Økende kolorektal- og brystkreftscreening hos kvinner (COBRA)
8. september 2017 oppdatert av: Victoria L. Champion, Indiana University
Denne studien sammenligner effekten (overholdelse og stadium) av fire intervensjoner for å fremme screening av kolorektal (CRC) og brystkreft (BC) blant kvinner i alderen 50 til 75 år. De er:
- vanlig omsorg;
- et TIWeb (skreddersydd intervensjonsnettsted)
- en CSC (kreftscreening call) og
- TIWeb + en CSC. Denne studien sammenligner også kostnadseffektiviteten til de 4 intervensjonene for å fremme CRC- og BC-screening blant kvinner i alderen 50 til 75 år.
Studieoversikt
Status
Fullført
Forhold
Intervensjon / Behandling
Detaljert beskrivelse
Denne studien tar for seg innovative tilnærminger for å øke etterlevelsen av screeningtester for tykktarm- og brystkreft - to kreftformer som har størst innvirkning på kvinnelig kreftdødelighet i USA. Kreftbyrden hos kvinner kan reduseres betydelig ved å øke deltakelsen i anbefalt screening for kolorektal kreft. kreft (CRC) og brystkreft (BC) hos alle kvalifiserte kvinner.
Denne forskningen tester intervensjon for samtidig å øke både CRC- og BC-screening ved å bruke atferdsendringsstrategier, og estimerer også effektiviteten og kostnadseffektiviteten til intervensjonene.
To grupper kvinner, gruppe A (følger retningslinjene for BC-screening, men IKKE CRC-screening-retningslinjene) og gruppe B (ikke-følger BC & CRC-retningslinjene) er randomisert til 1. Vanlig omsorg, 2. TIWeb, 3. CSC og 4. TIWeb +CSC.
Studietype
Intervensjonell
Registrering (Faktiske)
1196
Fase
- Ikke aktuelt
Deltakelseskriterier
Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.
Kvalifikasjonskriterier
Alder som er kvalifisert for studier
50 år til 75 år (VOKSEN, OLDER_ADULT)
Tar imot friske frivillige
Ja
Kjønn som er kvalifisert for studier
Hunn
Beskrivelse
Inklusjonskriterier:
- en pasient av noen av de deltakende legene
- ikke ha tatt en fekal okkult blodprøve (fobt) de siste 12 månedene
- ikke har hatt en avføringsimmunokjemisk test (tilpasning) de siste 15 månedene
- ikke hatt sigmoidoskopi for mer enn 5 år siden
- ikke ha tatt koloskopi for mer enn 10 år siden
- har høyhastighets internettilgang
Eksklusjonskriterier
- en personlig historie med tykktarmskreft
- en personlig historie med brystkreft
- en personlig historie med kolorektale polypper
- en personlig historie med inflammatorisk tarmsykdom
- har noen medisinske tilstander som vil forby en mammografi eller CRC-screening
- har allerede hatt CRC-screening
Studieplan
Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.
Hvordan er studiet utformet?
Designdetaljer
- Primært formål: FOREBYGGING
- Tildeling: TILFELDIG
- Intervensjonsmodell: FAKTORIAL
- Masking: INGEN
Våpen og intervensjoner
Deltakergruppe / Arm |
Intervensjon / Behandling |
|---|---|
|
PLACEBO_COMPARATOR: Vanlig omsorg (UC)
Den vanlige omsorgsgruppen fikk vanlig omsorg som varierer avhengig av praksisinnstillingen.
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Intervensjon: Den vanlige omsorgsgruppen fikk vanlig omsorg som varierer avhengig av praksisinnstillingen.
Andre navn:
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ACTIVE_COMPARATOR: TIWeb
TIWeb (Tailored Web Intervention)-programmet er interaktivt og skreddersydd til deltakerens individuelle tro og demografi.
Personer som mottar TIWeb vil bli gitt informasjon som gjør at de kan ringe og motta et FOBT-sett i posten eller planlegge en passende CRC-test og/eller mammografi.
|
Intervensjon: TIWeb-programmet er interaktivt og skreddersydd til deltakerens individuelle tro og demografi.
Personer som mottar TIWeb vil bli gitt informasjon som gjør at de kan ringe og motta et FOBT-sett i posten eller planlegge en passende CRC-test og/eller mammografi.
Andre navn:
|
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ACTIVE_COMPARATOR: Kreftscreeningsanrop (CSC)
CSC - en telefonveiledningssamtale hvor deltakeren får muligheten til å gjennomføre CRC-screening (FOBT eller en koloskopi) og/eller mammografiscreening. CSC inkluderte skreddersydd rådgivning samt muligheten til å planlegge BC- og CRC-screeningstester.
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Intervensjon: CSC - en telefonveiledningssamtale der deltakeren gis mulighet til å gjennomføre CRC-screening (FOBT eller en koloskopi) og/eller mammografiscreening. CSC inkluderte skreddersydd rådgivning samt muligheten til å planlegge BC- og CRC-screeningstester.
Andre navn:
|
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ACTIVE_COMPARATOR: TIWeb+CSC
TIWeb + CSC ((Tilored web intervetion+Cancer screening)-gruppen mottar en postet TIWeb, som etter fire uker følges av en CSC med samme mulighet til å motta FOBT-sett eller planlegge en koloskopi og/eller mammografi.
Sykepleierrådgiveren, som vet at deltakeren er en god kandidat for screeningtester, vil bli opplært til å planlegge CRC- eller BC-screeningavtaler eller til å sende FOBT-sett til enkeltpersoner i intervensjonsgruppene selv om de ikke har hatt et nylig klinikkbesøk.
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Intervensjon: TIWeb + CSC ((Tilored web intervetion+Cancer screening) gruppe mottar en TIWeb tilsendt per post, som etter fire uker følges av en CSC med samme mulighet til å motta FOBT-sett eller planlegge en koloskopi og/eller mammografi.
Sykepleierrådgiveren, som vet at deltakeren er en god kandidat for screeningtester, vil bli opplært til å planlegge CRC- eller BC-screeningavtaler eller til å sende FOBT-sett til enkeltpersoner i intervensjonsgruppene selv om de ikke har hatt et nylig klinikkbesøk.
Andre navn:
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Hva måler studien?
Primære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
|---|---|---|
|
Primært utfall - forskjeller i CRC-screening-overholdelse, ved kontroll for overholdelse av BC-screening ved baseline, blant kvinner som er randomisert til 1) vanlig omsorg; 2) en TIWeb; 3) en CSC, og 4) en TIWeb pluss en CSC.
Tidsramme: 6 måneder fra grunnmålet
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enhver CRC-test (enten en avføringstest eller koloskopi) mottak av en avføringstest eller en koloskopi
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6 måneder fra grunnmålet
|
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Primært utfall: forskjeller i adopsjonsstadium (prekontemplasjon, kontemplasjon, handling) ved kontroll for overholdelse av BC-screening ved baseline, blant kvinner som er randomisert til 1) vanlig omsorg; 2) en TIWeb; 3) en CSC, og 4) en TIWeb pluss en CSC.
Tidsramme: 6 måneder fra grunnmålet
|
Fremover scenebevegelse er det ønskede resultatet - som bestemmer enhver fremadgående scenebevegelse ved å vurdere CRC-screening enten fra forhåndskontemplasjon til kontemplasjon eller fra prekontemplasjon til handling
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6 måneder fra grunnmålet
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Sekundære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
|---|---|---|
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Sekundært resultat: Intervensjonskostnader
Tidsramme: 6 måneder fra grunnmålet
|
Ved å sammenligne kostnadseffektiviteten til fire forhold for å fremme CRC- og BC-screening, vil det være forskjeller i overholdelse av både CRC- og BC-screening og adopsjonsstadium, blant kvinner som er randomisert til 1) vanlig omsorg; 2) en TIWeb; 3) en CSC, og 4) en TIWeb pluss en CSC.
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6 måneder fra grunnmålet
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Samarbeidspartnere og etterforskere
Det er her du vil finne personer og organisasjoner som er involvert i denne studien.
Sponsor
Samarbeidspartnere
Etterforskere
- Hovedetterforsker: Victoria Champion, PhD, Indiana University School of Medicine
Publikasjoner og nyttige lenker
Den som er ansvarlig for å legge inn informasjon om studien leverer frivillig disse publikasjonene. Disse kan handle om alt relatert til studiet.
Generelle publikasjoner
- Ware J Jr, Kosinski M, Keller SD. A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996 Mar;34(3):220-33. doi: 10.1097/00005650-199603000-00003.
- Mandel JS, Bond JH, Church TR, Snover DC, Bradley GM, Schuman LM, Ederer F. Reducing mortality from colorectal cancer by screening for fecal occult blood. Minnesota Colon Cancer Control Study. N Engl J Med. 1993 May 13;328(19):1365-71. doi: 10.1056/NEJM199305133281901. Erratum In: N Engl J Med 1993 Aug 26;329(9):672.
- Prochaska JO, Velicer WF. The transtheoretical model of health behavior change. Am J Health Promot. 1997 Sep-Oct;12(1):38-48. doi: 10.4278/0890-1171-12.1.38.
- American Cancer Society. Cancer Facts and Figures, 2008. American Cancer Society. 2008.
- Smith RA, Cokkinides V, Eyre HJ. American Cancer Society guidelines for the early detection of cancer, 2006. CA Cancer J Clin. 2006 Jan-Feb;56(1):11-25; quiz 49-50. doi: 10.3322/canjclin.56.1.11.
- American Cancer Society. Report finds historic drop in total number of cancer deaths. 2006 [updated 2006; cited]; Available from: http://www.cancer.org/docroot/MED/content/MED_2_lx_American_Cancer_Society_Report_Finds_Drop _in_Total_Cancer_Deaths.asp
- Breen N, A Cronin K, Meissner HI, Taplin SH, Tangka FK, Tiro JA, McNeel TS. Reported drop in mammography : is this cause for concern? Cancer. 2007 Jun 15;109(12):2405-9. doi: 10.1002/cncr.22723.
- Prochaska JJ, Spring B, Nigg CR. Multiple health behavior change research: an introduction and overview. Prev Med. 2008 Mar;46(3):181-8. doi: 10.1016/j.ypmed.2008.02.001. Epub 2008 Feb 6.
- Stockwell DH, Woo P, Jacobson BC, Remily R, Syngal S, Wolf J, Farraye FA. Determinants of colorectal cancer screening in women undergoing mammography. Am J Gastroenterol. 2003 Aug;98(8):1875-80. doi: 10.1111/j.1572-0241.2003.07577.x.
- Solomon D, Breen N, McNeel T. Cervical cancer screening rates in the United States and the potential impact of implementation of screening guidelines. CA Cancer J Clin. 2007 Mar-Apr;57(2):105-11. doi: 10.3322/canjclin.57.2.105.
- Katz ML, Tatum CM, Degraffinreid CR, Dickinson S, Paskett ED. Do cervical cancer screening rates increase in association with an intervention designed to increase mammography usage? J Womens Health (Larchmt). 2007 Jan-Feb;16(1):24-35. doi: 10.1089/jwh.2006.0071.
- Champion VL. Strategies to increase mammography utilization. Med Care. 1994 Feb;32(2):118-29. doi: 10.1097/00005650-199402000-00003.
- Skinner CS, Strecher VJ, Hospers H. Physicians' recommendations for mammography: do tailored messages make a difference? Am J Public Health. 1994 Jan;84(1):43-9. doi: 10.2105/ajph.84.1.43.
- Taplin SH, Barlow WE, Ludman E, MacLehos R, Meyer DM, Seger D, Herta D, Chin C, Curry S. Testing reminder and motivational telephone calls to increase screening mammography: a randomized study. J Natl Cancer Inst. 2000 Feb 2;92(3):233-42. doi: 10.1093/jnci/92.3.233.
- American Cancer Society. Cancer Facts & Figures 2009. Atlanta; 2009 Contract No.: Document Number|.
- Shapiro JA, Seeff LC, Nadel MR. Colorectal cancer-screening tests and associated health behaviors. Am J Prev Med. 2001 Aug;21(2):132-7. doi: 10.1016/s0749-3797(01)00329-4.
- Saywell RM Jr, Champion VL, Skinner CS, McQuillen D, Martin D, Maraj M. Cost-effectiveness comparison of five interventions to increase mammography screening. Prev Med. 1999 Nov;29(5):374-82. doi: 10.1006/pmed.1999.0568.
- Saywell RM Jr, Champion VL, Zollinger TW, Maraj M, Skinner CS, Zoppi KA, Muegge CM. The cost effectiveness of 5 interventions to increase mammography adherence in a managed care population. Am J Manag Care. 2003 Jan;9(1):33-44.
- Noar SM, Chabot M, Zimmerman RS. Applying health behavior theory to multiple behavior change: considerations and approaches. Prev Med. 2008 Mar;46(3):275-80. doi: 10.1016/j.ypmed.2007.08.001. Epub 2007 Aug 11.
- Champion V, Springston J, Hui S, Saywell RM, Jr., Zollinger TW, Ray D. Community intervention to increase mammography screening (funded research R01CA77736). Bethesda, MD: National Cancer Institute; 1998-2002 Contract No.: Document Number|.
- American Cancer Society. Cancer prevention & early detection facts & figures 2005. Atlanta: American Cancer Society; 2005 Contract No.: Document Number|.
- Winawer SJ, Fletcher RH, Miller L, Godlee F, Stolar MH, Mulrow CD, Woolf SH, Glick SN, Ganiats TG, Bond JH, Rosen L, Zapka JG, Olsen SJ, Giardiello FM, Sisk JE, Van Antwerp R, Brown-Davis C, Marciniak DA, Mayer RJ. Colorectal cancer screening: clinical guidelines and rationale. Gastroenterology. 1997 Feb;112(2):594-642. doi: 10.1053/gast.1997.v112.agast970594. No abstract available. Erratum In: Gastroenterology 1997 Mar;112(3):1060. Gastroenterology 1998 Mar;114(3):625.
- Shapiro S. Periodic screening for breast cancer: the HIP Randomized Controlled Trial. Health Insurance Plan. J Natl Cancer Inst Monogr. 1997;(22):27-30. doi: 10.1093/jncimono/1997.22.27.
- Tabar L, Fagerberg CJ, Gad A, Baldetorp L, Holmberg LH, Grontoft O, Ljungquist U, Lundstrom B, Manson JC, Eklund G, et al. Reduction in mortality from breast cancer after mass screening with mammography. Randomised trial from the Breast Cancer Screening Working Group of the Swedish National Board of Health and Welfare. Lancet. 1985 Apr 13;1(8433):829-32. doi: 10.1016/s0140-6736(85)92204-4.
- Tabar L, Fagerberg G, Duffy SW, Day NE, Gad A, Grontoft O. Update of the Swedish two-county program of mammographic screening for breast cancer. Radiol Clin North Am. 1992 Jan;30(1):187-210.
- Tabar L, Faberberg G, Day NE, Holmberg L. What is the optimum interval between mammographic screening examinations? An analysis based on the latest results of the Swedish two-county breast cancer screening trial. Br J Cancer. 1987 May;55(5):547-51. doi: 10.1038/bjc.1987.112.
- Nystrom L, Rutqvist LE, Wall S, Lindgren A, Lindqvist M, Ryden S, Andersson I, Bjurstam N, Fagerberg G, Frisell J, et al. Breast cancer screening with mammography: overview of Swedish randomised trials. Lancet. 1993 Apr 17;341(8851):973-8. doi: 10.1016/0140-6736(93)91067-v. Erratum In: Lancet 1993 Nov 27;342(8883):1372.
- Andersson I, Aspegren K, Janzon L, Landberg T, Lindholm K, Linell F, Ljungberg O, Ranstam J, Sigfusson B. Mammographic screening and mortality from breast cancer: the Malmo mammographic screening trial. BMJ. 1988 Oct 15;297(6654):943-8. doi: 10.1136/bmj.297.6654.943.
- Frisell J, Eklund G, Hellstrom L, Lidbrink E, Rutqvist LE, Somell A. Randomized study of mammography screening--preliminary report on mortality in the Stockholm trial. Breast Cancer Res Treat. 1991 Mar;18(1):49-56. doi: 10.1007/BF01975443.
- Roberts MM, Alexander FE, Anderson TJ, Chetty U, Donnan PT, Forrest P, Hepburn W, Huggins A, Kirkpatrick AE, Lamb J, et al. Edinburgh trial of screening for breast cancer: mortality at seven years. Lancet. 1990 Feb 3;335(8684):241-6. doi: 10.1016/0140-6736(90)90066-e.
- Miller AB, Howe GR, Wall C. The National Study of Breast Cancer Screening Protocol for a Canadian Randomized Controlled trial of screening for breast cancer in women. Clin Invest Med. 1981;4(3-4):227-58. No abstract available.
- Miller AB, Baines CJ, To T, Wall C. Canadian National Breast Screening Study: 1. Breast cancer detection and death rates among women aged 40 to 49 years. CMAJ. 1992 Nov 15;147(10):1459-76. Erratum In: Can Med Assoc J 1993 Mar 1;148(5):718.
- Miller AB, Baines CJ, To T, Wall C. Canadian National Breast Screening Study: 2. Breast cancer detection and death rates among women aged 50 to 59 years. CMAJ. 1992 Nov 15;147(10):1477-88. Erratum In: Can Med Assoc J 1993 Mar 1;148(5):718.
- Agency for Healthcare Research and Quality. Screening for breast cancer. Recommendations and rationale: Agency for Healthcare Research and Quality; 2002 February 2002 Contract No.: Document Number|.
- Quigley TF, Davis RH Jr, Larson LW, Leger MM, McNellis R, Muma RD, Toth SA. Making decisions on breast cancer screening. JAAPA. 2002 Jul;15(7):11-3. No abstract available.
- Smith RA, Cokkinides V, Brawley OW. Cancer screening in the United States, 2008: a review of current American Cancer Society guidelines and cancer screening issues. CA Cancer J Clin. 2008 May-Jun;58(3):161-79. doi: 10.3322/CA.2007.0017. Epub 2008 Apr 28.
- Kreuter M, Lezin N, Krueter M, Green L. Community health promotion ideas that work. Boston: Jones and Bartlet; 1998.
- Goldstein MG, Whitlock EP, DePue J; Planning Committee of the Addressing Multiple Behavioral Risk Factors in Primary Care Project. Multiple behavioral risk factor interventions in primary care. Summary of research evidence. Am J Prev Med. 2004 Aug;27(2 Suppl):61-79. doi: 10.1016/j.amepre.2004.04.023.
- Beeker C, Kraft JM, Southwell BG, Jorgensen CM. Colorectal cancer screening in older men and women: qualitative research findings and implications for intervention. J Community Health. 2000 Jun;25(3):263-78. doi: 10.1023/a:1005104406934.
- Price JH, Colvin TL, Smith D. Prostate cancer: perceptions of African-American males. J Natl Med Assoc. 1993 Dec;85(12):941-7.
- Myers RE, Trock BJ, Lerman C, Wolf T, Ross E, Engstrom PF. Adherence to colorectal cancer screening in an HMO population. Prev Med. 1990 Sep;19(5):502-14. doi: 10.1016/0091-7435(90)90049-p.
- Farrands PA, Hardcastle JD, Chamberlain J, Moss S. Factors affecting compliance with screening for colorectal cancer. Community Med. 1984 Feb;6(1):12-9. No abstract available.
- Brown ML, Potosky AL, Thompson GB, Kessler LG. The knowledge and use of screening tests for colorectal and prostate cancer: data from the 1987 National Health Interview Survey. Prev Med. 1990 Sep;19(5):562-74. doi: 10.1016/0091-7435(90)90054-n.
- Manne S, Markowitz A, Winawer S, Meropol NJ, Haller D, Rakowski W, Babb J, Jandorf L. Correlates of colorectal cancer screening compliance and stage of adoption among siblings of individuals with early onset colorectal cancer. Health Psychol. 2002 Jan;21(1):3-15.
- Myers RE, Ross E, Jepson C, Wolf T, Balshem A, Millner L, Leventhal H. Modeling adherence to colorectal cancer screening. Prev Med. 1994 Mar;23(2):142-51. doi: 10.1006/pmed.1994.1020. Erratum In: Prev Med 1994 Jul;23(4):545.
- Polednak AP. Knowledge of colorectal cancer and use of screening tests in persons 40-74 years of age. Prev Med. 1990 Mar;19(2):213-26. doi: 10.1016/0091-7435(90)90022-c.
- Manne S, Markowitz A, Winawer S, Guillem J, Meropol NJ, Haller D, Jandorf L, Rakowski W, Babb J, Duncan T. Understanding intention to undergo colonoscopy among intermediate-risk siblings of colorectal cancer patients: a test of a mediational model. Prev Med. 2003 Jan;36(1):71-84. doi: 10.1006/pmed.2002.1122.
- Rawl SM, Menon U, Champion VL, May FE, Loehrer P Sr, Hunter C, Azzouz F, Monahan PO, Skinner CS. Do benefits and barriers differ by stage of adoption for colorectal cancer screening? Health Educ Res. 2005 Apr;20(2):137-48. doi: 10.1093/her/cyg110. Epub 2004 Aug 16.
- Champion VL, Skinner CS. Differences in perceptions of risk, benefits, and barriers by stage of mammography adoption. J Womens Health (Larchmt). 2003 Apr;12(3):277-86. doi: 10.1089/154099903321667618.
- Madlensky L, Esplen MJ, Gallinger S, McLaughlin JR, Goel V. Relatives of colorectal cancer patients: factors associated with screening behavior. Am J Prev Med. 2003 Oct;25(3):187-94. doi: 10.1016/s0749-3797(03)00202-2.
- Hay JL, Buckley TR, Ostroff JS. The role of cancer worry in cancer screening: a theoretical and empirical review of the literature. Psychooncology. 2005 Jul;14(7):517-34. doi: 10.1002/pon.864.
- Andersen MR, Smith R, Meischke H, Bowen D, Urban N. Breast cancer worry and mammography use by women with and without a family history in a population-based sample. Cancer Epidemiol Biomarkers Prev. 2003 Apr;12(4):314-20.
- Skinner CS, Champion VL, Menon U, Seshadri R. Racial and educational differences in mammography-related perceptions among 1,336 nonadherent women. Journal of Psychosocial Oncology. 2002;20:1-18.
- Lauver DR, Henriques JB, Settersten L, Bumann MC. Psychosocial variables, external barriers, and stage of mammography adoption. Health Psychol. 2003 Nov;22(6):649-53. doi: 10.1037/0278-6133.22.6.649.
- Taylor R, Ivanov O, Page A, Brotherton J, Achat H, Close G. Predictors of non-attendance from BreastScreen NSW in women who report current mammography screening. Aust N Z J Public Health. 2003 Dec;27(6):581-7. doi: 10.1111/j.1467-842x.2003.tb00603.x.
- Friedman LC, Webb JA, Richards CS, Plon SE. Psychological and behavioral factors associated with colorectal cancer screening among Ashkenazim. Prev Med. 1999 Aug;29(2):119-25. doi: 10.1006/pmed.1999.0508.
- Gordon NP, Rundall TG, Parker L. Type of health care coverage and the likelihood of being screened for cancer. Med Care. 1998 May;36(5):636-45. doi: 10.1097/00005650-199805000-00004.
- Holt WS Jr. Factors affecting compliance with screening sigmoidoscopy. J Fam Pract. 1991 Jun;32(6):585-9.
- Leard LE, Savides TJ, Ganiats TG. Patient preferences for colorectal cancer screening. J Fam Pract. 1997 Sep;45(3):211-8.
- Lewis SF, Jensen NM. Screening sigmoidoscopy. Factors associated with utilization. J Gen Intern Med. 1996 Sep;11(9):542-4. doi: 10.1007/BF02599602.
- McCarthy BD, Moskowitz MA. Screening flexible sigmoidoscopy: patient attitudes and compliance. J Gen Intern Med. 1993 Mar;8(3):120-5. doi: 10.1007/BF02599753.
- Rawl SM, Menon U, Champion VL, Foster JL, Skinner CS. Colorectal cancer screening beliefs. Focus groups with first-degree relatives. Cancer Pract. 2000 Jan-Feb;8(1):32-7. doi: 10.1046/j.1523-5394.2000.81006.x.
- Lipkus IM, Rimer BK, Halabi S, Strigo TS. Can tailored interventions increase mammography use among HMO women? Am J Prev Med. 2000 Jan;18(1):1-10. doi: 10.1016/s0749-3797(99)00106-3.
- Rakowski W, Ehrich B, Goldstein MG, Rimer BK, Pearlman DN, Clark MA, Velicer WF, Woolverton H 3rd. Increasing mammography among women aged 40-74 by use of a stage-matched, tailored intervention. Prev Med. 1998 Sep-Oct;27(5 Pt 1):748-56. doi: 10.1006/pmed.1998.0354.
- Noar SM, Benac CN, Harris MS. Does tailoring matter? Meta-analytic review of tailored print health behavior change interventions. Psychol Bull. 2007 Jul;133(4):673-93. doi: 10.1037/0033-2909.133.4.673.
- King ES, Rimer BK, Seay J, Balshem A, Engstrom PF. Promoting mammography use through progressive interventions: is it effective? Am J Public Health. 1994 Jan;84(1):104-6. doi: 10.2105/ajph.84.1.104.
- Marcus AC, Bastani R, Reardon K, Karlins S, Das IP, Van Herle MP, McClatchey MW, Crane LA. Proactive screening mammography counseling within the Cancer Information Service: results from a randomized trial. J Natl Cancer Inst Monogr. 1993;(14):119-29.
- Rimer BK, Halabi S, Sugg Skinner C, Lipkus IM, Strigo TS, Kaplan EB, Samsa GP. Effects of a mammography decision-making intervention at 12 and 24 months. Am J Prev Med. 2002 May;22(4):247-57. doi: 10.1016/s0749-3797(02)00417-8.
- Champion VL, Skinner CS, Menon U, Seshadri R, Anzalone DC, Rawl SM. Comparisons of tailored mammography interventions at two months postintervention. Ann Behav Med. 2002 Summer;24(3):211-8. doi: 10.1207/S15324796ABM2403_06.
- Kreuter MW, Farrell D, Olevitch L, Brennan L. Tailoring health messages: customizing communication with computer technology. Mahwah: Lawrence Erlbaum Associates; 2000.
- Champion VL, Springston JK, Zollinger TW, Saywell RM Jr, Monahan PO, Zhao Q, Russell KM. Comparison of three interventions to increase mammography screening in low income African American women. Cancer Detect Prev. 2006;30(6):535-44. doi: 10.1016/j.cdp.2006.10.003. Epub 2006 Nov 15.
- Skinner CS, Kobrin SC, Monahan PO, Daggy J, Menon U, Todora HS, Champion VL. Tailored interventions for screening mammography among a sample of initially non-adherent women: when is a booster dose important? Patient Educ Couns. 2007 Jan;65(1):87-94. doi: 10.1016/j.pec.2006.06.013. Epub 2006 Jul 26.
- Strecher VJ, Kreuter M, Den Boer DJ, Kobrin S, Hospers HJ, Skinner CS. The effects of computer-tailored smoking cessation messages in family practice settings. J Fam Pract. 1994 Sep;39(3):262-70.
- Skinner CS, Campbell MK, Rimer BK, Curry S, Prochaska JO. How effective is tailored print communication? Ann Behav Med. 1999 Fall;21(4):290-8. doi: 10.1007/BF02895960.
- Clark MA, Rakowski W, Ehrich B, Rimer BK, Velicer WF, Dube CE, Pearlman DN, Peterson KK, Goldstein M. The effect of a stage-matched and tailored intervention on repeat mammography(1). Am J Prev Med. 2002 Jan;22(1):1-7. doi: 10.1016/s0749-3797(01)00406-8.
- Jerant A, Kravitz RL, Rooney M, Amerson S, Kreuter M, Franks P. Effects of a tailored interactive multimedia computer program on determinants of colorectal cancer screening: a randomized controlled pilot study in physician offices. Patient Educ Couns. 2007 Apr;66(1):67-74. doi: 10.1016/j.pec.2006.10.009. Epub 2006 Dec 6.
- Powe BD, Weinrich S. An intervention to decrease cancer fatalism among rural elders. Oncol Nurs Forum. 1999 Apr;26(3):583-8.
- Powe BD. Promoting fecal occult blood testing in rural African American women. Cancer Pract. 2002 May-Jun;10(3):139-46. doi: 10.1046/j.1523-5394.2002.103008.x.
- Tilley BC, Vernon SW, Myers R, Glanz K, Lu M, Hirst K, Kristal AR. The Next Step Trial: impact of a worksite colorectal cancer screening promotion program. Prev Med. 1999 Mar;28(3):276-83. doi: 10.1006/pmed.1998.0427.
- Pignone M, Harris R, Kinsinger L. Videotape-based decision aid for colon cancer screening. A randomized, controlled trial. Ann Intern Med. 2000 Nov 21;133(10):761-9. doi: 10.7326/0003-4819-133-10-200011210-00008.
- Wardle J, Williamson S, McCaffery K, Sutton S, Taylor T, Edwards R, Atkin W. Increasing attendance at colorectal cancer screening: testing the efficacy of a mailed, psychoeducational intervention in a community sample of older adults. Health Psychol. 2003 Jan;22(1):99-105. doi: 10.1037//0278-6133.22.1.99.
- Rimal RN, Flora JA. Interactive technology attributes in health promotion: practical and theoretical issues. In: Street RL, Gold WR, Manning T, editors. Health Promotion and Interactive Technology: Theoretical Applications and Future Directions. Mahwah: Lawrence Erlbaum Associates; 1997. p. 19- 38.
- Ellis LB. Computer-based patient education. Prim Care. 1985 Sep;12(3):547-55.
- Ellis LB, Raines JR. Health education using microcomputers: initial acceptability. Prev Med. 1981 Jan;10(1):77-84. doi: 10.1016/0091-7435(81)90008-6. No abstract available.
- Vargo G. Computer assisted patient education in the ambulatory care setting. Comput Nurs. 1991 Sep-Oct;9(5):168-9. No abstract available.
- Luker KA, Box D. The response of nurses towards the management and teaching of patients on continuous ambulatory peritoneal dialysis (CAPD). Int J Nurs Stud. 1986;23(1):51-9. doi: 10.1016/0020-7489(86)90037-4.
- Pingree S, Hawkins RP, Gustafson DH, Boberg E, Bricker E, Wise M, et al. Will the disadvantaged ride the information highway? Hopeful answers from a computer-based health crisis system. Journal of Broadcasting & Electronic Media. 1996;40(3):331-53.
- Lewis D. Computer-based approaches to patient education: a review of the literature. J Am Med Inform Assoc. 1999 Jul-Aug;6(4):272-82. doi: 10.1136/jamia.1999.0060272.
- Tamm EP, Raval BK, Huynh PT. Evaluation of the quality of self-education mammography material available for patients on the Internet. Acad Radiol. 2000 Mar;7(3):137-41. doi: 10.1016/s1076-6332(00)80113-0.
- Shaw MJ, Beebe TJ, Tomshine PA, Adlis SA, Cass OW. A randomized, controlled trial of interactive, multimedia software for patient colonoscopy education. J Clin Gastroenterol. 2001 Feb;32(2):142-7. doi: 10.1097/00004836-200102000-00010.
- CDRinfo.com. Blu-ray penetration on Rise, Report Says2008 [cited 2008 October 20]: Available from: http://www.cdrinfo.com/sections/news/Details.aspx?NewsId=22933.
- Nielsen. Neilsen Media Report. 2008 [updated 2008; cited 2008 September 15]; Available from: htpp://www.nielsenmedia.com.
- Sarfaty M, Wender R. How to increase colorectal cancer screening rates in practice. CA Cancer J Clin. 2007 Nov-Dec;57(6):354-66. doi: 10.3322/CA.57.6.354.
- Stone EG, Morton SC, Hulscher ME, Maglione MA, Roth EA, Grimshaw JM, Mittman BS, Rubenstein LV, Rubenstein LZ, Shekelle PG. Interventions that increase use of adult immunization and cancer screening services: a meta-analysis. Ann Intern Med. 2002 May 7;136(9):641-51. doi: 10.7326/0003-4819-136-9-200205070-00006.
- Castro CM, King AC. Telephone-assisted counseling for physical activity. Exerc Sport Sci Rev. 2002 Apr;30(2):64-8. doi: 10.1097/00003677-200204000-00004.
- Fox SA, Klos DS, Worthen NJ, Pennington E, Bassett LW, Gold RH. Improving the adherence of urban women to mammography guidelines: strategies for radiologists. Radiology. 1990 Jan;174(1):203-6. doi: 10.1148/radiology.174.1.2294548.
- Frazier AL, Colditz GA, Fuchs CS, Kuntz KM. Cost-effectiveness of screening for colorectal cancer in the general population. JAMA. 2000 Oct 18;284(15):1954-61. doi: 10.1001/jama.284.15.1954.
- Pignone M, Saha S, Hoerger T, Mandelblatt J. Cost-effectiveness analyses of colorectal cancer screening: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med. 2002 Jul 16;137(2):96-104. doi: 10.7326/0003-4819-137-2-200207160-00007.
- Andersen MR, Urban N, Ramsey S, Briss PA. Examining the cost-effectiveness of cancer screening promotion. Cancer. 2004 Sep 1;101(5 Suppl):1229-38. doi: 10.1002/cncr.20511.
- Abrams DB, Mills S, Bulger D. Challenges and future directions for tailored communication research. Ann Behav Med. 1999 Fall;21(4):299-306. doi: 10.1007/BF02895961.
- Emmons KM, McBride CM, Puleo E, Pollak KI, Marcus BH, Napolitano M, Clipp E, Onken J, Farraye FA, Fletcher R. Prevalence and predictors of multiple behavioral risk factors for colon cancer. Prev Med. 2005 May;40(5):527-34. doi: 10.1016/j.ypmed.2004.10.001.
- Prochaska JJ, Sallis JF. A randomized controlled trial of single versus multiple health behavior change: promoting physical activity and nutrition among adolescents. Health Psychol. 2004 May;23(3):314-8. doi: 10.1037/0278-6133.23.3.314.
- Johnson SS, Paiva AL, Cummins CO, Johnson JL, Dyment SJ, Wright JA, Prochaska JO, Prochaska JM, Sherman K. Transtheoretical model-based multiple behavior intervention for weight management: effectiveness on a population basis. Prev Med. 2008 Mar;46(3):238-46. doi: 10.1016/j.ypmed.2007.09.010. Epub 2007 Oct 23.
- Hyman DJ, Pavlik VN, Taylor WC, Goodrick GK, Moye L. Simultaneous vs sequential counseling for multiple behavior change. Arch Intern Med. 2007 Jun 11;167(11):1152-8. doi: 10.1001/archinte.167.11.1152.
- Janz NK, Becker MH. The Health Belief Model: a decade later. Health Educ Q. 1984 Spring;11(1):1-47. doi: 10.1177/109019818401100101.
- Becker MH. The Health Belief Model and personal health behavior. Becker MH, editor. San Francisco: Society for Public Health Education; 1974.
- Rosenstock IM, Strecher VJ, Becker MH. Social learning theory and the Health Belief Model. Health Educ Q. 1988 Summer;15(2):175-83. doi: 10.1177/109019818801500203.
- Janz NK, Wren PA, Schottenfeld D, Guire KE. Colorectal cancer screening attitudes and behavior: a population-based study. Prev Med. 2003 Dec;37(6 Pt 1):627-34. doi: 10.1016/j.ypmed.2003.09.016.
- Coleman EA, O'Sullivan P. Racial differences in breast cancer screening among women from 65 to 74 years of age: trends from 1987-1993 and barriers to screening. J Women Aging. 2001;13(3):23-39. doi: 10.1300/J074v13n03_03.
- Green PM, Kelly BA. Colorectal cancer knowledge, perceptions, and behaviors in African Americans. Cancer Nurs. 2004 May-Jun;27(3):206-15; quiz 216-7. doi: 10.1097/00002820-200405000-00004.
- Cooper GS, Koroukian SM. Racial disparities in the use of and indications for colorectal procedures in Medicare beneficiaries. Cancer. 2004 Jan 15;100(2):418-24. doi: 10.1002/cncr.20014.
- Saywell RM Jr, Champion VL, Skinner CS, Menon U, Daggy J. A cost-effectiveness comparison of three tailored interventions to increase mammography screening. J Womens Health (Larchmt). 2004 Oct;13(8):909-18. doi: 10.1089/jwh.2004.13.909.
- Champion V, Huster G. Effect of interventions on stage of mammography adoption. J Behav Med. 1995 Apr;18(2):169-87. doi: 10.1007/BF01857868.
- Skinner CS, Arfken CL, Sykes RK. Knowledge, perceptions, and mammography stage of adoption among older urban women. Am J Prev Med. 1998 Jan;14(1):54-63. doi: 10.1016/s0749-3797(97)00008-1.
- Champion VL, Skinner CS, Foster JL. The effects of standard care counseling or telephone/in-person counseling on beliefs, knowledge, and behavior related to mammography screening. Oncol Nurs Forum. 2000 Nov-Dec;27(10):1565-71.
- Rakowski W, Fulton JP, Feldman JP. Women's decision making about mammography: a replication of the relationship between stages of adoption and decisional balance. Health Psychol. 1993 May;12(3):209-14. doi: 10.1037//0278-6133.12.3.209.
- Rakowski W, Lefebvre RC, Assaf AR, Lasater TM, Carleton RA. Health practice correlates in three adult age groups: results from two community surveys. Public Health Rep. 1990 Sep-Oct;105(5):481-91.
- Hovland CI, Janis IL, Kelley HH. Communication and Persuasion. Psychological studies of opinion change. New Haven: Yale University Press; 1953.
- Petty RE, Cacioppo JT. Attitudes and persuasion--classic and contemporary approaches. Boulder, CO: Westview Press; 1996.
- Champion V, Skinner CS, Menon U. Development of a self-efficacy scale for mammography. Res Nurs Health. 2005 Aug;28(4):329-36. doi: 10.1002/nur.20088.
- Lairson DR, DiCarlo M, Myers RE, Wolf T, Cocroft J, Sifri R, Rosenthal M, Vernon SW, Wender R. Cost-effectiveness of targeted and tailored interventions on colorectal cancer screening use. Cancer. 2008 Feb 15;112(4):779-88. doi: 10.1002/cncr.23232.
- Zapka JG, Lemon SC. Interventions for patients, providers, and health care organizations. Cancer. 2004 Sep 1;101(5 Suppl):1165-87. doi: 10.1002/cncr.20504.
- Alexander GL, Divine GW, Couper MP, McClure JB, Stopponi MA, Fortman KK, Tolsma DD, Strecher VJ, Johnson CC. Effect of incentives and mailing features on online health program enrollment. Am J Prev Med. 2008 May;34(5):382-8. doi: 10.1016/j.amepre.2008.01.028.
- Hall KL, Rossi JS. Meta-analytic examination of the strong and weak principles across 48 health behaviors. Prev Med. 2008 Mar;46(3):266-74. doi: 10.1016/j.ypmed.2007.11.006. Epub 2007 Nov 22.
- Rakowski W, Dube CE, Marcus BH, Prochaska JO, Velicer WF, Abrams DB. Assessing elements of women's decisions about mammography. Health Psychol. 1992;11(2):111-8. doi: 10.1037//0278-6133.11.2.111.
- Carlos RC, Fendrick AM, Patterson SK, Bernstein SJ. Associations in breast and colon cancer screening behavior in women. Acad Radiol. 2005 Apr;12(4):451-8. doi: 10.1016/j.acra.2004.12.024.
- Morgan DL. Focus groups as qualitative research. 2nd ed. Thousand Oaks, CA: Sage Publications; 1997.
- Glaser BG, Strauss AL. The discovery of grounded theory: strategies for qualitative research. Paperback ed. Hawthorne, NY: Aldine de Gruyter; 1967.
- Lincoln YS, Guba EG. Naturalistic inquiry. Newbury Park: CA: Sage; 1985.
- Champion VL. Instrument development for health belief model constructs. ANS Adv Nurs Sci. 1984 Apr;6(3):73-85. doi: 10.1097/00012272-198404000-00011.
- Champion VL. Revised susceptibility, benefits, and barriers scale for mammography screening. Res Nurs Health. 1999 Aug;22(4):341-8. doi: 10.1002/(sici)1098-240x(199908)22:43.0.co;2-p.
- Champion VL. Instrument refinement for breast cancer screening behaviors. Nurs Res. 1993 May-Jun;42(3):139-43.
- Rawl S, Champion VL, Menon U, Loehrer P, Vance G, Skinner CS. Validation of scales to measure benefits and barriers to colorectal cancer screening. Journal of Psychosocial Oncology. 2001;19(3/4):47-63.
- Kreuter MW, Strecher VJ. Changing inaccurate perceptions of health risk: results from a randomized trial. Health Psychol. 1995 Jan;14(1):56-63. doi: 10.1037//0278-6133.14.1.56.
- Rawl S, Champion V, Menon U, Loehrer P, Vance G, Hunter C, et al. Differences on health beliefs by stage of readiness to screen for colorectal cancer among first-degree relatives of affected individuals. Ann Behav Med. 2001;23(Supplement):S202.
- Menon U. Factors associated with colorectal cancer screening in an average risk population [Dissertation]. Indianapolis, IN: Indiana University; 2000.
- Hosmer DW, Lemeshow S. Applied logistic regression. 2nd ed. New York: Wiley; 2000.
- Andersen MR, Hager M, Su C, Urban N. Analysis of the cost-effectiveness of mammography promotion by volunteers in rural communities. Health Educ Behav. 2002 Dec;29(6):755-70. doi: 10.1177/109019802237942.
- Chirikos TN, Christman LK, Hunter S, Roetzheim RG. Cost-effectiveness of an intervention to increase cancer screening in primary care settings. Prev Med. 2004 Aug;39(2):230-8. doi: 10.1016/j.ypmed.2004.03.021.
- Gold MR, Gold SR, Weinstein MC. Cost-effectiveness in health and medicine. Marthe R. Gold SRG, Milton C. Weinstein, editor. New York, NY: Oxford University Press; 1996.
- Drummond MF, Sculpher MJ, Torrance GW, O'Brien BJ, Stoddart GL. Methods for the economic evaluation of health care programmes. 3rd ed. Oxford: Oxford University Press; 2005.
- Briggs AH. Handling uncertainty in economic evaluation and presenting the results. Drummond M, Maguire, A., editor. Oxford: Oxford University Press; 2001.
- Westfall PH, Young SS. Resampling-based multiple testing: examples and methods for P-value adjustment. New York: Wiley; 1993.
- SPSS. Statistical package for the social sciences, 15.0 for Windows. 15.0 for Windows ed. Chicago: SPSS, Inc.; 2006.
- Dawson JD. Stratification of summary statistic tests according to missing data patterns. Stat Med. 1994 Sep 30;13(18):1853-63. doi: 10.1002/sim.4780131807.
- Huang D, Lairson DR, Chung TH, Monahan PO, Rawl SM, Champion VL. Economic Evaluation of Web- versus Telephone-based Interventions to Simultaneously Increase Colorectal and Breast Cancer Screening Among Women. Cancer Prev Res (Phila). 2021 Sep;14(9):905-916. doi: 10.1158/1940-6207.CAPR-21-0009. Epub 2021 Jul 9.
- Champion VL, Christy SM, Rakowski W, Lairson DR, Monahan PO, Gathirua-Mwangi WG, Stump TE, Biederman EB, Kettler CD, Rawl SM. An RCT to Increase Breast and Colorectal Cancer Screening. Am J Prev Med. 2020 Aug;59(2):e69-e78. doi: 10.1016/j.amepre.2020.03.008.
- Lairson DR, Chung TH, Huang D, Stump TE, Monahan PO, Christy SM, Rawl SM, Champion VL. Economic Evaluation of Tailored Web versus Tailored Telephone-Based Interventions to Increase Colorectal Cancer Screening among Women. Cancer Prev Res (Phila). 2020 Mar;13(3):309-316. doi: 10.1158/1940-6207.CAPR-19-0376. Epub 2020 Jan 22.
Studierekorddatoer
Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.
Studer hoveddatoer
Studiestart (FAKTISKE)
22. juli 2010
Primær fullføring (FAKTISKE)
15. september 2015
Studiet fullført (FAKTISKE)
31. mai 2017
Datoer for studieregistrering
Først innsendt
22. august 2017
Først innsendt som oppfylte QC-kriteriene
8. september 2017
Først lagt ut (FAKTISKE)
12. september 2017
Oppdateringer av studieposter
Sist oppdatering lagt ut (FAKTISKE)
12. september 2017
Siste oppdatering sendt inn som oppfylte QC-kriteriene
8. september 2017
Sist bekreftet
1. september 2017
Mer informasjon
Begreper knyttet til denne studien
Nøkkelord
Ytterligere relevante MeSH-vilkår
Andre studie-ID-numre
- 1009001808
- 5R01CA136940-05 (NIH)
Plan for individuelle deltakerdata (IPD)
Planlegger du å dele individuelle deltakerdata (IPD)?
JA
IPD-planbeskrivelse
Avidentifisert IPD vil bli gjort tilgjengelig for andre forskere gjennom et HIPAA-kompatibelt datalagringssystem (Box Health) som er passordbeskyttet.
IPD-delingstidsramme
1. januar 2017 - 31. mars 2020.
Tilgangskriterier for IPD-deling
Forskningspersonell som utelukkende er tilknyttet studiet og/eller Graduate- eller Post-Doc-studenter - som skriver relaterte manuskripter - som har fått tillatelse fra hovedetterforskeren, Victoria Champion, kan sende inn en forespørsel.
IPD-deling Støtteinformasjonstype
- STUDY_PROTOCOL
- ICF
- ANALYTIC_CODE
- CSR
Legemiddel- og utstyrsinformasjon, studiedokumenter
Studerer et amerikansk FDA-regulert medikamentprodukt
Nei
Studerer et amerikansk FDA-regulert enhetsprodukt
Nei
Denne informasjonen ble hentet direkte fra nettstedet clinicaltrials.gov uten noen endringer. Hvis du har noen forespørsler om å endre, fjerne eller oppdatere studiedetaljene dine, vennligst kontakt register@clinicaltrials.gov. Så snart en endring er implementert på clinicaltrials.gov, vil denne også bli oppdatert automatisk på nettstedet vårt. .
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