    - Rekruttering
    - Saint Alphonsus Cancer Care Center-Nampa
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 406-969-6060
      
      E-mail: mccinfo@mtcancer.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Post Falls, Idaho, Forenede Stater, 83854
    - Rekruttering
    - Kootenai Clinic Cancer Services - Post Falls
    - Ledende efterforsker:
      
      John M. Schallenkamp
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 406-969-6060
      
      E-mail: mccinfo@mtcancer.org
  - Sandpoint, Idaho, Forenede Stater, 83864
    - Rekruttering
    - Kootenai Clinic Cancer Services - Sandpoint
    - Ledende efterforsker:
      
      John M. Schallenkamp
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 406-969-6060
      
      E-mail: mccinfo@mtcancer.org
- Illinois
  - Aurora, Illinois, Forenede Stater, 60506
    - Rekruttering
    - Advocate Outpatient Center - Aurora
    - Ledende efterforsker:
      
      Edward S. James
    - Kontakt:
      
      Site Public Contact
      
      E-mail: ncorp@aah.org
  - Aurora, Illinois, Forenede Stater, 60504
    - Suspenderet
    - Rush-Copley Medical Center
  - Barrington, Illinois, Forenede Stater, 60010
    - Rekruttering
    - Advocate Good Shepherd Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 847-842-4847
    - Ledende efterforsker:
      
      Edward S. James
  - Bloomington, Illinois, Forenede Stater, 61704
    - Suspenderet
    - Illinois CancerCare-Bloomington
  - Canton, Illinois, Forenede Stater, 61520
    - Suspenderet
    - Illinois CancerCare-Canton
  - Carthage, Illinois, Forenede Stater, 62321
    - Suspenderet
    - Illinois CancerCare-Carthage
  - Chicago, Illinois, Forenede Stater, 60611
    - Rekruttering
    - Northwestern University
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 312-695-1301
      
      E-mail: cancer@northwestern.edu
    - Ledende efterforsker:
      
      Aparna Kalyan
  - Chicago, Illinois, Forenede Stater, 60612
    - Rekruttering
    - University of Illinois
    - Ledende efterforsker:
      
      Yolande Chen
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 312-355-3046
  - Chicago, Illinois, Forenede Stater, 60657
    - Rekruttering
    - Advocate Illinois Masonic Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 773-296-5360
    - Ledende efterforsker:
      
      Edward S. James
  - Chicago, Illinois, Forenede Stater, 60625
    - Rekruttering
    - Swedish Covenant Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 773-878-8200
    - Ledende efterforsker:
      
      Lauren A. Wiebe
  - Chicago, Illinois, Forenede Stater, 60637
    - Aktiv, ikke rekrutterende
    - University of Chicago Comprehensive Cancer Center
  - Chicago, Illinois, Forenede Stater, 60641
    - Rekruttering
    - Northwestern Medicine Cancer Center Old Irving Park
    - Ledende efterforsker:
      
      Aparna Kalyan
    - Kontakt:
      
      Site Public Contact
      
      E-mail: nctnprogram_rhlccc@northwestern.edu
  - Crystal Lake, Illinois, Forenede Stater, 60014
    - Rekruttering
    - AMG Crystal Lake - Oncology
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 630-929-6129
      
      E-mail: advocateresearch@advocate.com
    - Ledende efterforsker:
      
      Edward S. James
  - Danville, Illinois, Forenede Stater, 61832
    - Rekruttering
    - Carle at The Riverfront
    - Ledende efterforsker:
      
      Suparna Mantha
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-446-5532
      
      E-mail: Research@Carle.com
  - DeKalb, Illinois, Forenede Stater, 60115
    - Rekruttering
    - Northwestern Medicine Cancer Center Kishwaukee
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 630-352-5360
      
      E-mail: Donald.Smith3@nm.org
    - Ledende efterforsker:
      
      Aparna Kalyan
  - Decatur, Illinois, Forenede Stater, 62526
    - Rekruttering
    - Cancer Care Specialists of Illinois - Decatur
    - Ledende efterforsker:
      
      Bryan A. Faller
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 217-876-4762
      
      E-mail: morganthaler.jodi@mhsil.com
  - Decatur, Illinois, Forenede Stater, 62526
    - Rekruttering
    - Decatur Memorial Hospital
    - Ledende efterforsker:
      
      Bryan A. Faller
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 217-876-4762
      
      E-mail: morganthaler.jodi@mhsil.com
  - Dixon, Illinois, Forenede Stater, 61021
    - Suspenderet
    - Illinois CancerCare-Dixon
  - Downers Grove, Illinois, Forenede Stater, 60515
    - Rekruttering
    - Advocate Good Samaritan Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 630-275-1270
      
      E-mail: Barbara.barhamand@advocatehealth.com
    - Ledende efterforsker:
      
      Edward S. James
  - Effingham, Illinois, Forenede Stater, 62401
    - Rekruttering
    - Carle Physician Group-Effingham
    - Ledende efterforsker:
      
      Suparna Mantha
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-446-5532
      
      E-mail: Research@carle.com
  - Effingham, Illinois, Forenede Stater, 62401
    - Rekruttering
    - Crossroads Cancer Center
    - Ledende efterforsker:
      
      Bryan A. Faller
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 217-876-4762
      
      E-mail: morganthaler.jodi@mhsil.com
  - Elgin, Illinois, Forenede Stater, 60123
    - Rekruttering
    - Advocate Sherman Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 847-429-2907
    - Ledende efterforsker:
      
      Edward S. James
  - Eureka, Illinois, Forenede Stater, 61530
    - Suspenderet
    - Illinois CancerCare-Eureka
  - Evanston, Illinois, Forenede Stater, 60201
    - Rekruttering
    - NorthShore University HealthSystem-Evanston Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 847-570-2109
    - Ledende efterforsker:
      
      Lauren A. Wiebe
  - Galesburg, Illinois, Forenede Stater, 61401
    - Suspenderet
    - Illinois CancerCare-Galesburg
  - Geneva, Illinois, Forenede Stater, 60134
    - Rekruttering
    - Northwestern Medicine Cancer Center Delnor
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 630-352-5360
      
      E-mail: Donald.Smith3@nm.org
    - Ledende efterforsker:
      
      Aparna Kalyan
  - Glenview, Illinois, Forenede Stater, 60026
    - Rekruttering
    - NorthShore University HealthSystem-Glenbrook Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 847-570-2109
    - Ledende efterforsker:
      
      Lauren A. Wiebe
  - Glenview, Illinois, Forenede Stater, 60026
    - Rekruttering
    - Northwestern Medicine Glenview Outpatient Center
    - Ledende efterforsker:
      
      Aparna Kalyan
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 312-695-1102
  - Grayslake, Illinois, Forenede Stater, 60030
    - Rekruttering
    - Northwestern Medicine Grayslake Outpatient Center
    - Ledende efterforsker:
      
      Aparna Kalyan
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 312-695-1102
  - Harvey, Illinois, Forenede Stater, 60426
    - Aktiv, ikke rekrutterende
    - Ingalls Memorial Hospital
  - Hazel Crest, Illinois, Forenede Stater, 60429
    - Rekruttering
    - Advocate South Suburban Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 708-799-9995
    - Ledende efterforsker:
      
      Edward S. James
  - Highland Park, Illinois, Forenede Stater, 60035
    - Rekruttering
    - NorthShore University HealthSystem-Highland Park Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 847-570-2109
    - Ledende efterforsker:
      
      Lauren A. Wiebe
  - Kewanee, Illinois, Forenede Stater, 61443
    - Suspenderet
    - Illinois CancerCare-Kewanee Clinic
  - Lake Forest, Illinois, Forenede Stater, 60045
    - Rekruttering
    - Northwestern Medicine Lake Forest Hospital
    - Kontakt:
      
      Site Public Contact
      
      E-mail: cancertrials@northwestern.edu
    - Ledende efterforsker:
      
      Aparna Kalyan
  - Libertyville, Illinois, Forenede Stater, 60048
    - Rekruttering
    - AMG Libertyville - Oncology
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 630-929-6129
      
      E-mail: advocateresearch@advocatehealth.com
    - Ledende efterforsker:
      
      Edward S. James
  - Libertyville, Illinois, Forenede Stater, 60048
    - Rekruttering
    - Condell Memorial Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 630-929-6129
      
      E-mail: advocateresearch@advocatehealth.com
    - Ledende efterforsker:
      
      Edward S. James
  - Macomb, Illinois, Forenede Stater, 61455
    - Suspenderet
    - Illinois CancerCare-Macomb
  - Mattoon, Illinois, Forenede Stater, 61938
    - Rekruttering
    - Carle Physician Group-Mattoon/Charleston
    - Ledende efterforsker:
      
      Suparna Mantha
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-446-5532
      
      E-mail: Research@carle.com
  - New Lenox, Illinois, Forenede Stater, 60451
    - Aktiv, ikke rekrutterende
    - UC Comprehensive Cancer Center at Silver Cross
  - O'Fallon, Illinois, Forenede Stater, 62269
    - Rekruttering
    - Cancer Care Center of O'Fallon
    - Ledende efterforsker:
      
      Bryan A. Faller
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 217-876-4762
      
      E-mail: morganthaler.jodi@mhsil.com
  - Oak Brook, Illinois, Forenede Stater, 60523
    - Rekruttering
    - Northwestern Medicine Oak Brook
    - Ledende efterforsker:
      
      Aparna Kalyan
    - Kontakt:
      
      Site Public Contact
      
      E-mail: nctnprogram_rhlccc@northwestern.edu
  - Oak Lawn, Illinois, Forenede Stater, 60453-2699
    - Rekruttering
    - Advocate Christ Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-323-8622
    - Ledende efterforsker:
      
      Edward S. James
  - Orland Park, Illinois, Forenede Stater, 60462
    - Aktiv, ikke rekrutterende
    - University of Chicago Medicine-Orland Park
  - Orland Park, Illinois, Forenede Stater, 60462
    - Rekruttering
    - Northwestern Medicine Orland Park
    - Ledende efterforsker:
      
      Aparna Kalyan
    - Kontakt:
      
      Site Public Contact
      
      E-mail: nctnprogram_rhlccc@northwestern.edu
  - Ottawa, Illinois, Forenede Stater, 61350
    - Suspenderet
    - Illinois CancerCare-Ottawa Clinic
  - Park Ridge, Illinois, Forenede Stater, 60068
    - Rekruttering
    - Advocate Lutheran General Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 847-384-3621
    - Ledende efterforsker:
      
      Edward S. James
  - Pekin, Illinois, Forenede Stater, 61554
    - Suspenderet
    - Illinois CancerCare-Pekin
  - Peoria, Illinois, Forenede Stater, 61615
    - Suspenderet
    - Illinois CancerCare-Peoria
  - Peru, Illinois, Forenede Stater, 61354
    - Suspenderet
    - Illinois CancerCare-Peru
  - Princeton, Illinois, Forenede Stater, 61356
    - Suspenderet
    - Illinois CancerCare-Princeton
  - Rockford, Illinois, Forenede Stater, 61114
    - Rekruttering
    - UW Health Carbone Cancer Center Rockford
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 779-696-9378
      
      E-mail: lkline@uwhealth.org
    - Ledende efterforsker:
      
      Fahrettin Covut
  - Rockford, Illinois, Forenede Stater, 61114
    - Rekruttering
    - Mercyhealth Cancer Institute - Rockford
    - Ledende efterforsker:
      
      Mayur Narkhede
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 815-971-5858
      
      E-mail: oncologyclinicaltrials@mhemail.org
  - Shiloh, Illinois, Forenede Stater, 62269
    - Rekruttering
    - Memorial Hospital East
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 314-747-9912
      
      E-mail: dschwab@wustl.edu
    - Ledende efterforsker:
      
      Patrick Grierson
  - Springfield, Illinois, Forenede Stater, 62702
    - Rekruttering
    - Southern Illinois University School of Medicine
    - Ledende efterforsker:
      
      Bryan A. Faller
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 217-545-7929
  - Springfield, Illinois, Forenede Stater, 62702
    - Rekruttering
    - Springfield Clinic
    - Ledende efterforsker:
      
      Bryan A. Faller
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-444-7541
  - Springfield, Illinois, Forenede Stater, 62781
    - Rekruttering
    - Springfield Memorial Hospital
    - Ledende efterforsker:
      
      Bryan A. Faller
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 217-528-7541
      
      E-mail: pallante.beth@mhsil.com
  - Urbana, Illinois, Forenede Stater, 61801
    - Rekruttering
    - Carle Cancer Center
    - Ledende efterforsker:
      
      Suparna Mantha
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-446-5532
      
      E-mail: Research@carle.com
  - Warrenville, Illinois, Forenede Stater, 60555
    - Rekruttering
    - Northwestern Medicine Cancer Center Warrenville
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 630-352-5360
      
      E-mail: Donald.Smith3@nm.org
    - Ledende efterforsker:
      
      Aparna Kalyan
  - Washington, Illinois, Forenede Stater, 61571
    - Suspenderet
    - Illinois CancerCare - Washington
- Indiana
  - Crown Point, Indiana, Forenede Stater, 46307
    - Aktiv, ikke rekrutterende
    - UChicago Medicine Northwest Indiana
  - Crown Point, Indiana, Forenede Stater, 46307
    - Rekruttering
    - Northwest Cancer Center - Crown Point
    - Ledende efterforsker:
      
      Suparna Mantha
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 219-836-6879
      
      E-mail: CancerResearch@powershealth.org
  - Dyer, Indiana, Forenede Stater, 46311
    - Rekruttering
    - Northwest Oncology LLC
    - Ledende efterforsker:
      
      Suparna Mantha
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 219-924-8178
  - Hobart, Indiana, Forenede Stater, 46342
    - Rekruttering
    - Northwest Cancer Center - Hobart
    - Ledende efterforsker:
      
      Suparna Mantha
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 219-947-1795
  - Hobart, Indiana, Forenede Stater, 46342
    - Rekruttering
    - Saint Mary Medical Center
    - Ledende efterforsker:
      
      Suparna Mantha
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 219-836-6875
      
      E-mail: CancerResearch@COMHS.org
  - Indianapolis, Indiana, Forenede Stater, 46312
    - Rekruttering
    - Saint Catherine Hospital
    - Ledende efterforsker:
      
      Suparna Mantha
    - Kontakt:
      
      Site Public Contact
      
      E-mail: protocols@swog.org
  - Munster, Indiana, Forenede Stater, 46321
    - Rekruttering
    - The Community Hospital
    - Ledende efterforsker:
      
      Suparna Mantha
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 219-836-3349
  - Munster, Indiana, Forenede Stater, 46321
    - Rekruttering
    - Women's Diagnostic Center - Munster
    - Ledende efterforsker:
      
      Suparna Mantha
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 219-934-8869
      
      E-mail: mnicholson@comhs.org
  - Valparaiso, Indiana, Forenede Stater, 46383
    - Rekruttering
    - Northwest Cancer Center - Valparaiso
    - Ledende efterforsker:
      
      Suparna Mantha
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 219-836-6875
      
      E-mail: CancerResearch@COMHS.org
- Iowa
  - Ankeny, Iowa, Forenede Stater, 50023
    - Rekruttering
    - UI Health Care Mission Cancer and Blood - Ankeny Clinic
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 515-241-3305
    - Ledende efterforsker:
      
      Seema Harichand-Herdt
  - Carroll, Iowa, Forenede Stater, 51401
    - Rekruttering
    - Saint Anthony Regional Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 515-689-7658
      
      E-mail: sbenson@iora.org
    - Ledende efterforsker:
      
      Seema Harichand-Herdt
  - Cedar Rapids, Iowa, Forenede Stater, 52403
    - Rekruttering
    - Mercy Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 319-365-4673
    - Ledende efterforsker:
      
      Deborah W. Wilbur
  - Cedar Rapids, Iowa, Forenede Stater, 52403
    - Rekruttering
    - Oncology Associates at Mercy Medical Center
    - Ledende efterforsker:
      
      Deborah W. Wilbur
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 319-363-2690
  - Clive, Iowa, Forenede Stater, 50325
    - Rekruttering
    - UI Health Care Mission Cancer and Blood - West Des Moines Clinic
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 515-241-3305
    - Ledende efterforsker:
      
      Seema Harichand-Herdt
  - Des Moines, Iowa, Forenede Stater, 50314
    - Rekruttering
    - Broadlawns Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 515-282-2200
    - Ledende efterforsker:
      
      Seema Harichand-Herdt
  - Des Moines, Iowa, Forenede Stater, 50309
    - Rekruttering
    - Iowa Methodist Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 515-241-6727
    - Ledende efterforsker:
      
      Seema Harichand-Herdt
  - Des Moines, Iowa, Forenede Stater, 50309
    - Rekruttering
    - UI Health Care Mission Cancer and Blood - Des Moines Clinic
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 515-241-3305
    - Ledende efterforsker:
      
      Seema Harichand-Herdt
  - Des Moines, Iowa, Forenede Stater, 50314
    - Rekruttering
    - UI Health Care Mission Cancer and Blood - Laurel Clinic
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 515-241-3305
    - Ledende efterforsker:
      
      Seema Harichand-Herdt
  - Fort Dodge, Iowa, Forenede Stater, 50501
    - Rekruttering
    - UI Healthcare Mission Cancer and Blood - Fort Dodge
    - Ledende efterforsker:
      
      Seema Harichand-Herdt
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 515-282-2921
      
      E-mail: trials@missioncancer.com
  - Waukee, Iowa, Forenede Stater, 50263
    - Rekruttering
    - UI Health Care Mission Cancer and Blood - Waukee Clinic
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 515-241-3305
    - Ledende efterforsker:
      
      Seema Harichand-Herdt
- Kansas
  - Hays, Kansas, Forenede Stater, 67601
    - Rekruttering
    - HaysMed
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 785-623-5774
    - Ledende efterforsker:
      
      Gary C. Doolittle
  - Lawrence, Kansas, Forenede Stater, 66044
    - Rekruttering
    - Lawrence Memorial Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 785-505-2800
      
      E-mail: Stephanie.Norris@LMH.ORG
    - Ledende efterforsker:
      
      Gary C. Doolittle
  - Olathe, Kansas, Forenede Stater, 66061
    - Rekruttering
    - The University of Kansas Cancer Center - Olathe
    - Ledende efterforsker:
      
      Gary C. Doolittle
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 913-588-1569
      
      E-mail: OlatheCCResearch@kumc.edu
  - Salina, Kansas, Forenede Stater, 67401
    - Rekruttering
    - Salina Regional Health Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 785-452-7038
      
      E-mail: mleepers@srhc.com
    - Ledende efterforsker:
      
      Gary C. Doolittle
  - Topeka, Kansas, Forenede Stater, 66606
    - Rekruttering
    - University of Kansas Health System Saint Francis Campus
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 785-295-8000
    - Ledende efterforsker:
      
      Gary C. Doolittle
- Kentucky
  - Lexington, Kentucky, Forenede Stater, 40509
    - Aktiv, ikke rekrutterende
    - CommonSpirit Saint Joseph Medical Center - East Lexington
- Louisiana
  - Covington, Louisiana, Forenede Stater, 70433
    - Rekruttering
    - Ochsner Hematology Oncology North Shore - Covington (West Region)
    - Ledende efterforsker:
      
      Jonathan D. Mizrahi
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 985-809-5668
      
      E-mail: Cheryl.kesler@ochsner.org
  - New Orleans, Louisiana, Forenede Stater, 70121
    - Rekruttering
    - Ochsner Medical Center Jefferson
    - Ledende efterforsker:
      
      Jonathan D. Mizrahi
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 504-842-8084
      
      E-mail: Elisemarie.curry@ochsner.org
- Maryland
  - Cumberland, Maryland, Forenede Stater, 21502
    - Rekruttering
    - UPMC Western Maryland
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 240-964-1400
    - Ledende efterforsker:
      
      Anwaar Saeed
- Michigan
  - Ann Arbor, Michigan, Forenede Stater, 48106
    - Rekruttering
    - Trinity Health Saint Joseph Mercy Hospital Ann Arbor
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 734-712-7251
      
      E-mail: MCRCwebsitecontactform@stjoeshealth.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Brighton, Michigan, Forenede Stater, 48114
    - Rekruttering
    - Trinity Health IHA Medical Group Hematology Oncology - Brighton
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 734-712-7251
      
      E-mail: MCRCwebsitecontactform@stjoeshealth.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Brighton, Michigan, Forenede Stater, 48114
    - Rekruttering
    - Trinity Health Medical Center - Brighton
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 734-712-7251
      
      E-mail: MCRCwebsitecontactform@stjoeshealth.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Brownstown, Michigan, Forenede Stater, 48183
    - Rekruttering
    - Henry Ford Cancer Institute-Downriver
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 313-916-3721
      
      E-mail: CTOResearch@hfhs.org
    - Ledende efterforsker:
      
      Gazala Khan
  - Canton, Michigan, Forenede Stater, 48188
    - Rekruttering
    - Trinity Health IHA Medical Group Hematology Oncology - Canton
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 734-712-7251
      
      E-mail: MCRCwebsitecontactform@stjoeshealth.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Canton, Michigan, Forenede Stater, 48188
    - Rekruttering
    - Trinity Health Medical Center - Canton
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 734-712-7251
      
      E-mail: MCRCwebsitecontactform@stjoeshealth.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Chelsea, Michigan, Forenede Stater, 48118
    - Rekruttering
    - Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 734-712-7251
      
      E-mail: MCRCwebsitecontactform@stjoeshealth.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Chelsea, Michigan, Forenede Stater, 48118
    - Rekruttering
    - Chelsea Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 734-712-7251
      
      E-mail: MCRCwebsitecontactform@stjoeshealth.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Clinton Township, Michigan, Forenede Stater, 48038
    - Rekruttering
    - Henry Ford Macomb Hospital-Clinton Township
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 313-916-3721
      
      E-mail: CTOResearch@hfhs.org
    - Ledende efterforsker:
      
      Gazala Khan
  - Dearborn, Michigan, Forenede Stater, 48126
    - Rekruttering
    - Henry Ford Medical Center-Fairlane
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 313-916-3721
      
      E-mail: CTOResearch@hfhs.org
    - Ledende efterforsker:
      
      Gazala Khan
  - Detroit, Michigan, Forenede Stater, 48202
    - Rekruttering
    - Henry Ford Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 313-916-3721
      
      E-mail: CTOResearch@hfhs.org
    - Ledende efterforsker:
      
      Gazala Khan
  - Escanaba, Michigan, Forenede Stater, 49829
    - Rekruttering
    - OSF Saint Francis Hospital and Medical Group
    - Ledende efterforsker:
      
      Matthew L. Ryan
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 920-433-8889
      
      E-mail: WI_research_admin@hshs.org
  - Flint, Michigan, Forenede Stater, 48503
    - Rekruttering
    - Genesys Hurley Cancer Institute
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 810-762-8038
      
      E-mail: wstrong@ghci.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Flint, Michigan, Forenede Stater, 48503
    - Rekruttering
    - Hurley Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 810-762-8038
      
      E-mail: wstrong@ghci.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Flint, Michigan, Forenede Stater, 48503
    - Suspenderet
    - Genesee Hematology Oncology PC
  - Flint, Michigan, Forenede Stater, 48503
    - Rekruttering
    - Cancer Hematology Centers - Flint
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 810-762-8038
      
      E-mail: wstrong@ghci.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Jackson, Michigan, Forenede Stater, 49201
    - Rekruttering
    - Allegiance Health
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 313-916-3721
      
      E-mail: CTOResearch@hfhs.org
    - Ledende efterforsker:
      
      Gazala Khan
  - Lansing, Michigan, Forenede Stater, 48912
    - Rekruttering
    - University of Michigan Health - Sparrow Lansing
    - Ledende efterforsker:
      
      Tareq Al baghdadi
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 517-364-3712
      
      E-mail: harsha.trivedi@umhsparrow.org
  - Livonia, Michigan, Forenede Stater, 48154
    - Rekruttering
    - Trinity Health Saint Mary Mercy Livonia Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 734-712-7251
      
      E-mail: MCRCwebsitecontactform@stjoeshealth.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Novi, Michigan, Forenede Stater, 48377
    - Rekruttering
    - Henry Ford Medical Center-Columbus
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 313-916-3721
      
      E-mail: CTOResearch@hfhs.org
    - Ledende efterforsker:
      
      Gazala Khan
  - Novi, Michigan, Forenede Stater, 48374
    - Suspenderet
    - Henry Ford Health Providence Novi Hospital
  - Pontiac, Michigan, Forenede Stater, 48341
    - Rekruttering
    - Trinity Health Saint Joseph Mercy Oakland Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 734-712-7251
      
      E-mail: MCRCwebsitecontactform@stjoeshealth.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Southfield, Michigan, Forenede Stater, 48075
    - Suspenderet
    - Henry Ford Health Providence Southfield Hospital
  - West Bloomfield, Michigan, Forenede Stater, 48322
    - Rekruttering
    - Henry Ford West Bloomfield Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 313-916-3721
      
      E-mail: CTOResearch@hfhs.org
    - Ledende efterforsker:
      
      Gazala Khan
  - Wyandotte, Michigan, Forenede Stater, 48192
    - Rekruttering
    - Henry Ford Wyandotte Hospital
    - Kontakt:
      
      Site Public Contact
      
      E-mail: nhay@hfhs.org
    - Ledende efterforsker:
      
      Gazala Khan
  - Ypsilanti, Michigan, Forenede Stater, 48197
    - Rekruttering
    - Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 734-712-7251
      
      E-mail: MCRCwebsitecontactform@stjoeshealth.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
- Minnesota
  - Bemidji, Minnesota, Forenede Stater, 56601
    - Rekruttering
    - Sanford Joe Lueken Cancer Center
    - Ledende efterforsker:
      
      Daniel Almquist
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 218-333-5000
      
      E-mail: OncologyClinicalTrialsFargo@sanfordhealth.org
  - Brainerd, Minnesota, Forenede Stater, 56401
    - Rekruttering
    - Essentia Health Saint Joseph's Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 218-786-3308
      
      E-mail: CancerTrials@EssentiaHealth.org
    - Ledende efterforsker:
      
      Bret E. Friday
  - Coon Rapids, Minnesota, Forenede Stater, 55433
    - Rekruttering
    - Mercy Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 952-993-1517
      
      E-mail: mmcorc@healthpartners.com
    - Ledende efterforsker:
      
      David M. King
  - Deer River, Minnesota, Forenede Stater, 56636
    - Rekruttering
    - Essentia Health - Deer River Clinic
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 218-786-3308
      
      E-mail: CancerTrials@EssentiaHealth.org
    - Ledende efterforsker:
      
      Bret E. Friday
  - Duluth, Minnesota, Forenede Stater, 55805
    - Rekruttering
    - Essentia Health Cancer Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 218-786-3308
      
      E-mail: CancerTrials@EssentiaHealth.org
    - Ledende efterforsker:
      
      Bret E. Friday
  - Edina, Minnesota, Forenede Stater, 55435
    - Rekruttering
    - Fairview Southdale Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 952-993-1517
      
      E-mail: mmcorc@healthpartners.com
    - Ledende efterforsker:
      
      David M. King
  - Edina, Minnesota, Forenede Stater, 55435
    - Rekruttering
    - Minnesota Oncology - Edina
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 952-993-1517
      
      E-mail: mmcorc@healthpartners.com
    - Ledende efterforsker:
      
      David M. King
  - Hibbing, Minnesota, Forenede Stater, 55746
    - Rekruttering
    - Essentia Health Hibbing Clinic
    - Ledende efterforsker:
      
      Bret E. Friday
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 218-786-3308
  - Maplewood, Minnesota, Forenede Stater, 55109
    - Rekruttering
    - Saint John's Hospital - Healtheast
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 952-993-1517
      
      E-mail: mmcorc@healthpartners.com
    - Ledende efterforsker:
      
      David M. King
  - Minneapolis, Minnesota, Forenede Stater, 55407
    - Rekruttering
    - Abbott-Northwestern Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 952-993-1517
      
      E-mail: mmcorc@healthpartners.com
    - Ledende efterforsker:
      
      David M. King
  - Saint Louis Park, Minnesota, Forenede Stater, 55416
    - Rekruttering
    - Park Nicollet Clinic - Saint Louis Park
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 952-993-1517
      
      E-mail: mmcorc@healthpartners.com
    - Ledende efterforsker:
      
      David M. King
  - Saint Paul, Minnesota, Forenede Stater, 55101
    - Rekruttering
    - Regions Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 952-993-1517
      
      E-mail: mmcorc@healthpartners.com
    - Ledende efterforsker:
      
      David M. King
  - Saint Paul, Minnesota, Forenede Stater, 55102
    - Rekruttering
    - United Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 952-993-1517
      
      E-mail: mmcorc@healthpartners.com
    - Ledende efterforsker:
      
      David M. King
  - Sandstone, Minnesota, Forenede Stater, 55072
    - Rekruttering
    - Essentia Health Sandstone
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 218-786-3308
      
      E-mail: CancerTrials@EssentiaHealth.org
    - Ledende efterforsker:
      
      Bret E. Friday
  - Virginia, Minnesota, Forenede Stater, 55792
    - Rekruttering
    - Essentia Health Virginia Clinic
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 218-786-3308
      
      E-mail: CancerTrials@EssentiaHealth.org
    - Ledende efterforsker:
      
      Bret E. Friday
  - Woodbury, Minnesota, Forenede Stater, 55125
    - Rekruttering
    - Minnesota Oncology Hematology PA-Woodbury
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 952-993-1517
      
      E-mail: mmcorc@healthpartners.com
    - Ledende efterforsker:
      
      David M. King
- Missouri
  - Cape Girardeau, Missouri, Forenede Stater, 63703
    - Rekruttering
    - Saint Francis Medical Center
    - Ledende efterforsker:
      
      Bryan A. Faller
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 573-334-2230
      
      E-mail: sfmc@sfmc.net
  - City of Saint Peters, Missouri, Forenede Stater, 63376
    - Rekruttering
    - Siteman Cancer Center at Saint Peters Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-600-3606
      
      E-mail: info@siteman.wustl.edu
    - Ledende efterforsker:
      
      Patrick Grierson
  - Creve Coeur, Missouri, Forenede Stater, 63141
    - Rekruttering
    - Siteman Cancer Center at West County Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-600-3606
      
      E-mail: info@siteman.wustl.edu
    - Ledende efterforsker:
      
      Patrick Grierson
  - Kansas City, Missouri, Forenede Stater, 64108
    - Rekruttering
    - University Health Truman Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 816-404-4375
    - Ledende efterforsker:
      
      Gary C. Doolittle
  - St Louis, Missouri, Forenede Stater, 63110
    - Rekruttering
    - Washington University School of Medicine
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-600-3606
      
      E-mail: info@siteman.wustl.edu
    - Ledende efterforsker:
      
      Patrick Grierson
  - St Louis, Missouri, Forenede Stater, 63129
    - Rekruttering
    - Siteman Cancer Center-South County
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-600-3606
      
      E-mail: info@siteman.wustl.edu
    - Ledende efterforsker:
      
      Patrick Grierson
  - St Louis, Missouri, Forenede Stater, 63136
    - Rekruttering
    - Siteman Cancer Center at Christian Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-600-3606
      
      E-mail: info@siteman.wustl.edu
    - Ledende efterforsker:
      
      Patrick Grierson
- Montana
  - Anaconda, Montana, Forenede Stater, 59711
    - Rekruttering
    - Community Hospital of Anaconda
    - Ledende efterforsker:
      
      John M. Schallenkamp
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 406-969-6060
      
      E-mail: mccinfo@mtcancer.org
  - Billings, Montana, Forenede Stater, 59101
    - Rekruttering
    - Billings Clinic Cancer Center
    - Ledende efterforsker:
      
      John M. Schallenkamp
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-996-2663
      
      E-mail: research@billingsclinic.org
  - Billings, Montana, Forenede Stater, 59102
    - Rekruttering
    - Saint Vincent Frontier Cancer Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-648-6274
    - Ledende efterforsker:
      
      Patrick W. Cobb
  - Bozeman, Montana, Forenede Stater, 59715
    - Rekruttering
    - Bozeman Health Deaconess Hospital
    - Ledende efterforsker:
      
      John M. Schallenkamp
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 406-969-6060
      
      E-mail: mccinfo@mtcancer.org
  - Great Falls, Montana, Forenede Stater, 59405
    - Rekruttering
    - Benefis Sletten Cancer Institute
    - Ledende efterforsker:
      
      John M. Schallenkamp
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 406-969-6060
      
      E-mail: mccinfo@mtcancer.org
  - Kalispell, Montana, Forenede Stater, 59901
    - Rekruttering
    - Logan Health Medical Center
    - Ledende efterforsker:
      
      John M. Schallenkamp
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 406-969-6060
      
      E-mail: mccinfo@mtcancer.org
  - Missoula, Montana, Forenede Stater, 59804
    - Rekruttering
    - Community Medical Center
    - Ledende efterforsker:
      
      John M. Schallenkamp
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 406-969-6060
      
      E-mail: mccinfo@mtcancer.org
- Nebraska
  - Bellevue, Nebraska, Forenede Stater, 68123
    - Rekruttering
    - Nebraska Medicine-Bellevue
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 402-559-6941
      
      E-mail: unmcrsa@unmc.edu
    - Ledende efterforsker:
      
      Mridula Krishnan
  - Omaha, Nebraska, Forenede Stater, 68198
    - Rekruttering
    - University of Nebraska Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 402-559-6941
      
      E-mail: unmcrsa@unmc.edu
    - Ledende efterforsker:
      
      Mridula Krishnan
  - Omaha, Nebraska, Forenede Stater, 68118
    - Rekruttering
    - Nebraska Medicine-Village Pointe
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 402-559-5600
    - Ledende efterforsker:
      
      Mridula Krishnan
- Nevada
  - Las Vegas, Nevada, Forenede Stater, 89102
    - Suspenderet
    - OptumCare Cancer Care at Charleston
  - Las Vegas, Nevada, Forenede Stater, 89183
    - Suspenderet
    - OptumCare Cancer Care at Fort Apache
  - Reno, Nevada, Forenede Stater, 89502
    - Suspenderet
    - Renown Regional Medical Center
- New Jersey
  - Cherry Hill, New Jersey, Forenede Stater, 08002
    - Rekruttering
    - Jefferson Cherry Hill Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 215-600-9151
      
      E-mail: ONCTrialNow@jefferson.edu
    - Ledende efterforsker:
      
      Daniel Lin
  - Englewood, New Jersey, Forenede Stater, 07631
    - Aktiv, ikke rekrutterende
    - Englewood Hospital and Medical Center
  - Sewell, New Jersey, Forenede Stater, 08080
    - Rekruttering
    - Sidney Kimmel Cancer Center Washington Township
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 215-600-9151
      
      E-mail: ONCTrialNow@jefferson.edu
    - Ledende efterforsker:
      
      Daniel Lin
- New Mexico
  - Albuquerque, New Mexico, Forenede Stater, 87102
    - Rekruttering
    - Lovelace Medical Center-Saint Joseph Square
    - Ledende efterforsker:
      
      Jessica Belmonte
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 505-272-0530
      
      E-mail: ZPollock@salud.unm.edu
  - Albuquerque, New Mexico, Forenede Stater, 87106
    - Rekruttering
    - University of New Mexico Cancer Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 505-925-0348
      
      E-mail: HSC-ClinicalTrialInfo@salud.unm.edu
    - Ledende efterforsker:
      
      Jessica Belmonte
- New York
  - Bay Shore, New York, Forenede Stater, 11706
    - Rekruttering
    - Northwell Health Imbert Cancer Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 516-734-8896
    - Ledende efterforsker:
      
      Crystal Antoine-Pepeljugoski
  - Buffalo, New York, Forenede Stater, 14263
    - Rekruttering
    - Roswell Park Cancer Institute
    - Ledende efterforsker:
      
      Kannan Thanikachalam
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-767-9355
      
      E-mail: askroswell@roswellpark.org
  - Glens Falls, New York, Forenede Stater, 12801
    - Aktiv, ikke rekrutterende
    - Glens Falls Hospital
  - Greenlawn, New York, Forenede Stater, 11740
    - Rekruttering
    - Northwell Health Cancer Institute at Huntington
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 516-734-8896
    - Ledende efterforsker:
      
      Crystal Antoine-Pepeljugoski
  - Lake Success, New York, Forenede Stater, 11042
    - Rekruttering
    - Northwell Health/Center for Advanced Medicine
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 516-734-8896
    - Ledende efterforsker:
      
      Crystal Antoine-Pepeljugoski
  - Mineola, New York, Forenede Stater, 11501
    - Rekruttering
    - NYU Langone Hospital - Long Island
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 212-263-4432
      
      E-mail: cancertrials@nyulangone.org
    - Ledende efterforsker:
      
      Jennifer W. Chuy
  - Mount Kisco, New York, Forenede Stater, 10549
    - Rekruttering
    - Northern Westchester Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 914-666-1366
      
      E-mail: AMellor@northwell.edu
    - Ledende efterforsker:
      
      Crystal Antoine-Pepeljugoski
  - New York, New York, Forenede Stater, 10016
    - Rekruttering
    - Laura and Isaac Perlmutter Cancer Center at NYU Langone
    - Kontakt:
      
      Site Public Contact
      
      E-mail: CancerTrials@nyulangone.org
    - Ledende efterforsker:
      
      Jennifer W. Chuy
  - Rochester, New York, Forenede Stater, 14642
    - Rekruttering
    - University of Rochester
    - Ledende efterforsker:
      
      Richard F. Dunne
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 585-275-5830
  - Sleepy Hollow, New York, Forenede Stater, 10591
    - Rekruttering
    - Phelps Memorial Hospital Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 914-366-1600
    - Ledende efterforsker:
      
      Crystal Antoine-Pepeljugoski
  - Williamsville, New York, Forenede Stater, 14221
    - Rekruttering
    - Roswell Park Amherst Center
    - Ledende efterforsker:
      
      Kannan Thanikachalam
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-767-9355
      
      E-mail: askroswell@roswellpark.org
- North Carolina
  - Asheboro, North Carolina, Forenede Stater, 27203
    - Suspenderet
    - Cone Health Cancer Center at Asheboro
  - Asheboro, North Carolina, Forenede Stater, 27205
    - Rekruttering
    - Cone Health MedCenter Asheboro
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 336-832-0836
      
      E-mail: stacey.phelps@conehealth.com
    - Ledende efterforsker:
      
      Vinay K. Gudena
  - Burlington, North Carolina, Forenede Stater, 27215
    - Rekruttering
    - Cone Health Cancer Center at Alamance Regional
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 336-832-0836
      
      E-mail: stacey.phelps@conehealth.com
    - Ledende efterforsker:
      
      Vinay K. Gudena
  - Clinton, North Carolina, Forenede Stater, 28328
    - Rekruttering
    - Southeastern Medical Oncology Center-Clinton
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 919-587-9084
      
      E-mail: jfields@cancersmoc.com
    - Ledende efterforsker:
      
      Samer S. Kasbari
  - Goldsboro, North Carolina, Forenede Stater, 27534
    - Rekruttering
    - Southeastern Medical Oncology Center-Goldsboro
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 919-587-9084
      
      E-mail: jfields@cancersmoc.com
    - Ledende efterforsker:
      
      Samer S. Kasbari
  - Greensboro, North Carolina, Forenede Stater, 27403
    - Rekruttering
    - Cone Health Cancer Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 336-832-0836
      
      E-mail: stacey.phelps@conehealth.com
    - Ledende efterforsker:
      
      Vinay K. Gudena
  - Greensboro, North Carolina, Forenede Stater, 27410
    - Rekruttering
    - Cone Health Cancer Center at Drawbridge Parkway
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 336-832-0836
      
      E-mail: stacey.phelps@conehealth.com
    - Ledende efterforsker:
      
      Vinay K. Gudena
  - Jacksonville, North Carolina, Forenede Stater, 28546
    - Rekruttering
    - Southeastern Medical Oncology Center-Jacksonville
    - Ledende efterforsker:
      
      Samer S. Kasbari
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 910-587-9084
      
      E-mail: jfields@cancersmoc.com
  - Pinehurst, North Carolina, Forenede Stater, 28374
    - Rekruttering
    - FirstHealth of the Carolinas-Moore Regional Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 910-715-3500
      
      E-mail: jcwilliams@firsthealth.org
    - Ledende efterforsker:
      
      Charles S. Kuzma
  - Reidsville, North Carolina, Forenede Stater, 27320
    - Rekruttering
    - Annie Penn Memorial Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 336-832-0836
      
      E-mail: stacey.phelps@conehealth.com
    - Ledende efterforsker:
      
      Vinay K. Gudena
- North Dakota
  - Bismarck, North Dakota, Forenede Stater, 58501
    - Rekruttering
    - Sanford Bismarck Medical Center
    - Ledende efterforsker:
      
      Daniel Almquist
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 701-323-5760
      
      E-mail: OncologyClinicalTrialsFargo@sanfordhealth.org
  - Fargo, North Dakota, Forenede Stater, 58122
    - Rekruttering
    - Sanford Broadway Medical Center
    - Ledende efterforsker:
      
      Daniel Almquist
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 701-323-5760
      
      E-mail: OncologyClinicalTrialsFargo@sanfordhealth.org
  - Fargo, North Dakota, Forenede Stater, 58103
    - Rekruttering
    - Essentia Health Cancer Center-South University Clinic
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 218-786-3308
      
      E-mail: CancerTrials@EssentiaHealth.org
    - Ledende efterforsker:
      
      Bret E. Friday
  - Fargo, North Dakota, Forenede Stater, 58122
    - Rekruttering
    - Sanford Roger Maris Cancer Center
    - Ledende efterforsker:
      
      Daniel Almquist
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 701-234-6161
      
      E-mail: OncologyClinicalTrialsFargo@sanfordhealth.org
- Ohio
  - Centerville, Ohio, Forenede Stater, 45459
    - Rekruttering
    - Miami Valley Hospital South
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 937-528-2900
      
      E-mail: clinical.trials@daytonncorp.org
    - Ledende efterforsker:
      
      Tarek M. Sabagh
  - Cincinnati, Ohio, Forenede Stater, 45220
    - Aktiv, ikke rekrutterende
    - Good Samaritan Hospital - Cincinnati
  - Dayton, Ohio, Forenede Stater, 45409
    - Rekruttering
    - Miami Valley Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 937-528-2900
      
      E-mail: clinical.trials@daytonncorp.org
    - Ledende efterforsker:
      
      Tarek M. Sabagh
  - Dayton, Ohio, Forenede Stater, 45415
    - Rekruttering
    - Miami Valley Hospital North
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 937-528-2900
      
      E-mail: clinical.trials@daytonncorp.org
    - Ledende efterforsker:
      
      Tarek M. Sabagh
  - Dayton, Ohio, Forenede Stater, 45409
    - Rekruttering
    - Premier Blood and Cancer Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 937-276-8320
    - Ledende efterforsker:
      
      Tarek M. Sabagh
  - Franklin, Ohio, Forenede Stater, 45005-1066
    - Rekruttering
    - Atrium Medical Center-Middletown Regional Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 937-528-2900
      
      E-mail: clinical.trials@daytonncorp.org
    - Ledende efterforsker:
      
      Tarek M. Sabagh
  - Greenville, Ohio, Forenede Stater, 45331
    - Rekruttering
    - Miami Valley Cancer Care and Infusion
    - Ledende efterforsker:
      
      Tarek M. Sabagh
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 937-569-7515
  - Troy, Ohio, Forenede Stater, 45373
    - Rekruttering
    - Upper Valley Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 937-528-2900
      
      E-mail: clinical.trials@daytonncorp.org
    - Ledende efterforsker:
      
      Tarek M. Sabagh
- Oklahoma
  - Lawton, Oklahoma, Forenede Stater, 73505
    - Rekruttering
    - Cancer Centers of Southwest Oklahoma Research
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-231-4440
    - Ledende efterforsker:
      
      Hassan Hatoum
  - Oklahoma City, Oklahoma, Forenede Stater, 73104
    - Rekruttering
    - University of Oklahoma Health Sciences Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 405-271-8777
      
      E-mail: ou-clinical-trials@ouhsc.edu
    - Ledende efterforsker:
      
      Hassan Hatoum
  - Oklahoma City, Oklahoma, Forenede Stater, 73109
    - Suspenderet
    - Integris Southwest Medical Center
  - Oklahoma City, Oklahoma, Forenede Stater, 73142
    - Suspenderet
    - Integris Cancer Institute of Oklahoma
  - Tulsa, Oklahoma, Forenede Stater, 74146
    - Aktiv, ikke rekrutterende
    - Oklahoma Cancer Specialists and Research Institute-Tulsa
- Oregon
  - Newberg, Oregon, Forenede Stater, 97132
    - Rekruttering
    - Providence Newberg Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 503-215-2614
      
      E-mail: CanRsrchStudies@providence.org
    - Ledende efterforsker:
      
      Charles W. Drescher
  - Ontario, Oregon, Forenede Stater, 97914
    - Rekruttering
    - Saint Alphonsus Cancer Care Center-Ontario
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 406-969-6060
      
      E-mail: mccinfo@mtcancer.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Oregon City, Oregon, Forenede Stater, 97045
    - Rekruttering
    - Providence Willamette Falls Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 503-215-2614
      
      E-mail: CanRsrchStudies@providence.org
    - Ledende efterforsker:
      
      Charles W. Drescher
  - Portland, Oregon, Forenede Stater, 97239
    - Rekruttering
    - Oregon Health and Science University
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 503-494-1080
      
      E-mail: trials@ohsu.edu
    - Ledende efterforsker:
      
      Emerson Y. Chen
  - Portland, Oregon, Forenede Stater, 97213
    - Rekruttering
    - Providence Portland Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 503-215-2614
      
      E-mail: CanRsrchStudies@providence.org
    - Ledende efterforsker:
      
      Charles W. Drescher
  - Portland, Oregon, Forenede Stater, 97225
    - Rekruttering
    - Providence Saint Vincent Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 503-215-2614
      
      E-mail: CanRsrchStudies@providence.org
    - Ledende efterforsker:
      
      Charles W. Drescher
- Pennsylvania
  - Allentown, Pennsylvania, Forenede Stater, 18103
    - Rekruttering
    - Lehigh Valley Hospital-Cedar Crest
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 610-402-9543
      
      E-mail: Morgan_M.Horton@lvhn.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Beaver, Pennsylvania, Forenede Stater, 15009
    - Rekruttering
    - UPMC-Heritage Valley Health System Beaver
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 412-389-5208
      
      E-mail: haneydl@upmc.edu
    - Ledende efterforsker:
      
      Anwaar Saeed
  - Bethlehem, Pennsylvania, Forenede Stater, 18017
    - Rekruttering
    - Lehigh Valley Hospital - Muhlenberg
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 610-402-9543
      
      E-mail: Morgan_M.Horton@lvhn.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Danville, Pennsylvania, Forenede Stater, 17822
    - Rekruttering
    - Geisinger Medical Center
    - Ledende efterforsker:
      
      Mina Makary
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 570-271-5251
      
      E-mail: cancerresearch@geisinger.edu
  - Dickson City, Pennsylvania, Forenede Stater, 18519
    - Rekruttering
    - Geisinger Cancer Center Dickson City
    - Ledende efterforsker:
      
      Mina Makary
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-204-6081
      
      E-mail: cancerresearch@geisinger.edu
  - East Stroudsburg, Pennsylvania, Forenede Stater, 18301
    - Rekruttering
    - Pocono Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 610-402-9543
      
      E-mail: Morgan_M.Horton@lvhn.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Erie, Pennsylvania, Forenede Stater, 16505
    - Rekruttering
    - UPMC Hillman Cancer Center Erie
    - Ledende efterforsker:
      
      Anwaar Saeed
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 412-864-7716
      
      E-mail: ClinicalResearchServices@upmc.edu
  - Greensburg, Pennsylvania, Forenede Stater, 15601
    - Rekruttering
    - UPMC Cancer Centers - Arnold Palmer Pavilion
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 724-838-1900
    - Ledende efterforsker:
      
      Anwaar Saeed
  - Harrisburg, Pennsylvania, Forenede Stater, 17109
    - Rekruttering
    - UPMC Pinnacle Cancer Center/Community Osteopathic Campus
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 717-724-6765
      
      E-mail: klitchfield@PINNACLEHEALTH.org
    - Ledende efterforsker:
      
      Anwaar Saeed
  - Hazleton, Pennsylvania, Forenede Stater, 18201
    - Rekruttering
    - Lehigh Valley Hospital-Hazleton
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 610-402-9543
      
      E-mail: Morgan_M.Horton@lvhn.org
    - Ledende efterforsker:
      
      Tareq Al baghdadi
  - Johnstown, Pennsylvania, Forenede Stater, 15901
    - Rekruttering
    - UPMC-Johnstown/John P. Murtha Regional Cancer Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 814-534-4724
    - Ledende efterforsker:
      
      Anwaar Saeed
  - Lancaster, Pennsylvania, Forenede Stater, 17601
    - Aktiv, ikke rekrutterende
    - Lancaster General Ann B Barshinger Cancer Institute
  - Lewisburg, Pennsylvania, Forenede Stater, 17837
    - Rekruttering
    - Geisinger Medical Oncology-Lewisburg
    - Ledende efterforsker:
      
      Mina Makary
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 570-523-9200
      
      E-mail: cancerresearch@geisinger.edu
  - Mechanicsburg, Pennsylvania, Forenede Stater, 17050
    - Rekruttering
    - UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 412-389-5208
      
      E-mail: haneydl@upmc.edu
    - Ledende efterforsker:
      
      Anwaar Saeed
  - Monroeville, Pennsylvania, Forenede Stater, 15146
    - Rekruttering
    - UPMC Hillman Cancer Center - Monroeville
    - Ledende efterforsker:
      
      Anwaar Saeed
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 412-864-7716
      
      E-mail: ClinicalResearchServices@upmc.edu
  - N. Huntingdon, Pennsylvania, Forenede Stater, 15642
    - Rekruttering
    - Arnold Palmer Cancer Center Medical Oncology Norwin
    - Ledende efterforsker:
      
      Anwaar Saeed
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 412-864-7716
      
      E-mail: ClinicalResearchServices@upmc.edu
  - New Castle, Pennsylvania, Forenede Stater, 16105
    - Rekruttering
    - UPMC Hillman Cancer Center - New Castle
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 412-389-5208
      
      E-mail: haneydl@upmc.edu
    - Ledende efterforsker:
      
      Anwaar Saeed
  - Philadelphia, Pennsylvania, Forenede Stater, 19107
    - Rekruttering
    - Thomas Jefferson University Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 215-600-9151
      
      E-mail: ONCTrialNow@jefferson.edu
    - Ledende efterforsker:
      
      Daniel Lin
  - Philadelphia, Pennsylvania, Forenede Stater, 19114
    - Rekruttering
    - Jefferson Torresdale Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 215-600-9151
      
      E-mail: ONCTrialNow@jefferson.edu
    - Ledende efterforsker:
      
      Daniel Lin
  - Pittsburgh, Pennsylvania, Forenede Stater, 15215
    - Rekruttering
    - UPMC-Saint Margaret
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 412-784-4900
    - Ledende efterforsker:
      
      Anwaar Saeed
  - Pittsburgh, Pennsylvania, Forenede Stater, 15237
    - Rekruttering
    - UPMC-Passavant Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 412-367-6454
    - Ledende efterforsker:
      
      Anwaar Saeed
  - Pittsburgh, Pennsylvania, Forenede Stater, 15243
    - Rekruttering
    - UPMC-Saint Clair Hospital Cancer Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 412-502-3920
    - Ledende efterforsker:
      
      Anwaar Saeed
  - Pittsburgh, Pennsylvania, Forenede Stater, 15232
    - Rekruttering
    - UPMC Hillman Cancer Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 412-647-8073
    - Ledende efterforsker:
      
      Anwaar Saeed
  - Scranton, Pennsylvania, Forenede Stater, 18510
    - Rekruttering
    - Community Medical Center
    - Ledende efterforsker:
      
      Mina Makary
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 570-703-4768
      
      E-mail: cancerresearch@geisinger.edu
  - Seneca, Pennsylvania, Forenede Stater, 16346
    - Rekruttering
    - UPMC Cancer Center at UPMC Northwest
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 814-676-7900
    - Ledende efterforsker:
      
      Anwaar Saeed
  - Uniontown, Pennsylvania, Forenede Stater, 15401
    - Rekruttering
    - UPMC Cancer Center-Uniontown
    - Kontakt:
      
      Site Public Contact
      
      E-mail: protocols@swog.org
    - Ledende efterforsker:
      
      Anwaar Saeed
  - Wilkes-Barre, Pennsylvania, Forenede Stater, 18711
    - Rekruttering
    - Geisinger Wyoming Valley/Henry Cancer Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 570-271-5251
      
      E-mail: HemonCCTrials@geisinger.edu
    - Ledende efterforsker:
      
      Mina Makary
  - Willow Grove, Pennsylvania, Forenede Stater, 19090
    - Rekruttering
    - Asplundh Cancer Pavilion
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 215-600-9151
      
      E-mail: ONCTrialNow@jefferson.edu
    - Ledende efterforsker:
      
      Daniel Lin
- Rhode Island
  - Westerly, Rhode Island, Forenede Stater, 02891
    - Rekruttering
    - Smilow Cancer Hospital Care Center - Westerly
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 203-785-5702
      
      E-mail: canceranswers@yale.edu
    - Ledende efterforsker:
      
      Yifei Zhang
- South Carolina
  - Charleston, South Carolina, Forenede Stater, 29425
    - Rekruttering
    - Medical University of South Carolina
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 843-792-9321
      
      E-mail: hcc-clinical-trials@musc.edu
    - Ledende efterforsker:
      
      Toros Dincman
  - Charleston, South Carolina, Forenede Stater, 29401
    - Rekruttering
    - Ralph H Johnson VA Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 843-789-7020
      
      E-mail: ashley.salvo@va.gov
    - Ledende efterforsker:
      
      Oleksandra Lupak
- South Dakota
  - Rapid City, South Dakota, Forenede Stater, 57701
    - Rekruttering
    - Rapid City Regional Hospital
    - Ledende efterforsker:
      
      Abdel-Ghani Azzouqa
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 605-755-2370
      
      E-mail: research@monument.health
  - Sioux Falls, South Dakota, Forenede Stater, 57104
    - Rekruttering
    - Sanford Cancer Center Oncology Clinic
    - Ledende efterforsker:
      
      Daniel Almquist
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 605-312-3320
      
      E-mail: OncologyClinicTrialsSF@sanfordhealth.org
  - Sioux Falls, South Dakota, Forenede Stater, 57117-5134
    - Rekruttering
    - Sanford USD Medical Center - Sioux Falls
    - Ledende efterforsker:
      
      Daniel Almquist
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 605-312-3320
      
      E-mail: OncologyClinicalTrialsSF@SanfordHealth.org
- Tennessee
  - Knoxville, Tennessee, Forenede Stater, 37920
    - Rekruttering
    - University of Tennessee - Knoxville
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 865-544-9773
    - Ledende efterforsker:
      
      Saikrishna Gadde
  - Nashville, Tennessee, Forenede Stater, 37232
    - Suspenderet
    - Vanderbilt University/Ingram Cancer Center
- Texas
  - Houston, Texas, Forenede Stater, 77030
    - Rekruttering
    - Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 713-798-1354
      
      E-mail: burton@bcm.edu
    - Ledende efterforsker:
      
      Karen Riggins
  - Houston, Texas, Forenede Stater, 77030
    - Rekruttering
    - Ben Taub General Hospital
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 713-873-2000
    - Ledende efterforsker:
      
      Karen Riggins
- Utah
  - Farmington, Utah, Forenede Stater, 84025
    - Rekruttering
    - Farmington Health Center
    - Ledende efterforsker:
      
      Christopher D. Nevala-Plagemann
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 888-424-2100
      
      E-mail: cancerinfo@hci.utah.edu
  - Salt Lake City, Utah, Forenede Stater, 84106
    - Rekruttering
    - University of Utah Sugarhouse Health Center
    - Ledende efterforsker:
      
      Christopher D. Nevala-Plagemann
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 888-424-2100
      
      E-mail: cancerinfo@hci.utah.edu
  - Salt Lake City, Utah, Forenede Stater, 84112
    - Rekruttering
    - Huntsman Cancer Institute/University of Utah
    - Ledende efterforsker:
      
      Christopher D. Nevala-Plagemann
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 888-424-2100
      
      E-mail: cancerinfo@hci.utah.edu
- Vermont
  - Berlin Corners, Vermont, Forenede Stater, 05602
    - Aktiv, ikke rekrutterende
    - Central Vermont Medical Center/National Life Cancer Treatment
  - Burlington, Vermont, Forenede Stater, 05401
    - Aktiv, ikke rekrutterende
    - University of Vermont Medical Center
  - Burlington, Vermont, Forenede Stater, 05405
    - Aktiv, ikke rekrutterende
    - University of Vermont and State Agricultural College
- Virginia
  - Richmond, Virginia, Forenede Stater, 23235
    - Rekruttering
    - VCU Massey Cancer Center at Stony Point
    - Ledende efterforsker:
      
      Jennifer L. Myers
    - Kontakt:
      
      Site Public Contact
      
      E-mail: ctoclinops@vcu.edu
  - Richmond, Virginia, Forenede Stater, 23298
    - Rekruttering
    - VCU Massey Comprehensive Cancer Center
    - Ledende efterforsker:
      
      Jennifer L. Myers
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 804-628-6430
      
      E-mail: CTOclinops@vcu.edu
- Wisconsin
  - Antigo, Wisconsin, Forenede Stater, 54409
    - Rekruttering
    - Aspirus Cancer Care-Antigo-Volm Cancer Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 715-623-9869
      
      E-mail: Juli.Alford@aspirus.org
    - Ledende efterforsker:
      
      Andrew J. Huang
  - Ashland, Wisconsin, Forenede Stater, 54806
    - Rekruttering
    - Duluth Clinic Ashland
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 218-786-3308
      
      E-mail: CancerTrials@EssentiaHealth.org
    - Ledende efterforsker:
      
      Bret E. Friday
  - Burlington, Wisconsin, Forenede Stater, 53105
    - Rekruttering
    - Aurora Cancer Care-Southern Lakes VLCC
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - Cudahy, Wisconsin, Forenede Stater, 53110
    - Rekruttering
    - Aurora Saint Luke's South Shore
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - Eau Claire, Wisconsin, Forenede Stater, 54701
    - Rekruttering
    - Marshfield Medical Center-EC Cancer Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-782-8581
      
      E-mail: oncology.clinical.trials@marshfieldresearch.org
    - Ledende efterforsker:
      
      Seth O. Fagbemi
  - Germantown, Wisconsin, Forenede Stater, 53022
    - Rekruttering
    - Aurora Health Care Germantown Health Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - Grafton, Wisconsin, Forenede Stater, 53024
    - Rekruttering
    - Aurora Cancer Care-Grafton
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - Green Bay, Wisconsin, Forenede Stater, 54311
    - Rekruttering
    - Aurora BayCare Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - Green Bay, Wisconsin, Forenede Stater, 54301
    - Rekruttering
    - Saint Vincent Hospital Cancer Center Green Bay
    - Ledende efterforsker:
      
      Matthew L. Ryan
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 920-433-8889
      
      E-mail: WI_research_admin@hshs.org
  - Green Bay, Wisconsin, Forenede Stater, 54303
    - Rekruttering
    - Saint Vincent Hospital Cancer Center at Saint Mary's
    - Ledende efterforsker:
      
      Matthew L. Ryan
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 920-433-8889
      
      E-mail: wi_research_admin@hshs.org
  - Kenosha, Wisconsin, Forenede Stater, 53142
    - Rekruttering
    - Aurora Cancer Care-Kenosha South
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - Madison, Wisconsin, Forenede Stater, 53705
    - Rekruttering
    - William S Middleton VA Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 17007 608-256-1901
    - Ledende efterforsker:
      
      Sam J. Lubner
  - Madison, Wisconsin, Forenede Stater, 53792
    - Rekruttering
    - University of Wisconsin Carbone Cancer Center - University Hospital
    - Ledende efterforsker:
      
      Nataliya V. Uboha
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-622-8922
      
      E-mail: clinicaltrials@cancer.wisc.edu
  - Madison, Wisconsin, Forenede Stater, 53718
    - Rekruttering
    - University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
    - Ledende efterforsker:
      
      Nataliya V. Uboha
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-622-8922
      
      E-mail: clinicaltrials@cancer.wisc.edu
  - Marinette, Wisconsin, Forenede Stater, 54143
    - Rekruttering
    - Aurora Bay Area Medical Group-Marinette
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - Marshfield, Wisconsin, Forenede Stater, 54449
    - Rekruttering
    - Marshfield Medical Center-Marshfield
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-782-8581
      
      E-mail: oncology.clinical.trials@marshfieldresearch.org
    - Ledende efterforsker:
      
      Seth O. Fagbemi
  - Medford, Wisconsin, Forenede Stater, 54451
    - Rekruttering
    - Aspirus Medford Hospital
    - Ledende efterforsker:
      
      Andrew J. Huang
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 715-847-2353
      
      E-mail: Beth.Knetter@aspirus.org
  - Milwaukee, Wisconsin, Forenede Stater, 53209
    - Rekruttering
    - Aurora Cancer Care-Milwaukee
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - Milwaukee, Wisconsin, Forenede Stater, 53215
    - Rekruttering
    - Aurora Saint Luke's Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - Milwaukee, Wisconsin, Forenede Stater, 53233
    - Rekruttering
    - Aurora Sinai Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - Minocqua, Wisconsin, Forenede Stater, 54548
    - Rekruttering
    - Marshfield Medical Center - Minocqua
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-782-8581
      
      E-mail: oncology.clinical.trials@marshfieldresearch.org
    - Ledende efterforsker:
      
      Seth O. Fagbemi
  - Mukwonago, Wisconsin, Forenede Stater, 53149
    - Rekruttering
    - ProHealth D N Greenwald Center
    - Kontakt:
      
      Site Public Contact
      
      E-mail: research.institute@phci.org
    - Ledende efterforsker:
      
      Timothy R. Wassenaar
  - Oconomowoc, Wisconsin, Forenede Stater, 53066
    - Rekruttering
    - ProHealth Oconomowoc Memorial Hospital
    - Ledende efterforsker:
      
      Timothy R. Wassenaar
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 262-928-7878
  - Oconto Falls, Wisconsin, Forenede Stater, 54154
    - Rekruttering
    - Saint Vincent Hospital Cancer Center at Oconto Falls
    - Ledende efterforsker:
      
      Matthew L. Ryan
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 920-433-8889
      
      E-mail: WI_research_admin@hshs.org
  - Oshkosh, Wisconsin, Forenede Stater, 54904
    - Rekruttering
    - Vince Lombardi Cancer Clinic - Oshkosh
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - Racine, Wisconsin, Forenede Stater, 53406
    - Rekruttering
    - Aurora Cancer Care-Racine
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - Rhinelander, Wisconsin, Forenede Stater, 54501
    - Rekruttering
    - Aspirus Cancer Care-Rhinelander-James Beck Cancer Center
    - Ledende efterforsker:
      
      Andrew J. Huang
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 715-847-2353
      
      E-mail: Beth.Knetter@aspirus.org
  - Rice Lake, Wisconsin, Forenede Stater, 54868
    - Rekruttering
    - Marshfield Medical Center-Rice Lake
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-782-8581
      
      E-mail: oncology.clinical.trials@marshfieldresearch.org
    - Ledende efterforsker:
      
      Seth O. Fagbemi
  - Sheboygan, Wisconsin, Forenede Stater, 53081
    - Rekruttering
    - Vince Lombardi Cancer Clinic-Sheboygan
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - Sheboygan, Wisconsin, Forenede Stater, 53081
    - Rekruttering
    - Saint Vincent Hospital Cancer Center at Sheboygan
    - Ledende efterforsker:
      
      Matthew L. Ryan
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 920-433-8889
      
      E-mail: wi_research_admin@hshs.org
  - Sheboygan, Wisconsin, Forenede Stater, 53081
    - Rekruttering
    - Sheboygan Physicians Group
    - Ledende efterforsker:
      
      Matthew L. Ryan
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 920-433-8889
      
      E-mail: wi_research_admin@hshs.org
  - Stevens Point, Wisconsin, Forenede Stater, 54482
    - Rekruttering
    - Marshfield Medical Center-River Region at Stevens Point
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-782-8581
      
      E-mail: oncology.clinical.trials@marshfieldresearch.org
    - Ledende efterforsker:
      
      Seth O. Fagbemi
  - Stevens Point, Wisconsin, Forenede Stater, 54481
    - Rekruttering
    - Aspirus Cancer Care - Stevens Point
    - Ledende efterforsker:
      
      Andrew J. Huang
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 715-847-2353
      
      E-mail: Beth.Knetter@aspirus.org
  - Sturgeon Bay, Wisconsin, Forenede Stater, 54235-1495
    - Rekruttering
    - Saint Vincent Hospital Cancer Center at Sturgeon Bay
    - Ledende efterforsker:
      
      Matthew L. Ryan
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 920-433-8889
      
      E-mail: wi_research_admin@hshs.org
  - Summit, Wisconsin, Forenede Stater, 53066
    - Rekruttering
    - Aurora Medical Center in Summit
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - Two Rivers, Wisconsin, Forenede Stater, 54241
    - Rekruttering
    - Vince Lombardi Cancer Clinic-Two Rivers
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - Waukesha, Wisconsin, Forenede Stater, 53188
    - Rekruttering
    - ProHealth Waukesha Memorial Hospital
    - Ledende efterforsker:
      
      Timothy R. Wassenaar
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 262-928-7632
  - Waukesha, Wisconsin, Forenede Stater, 53188
    - Rekruttering
    - UW Cancer Center at ProHealth Care
    - Ledende efterforsker:
      
      Timothy R. Wassenaar
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 262-928-5539
      
      E-mail: Chanda.miller@phci.org
  - Wausau, Wisconsin, Forenede Stater, 54401
    - Rekruttering
    - Aspirus Cancer Care-Wausau
    - Ledende efterforsker:
      
      Andrew J. Huang
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 877-405-6866
  - Wauwatosa, Wisconsin, Forenede Stater, 53226
    - Rekruttering
    - Aurora Cancer Care-Milwaukee West
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - West Allis, Wisconsin, Forenede Stater, 53227
    - Rekruttering
    - Aurora West Allis Medical Center
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 414-302-2304
      
      E-mail: ncorp@aurora.org
    - Ledende efterforsker:
      
      Edward S. James
  - Weston, Wisconsin, Forenede Stater, 54476
    - Rekruttering
    - Marshfield Medical Center - Weston
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 800-782-8581
      
      E-mail: oncology.clinical.trials@marshfieldresearch.org
    - Ledende efterforsker:
      
      Seth O. Fagbemi
  - Wisconsin Rapids, Wisconsin, Forenede Stater, 54494
    - Rekruttering
    - Aspirus Cancer Care - Wisconsin Rapids
    - Ledende efterforsker:
      
      Andrew J. Huang
    - Kontakt:
      
      Site Public Contact
      
      Telefonnummer: 715-422-7718

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

18 år og ældre (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Køn, der er berettiget til at studere

Alle

Beskrivelse

Inclusion Criteria:

Participants must have advanced or locally unresectable gastric, gastroesophageal junction or esophageal adenocarcinoma
Participants must have PD-L1 CPS (Combined Positive Score) ≥ 1. This test would have been performed as part of standard of care (SOC) pathology testing, using tissue obtained within two years prior to registration and collected prior to or after a frontline regimen
Participants must have a histologically confirmed diagnosis of microsatellite stable (MSS) and HER2 negative gastric, gastroesophageal junction, or esophageal adenocarcinoma
Participants must have documented unresectable and/or metastatic disease on CT or MRI imaging completed prior to registration. Imaging must have been completed within 28 days prior to registration for participants with measurable disease. CT scans or MRIs used to assess non-measurable disease must have been completed within 42 days prior to registration. All disease must be assessed and documented on the Baseline Tumor Assessment Form
Participants with treated brain metastases must have no evidence of progression on the follow-up brain imaging after central nervous system (CNS)-directed therapy. All treatment for brain metastases must have been completed at least 28 days prior to registration
Participants must have disease progression or intolerance to frontline standard of care (SOC) chemotherapy plus either nivolumab, pembrolizumab or any other PD-1 or PD-L1 inhibitor. Peri-operative chemotherapy plus nivolumab, pembrolizumab or any other PD-1 or PD-L1 inhibitor will count as one line if disease progression occurs while on the therapy or within 6 months of completing the chemotherapy plus nivolumab or pembrolizumab or other PD-1/PD-L1 inhibitor cycle
Participants must not have received more than one prior line of systemic therapy defined as chemotherapy plus either nivolumab, pembrolizumab, or any other PD-1 or PD-L1 inhibitor, in the stage IV or unresectable setting. Peri-operative or adjuvant nivoluamb or other PD-1/PD-L1 inhibitors would count as one prior line of systemic therapy if patients progressed while on nivolumab (or other PD-1/PD-L1 inhibitors) or within 6 months of stopping it
- Note: Radiation or any other regional therapy options done to address local residual disease or metastatic disease would not count as a line of therapy. Maintenance therapy with a different form of fluoropyrimidine (i.e. switching from capecitabine to fluorouracil [5FU]) would not count as another line of therapy
Participants must not have a condition requiring systemic treatment with either corticosteroids (> 10 mg daily prednisone equivalents) or other immunosuppressive medications within 14 days of registration. Inhaled or topical steroids and adrenal replacement doses < 10 mg daily prednisone equivalents are permitted in the absence of active autoimmune disease. Participants are permitted to use topical, ocular, intra-articular, intranasal, and inhalational corticosteroids (with minimal systemic absorption). Physiologic replacement doses of systemic corticosteroids are permitted, even if < 10 mg/day prednisone equivalents. A brief course of corticosteroids for prophylaxis (e.g., contrast dye allergy) or for treatment of non-autoimmune conditions (e.g., delayed-type hypersensitivity reaction caused by contact allergen) is permitted, as long as there has been a washout period for corticosteroids of ≥ 7 days prior to registration
Participants must not have prior significant immunotherapy related adverse events requiring permanent discontinuation of the immunotherapy agent including events like pneumonitis, myocarditis, renal failure, Guillain barre syndrome, or myasthenia gravis. Participants with endocrinopathy events leading or not to replacement steroids, thyroid hormone, insulin, or cortisol are eligible
Participants must not have received a live attenuated vaccination within 28 days prior to registration
Participants must not have had a major surgery within 28 days or subcutaneous venous access device placement within 7 days prior registration
Participants must have fully recovered from the effects of prior surgery in the opinion of the treating investigator. Any participants with postoperative bleeding complications or wound complications from a surgical procedure performed in the last eight weeks should be excluded
Participants must not have plans to undergo elective or planned major surgery during the clinical trial
Participants must not have active bleeding or prior history of gastrointestinal (GI) perforation, fistula or significant GI bleeding (requiring transfusion, endoscopic or surgical intervention) within 84 days prior to registration
Participants must not be planning to receive any concurrent chemotherapy, immunotherapy, investigational agents, biologic or hormonal therapy for cancer treatment while receiving treatment on this study
Participants must not have a history of a grade 3 or 4 allergic reaction attributed to humanized or human monoclonal antibody therapy
Participants must not have a history of grade 3 or 4 immunotherapy related toxicities with the exception of hormonal abnormalities like thyroiditis or thyroid derangements
Participants must be ≥ 18 years old
Participants must have Zubrod Performance Status of 0-2
Participants must have a complete medical history and physical exam within 28 days prior to registration
Leukocytes ≥ 2 x 10^3/uL (within 28 days prior to registration)
Absolute neutrophil count ≥ 1.2 x 10^3/uL (within 28 days prior to registration)
Hemoglobin ≥ 9.0 g/dL (within 28 days prior to registration)
Platelets ≥ 100 x 10^3/uL (within 28 days prior to registration)
Total bilirubin ≤ 1.5 x institutional upper limit of normal (ULN) (within 28 days prior to registration) unless history of Gilbert's disease. Participants with history of Gilbert's disease must have total bilirubin ≤ 5 x institutional ULN
Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) ≤ 3 × institutional ULN (within 28 days prior to registration) (unless liver metastases are present, in which case they must be ≤ 5 x ULN)
Participants must have a calculated creatinine clearance ≥ 40 mL/min using the following Cockcroft-Gault Formula. This specimen must have been drawn and processed within 28 days prior to registration
Participants' urinary protein must be ≤ 1+ on dipstick or routine urinalysis (UA) within 28 days of registration. Random analysis of urine protein with a normal value is sufficient. If urine dipstick or routine analysis indicated proteinuria ≥ 2+, then a 24-hour urine is to be collected and demonstrate < 1000 mg of protein in 24 hours to allow participation in the study
Participants must have adequate cardiac function. Participants with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, must have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, participants must be class 2 or better
Participants must have recovered to baseline or < grade 2 CTCAE version (v) 5.0 from toxicities related to any prior treatments, unless AE(s) are clinically stable on supportive therapy
Participants must not have experienced arterial thromboembolic events, including but not limited to myocardial infarction, transient ischemic attack, cerebrovascular accident, or unstable angina, within 6 months prior to registration
Participants must not have uncontrolled blood pressure within 28 days prior to registration as determined by the treating investigator
Participants with known human immunodeficiency virus (HIV)-infection must be on effective anti-retroviral therapy at registration and have undetectable viral load on the most recent test results obtained within 6 months prior to registration
Participants with evidence of chronic hepatitis B virus (HBV) infection must have undetectable HBV viral load while on suppressive therapy on the most recent test results obtained within 6 months prior to registration, if indicated
Participants with a history of hepatitis C virus (HCV) infection must have been treated and cured. Participants currently being treated for HCV infection must have undetectable HCV viral load on the most recent test results obtained within 6 months prior to registration, if indicated
Participants must not have a prior or concurrent malignancy whose natural history or treatment (in the opinion of the treating physician) has the potential to interfere with the safety or efficacy assessment of the investigational regimen
Participants must not be pregnant or nursing (nursing includes breast milk fed to an infant by any means, including from the breast, milk expressed by hand, or pumped). Individuals who are of reproductive potential must have agreed to use an effective contraceptive method with details provided as a part of the consent process. A person who has had menses at any time in the preceding 12 consecutive months or who has semen likely to contain sperm is considered to be of "reproductive potential." In addition to routine contraceptive methods, "effective contraception" also includes refraining from sexual activity that might result in pregnancy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) including hysterectomy, bilateral oophorectomy, bilateral tubal ligation/occlusion, and vasectomy with testing showing no sperm in the semen
Participants must not have a history of inflammatory bowel disease, (including ulcerative colitis and Crohn's disease), symptomatic autoimmune disease (e.g., rheumatoid arthritis, systemic progressive sclerosis [scleroderma], systemic lupus erythematosus, autoimmune vasculitis [e.g., Wegener's Granulomatosis]); CNS or motor neuropathy considered of autoimmune origin (e.g., Guillain-Barre Syndrome and myasthenia gravis, multiple sclerosis). Note: Participants with Graves' disease will be allowed
Participants must not have a history of pneumonitis that has required oral or IV steroids within the last 12 months prior to registration
Participants must be offered the opportunity to participate in specimen banking. With participant consent, specimens must be collected and submitted via the Southwest Oncology Group (SWOG) Specimen Tracking System
Participants who can complete patient reported outcomes (FACT-Ga and PRO-CTCAE) questionnaires in English or Spanish must participate in the quality of life studies
Participants must be informed of the investigational nature of this study and must sign and give informed consent in accordance with institutional and federal guidelines. For participants with impaired decision-making capabilities, legally authorized representatives may sign and give informed consent on behalf of study participants in accordance with applicable federal, local, and Central Institutional Review Board (CIRB) regulations

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Primært formål: Behandling
Tildeling: Randomiseret
Interventionel model: Parallel tildeling
Maskning: Ingen (Åben etiket)

Antal våben

Våben og indgreb

Deltagergruppe / Arm	Intervention / Behandling
Eksperimentel: Arm 1 (nivolumab, ramucirumab, paclitaxel) Patients receive nivolumab IV over 30 minutes on day 1 of each cycle, ramucirumab IV over 30-60 minutes on days 1 and 15 of each cycle, and paclitaxel IV over 60 minutes on days 1, 8 and 15 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan and MRI throughout the study. Patients may also optionally undergo blood sample collection on study.	Medicin: Paclitaxel Given IV Andre navne: Taxol Anzatax Asotax Bristaxol Praxel Taxol Konzentrat Procedure: Magnetic Resonance Imaging Undergo MRI Andre navne: MR Magnetisk resonans Magnetisk resonansbilledscanning Medicinsk billeddannelse, magnetisk resonans / kernemagnetisk resonans HR MR billeddannelse MR-scanning NMR billeddannelse NMRI Kernemagnetisk resonansbilleddannelse Magnetisk resonansbilleddannelse (MRI) sMRI Magnetisk resonansbilleddannelse (procedure) MRI'er Strukturel MR Andet: Questionnaire Administration Ancillary studies Biologisk: Nivolumab Given IV Andre navne: BMS-936558 MDX-1106 NIVO ONO-4538 Opdivo CMAB819 Nivolumab Biosimilar CMAB819 MDX 1106 MDX1106 BMS 936558 ABP 206 Nivolumab Biosimilar ABP 206 BCD-263 Nivolumab Biosimilar BCD-263 BMS936558 ONO 4538 ONO4538 Procedure: Computed Tomography Undergo CT scan Andre navne: CT KAT CAT-scanning Beregnet aksial tomografi Computerstyret aksial tomografi Computerstyret tomografi CT-scanning tomografi Computerstyret aksial tomografi (procedure) Computerstyret tomografi (CT) scanning Diagnostisk CAT -scanning Diagnostic CAT Scan Service Type Biologisk: Ramucirumab Given IV Andre navne: LY3009806 LY 3009806 IMC-1121B Cyramza Anti-VEGFR-2 fuldt humant monoklonalt antistof IMC-1121B Monoklonalt antistof HGS-ETR2 IMC 1121B IMC1121B LY-3009806 Procedure: Biospecimen Collection Undergo optional blood sample collection Andre navne: Biologisk prøvesamling Bioprøve indsamlet Prøvesamling Prøvekollektion
Aktiv komparator: Arm 2 (ramucirumab, paclitaxel) Patients receive ramucirumab IV over 30-60 minutes on days 1 and 15 of each cycle and paclitaxel IV over 60 minutes on days 1, 8 and 15 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan and MRI throughout the study. Patients may also optionally undergo blood sample collection on study.	Medicin: Paclitaxel Given IV Andre navne: Taxol Anzatax Asotax Bristaxol Praxel Taxol Konzentrat Procedure: Magnetic Resonance Imaging Undergo MRI Andre navne: MR Magnetisk resonans Magnetisk resonansbilledscanning Medicinsk billeddannelse, magnetisk resonans / kernemagnetisk resonans HR MR billeddannelse MR-scanning NMR billeddannelse NMRI Kernemagnetisk resonansbilleddannelse Magnetisk resonansbilleddannelse (MRI) sMRI Magnetisk resonansbilleddannelse (procedure) MRI'er Strukturel MR Andet: Questionnaire Administration Ancillary studies Procedure: Computed Tomography Undergo CT scan Andre navne: CT KAT CAT-scanning Beregnet aksial tomografi Computerstyret aksial tomografi Computerstyret tomografi CT-scanning tomografi Computerstyret aksial tomografi (procedure) Computerstyret tomografi (CT) scanning Diagnostisk CAT -scanning Diagnostic CAT Scan Service Type Biologisk: Ramucirumab Given IV Andre navne: LY3009806 LY 3009806 IMC-1121B Cyramza Anti-VEGFR-2 fuldt humant monoklonalt antistof IMC-1121B Monoklonalt antistof HGS-ETR2 IMC 1121B IMC1121B LY-3009806 Procedure: Biospecimen Collection Undergo optional blood sample collection Andre navne: Biologisk prøvesamling Bioprøve indsamlet Prøvesamling Prøvekollektion

Deltagergruppe / Arm

Intervention / Behandling

Eksperimentel: Arm 1 (nivolumab, ramucirumab, paclitaxel)

Patients receive nivolumab IV over 30 minutes on day 1 of each cycle, ramucirumab IV over 30-60 minutes on days 1 and 15 of each cycle, and paclitaxel IV over 60 minutes on days 1, 8 and 15 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan and MRI throughout the study. Patients may also optionally undergo blood sample collection on study.

Medicin: Paclitaxel

Given IV

Andre navne:

Taxol
Anzatax
Asotax
Bristaxol
Praxel
Taxol Konzentrat

Procedure: Magnetic Resonance Imaging

Undergo MRI

Andre navne:

MR
Magnetisk resonans
Magnetisk resonansbilledscanning
Medicinsk billeddannelse, magnetisk resonans / kernemagnetisk resonans
HR
MR billeddannelse
MR-scanning
NMR billeddannelse
NMRI
Kernemagnetisk resonansbilleddannelse
Magnetisk resonansbilleddannelse (MRI)
sMRI
Magnetisk resonansbilleddannelse (procedure)
MRI'er
Strukturel MR

Andet: Questionnaire Administration

Ancillary studies

Biologisk: Nivolumab

Given IV

Andre navne:

BMS-936558
MDX-1106
NIVO
ONO-4538
Opdivo
CMAB819
Nivolumab Biosimilar CMAB819
MDX 1106
MDX1106
BMS 936558
ABP 206
Nivolumab Biosimilar ABP 206
BCD-263
Nivolumab Biosimilar BCD-263
BMS936558
ONO 4538
ONO4538

Procedure: Computed Tomography

Undergo CT scan

Andre navne:

CT
KAT
CAT-scanning
Beregnet aksial tomografi
Computerstyret aksial tomografi
Computerstyret tomografi
CT-scanning
tomografi
Computerstyret aksial tomografi (procedure)
Computerstyret tomografi (CT) scanning
Diagnostisk CAT -scanning
Diagnostic CAT Scan Service Type

Biologisk: Ramucirumab

Given IV

Andre navne:

LY3009806
LY 3009806
IMC-1121B
Cyramza
Anti-VEGFR-2 fuldt humant monoklonalt antistof IMC-1121B
Monoklonalt antistof HGS-ETR2
IMC 1121B
IMC1121B
LY-3009806

Procedure: Biospecimen Collection

Undergo optional blood sample collection

Andre navne:

Biologisk prøvesamling
Bioprøve indsamlet
Prøvesamling
Prøvekollektion

Aktiv komparator: Arm 2 (ramucirumab, paclitaxel)

Patients receive ramucirumab IV over 30-60 minutes on days 1 and 15 of each cycle and paclitaxel IV over 60 minutes on days 1, 8 and 15 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients undergo CT scan and MRI throughout the study. Patients may also optionally undergo blood sample collection on study.

Medicin: Paclitaxel

Given IV

Andre navne:

Taxol
Anzatax
Asotax
Bristaxol
Praxel
Taxol Konzentrat

Procedure: Magnetic Resonance Imaging

Undergo MRI

Andre navne:

MR
Magnetisk resonans
Magnetisk resonansbilledscanning
Medicinsk billeddannelse, magnetisk resonans / kernemagnetisk resonans
HR
MR billeddannelse
MR-scanning
NMR billeddannelse
NMRI
Kernemagnetisk resonansbilleddannelse
Magnetisk resonansbilleddannelse (MRI)
sMRI
Magnetisk resonansbilleddannelse (procedure)
MRI'er
Strukturel MR

Andet: Questionnaire Administration

Ancillary studies

Procedure: Computed Tomography

Undergo CT scan

Andre navne:

CT
KAT
CAT-scanning
Beregnet aksial tomografi
Computerstyret aksial tomografi
Computerstyret tomografi
CT-scanning
tomografi
Computerstyret aksial tomografi (procedure)
Computerstyret tomografi (CT) scanning
Diagnostisk CAT -scanning
Diagnostic CAT Scan Service Type

Biologisk: Ramucirumab

Given IV

Andre navne:

LY3009806
LY 3009806
IMC-1121B
Cyramza
Anti-VEGFR-2 fuldt humant monoklonalt antistof IMC-1121B
Monoklonalt antistof HGS-ETR2
IMC 1121B
IMC1121B
LY-3009806

Procedure: Biospecimen Collection

Undergo optional blood sample collection

Andre navne:

Biologisk prøvesamling
Bioprøve indsamlet
Prøvesamling
Prøvekollektion

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Progression free survival (PFS) (Phase II) Tidsramme: From date of randomization to date of first documentation of progression or symptomatic deterioration or death due to any cause, assessed up to 3 years	The distribution of PFS will be estimated using the method of Kaplan-Meier and compared using a 1-sided stratified log-rank test.	From date of randomization to date of first documentation of progression or symptomatic deterioration or death due to any cause, assessed up to 3 years
Overall survival (OS) (Phase III) Tidsramme: From date of randomization to date of death due to any cause, assessed up to 3 years	The distribution of OS will be estimated using the method of Kaplan-Meier and compared using a 1-sided stratified log-rank test.	From date of randomization to date of death due to any cause, assessed up to 3 years

Sekundære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Forekomst af uønskede hændelser Tidsramme: Op til 3 år		Op til 3 år
Objective response rate (ORR) Tidsramme: Up to 3 years	Will be compared across arms in participants with measurable disease via Fisher's exact test.	Up to 3 years
Disease control rate (DCR) Tidsramme: Up to 3 years	DCR = ORR + stable disease per Response Evaluation Criteria in Solid Tumors 1.1. Will be compared across arms in participants with measurable disease via Fisher's exact test.	Up to 3 years

Andre resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Disease-free survival (DFS) Tidsramme: Up to 3 years	The hazard ratio of DFS and the corresponding 95% confidence intervals will be estimated for subgroups defined by sex, race, and ethnicity, respectively.	Up to 3 years

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

National Cancer Institute (NCI)

Efterforskere

Ledende efterforsker: Anwaar Saeed, SWOG Cancer Research Network

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Saeed A, Colby S, Oberstein PE, Duda DG, Park R, Agarwal R, Figueroa-Moseley C, Vaidya R, Unger JM, Guthrie KA, Rocha FG, Senthil M, Safyan RA, Wainberg ZA, Iqbal S, Chiorean EG, Philip PA. S2303: phase II/III trial of paclitaxel + ramucirumab +/- nivolumab in gastric and esophageal adenocarcinoma (PARAMUNE). Future Oncol. 2025 May;21(11):1325-1331. doi: 10.1080/14796694.2025.2485020. Epub 2025 Mar 28.

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

24. juni 2024

Primær færdiggørelse (Anslået)

31. oktober 2027

Studieafslutning (Anslået)

31. oktober 2027

Datoer for studieregistrering

Først indsendt

10. januar 2024

Først indsendt, der opfyldte QC-kriterier

10. januar 2024

Først opslået (Faktiske)

12. januar 2024

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

30. oktober 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

29. oktober 2026

Sidst verificeret

1. august 2026

Mere information

Begreber relateret til denne undersøgelse

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

NCI-2023-11064
U10CA180888 (U.S. NIH-bevilling/kontrakt)
NCI-2023-11064 (Registry Identifier: CTRP (Clinical Trial Reporting Program))
S2303 (Anden identifikator: CTEP)
S2303 (Anden identifikator: SWOG)

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

IPD-planbeskrivelse

"NCI is committed to sharing data in accordance with NIH policy. For more details on how clinical trial data is shared, access the link to the NIH data sharing policy page."

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

Studerer et amerikansk FDA-reguleret lægemiddelprodukt

Studerer et amerikansk FDA-reguleret enhedsprodukt

Ingen

produkt fremstillet i og eksporteret fra U.S.A.

Ingen

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Tilføjelse af Nivolumab til sædvanlig behandling for mennesker med avanceret mave- eller spiserørskræft, PARAMMUNE-forsøget

Randomized Phase II/III Trial of 2nd Line Nivolumab + Paclitaxel + Ramucirumab Versus Paclitaxel + Ramucirumab in Patients With PD-L1 CPS &gt;/= 1 Advanced Gastric and Esophageal Adenocarcinoma (PARAMUNE)

Studieoversigt

Status

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

Undersøgelsestype

Tilmelding (Anslået)

Fase

Kontakter og lokationer

Studiesteder

Deltagelseskriterier

Berettigelseskriterier

Aldre berettiget til at studere

Tager imod sunde frivillige

Køn, der er berettiget til at studere

Beskrivelse

Studieplan

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Antal våben

Våben og indgreb

Deltagergruppe / Arm

Intervention / Behandling

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Sekundære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Andre resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Samarbejdspartnere og efterforskere

Sponsor

Efterforskere

Publikationer og nyttige links

Generelle publikationer

Datoer for undersøgelser

Studer store datoer

Studiestart (Faktiske)

Primær færdiggørelse (Anslået)

Studieafslutning (Anslået)

Datoer for studieregistrering

Først indsendt

Først indsendt, der opfyldte QC-kriterier

Først opslået (Faktiske)

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

Sidst verificeret

Mere information

Begreber relateret til denne undersøgelse

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

IPD-planbeskrivelse

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

Studerer et amerikansk FDA-reguleret lægemiddelprodukt

Studerer et amerikansk FDA-reguleret enhedsprodukt

produkt fremstillet i og eksporteret fra U.S.A.

Randomized Phase II/III Trial of 2nd Line Nivolumab + Paclitaxel + Ramucirumab Versus Paclitaxel + Ramucirumab in Patients With PD-L1 CPS >/= 1 Advanced Gastric and Esophageal Adenocarcinoma (PARAMUNE)